جستجوی استاد راهنمای دانشگاهی

Jennifer Rossمشاهده پروفایل

استاد

• Biophysics
• Soft Matter Physics
• Biological Condensed Matter Physics
• +۵ مورد دیگر

Jennifer Ross is a Professor of Physics and Associate Dean for Creativity, Scholarship, and Research at the College of Arts & Sciences of Syracuse University . As a biophysicist, she investigates how cells organize their interiors through self-assembly and active matter principles, focusing on the microtubule cytoskeleton and enzyme-driven systems using single-molecule imaging . Her research bridges fundamental physics with biological organization . Education: Ph.D. in Physics, University of California, Santa Barbara (2004) B.A. in Physics and Mathematics, Wellesley College (2000) Research Focus: Self-organization of cytoskeletal networks Active matter dynamics in biological systems Motor protein interactions and cargo transport Programming circadian materials via biomolecular systems Microtubule severing mechanisms Recent Article Trends: 2025 studies explore kinesin-driven cytoskeletal composites, urease-DNA origami engineering, and crosslinker-regulated network mechanics 2024-2023 work examines ionic strength effects on microtubules, programmable circadian materials, and motor-cargo dynamics Earlier studies analyze actin-microtubule composites, liquid crystal phase control, and severing enzyme mechanisms Scientific Awards: Fellow of the American Physical Society (APS) and American Association for the Advancement of Science (AAAS) Cottrell Scholar (2025) and STAR Award Margaret Oakley Dayhoff Award (Biophysical Society) Grants: Leads multiple NSF, Sloan Foundation, and Research Corporation grants for projects like "Energy and Entropy Sculpting" and "Explorations: SUPER-Tech SHIP" . Teaching: Offers courses in experimental physics, microscopy, and biophysics, including a globally adopted hands-on microscope-building curriculum. Lab: Heads the Bio-Active Matter Lab , studying how cells harness noisy systems for autonomous organization.

Omar A. Salehمشاهده پروفایل

استاد

• Biophysics
• Soft Matter Physics
• Polymer Physics
• +۵ مورد دیگر

Professor Omar A. Saleh is a distinguished physicist and materials scientist at the University of California, Santa Barbara, holding appointments in both the Materials and Physics Departments. Since summer 2023, he has served as Chair of the Materials Department and maintains a minority appointment in the Biomolecular Science and Engineering (BMSE) Program, where he previously served as Director from 2013-2017. His educational background includes a B.S. in Physics from MIT (1997) and a Ph.D. in Physics from Princeton (2003), supported by a Hertz Fellowship. Following postdoctoral work at École Normale Supérieure in Paris developing single-molecule techniques for motor protein/DNA studies, he joined UCSB in 2005. Saleh's research centers on fundamental principles of biomolecular behavior through experimental investigation of biopolymer elasticity and biomimetic organelles. His lab pioneers precision single-molecule stretching experiments to study entropic/energetic contributions in soft systems and creates life-like behaviors using reconstituted nucleic acid/protein assemblies. Key focus areas include DNA nanostar phase separation, liquid-liquid phase behavior, intrinsically disordered proteins, and non-equilibrium biomolecular systems. His publication trends reveal a strong emphasis on biomolecular condensates (2023-2025), with recurring themes in DNA nanotechnology, polyelectrolyte physics, and single-molecule mechanics. Recent work explores tension-mediated control of phase separation, transcriptional regulation of biomolecular liquids, and active matter principles in DNA systems. NSF CAREER Award (2008) Bessel Research Award from Alexander von Humboldt Society (2017) Fellow of the American Physical Society (2019) Saleh actively mentors graduate students and postdocs including Sam Wilken, Gabrielle Abraham, Anna Nguyen, and Aria Chaderjian, whose research spans DNA nanostar liquids, active droplets, and complex coacervation. His lab develops innovative instrumentation including high-speed magnetic tweezers and GPU-based tracking systems, supported by grants such as NSF/MCB-BSF: Direct force measurements of intrinsically disordered proteins. The Saleh Group operates at BioE 3006, focusing on creating quantitative models of biological function through physical reconstitution.

Sriram Subramaniamمشاهده پروفایل

استاد

• cryo-electron microscopy
• structural biology
• drug-design
• +۴ مورد دیگر

Sriram Subramaniam is a Professor in the Department of Biochemistry and Molecular Biology at the University of British Columbia (UBC) and holds the Gobind Khorana Canada Excellence Research Chair in Precision Cancer Drug Design. His research leverages cryo-electron microscopy (cryo-EM) to advance structural biology and drug design, focusing on protein dynamics and therapeutic target identification. Education: PhD in Physical Chemistry (1987) from Stanford University; MSc in Chemistry (1981) from Indian Institute of Technology, Kanpur. Subramaniam's interdisciplinary work combines cryo-EM with computational tools and molecular biology to study protein structures at atomic resolution. His lab has pioneered cryo-EM applications in precision medicine, including mapping small molecule drugs on patient-specific cancer mutants. Recent publications (2024-2022) highlight his contributions to understanding SARS-CoV-2 immune evasion, structural mechanisms of ATPases, and AI integration in structural biology. His research spans viral entry mechanisms, CRISPR systems, and neurodegenerative disease pathways. Scientific Awards: Gobind Khorana Canada Excellence Research Chair NIH Director’s Award for Scientific Excellence Fellow of the Biophysical Society Breakthrough Prize nomination Based at the Djavad Mowafaghian Center for Brain Health, Subramaniam leads the Program in Cryo-EM Guided Drug Design, contributing to over 177 peer-reviewed publications with a career h-index of 58 and citations exceeding 12,340.

Yaojun Zhangمشاهده پروفایل

استادیار

• Biological Physics
• Biophysics
• Theoretical Physics
• +۳ مورد دیگر

Yaojun Zhang is an Assistant Professor in the Department of Physics & Astronomy and the Department of Biophysics at Johns Hopkins University. She earned her PhD in Physics from the University of California, San Diego (2015), followed by postdoctoral fellowships at the Princeton Center for Theoretical Science (2015-2018) and the Princeton Center for the Physics of Biological Function (2018-2021). Her research focuses on biological physics, particularly the complex behaviors of biomolecules and their assemblies across scales—from single-molecule folding to intracellular transport and biomolecular phase separation. She employs theoretical, mathematical, and computational tools to bridge biological questions with physical principles. Education PhD in Physics, University of California, San Diego (2015) Postdoctoral Fellowships: Princeton University (2015-2021) Research Interests Her group studies biomolecular condensates and liquid-liquid phase separation, exploring how microscopic interactions determine macroscopic properties of cellular compartments. Key areas include: Biomolecular condensate formation and dynamics Phase separation in cellular environments Interactions between biomolecules and cellular components Biophysics of intracellular transport Collaborations & Tools Zhang collaborates with experimentalists to validate theoretical models and develops frameworks for understanding condensate functions, such as surface tension, stoichiometry, and phase diagrams. Her work addresses challenges like condensate stability, molecular exclusion, and biological function regulation. Labs & Resources She leads the Zhang Lab , which integrates experimental and computational approaches. Her team’s research is supported by resources at the Bloomberg Center for Physics and Astronomy.

Frank L. Brownمشاهده پروفایل

استاد

• Physical Chemistry
• Biophysics
• Biomembranes
• +۳ مورد دیگر

Frank L. Brown is a Professor of Chemistry & Biochemistry at the University of California, Santa Barbara, with a joint appointment in Physics and the Biomolecular Sciences & Engineering (BMSE) program. His research focuses on theoretical and computational studies at the interface of physical chemistry and biophysics, particularly biomembrane dynamics and spectroscopy. Dr. Brown received his B.S. in Chemistry and B.A. in Applied Mathematics from UC Berkeley, followed by a Ph.D. in Physical Chemistry from MIT. He has held postdoctoral appointments at UC San Diego and the University of Chicago before joining UCSB in 2001. He is the recipient of prestigious awards including the Alfred P. Sloan Research Fellowship and the Presidential Early Career Award in Science and Engineering. His laboratory employs tools from statistical mechanics, hydrodynamics, and quantum mechanics to study biomembrane structure, dynamics, and interactions with embedded proteins. Key research areas include lipid bilayer fluctuations, membrane protein diffusion, and interpretation of spectroscopic techniques like single-molecule fluorescence and neutron spin echo. Dr. Brown has mentored numerous graduate students and postdoctoral researchers, with notable alumni including Brian Camley, Max Watson, and Golan Bel. His research is supported by grants from agencies such as the National Science Foundation and the Department of Energy. He directs the Brown Research Group, which collaborates with institutions like the CNSI Center for Scientific Computing. His work bridges computational modeling and experimental biophysics, advancing understanding of membrane systems in health and disease.

Shasha Chongمشاهده پروفایل

استادیار

• Transcriptional Regulation
• Intrinsically Disordered Proteins
• Single-Molecule Biophysics
• +۴ مورد دیگر

Shasha Chong is an Assistant Professor of Chemistry at the California Institute of Technology and a Ronald and JoAnne Willens Scholar. She earned her B.S. from the University of Science & Technology of China (2008) and Ph.D. from Harvard University (2014). Her research bridges chemistry, physics, and biology to investigate the molecular mechanisms of cellular processes, focusing on intrinsically disordered regions (IDRs) in transcription proteins. Research Focus: IDRs in transcriptional regulation, cancer biology, liquid-liquid phase separation, and single-molecule imaging techniques. Grants & Awards: CCE Innovation Award (2024), ALSF Innovation Grant, Mallinckrodt Research Grant, Margaret E. Early Medical Research Trust Grant. Collaborations: Caltech-City of Hope Biomedical Research Initiative Grant (2025). Teaching: Co-instructor for courses like Biochemistry Laboratory (Ch 11) and Advanced Topics in Biochemistry (BMB/Bi/Ch 174). Labs & Teams: Leads the Chong Laboratory at Caltech, focusing on interdisciplinary approaches combining single-molecule imaging, genome editing, and bioinformatics.

Vadim Cherezovمشاهده پروفایل

استاد

• Membrane Protein Structure and Function
• G Protein-Coupled Receptors (GPCRs)
• Lipid-Protein Interactions
• +۳ مورد دیگر

Vadim Cherezov, the Ester Dornsife Chair in Biological Sciences and Professor at the University of Southern California (USC), leads groundbreaking research in membrane protein structure and function. Affiliated with the Bridge Institute, Department of Chemistry, and Michelson Center for Convergent Bioscience, his work focuses on GPCRs, ion channels, and transporters—critical targets for drug discovery. His team leverages advanced techniques like Lipidic Cubic Phase (LCP) and Serial Femtosecond Crystallography (SFX) at XFEL facilities to solve high-resolution structures under physiological conditions. Institutional Affiliations: Bridge Institute, USC Michelson Center, Department of Chemistry, Department of Pharmacology and Pharmaceutical Sciences. Key Collaborations: Katritch Lab, Kuhn Lab, NIH, European XFEL. His research explores the role of lipids in modulating GPCR function, addressing diseases like Alzheimer’s, diabetes, and cancer. By solving the structure of the A 2A adenosine receptor via sulfur SAD phasing at XFEL, Cherezov’s lab demonstrated de novo phasing without heavy atoms. This breakthrough enables structural studies of previously intractable membrane proteins. Scientific Awards & Grants: NIH R01 GM108635, U54 GM094618, U54 GM094599, R01 GM095583 Science Signaling Breakthroughs of the Year (2014) Cherezov mentors a dynamic team, including postdocs (e.g., Dong-Gyun Kim), graduate students (e.g., Behnaz Davoudinasab), and alumni (e.g., Benjamin Stauch at Eli Lilly, Nairie Michaelian at Genentech). His lab’s publications span Nature , Science , and Cell , with recent work on Science Advances (2025) addressing ABEL-FRET for GPCR dynamics.

Christoph Schmidtمشاهده پروفایل

استاد

• Biophysics
• Cell Mechanics
• Microrheology
• +۵ مورد دیگر

Christoph F. Schmidt is the Hertha Sponer Distinguished Professor of Physics at Duke University with cross-appointments in the Thomas Lord Department of Mechanical Engineering and Materials Science, Biology, and Biomedical Engineering. He serves as Co-Director of the Duke Materials Initiative and leads an active research program at the intersection of physics and biology. His educational background includes a D.R. from the Technical University of Munich (Germany) in 1988. Schmidt has established himself as a leading researcher in biophysics through decades of innovative work. Professor Schmidt's research spans multiple scales of biological organization, from single molecules to whole organisms. His lab investigates cellular mechanics using advanced techniques including optical trapping, atomic force microscopy, and microrheology. A significant innovation from his group involves single-walled carbon nanotubes for high-bandwidth intracellular tracking. Current research focuses on cardiomyocyte mechanics, Drosophila tissue dynamics, and computational analysis of complex biological systems. His work on motor proteins like Eg5 and ncd has provided fundamental insights into cellular division mechanics. His recent publications (2021-2025) demonstrate increasing integration of computational approaches with experimental biophysics, particularly in analyzing cardiac tissue mechanics and Drosophila sensory systems. The work shows progression from fundamental biophysical measurements toward applications in understanding disease mechanisms and biological function. Professor Schmidt teaches several courses including PHYSICS 995 (Graduate Training Internship), PHYSICS 493 (Research Independent Study), PHYSICS 415 (Biophysics II), PHYSICS 174 (Introduction to Frontiers of Biophysics), and BIOLOGY 425 (Biophysics II). He has successfully mentored numerous graduate students to completion, including recent PhD graduates Dr. Mingru Li and Dr. Xiaoxuan Jian. The Schmidt Lab, part of Duke's Physics Department and the Duke Soft Matter Center, maintains state-of-the-art equipment for optical trapping, atomic force microscopy, and advanced light microscopy. The lab participates in the Triangle Soft Matter Workshop, fostering collaborations with researchers from Duke, UNC Chapel Hill, and NC State University. Current research directions include mechanical responses of suspended cells, tracking non-equilibrium cellular fluctuations, nuclear mechanics, and bacterial membrane mechanics under turgor pressure.

Mark Wallaceمشاهده پروفایل

استاد

• Membrane Biology
• Biophysics
• Optical Microscopy
• +۳ مورد دیگر

Mark Wallace is a Professor of Chemistry at King's College London, affiliated with the Department of Chemistry and the Faculty of Natural, Mathematical & Engineering Sciences. He holds a Royal Society University Research Fellowship (2005–2016) and has been a lecturer at Oxford University before joining King's in 2016. His research focuses on membrane protein function and artificial membrane mimics, combining optical microscopy and nanotechnology. He earned a PhD from the University of Cambridge (2002) and postdoctoral training at Stanford University and the National Institute for Medical Research. Key research interests include membrane protein dynamics, lipid bilayer engineering, and single-molecule imaging. He has pioneered techniques like droplet interface bilayers and interferometric scattering microscopy. His work has led to patents and applications in molecular sensing and medical research. Awards include the 2002 Gregorio Weber Prize and the 2015 RSC Norman Heatley Award. He is actively involved in public outreach, including video podcasts and educational competitions. Recent publications emphasize artificial ion channels, nanoparticle formation monitoring, and mitochondrial protein dynamics. His lab collaborates with institutions like the London Centre for Nanotechnology and the Rosalind Franklin Institute. Over 30 students and researchers have been mentored, with active grants from EPSRC, Wellcome Trust, and BBSRC.

Frank L. H. Brownمشاهده پروفایل

استاد

• Theoretical Biophysics
• Physical Chemistry
• Statistical Mechanics
• +۴ مورد دیگر

Frank L. H. Brown is a Professor at the University of California, Santa Barbara with joint appointments in the Department of Physics and Department of Chemistry and Biochemistry. His research focuses on theoretical and computational approaches to understanding biomembrane dynamics and related biophysical phenomena, situated within the College of Letters and Science. Dr. Brown's research interests span the interface between physical chemistry and biophysics. He employs a variety of theoretical tools including statistical mechanics , hydrodynamics , elasticity theory , and quantum mechanics to study complex biological systems. His work particularly emphasizes the dynamics and structure of biomembranes and the interpretation of various spectroscopy experiments including single molecule fluorescence, neutron spin echo, and flicker spectroscopy. Analysis of his publication record reveals a consistent focus on computational modeling of lipid bilayers, membrane proteins, and related phenomena, with particular emphasis on developing novel theoretical frameworks for understanding membrane behavior across multiple scales. Dr. Brown leads an active research group that includes current members Ehsan Noruzifar (Postdoctoral Researcher) and Sean Cray (Graduate Student). His former group members include numerous successful scientists such as Grace Brannigan, Brian Camley, Lawrence Lin, and Max Watson who completed their graduate studies under his supervision, along with several postdoctoral researchers. His research has been supported by funding that enables theoretical and computational investigations of biomembrane systems. The Brown Research Group operates at the intersection of physics, chemistry, and biology, with facilities connected to the Biomolecular Sciences & Engineering Program and the California NanoSystems Institute (CNSI) at UCSB. Their work combines advanced computational techniques with theoretical physics to address fundamental questions about soft and living matter systems, particularly at biological interfaces.

• Biophysics
• Membrane Proteins
• Structural Biology
• +۳ مورد دیگر

Dr. Lukas Frey is a Researcher at ETH Zurich, affiliated with the Chair of Physical Chemistry and the Institute of Molecular Physical Sciences (IMPS). His work focuses on biophysical studies of membrane proteins, lipid dynamics, and protein aggregation mechanisms. Key research areas include structural biology of ion channels, NMR spectroscopy of membrane proteins in nanodiscs, and the role of lipid environments in modulating protein dynamics. Frey employs advanced techniques like mass photometry and solid-state NMR to investigate molecular mechanisms in biological systems. His recent studies address amyloid fibril formation, pH-dependent α-synuclein polymorphism, and cholesterol-mediated modulation of membrane protein behavior. Based at the HCI F 228 facility in Zurich, Frey collaborates on projects involving lipid bilayer environments, ion channel function, and the structural basis of protein aggregation. His email is lukas.frey@phys.chem.ethz.ch, and he holds an ORCID identifier 0000-0002-1052-1104. Research contributions span from fundamental biophysical insights to methodological advancements in membrane protein analysis.

Markus Heinonenمشاهده پروفایل

پژوهشگر ارشد

• Machine Learning
• Probabilistic Modeling
• Bayesian Inference
• +۵ مورد دیگر

Markus Heinonen is an Academy Research Fellow at Aalto University's Department of Computer Science within the School of Science. His academic position is tied to Harri Lähdesmäki's Professorship, focusing on probabilistic machine learning. He holds a Doctoral degree in Engineering and Technology from the University of Helsinki (2013). His research integrates probabilistic modeling , deep learning , and differential equations , with applications in computational biology, drug discovery, and biophysics. Key themes include Gaussian processes, Bayesian inference, generative models, and their use in understanding complex biological systems like immune cell behavior (e.g., T cell receptor analysis in aplastic anemia) and molecular design. He leads major projects such as the Deep Learning with Differential Equations initiative (2020–2025), exploring continuous-time models and physics-informed neural networks. His work bridges theory and application, evidenced by collaborations in diffusion models , optimal transport , and single-cell analysis . Publications span over 65 peer-reviewed outputs, with recent emphases on robust neural network training, multi-target molecular prediction, and interpretable drug design frameworks. His research contributes to UN Sustainable Development Goal 3 (Good Health) through advancements in disease modeling and therapeutic development. He has undertaken visiting research roles at the University of California, San Francisco (2017) and Telecom ParisTech (2013–2014). Media highlights include recognition for work on TCR-epitope prediction and AI-driven enzyme engineering.

Matthew Lakinمشاهده پروفایل

دانشیار

• Molecular Computing
• DNA Nanotechnology
• Synthetic Biology
• +۷ مورد دیگر

Matthew Lakin is an Associate Professor with tenure in the Department of Computer Science at the University of New Mexico, with a courtesy appointment in the Department of Chemical & Biological Engineering. He is affiliated with the UNM Center for Biomedical Engineering and the School of Engineering, and collaborates extensively with the UNM Health Sciences Center and external institutions. Education: Ph.D., Computer Science, University of Cambridge, 2010 M.A. (Cantab), University of Cambridge, 2009 B.A. (Hons), Computer Science, University of Cambridge, 2005 Dr. Lakin's research focuses on molecular computing, DNA nanotechnology, synthetic biology, and formal verification of biomolecular circuits. He develops computational models and experimental systems for programmable biological devices, especially using heterochiral DNA to enhance stability in living cells. His work spans software tools for biodesign and experimental validation in mammalian systems, with applications in nanomedicine and biosensing. The recent publications highlight a strong trend in engineering robust, intelligent biomolecular systems. His work integrates machine learning concepts into chemical reaction networks, advances geometric modeling of DNA systems, and pioneers L-DNA-based circuits for intracellular applications. The research spans theoretical foundations, software tools, and wet-lab experimentation, emphasizing interdisciplinary innovation. Scientific Awards: Presidential Early Career Award for Scientists and Engineers (PECASE), 2025 NSF CAREER Award, 2021 UNM School of Engineering Junior Faculty Research Excellence Award, 2021 Multiple student awards under his mentorship, including the Outstanding Graduate Student Award and DNA28 Best Student Presentation recognition Dr. Lakin has advised numerous graduate and undergraduate students, including Ph.D. graduates in Biomedical Engineering and Computer Science. He leads major funded projects such as the NSF CAREER grant on heterochiral molecular computing, an EPSCoR Research Fellowship, and a $3M NSF grant on heavy metal biosensing in collaboration with Native American communities. He is also PI on multiple NSF grants related to synthetic cells and nucleic acid technologies. He directs the Lakin Lab for Programmable Biology, which operates within the Department of Computer Science and collaborates with Chemical & Biological Engineering and the Center for Biomedical Engineering. The lab emphasizes both computational modeling and experimental molecular biology, and runs an NSF-funded biotechnology summer camp in partnership with ¡Explora! science museum to strengthen STEM education in New Mexico.

• Biophysical Immunology
• Mechanobiology
• Microscopy Technology
• +۳ مورد دیگر

Marco Fritzsche is a Professor of Biophysical Immunology at the University of Oxford. He serves as the Scientific Director of the Oxford-ZEISS Centre of Excellence and leads the Biophysical Immunology Laboratory (www.bpi-oxford.com), which operates at the intersection of biophysics and immunology. BSc in Mathematics (2003–2006), University of Saarbrücken BSc in Physics (2003–2006), University of Saarbrücken MSc in Theoretical Physics (2006–2008), University of Saarbrücken PhD in Experimental Physics and Biology (2008–2012), University College London His research focuses on biophysical and mechanobiological mechanisms governing immune responses in health and disease. The BPI Laboratory develops advanced microscopy technologies to study these processes, integrating theoretical physics with experimental immunology. Recent publications highlight his work in quantitative imaging of biomolecular organization , traction force microscopy for immune cell dynamics, and trans-synaptic vesicle analysis in T-cell interactions. His studies bridge disciplines like biophysics, immunology, and cell mechanics. Rosalind Franklin Kennedy Trust Research Fellow The BPI Laboratory collaborates with institutions such as the Howard Hughes Medical Institute Janelia Farm and the Rosalind Franklin Institute . His roles include leadership in the Oxford-ZEISS Centre of Excellence and contributions to cutting-edge immunology research.

• MEMS
• Nanotechnology
• BioMEMS
• +۷ مورد دیگر

Cagri A. Savran is a Professor of Mechanical Engineering at Purdue University, with courtesy appointments in Biomedical Engineering and Electrical and Computer Engineering. He holds a B.S. from Purdue University (1998), an M.S. and Ph.D. from MIT (2000 and 2004, respectively). His research focuses on MEMS, nanotechnology, and biosensors, particularly in protein detection, aptamers, and biomedical applications. His work spans fluid mechanics, systems control, and micro/nano fabrication. Education: B.S., Purdue University, 1998 M.S., MIT, 2000 Ph.D., MIT, 2004 Research Interests: Dr. Savran pioneers innovations in bioMEMS and nanoscale biosensing technologies. His lab develops platforms like immunomagnetic diffractometry and microfluidic systems for real-time pathogen detection and clinical diagnostics. Key areas include aptamer-based assays, magnetic nanoparticle integration, and single-molecule studies of DNA packaging motors. Awards: Motorola PhD Fellowship (2001-2004) NSF U.S.-Japan Young Researchers Exchange (2007) #1 News in Analytical Chemistry (2007) #1 News in JACS Weekly (2007) Labs & Teams: The Savran Lab (savranlab.org) integrates engineering and biology to create next-generation biomedical devices. Research emphasizes translating nanotechnology into practical diagnostic tools for healthcare and environmental monitoring.