جست‌وجوی استاد و پژوهشگر

• Natural Products
• Ethnobotany
• Cell Signaling
• +۵ مورد دیگر

Roy Golsteyn is a Professor at the University of Lethbridge , affiliated with the Biological Sciences Department . Holding a PhD in Biochemistry from the University of Cambridge, his research focuses on natural products from Canadian plants, particularly through the Prairie to Pharmacy Program , which integrates ethnobotany , imaging technology , and partnerships with First Nation communities . Degrees: PhD Biochemistry (Cambridge), MSc Medical Biochemistry (Calgary), BSc Biological Sciences (Lethbridge) His work explores how natural compounds affect cell cycle regulation , with a focus on mitosis inhibition , genomic instability , and apoptosis in cancer cells. Recent studies include ruthenium complexes targeting cancer pathways and sesquiterpene lactones from prairie flora. Key grants include funding from NSERC , the Canada Foundation for Innovation , and Power Corp. Canada . He has been featured in media outlets like CBC Radio and CTV for his collaborative research and philanthropy. Awards: Government Award, France (2000)

Kate Whiteمشاهده پروفایل

استادیار

• Chemical Biology
• Structural Biology
• Cellular Imaging
• +۴ مورد دیگر

Kate White serves as an Assistant Professor in the Department of Chemistry at the University of Southern California's Dornsife College of Letters, Arts and Sciences, with cross-appointment in Quantitative and Computational Biology. Affiliated with the Bridge Institute, she pioneers experimental and computational tools to bridge structural biology and physiology through multi-scale approaches spanning atomic to cellular resolutions. Education: Ph.D. in Pharmacology, University of North Carolina – Chapel Hill (2014) Research Focus: Her laboratory investigates insulin hormone processing and maturation mechanisms in pancreatic β-cells, employing chemical biology, multi-modal imaging, biophysics, and computational modeling to study peptide hormone secretion. Defects in these processes underlie mental disorders (depression, bipolar) and metabolic diseases (diabetes). Current work defines signaling pathways for hormone maturation, examines inter-organelle communication, characterizes cellular subtypes, and develops community-based modeling tools. Publication Trends: Recent work (2022-2024) demonstrates heavy reliance on soft X-ray tomography and cryo-electron tomography for cellular mapping, combined with dielectrophoresis separation techniques and computational modeling. Key themes include insulin vesicle maturation, beta cell structural heterogeneity during pregnancy, and organelle interaction quantification. Laboratory Structure: The Kate White Lab operates through four integrated research thrusts: (1) signaling pathway characterization for peptide maturation, (2) inter-organelle communication biochemistry, (3) cellular/organelle subtype analysis in secretory cells, and (4) development of next-generation cellular modeling infrastructure for scientific communities.

• Chemical Biology
• Fluorescence Guided Surgery
• Drug Delivery
• +۵ مورد دیگر

Prof. Donal O'Shea is a Professor in the Department of Chemistry at the Royal College of Surgeons in Ireland (RCSI). Previously, he held roles including Head of Pharmaceutical & Medicinal Chemistry at RCSI and Associate Professor/Senior Lecturer at University College Dublin (UCD). He earned a PhD (1993) and BSc (1990) in Chemistry from University College Galway. His research focuses on synthesizing complex molecules for applications in fluorescence-guided surgery , light-activated anti-cancer agents , and nanomedicine . Key areas include near-infrared fluorophores , drug delivery systems , and collaborations with medical imaging. He has led initiatives like the Centre for Synthesis & Chemical Biology at UCD and contributed to projects on exosome imaging and anti-microbial agents. Recent publications highlight innovations in fluorescence imaging probes , vaping health risk modeling , and bioorthogonal reactions . His work aligns with UN Sustainable Development Goal 3 (Good Health). Awards include the 2012 North/South Ireland Lectureship , Teacher of the Year (2008, 2011), and multiple visiting professorships. He has secured grants totaling millions, including SFI-funded projects on super-resolution imaging and colorectal cancer diagnostics . Prof. O'Shea oversees RCSI's Chemistry Department and collaborates internationally. His lab develops tools for real-time cellular imaging and targeted drug delivery , with applications in surgery and oncology.

Norman Van Rhijnمشاهده پروفایل

پژوهشگر ارشد

• Antimicrobial Resistance (AMR)
• Climate Change Impact on Fungal Pathogens
• One Health
• +۳ مورد دیگر

Norman Van Rhijn is a Wellcome Trust Early Career Fellow at the University of Manchester's Division of Evolution, Infection and Genomics. His research focuses on microbial evolution with specific emphasis on fungal pathogens, particularly Aspergillus fumigatus . He leads work on antimicrobial resistance (AMR), climate change impacts on fungal diseases, and genetic tools for non-model organisms. He holds affiliations with MERman (Microbial Evolution Research Manchster) and the Manchester Fungal Infection Group (MFIG). Education: BSc Biology (Leiden University), MSc Medical Mycology (University of Manchester), PhD in Molecular Biology (University of Manchester). Research highlights include developing CRISPR-based genome editing methodologies, studying fungal adaptation to environmental pressures, and investigating dual-use fungicides. His work contributes to UN Sustainable Development Goals related to health and environmental sustainability. Award: Wellcome Trust Early Career Fellowship. Labs/Teams: PI in the MFIG project, editorial board member for mBio , and active in professional societies including the Microbiology Society and British Society for Medical Mycology.

David G. Drubinمشاهده پروفایل

استاد

• Cell Biology
• Actin Dynamics
• Membrane Trafficking
• +۷ مورد دیگر

David G. Drubin is the Ernette Comby Chair in Microbiology and a Professor of Cell Biology, Development and Physiology at the University of California, Berkeley. He is also an affiliate of the Division of Genetics, Genomics and Development, with his lab focusing on molecular mechanisms of actin assembly and membrane trafficking in human stem cells, organoids, zebrafish, and budding yeast. Affiliation: Department of Molecular and Cell Biology, UC Berkeley Research Focus: Actin-mediated membrane trafficking, clathrin-mediated endocytosis, cytoskeletal dynamics, genome editing, stem cell differentiation, and yeast genetics His lab employs real-time imaging, genome editing, mathematical modeling, and biochemical reconstitution to study endocytic mechanisms. Key findings include the role of membrane curvature in endocytosis and the translation of yeast discoveries to mammalian systems. Google Scholar publications up to 2025 highlight his work on myosin-I, actin networks, and membrane biophysics. Lab members include students and researchers like Sun Hae Hong, Yansong Miao, and Nate Krefman. The lab has produced educational videos (e.g., DNA gel training) and maintains active research directions in actin force generation and organelle inheritance pathways.

Andrew J. Broadbentمشاهده پروفایل

استادیار

• Molecular Virology
• Vaccine Development
• Pathogenesis
• +۵ مورد دیگر

Andrew J. Broadbent is an Assistant Professor in the Department of Animal and Avian Sciences at the University of Maryland, College Park, within the College of Agriculture & Natural Resources. His research focuses on the molecular virology of avian viruses, including avian influenza virus (AIV), infectious bursal disease virus (IBDV), and avian reovirus (ARV), with an emphasis on vaccine development, pathogenesis, and zoonotic disease prevention. Education and Experience 2002-2005: MA in Pathology, University of Cambridge 1999-2002: MA in Pathology, University of Cambridge 2006-2010: PhD in Microbiology & Immunology, Imperial College London 2010-2014: Postdoctoral Visiting Fellow, NIH 2014-2019: Research Fellow, The Pirbright Institute 2019-2021: Group Leader, The Pirbright Institute 2020-2021: Teaching Fellow, University of Surrey 2021-Present: Assistant Professor, University of Maryland Research Focus Broadbent's work centers on understanding how avian RNA viruses replicate and cause disease, particularly their interactions with host immune systems. His lab investigates immunosuppression mechanisms, viral evolution, and vaccine efficacy using in vitro and in vivo models like chicken bursal cells and molecular imaging techniques. Article Trends His publications emphasize segmented RNA viruses (IBDV, influenza), viral replication structures (virus factories), immune evasion strategies, and cross-species transmission dynamics. Recent studies explore antigenic drift modeling and zoonotic potential of avian pathogens. Scientific Contributions MPower Partnership Seed Grant ($300,765) for zoonotic virus prevention Involved in six UMD Grand Challenge Grants Elected ASV Veterinary Virology Councilor Students and Lab Current lab members include PhD students Andrew Brodrick and Jyothsna Girish, postdoc Dr. Sofia Egana-Labrin, and technician Alex Broadwway. The lab utilizes primary tissue culture, molecular biology, and bio-imaging to study avian viral diseases.

• Chemical Biology
• Biochemistry
• Cell Biology
• +۵ مورد دیگر

Ciaran Seath is an Assistant Professor of Chemistry at Scripps-UF (The Wertheim Scripps UF Institute) in Jupiter, Florida, where he leads the Seath Research Chemistry Lab. His research focuses on using chemical biology methods to discover new therapeutically relevant protein-biomolecule interactions that contribute to disease. Dr. Seath completed his PhD in chemistry from the University of Strathclyde in 2017 under the supervision of Dr. Allan Watson, studying chemoselective transition-metal catalysis. He then conducted postdoctoral research at Emory University with Professor Nathan Jui, developing novel reductive photoredox methodologies, and at Princeton University with Professors David MacMillan and Tom Muir, exploring photocatalytic methods for proximity labeling in cancer biology. His research interests span several critical areas in chemical biology: New Therapeutic Strategies: Using proximity labeling methods to understand how mutations and post-translational modifications lead to diseased phenotypes Understanding Transcription in Disease: Investigating "undruggable" proteins that control transcriptional activation with the goal of finding new cancer therapies PhotoChemical Biology: Developing new chemical reactions in cells driven by visible light irradiation to modify proteins and biomolecules Dr. Seath's laboratory focuses on using state-of-the-art methods in chemical biology to discover new protein-biomolecule interactions relevant to disease, with particular interest in pediatric brain tumors, biochemistry and cell biology, and clinical and translational science. His recent work demonstrates a strong trend toward developing and applying proximity labeling techniques, particularly photoproximity labeling methods with varying activation wavelengths and spatial resolution, to study protein interactions in complex biological systems. His research bridges chemistry, biology, and medicine, with a clear translational focus on developing new therapeutic approaches for challenging diseases. Dr. Seath has secured multiple research grants as Principal Investigator from prestigious sources including Pfizer Inc, the National Institutes of Health (NIGMS, NCI), and the American Chemical Society Petroleum Research Fund. These grants support his innovative work in chromatin chemical biology, photocatalysis, and epigenetic drug discovery. He is actively involved in translational research at Scripps-UF to understand human disease, with his laboratory (The Laboratory of Subcellular Technologies) focusing on developing new chemical tools to address fundamental biological questions with therapeutic implications.

Martin H. Wührمشاهده پروفایل

دانشیار

• Proteomics
• Cellular Organization
• Molecular Biology
• +۳ مورد دیگر

Martin H. Wühr is an Associate Professor of Molecular Biology and a member of the Lewis-Sigler Institute for Integrative Genomics at Princeton University. He leads the Wuhr Lab, focusing on quantitative proteomics to understand cellular organization. His work investigates how molecules self-organize into organelles and cells, particularly studying nuclear-cytoplasmic proteome partitioning and its impact on biological function. Research employs mass spectrometry-based proteomics combined with computational, biochemical, and imaging approaches, using models like human tissue cells and Xenopus laevis embryos. Key contributions include analyzing protein localization dynamics during embryogenesis and developing novel proteomic methodologies. Recent publications highlight advancements in multiplexed proteomics, nuclear import mechanisms, and microbial nutrient interactions. Awards and grants are not explicitly listed, but his lab’s technical innovations indicate significant field impact. Advising and lab management details are not provided, though collaborations with institutions like MIT and Harvard suggest active academic engagement. Labs/Teams: The Wuhr Lab at Princeton University focuses on systems-level proteomics and cellular organization studies.

Chao Sunمشاهده پروفایل

دانشیار

• Neurobiology
• Molecular Cell Biology
• Nanotechnology and Nanoscience
• +۵ مورد دیگر

Chao Sun is an Associate Professor affiliated with multiple departments at Aarhus University , including the Department of Molecular Biology and Genetics, DANDRITE, the Interdisciplinary Nanoscience Center (INANO-MBG), and the Department of Biomedicine. His research integrates neurobiology , molecular cell biology , and nanotechnology , focusing on proteostasis, synaptic regulation, and advanced imaging techniques. PhD in Chemistry from Cornell University (2013-2018) Research interests include: Cellular neurobiology Proteostasis and protein turnover Super-resolution microscopy applications Proteomics of neuronal compartments Synaptic biology and plasticity Article trends reveal expertise in: Proteasome dynamics in synapses Multi-omics approaches to subcellular protein synthesis Single-molecule imaging in synaptic contexts Quantitative analysis of neuronal protein turnover Collaborations include leading researchers like Poul Nissen and Erin Schuman, with publications in high-impact journals such as Science and Current Opinion in Neurobiology . His work bridges molecular neuroscience with cutting-edge nanoscale imaging technologies.

Thomas Marescaمشاهده پروفایل

دانشیار

• Cell Biology
• Molecular Biology
• Chromosome Segregation
• +۳ مورد دیگر

Thomas Maresca is an Associate Professor in the Biology Department at the University of Massachusetts Amherst, serving as Graduate Program Director for Molecular & Cellular Biology within the Interdisciplinary Doctoral Graduate Program (IDGP). His research laboratory investigates fundamental mechanisms of cell division with institutional affiliation to the university's life sciences division. His academic training includes: Ph.D. in Cell Biology from the University of California at Berkeley (2005) B.S. in Biology from the University of North Carolina at Chapel Hill (1999) Dr. Maresca's research centers on chromosome segregation mechanics during mitosis, employing Drosophila and Xenopus model systems with advanced live-cell imaging techniques. His laboratory specializes in quantifying kinetochore-microtubule interactions , error correction mechanisms , and force generation during cell division. Key approaches include FLIM-FRET biosensors, single-molecule tracking, and micromanipulation in egg extracts to dissect how intrinsically disordered proteins, motor complexes (particularly dynein), and kinase networks (Aurora A/B, MPS1) ensure mitotic fidelity. Current work focuses on spatiotemporal regulation of phosphorylation gradients and mechanical feedback at the kinetochore-microtubule interface. Analysis of his 15 most recent publications reveals a consistent trajectory in mitotic mechanics with increasing emphasis on intrinsically disordered proteins as mechanical regulators and subcellular signaling hubs . His work bridges molecular biophysics with cellular function, demonstrating how microtubule plus-ends act as physical signaling platforms and how kinase crosstalk establishes precise spatiotemporal control during anaphase. Recent methodological innovations include commercial FLIM-FRET adaptation and quantitative force measurements at kinetochores. As Graduate Program Director, Dr. Maresca oversees curriculum development and student mentorship for the Molecular & Cellular Biology track. His laboratory (located in Morrill Science Center IV, Room 436) maintains active research programs in kinetochore mechanics and mitotic regulation, supported by continuous publication output since 2000. Collaborative networks include structural biologists and biophysicists investigating mechanochemical transduction in division processes.

Verena Kriechbaumerمشاهده پروفایل

مدرس ارشد

• Plant Cell Biology
• Protein Biochemistry
• Endoplasmic Reticulum Structure and Function
• +۵ مورد دیگر

Verena Kriechbaumer is a Senior Lecturer in Biotechnology and Plant Sciences at the School of Biological and Medical Sciences, Oxford Brookes University . She is Deputy Director of the Oxford Brookes University Centre for Bioimaging and a leading expert in plant endoplasmic reticulum (ER) structure, membrane proteins, and auxin biosynthesis, utilizing biochemical techniques, high-resolution live cell imaging, and interdisciplinary approaches. Research Focus: Plant cell biology, ER architecture, auxin metabolic pathways, protein-membrane interactions, bioinformatics, and translational projects such as engineering plants to convert methane into biofuel. Key Techniques: FRET-FLIM, light sheet microscopy, single-particle tracking, and optogenetics. Publication Trends: Recent studies emphasize ER-membrane contact sites, organelle interaction networks, and the role of reticulons in viral trafficking and methane monooxygenase expression. Collaborative work spans physics, bioenergy, and industrial biotechnology. Scientific Awards: Fellowship from Korean Federation of Science and Technology Societies (2013) Santander Travel Fellowship (2018) Oxford Brookes Research Excellence Award (2020-21) Grants: Leverhulme Trust grant for "pMMO in plants" (2015-2017), STFC Harwell facility grants (2017-2021), BBSRC funding (2021-2026), and industry collaborations with Porton Biopharma Ltd. Labs & Teams: Leads the Endomembrane Structure and Function Group , collaborates with physicists at STFC Harwell Campus, and contributes to European Commission-funded projects like "Advanced Training for Next Generation Scientists in Spatio-Temporal Imaging."

Emily Gibsonمشاهده پروفایل

دانشیار

• Neurophotonics
• Biomedical Optics
• Neural Imaging
• +۴ مورد دیگر

Dr. Emily Gibson is an Associate Professor in the Department of Bioengineering at the University of Colorado School of Medicine. She holds a PhD from the University of Colorado Boulder (2004) and a BS from the Colorado School of Mines (1997). Her multidisciplinary research focuses on developing advanced optical technologies for neuroscience applications. Her primary research interests include: Development of implantable miniature microscopes for two-photon brain imaging in freely behaving animals Superresolution STED microscopy for subcellular imaging of protein dynamics Optical interfaces for neural modulation and sensing in central and peripheral nervous systems Applications in brain mapping, neural circuit analysis, and bioelectronic medicine Dr. Gibson's recent publications demonstrate a strong focus on neurophotonic tool development, including miniature microscopes, fiber-optic imaging systems, and superresolution techniques. Her work consistently applies these technologies to study neural coding, learning mechanisms, and neurodegenerative processes. She leads the Biophotonics Lab at CU Anschutz, which actively develops open-source neurophotonic tools. Current projects include BRAIN Initiative-funded work on voltage imaging and NSF-supported research on odor navigation. Her lab maintains active collaborations with neuroscientists and clinicians to translate optical technologies into neuroscience research and clinical applications.

Paul R. Adamsمشاهده پروفایل

استاد

• Computational Neuroscience
• Theoretical Neuroscience
• Synaptic Plasticity
• +۳ مورد دیگر

Paul R. Adams is a Professor in the Department of Neurobiology and Behavior at Stony Brook University's Renaissance School of Medicine. He joined Stony Brook in 1981 as an Associate Professor and was promoted to Professor in 1984, following prior faculty service at the University of Texas (1977-1981). His educational background includes a B.A. in Physiology and Pharmacology from Cambridge University (1968) and a Ph.D. in Pharmacology from London University (1974). Professor Adams' research centers on computational neuroscience , investigating how synaptic modifications underlying learning are compromised by crosstalk between densely packed synapses. His pioneering Synaptic Darwinism theory proposes evolutionary mechanisms for cortical learning, including "Hebbian proofreading" where layer 6 neurons detect and correct learning errors. He further explores how inter-brain communication networks overcome individual learning failures through information sharing. His publication trajectory reveals consistent focus on mathematical modeling of neural plasticity, evolving from foundational Synaptic Darwinism concepts (1997-2002) to recent work on crosstalk minimization (2013-2014). Key themes include Hebbian learning constraints, cortical circuitry reinterpretation, and theoretical solutions to neural network limitations. Notable honors include the MacArthur Foundation Prize (1986), election as Fellow of the Royal Society (1991), and Howard Hughes Medical Institute Investigatorship (1987-1995). Professor Adams leads theoretical neuroscience research through the Kalypso Mind/Brain Center, collaborating with Research Assistant Professor Kingsley Cox. His HHMI-funded work has influenced understanding of cortical function relevant to autism, schizophrenia, and epilepsy. He serves on editorial boards including Frontiers in Neural Circuits . The Synaptic Darwinism project maintains active investigation into cerebral cortex principles, exploring implications for both neurological disorders and fundamental questions about consciousness.

Xiaonan ZHANGمشاهده پروفایل

دانشیار

• Virology
• Molecular Biology
• Translational Medicine
• +۴ مورد دیگر

Xiaonan ZHANG is an Associate Professor in the Faculty of Science and Technology at the University of Canberra, leading the Hepatitis B Virus (HBV) Group within the Centre for Research into Therapeutic Solutions. He holds a PhD from Fudan University (2012) and previously worked at the Shanghai Public Health Clinical Centre until 2021. His research focuses on HBV molecular pathogenesis, therapeutic vaccine development, and next-generation sequencing applications in viral infections. His work has advanced understanding of HBV’s clinical outcomes, including the discovery of Capsid-Antibody-Complexes (CACs) and their role in pathogenesis. Collaborations span institutions like the Peter Doherty Institute, University of Queensland, and international partners such as Fudan University and University of Duisburg-Essen. Key projects include: Development of therapeutic mRNA vaccines for chronic HBV Clinical evaluation of CAC assays in HBV/HIV co-infections Metagenomic sequencing for pathogen identification Research interests emphasize translational medicine, with contributions to H7N9 influenza and SARS-CoV-2 studies during the pandemic. His team pioneered real-world analyses of viral and host factors in COVID-19 outcomes. Current focus includes liver-resident immune cell dynamics and novel diagnostic assays for HBV nucleic acids. Publications highlight innovations in HBV cccDNA tracking, immune complex mechanisms, and exosome-mediated signaling. No scientific awards were explicitly listed in the provided texts. Xiaonan actively collaborates on grants and supervises PhD students, advancing interdisciplinary approaches to viral diseases.

Joshua Edelمشاهده پروفایل

استاد

• Analytical Chemistry
• Medical Biotechnology
• Human Biophysics
• +۳ مورد دیگر

Joshua Edel is a Professor of Biosensing & Analytical Sciences at Imperial College London's Department of Chemistry within the Faculty of Natural Sciences. He specializes in developing trace analyte analytical platforms, including bioanalytical sensors for clinical applications. His work focuses on single-molecule detection, nanopore sensors, and microfluidic systems. Edel has published over 180 research articles and secured prestigious grants like the ERC Starting Grant (2011) and ERC Consolidator Award (2017). His research spans nanobiotechnology, plasmonic sensors, and biosensor innovation. Education: PhD in developing single-molecule detection within microfluidic systems from Imperial College London (2003). Postdoctoral research at Cornell University (School of Applied and Engineering Physics) and a fellowship at Harvard University's Rowland Institute (single-molecule biophysics). Research Interests: Edel’s lab pioneers techniques such as high-throughput droplet microfluidics, optical/electrical single-molecule sensors, and plasmonic nanopore sensors. His work addresses challenges in diagnostics, nanoelectronics, and structural chemistry. Key areas include developing selective biosensors for clinical samples and advancing nanoscale probing technologies. Grants & Awards: ERC Starting Grant (2011): Rare event bioanalysis ERC Consolidator Award (2017): Selective single-molecule biosensors Funding from EPSRC, Wellcome Trust, and industrial partners Advising & Labs: Edel leads projects in Imperial’s Department of Chemistry and collaborates across disciplines. His lab develops cutting-edge tools like nanoscale tweezers for single-cell analysis and nanofluidic platforms for biomarker detection. He actively consults in biosensing technology.