- Molecular Imaging
- Inflammation
- Multimodal Imaging
- +۳ مورد دیگر
Prof. Dr. Michael Schäfers is a Full Professor of Technology and Imaging at the University of Münster and Head of the European Institute for Molecular Imaging (EIMI), operating within the Multiscale Imaging Centre (MIC). His research focuses on multimodal molecular imaging of inflammation using advanced in vivo methodologies across diverse disease models. His educational background includes: 1987-1994: Study of Medicine at the University of Münster 1994-1995: Postdoctoral research at MRC Cyclotron Unit, Imperial College School of Medicine, London 1995-1999: Postdoctoral work in Department of Nuclear Medicine, University Hospital Münster Schäfers' research centers on developing imaging techniques to visualize molecular and cellular dynamics in inflammation. His team identifies targets like matrix-metalloproteinases and S100A8/A9, develops high-affinity ligands labeled with radioactive isotopes or fluorescent dyes, and applies these in disease models including biopellet inflammation, autoimmune arthritis, and myocardial infarction using PET/CT, SPECT/CT, optical, and photoacoustic imaging systems. Analysis of his 2016-2018 publications reveals a strong focus on cardiovascular and neurological inflammation imaging. Key themes include MMP activity in atherosclerosis plaque phenotyping, leukocyte penetration in multiple sclerosis blood-brain barrier, CRISPR/Cas9-modified monocyte tracking, and novel probe development for MMP-13 inhibition, demonstrating integration of molecular biology with advanced imaging technologies. No specific scientific awards were mentioned, though Schäfers has held leadership roles as Coordinator of DFG CRC 656 'Cardiovascular Molecular Imaging' (2011) and Co-Coordinator of DFG Cluster of Excellence EXC 1003 'Cells in Motion' (2012). He supervises PhD students in interdisciplinary projects combining molecular imaging with immunology and genetics, supported by major DFG grants. His group provides comprehensive training in state-of-the-art imaging technologies and disease modeling approaches. The Schäfers lab comprises an interdisciplinary team with in-house chemistry capabilities for probe synthesis, operating high-resolution small animal PET/CT, SPECT/CT, optical, photoacoustic, and ultrasound systems alongside molecular biology and surgical facilities for integrated in vivo studies.


