- Genomics
- Epigenetics
- Gene Expression
- +۴ مورد دیگر
Guo-Cheng Yuan is a Senior Faculty member in the Department of Genetics and Genomic Sciences at the Icahn School of Medicine at Mount Sinai. His research focuses on genomics, epigenetics, and computational biology , with particular emphasis on single-cell analysis, chromatin regulation, and cancer immunology. Institution: Icahn School of Medicine at Mount Sinai School: Graduate School of Biomedical Sciences Department: Genetics and Genomic Sciences Research Interests Dr. Yuan's work spans multiple domains including: Single-cell RNA sequencing applications in brain development and cancer Chromatin structure analysis in differentiation processes Spatial transcriptomics for tissue microenvironment characterization Computational methods for multiomic data integration Enhancer-promoter interaction dynamics Development of robust bioinformatics pipelines Scientific Trends Analysis His recent publications (2021-2025) demonstrate a focus on single-cell and spatial omics methodologies applied to diverse biological contexts ranging from cancer immunology to neurodevelopment . Notable trends include: Development of trajectory analysis algorithms Multiomic integration for regulatory network mapping Epigenetic mechanisms in cell differentiation Computational approaches for data robustness Three-dimensional genome organization studies Applications in both developmental biology and oncology







