Harikesh S. Wongمشاهده پروفایل
استادیار
- Immunology
- Cell Biology
- Autoimmunity
- +۳ مورد دیگر
Harikesh S. Wong is an Assistant Professor of Biology and Core Member at the Ragon Institute of MGH, MIT, and Harvard. His research focuses on understanding how immune responses are controlled in tissues to balance host protection against threats like pathogens and tumors while avoiding excessive damage. He combines immunology, microscopy, computational methods, and gene manipulation to study immune response regulation in intact tissues. Education: PhD in 2016 from University of Toronto; BSc in Biochemistry from McMaster University (2010) His lab investigates mechanisms of immune homeostasis, including regulatory T cell feedback circuits and mesoscale T cell antigen discrimination. Recent work explores autoimmune disease susceptibility linked to IL-2 feedback circuit fragility and the role of commensal bacteria in liver immune zonation. Key findings include demonstrating how local regulatory T cells prune self-activated T cells and how interleukin 2 circuitry variations influence autoimmune risk. Articles highlight interdisciplinary approaches to dissect immune system control mechanisms. No scientific awards explicitly mentioned. Grants and advising details are not provided in the text. Labs/Teams: Wong Lab at the Ragon Institute focuses on immune system design principles and disease-related breakdowns in control mechanisms.











