Yousif Shamoo is the Ralph and Dorothy Looney Professor of BioSciences at Rice University, where he has been a faculty member since 1998. He previously served as Vice Provost for Research (2014-2022) and Director of the Institute of Biosciences and Bioengineering (2008-2014). He holds a Ph.D. in Molecular Biophysics and Biochemistry from Yale University (1988). His research focuses on combating multi-drug resistant bacteria through experimental evolution and biophysical approaches. Key interests include: Evolutionary trajectories of antibiotic resistance in pathogens like Enterococcus and Acinetobacter Biochemical basis of adaptation using microfluidics, genomics, and structural biology Discovery of novel antimicrobial strategies targeting cell membrane stress pathways Microbial interactions in spatially structured environments Publications emphasize antimicrobial resistance mechanisms, evolutionary biophysics, and microfluidic technology development. Recent work explores daptomycin resistance pathways ( LiaFSR ), membrane lipid signaling, and high-throughput evolution platforms. Awards & Honors: AAAS Fellow (2024) Ralph and Dorothy Looney Professorship (2020) George R. Brown Award for Excellence in Teaching (2015) George R. Brown Superior Teaching Award (4×, 2009 onward) ASM Distinguished Lecturer (2011-2013) He leads an active research group funded by NIH and DoD, advising 15+ graduate students. Current projects integrate synthetic biology with Streptomyces-derived drug discovery and microfluidic biosurveillance platforms.











