Donghao Lu is a Professor at Karolinska Institutet's Institute of Environmental Medicine, where he leads the Epidemiology of Women's Mental Health Lab. His research program focuses on psychiatric epidemiology with specialization in women's reproductive mental health, using large-scale population cohorts to investigate biological mechanisms and health outcomes. Primary research domains include: Risk factors and health consequences of perinatal depression and premenstrual disorders Bidirectional relationships between autoimmune diseases and mood disorders Gender disparities in mental health presentation and outcomes Cardiometabolic comorbidities in reproductive psychiatric conditions His recent publications (2023-2025) demonstrate strong methodological consistency, predominantly using Scandinavian national registries for longitudinal cohort designs. Research themes show progression toward understanding systemic health impacts of reproductive mood disorders, particularly cardiovascular risks and mortality. Over 90% of recent work incorporates population-level data analysis with sample sizes exceeding 10,000 participants. Laboratory focus includes integrating epidemiological methods with biomarker research to bridge obstetrics/gynecology and psychiatry. Current projects investigate inflammatory pathways in perinatal depression and genetic determinants of premenstrual disorder trajectories. The team maintains international collaborations across Scandinavia, China, and North America.






