جستجوی استاد راهنمای دانشگاهی

Sunitha Nagrathمشاهده پروفایل

استاد

• Bio-MEMS and Microfluidics
• Nanotechnology
• Circulating Tumor Cells
• +۳ مورد دیگر

Sunitha Nagrath is a Professor of Chemical Engineering at the University of Michigan, leading the Nagrath Lab. Her research focuses on developing microfluidic and nanotechnology-based tools to isolate and analyze circulating tumor cells (CTCs) and extracellular vesicles (EVs) for cancer diagnostics and personalized medicine. She holds an AIMBE Fellowship and has pioneered technologies like the Graphene Oxide Chip and Microfluidic Labyrinth. Education PhD in Mechanical Engineering, Rensselaer Polytechnic Institute (2004) MS in Nuclear Engineering, Rensselaer Polytechnic Institute (2000) B.Tech in Chemical Engineering, Sri Venkateswara University (1992) Research Interests Her lab integrates engineering, biology, and clinical expertise to study CTCs' role in metastasis, develop high-throughput isolation methods, and leverage exosomes as liquid biopsy biomarkers. Key projects include: CTC-based monitoring of therapy response in lung and pancreatic cancers Microfluidic devices for simultaneous CTC and exosome analysis Functional studies of CTC-derived organoids for drug sensitivity testing Notable Achievements AIMBE Fellow (Junior Faculty, Harvard Medical School/MGH, 2008-2010) Over 150 peer-reviewed publications and patents on CTC/exosome technologies Recipient of the 2021-22 Chemical Engineering Staff Incentive Award (via lab member Mina Zeinali) Labs & Collaborations The Nagrath Lab collaborates with clinicians and engineers to translate technologies like the OncoBean Chip and EVOD chip into clinical settings. Current work emphasizes real-time CTC monitoring and exosome-based immuno-oncology strategies.

Christopher E. Nelsonمشاهده پروفایل

استادیار

• Gene therapy
• Regenerative medicine
• Genome editing
• +۷ مورد دیگر

Christopher E. Nelson is an Assistant Professor in the Department of Biomedical Engineering at the University of Arkansas, College of Engineering. His lab focuses on developing biologically inspired strategies for controlled drug and gene delivery, particularly in the context of gene therapy and regenerative medicine. He is actively supported by the NIH, DoD, and Arkansas Bioscience Institute. Education: Postdoctoral Fellow – Duke University Ph.D. – Vanderbilt University B.S. – University of Arkansas Research Focus: Dr. Nelson’s lab integrates genome editing technologies with targeted delivery systems to address challenges in treating genetic diseases and promoting tissue regeneration. Major themes include CRISPR/Cas9 delivery , gene regulation in wound healing , and safe-harbor genome integration in skeletal muscle. His work spans viral and non-viral delivery vehicles , including lipid nanoparticles and AAV vectors, with a strong emphasis on preclinical validation in models of Duchenne muscular dystrophy and inflammatory disease. Scientific Awards: Controlled Release Society Postdoctoral Fellowship The Hartwell Foundation Postdoctoral Fellowship NIH Pathway to Independence Award (K99/R00) Funding & Support: The Nelson Lab is currently funded by: NIH NIGMS R35 DoD CDMRP DMD IDEA Award Arkansas Bioscience Institute University of Arkansas Engineering & Honors Colleges Lab & Team: The Nelson Lab is a dynamic, interdisciplinary team working at the intersection of gene editing, biomaterials, and regenerative medicine. They regularly present at national conferences such as ASGCT and NCUR, and mentor undergraduate researchers through SURF and Honors College grants.

Matthew Lakinمشاهده پروفایل

دانشیار

• Molecular Computing
• DNA Nanotechnology
• Synthetic Biology
• +۷ مورد دیگر

Matthew Lakin is an Associate Professor with tenure in the Department of Computer Science at the University of New Mexico, with a courtesy appointment in the Department of Chemical & Biological Engineering. He is affiliated with the UNM Center for Biomedical Engineering and the School of Engineering, and collaborates extensively with the UNM Health Sciences Center and external institutions. Education: Ph.D., Computer Science, University of Cambridge, 2010 M.A. (Cantab), University of Cambridge, 2009 B.A. (Hons), Computer Science, University of Cambridge, 2005 Dr. Lakin's research focuses on molecular computing, DNA nanotechnology, synthetic biology, and formal verification of biomolecular circuits. He develops computational models and experimental systems for programmable biological devices, especially using heterochiral DNA to enhance stability in living cells. His work spans software tools for biodesign and experimental validation in mammalian systems, with applications in nanomedicine and biosensing. The recent publications highlight a strong trend in engineering robust, intelligent biomolecular systems. His work integrates machine learning concepts into chemical reaction networks, advances geometric modeling of DNA systems, and pioneers L-DNA-based circuits for intracellular applications. The research spans theoretical foundations, software tools, and wet-lab experimentation, emphasizing interdisciplinary innovation. Scientific Awards: Presidential Early Career Award for Scientists and Engineers (PECASE), 2025 NSF CAREER Award, 2021 UNM School of Engineering Junior Faculty Research Excellence Award, 2021 Multiple student awards under his mentorship, including the Outstanding Graduate Student Award and DNA28 Best Student Presentation recognition Dr. Lakin has advised numerous graduate and undergraduate students, including Ph.D. graduates in Biomedical Engineering and Computer Science. He leads major funded projects such as the NSF CAREER grant on heterochiral molecular computing, an EPSCoR Research Fellowship, and a $3M NSF grant on heavy metal biosensing in collaboration with Native American communities. He is also PI on multiple NSF grants related to synthetic cells and nucleic acid technologies. He directs the Lakin Lab for Programmable Biology, which operates within the Department of Computer Science and collaborates with Chemical & Biological Engineering and the Center for Biomedical Engineering. The lab emphasizes both computational modeling and experimental molecular biology, and runs an NSF-funded biotechnology summer camp in partnership with ¡Explora! science museum to strengthen STEM education in New Mexico.

Ian Bradleyمشاهده پروفایل

استادیار

• Environmental Engineering
• Water Treatment
• Wastewater Management
• +۳ مورد دیگر

Ian Bradley is an Assistant Professor in the Department of Civil, Structural and Environmental Engineering at the University at Buffalo, State University of New York. His research focuses on creating sustainable biological processes to address needs in engineered and natural systems for water and wastewater treatment and resource recovery. Education: PhD in Environmental Engineering, University of Illinois at Urbana-Champaign (2017) MS in Environmental Engineering, University of Illinois at Urbana-Champaign (2011) MS in Civil Engineering (Structures), University of Illinois at Urbana-Champaign (2010) Research Interests: Dr. Bradley specializes in microalgal-based nutrient recovery, wastewater surveillance for public health monitoring, PFAS degradation using nanomaterials, and sustainable resource recovery systems. His work integrates biological processes with environmental engineering to optimize wastewater treatment efficiency and develop predictive models for water quality and health outcomes. Publications: His recent research includes advancements in microalgal cultivation (EcoRecover process), wastewater-based epidemiology for SARS-CoV-2 tracking, and computational enzyme design for PFAS remediation. These studies demonstrate interdisciplinary expertise spanning environmental engineering, biotechnology, and public health analytics.

Jacques Archambaultمشاهده پروفایل

استاد

• Human Papillomavirus (HPV)
• Polyomavirus
• Viral DNA Replication
• +۴ مورد دیگر

Dr. Jacques Archambault is a Professor in the Department of Microbiology and Immunology at McGill University , and an associate member of the Division of Experimental Medicine since 2016. His research focuses on the molecular biology and pathogenesis of human papillomaviruses (HPVs) and polyomaviruses (HPyVs), with an emphasis on their replication mechanisms as episomes in host cells. The Archambault laboratory employs functional genomics, proteomics, and chemical biology approaches to identify cellular pathways exploited by these viruses and develop high-throughput assays for screening small molecule inhibitors of viral replication. Analysis of his recent publications reveals a strong focus on HPV and HPyV replication machinery, including studies on the E1 helicase, UAF1-USP1 interactions, and structural characterization of viral proteins involved in DNA replication. His work bridges virology, oncology, and drug discovery, particularly targeting oncogenic HPV types implicated in anogenital and oropharyngeal cancers, as well as HPyVs like BKPyV and JCPyV that cause pathologies in immunosuppressed patients. Current efforts in the lab aim to elucidate the molecular mechanisms by which HPVs and HPyVs replicate their genomes and to develop antiviral therapies targeting these processes. Techniques such as fluorescence anisotropy, NMR spectroscopy, and crystallography are frequently employed to study protein-DNA and protein-protein interactions critical to viral replication.

Ralph Bockمشاهده پروفایل

استاد

• Plant Molecular Biology
• Chloroplast Biology
• Organelle Biotechnology
• +۷ مورد دیگر

Prof. Dr. Ralph Bock serves as Director of Department 3: Organelle Biology, Biotechnology and Molecular Ecophysiology at the Max Planck Institute of Molecular Plant Physiology in Potsdam, Germany, where he also leads the Organelle Biology and Biotechnology research group. Previously, he held positions as C4 Professor for Plant Biochemistry and Biotechnology at the University of Münster (2001-2004) and Group Leader at the Institute of Biology III, University of Freiburg (1996-2001). His academic credentials include: Habilitation: University of Freiburg, 1999 Doctorate: University of Freiburg, 1996 Diploma: University of Halle, 1993 Prof. Bock's research focuses on plant molecular biology with particular emphasis on chloroplast biology, organelle biotechnology, and molecular ecophysiology. His work spans genetic engineering of plastids, photosynthesis research, plant biotechnology applications, and understanding organelle-nucleus communication. He has made significant contributions to developing chloroplast transformation systems and applying them to molecular farming, metabolic engineering, and understanding fundamental processes in plant cell biology. His research has important implications for sustainable agriculture, bioenergy, and pharmaceutical production, particularly through the development of plant-based systems for producing vaccines and therapeutic proteins. Analysis of Prof. Bock's recent publications (2023-2025) reveals a strong focus on chloroplast biology, genetic engineering, and molecular farming applications. His work spans fundamental research on organelle genetics, photosynthesis, and stress responses, as well as applied research on using plant and algal systems for biopharmaceutical production. A notable trend is the increasing use of advanced genetic engineering techniques, including CRISPR-based approaches, to manipulate organelle genomes. His research also shows growing interest in algal systems as alternative expression platforms for molecular farming, particularly red algae like Porphyridium for producing viral antigens and glycoproteins.

Jeff S Abramsonمشاهده پروفایل

استاد

• Membrane Transport Proteins
• Structural Biology
• Sugar Transporters
• +۵ مورد دیگر

Jeff S Abramson is a Professor of Physiology in the David Geffen School of Medicine at the University of California Los Angeles (UCLA). His research focuses on the structural and functional characterization of membrane transport proteins, particularly sugar transporters and mitochondrial channels. He maintains an active laboratory investigating the molecular mechanisms of cellular transport processes. Dr. Abramson's primary research interests center on membrane transport proteins, with particular emphasis on sugar symporters and voltage-dependent anion channels (VDACs). His work combines structural biology, biophysics, and biochemistry to understand the molecular mechanisms of transport, including conformational changes during transport cycles, substrate recognition, and regulation by membrane potential. His research has significant implications for understanding metabolic disorders, mitochondrial function, and potential therapeutic targets. Analysis of Dr. Abramson's publication record reveals a consistent focus on membrane protein structure-function relationships over the past two decades. His work demonstrates expertise in X-ray crystallography, cryo-electron microscopy, and functional assays to characterize transport proteins. Recent publications show increasing emphasis on mitochondrial biology, particularly VDAC structure and function, while maintaining his longstanding interest in sugar transport mechanisms. His research bridges fundamental biophysical principles with potential biomedical applications in metabolic diseases. Dr. Abramson has been awarded multiple NIH grants supporting his research, including the R35GM135175 grant titled 'Deciphering molecular details of cellular sugar transport and their roles in disease' (2020-2024), R01GM124783 'Functional and structural studies of unique pathogenic transporters involved in glycobiology' (2017-2021), and R01GM078844 'Structural and functional characterization of sugar transporters in health and disease' (2006-2020). As Principal Investigator, Dr. Abramson has mentored numerous graduate students and postdoctoral researchers. His laboratory has made significant contributions to understanding the structure-function relationships of membrane transport proteins through collaborations with researchers across multiple disciplines. The lab utilizes advanced techniques including X-ray crystallography, cryo-EM, electrophysiology, and computational modeling to address fundamental questions about membrane protein mechanisms. Dr. Abramson's laboratory is part of UCLA's broader research ecosystem focused on structural biology and membrane protein research. His work intersects with several research centers at UCLA including those focused on metabolic diseases and structural biology. The lab maintains active collaborations with researchers specializing in biophysics, computational modeling, and disease mechanisms to translate basic findings into potential biomedical applications.

Sven Pankeمشاهده پروفایل

استاد

• Bioprocess Engineering
• Synthetic Biology
• Fermentation Technology
• +۳ مورد دیگر

Prof. Dr. Sven Panke is a Full Professor and Head of the Department of Biosystems Science and Engineering at ETH Zürich. His research focuses on bioprocess engineering, synthetic biology, and enzymatic process development. Key areas include miniaturized bioreactor systems, microbial engineering for novel metabolite production, and high-throughput screening methodologies. Education: Studied Biotechnology at TU Braunschweig, with postgraduate research at the German National Research Center for Biotechnology and ETH Zurich. Transitioned from industry (DSM) to academia in 2001 as an Assistant Professor, progressing to Associate Professor (2007-2009) before leading the BSS department. Research interests emphasize directed evolution of enzymes, metabolic pathway engineering, and systems biology approaches to optimize microbial production systems. Current projects include bio-indigo synthesis, antimicrobial peptide discovery, and synthetic biology tools for cellular engineering. Labs/Teams: Leads the Bioprocess Engineering Lab at ETH Zurich, collaborating on projects like the E. coli import system design and γ-glutamyltransferase engineering. Active in developing microfluidics platforms for parallel reaction analysis. Grants/Advising: Funded by initiatives in sustainable biomanufacturing and synthetic biology. Supervises graduate students in bioprocess design and microbial systems engineering.

David Latulippeمشاهده پروفایل

استاد

• Membrane Science
• Bioprocessing
• DNA Purification
• +۴ مورد دیگر

David Latulippe is a Professor in the Department of Chemical Engineering at McMaster University. He joined McMaster in 2012 after postdoctoral work at Cornell University and a PhD at Penn State University, focusing on membrane filtration for DNA purification. His industrial experience includes roles at ZENON Environmental (now GE Water) in hollow-fiber membrane design for water treatment. Research interests include Membrane science and technology Bioprocessing of therapeutic viruses Microscale systems for biological applications Environmental engineering solutions for water treatment Current projects involve collaborations with industry partners like Ceapro and Aevitas, and the development of a biomanufacturing automation lab with Sartorius. Recent publications highlight advancements in Nanofiltration and microfiltration for viral vectors Conductive membranes for electrochemical applications Microfluidic systems for DNA analysis Environmental monitoring of biocides and microplastics Scientific recognition includes the Young Membrane Scientist Award (2014). Teaching activities focus on Fluid Mechanics (CHEMENG 2O04) and Industrial Separation Processes (CHEMENG 4M03).

• Biotechnology
• Systems Engineering in Bioprocessing
• Model-Based Tools
• +۴ مورد دیگر

Professor Cleo Kontoravdi is a Professor of Biological Systems Engineering at the Department of Chemical Engineering, Imperial College London, within the Faculty of Engineering. Her roles include Director of Postgraduate Studies (2021–present) and Postgraduate Admissions Tutor (2018–2021). She holds affiliations with key research centers such as the Centre for Process Systems Engineering, Centre for Synthetic Biology, and Future Vaccine Manufacturing Research Hub. Her research focuses on applying systems engineering principles to bioprocessing, integrating model-based tools like sensitivity analysis and optimization with experimental work on mammalian cell cultures and vaccine production. Key areas include metabolic flux analysis, media optimization, and multiscale modeling. Her recent publications highlight advancements in hybrid modeling frameworks, mRNA vaccine process design, and metabolic engineering of CHO cells. She actively contributes to vaccine manufacturing strategies and sustainable biopharmaceutical supply chains. Education: PhD (2007) and MEng (2002) in Chemical Engineering from Imperial College London. Professional experience spans academic roles (since 2007) and industry R&D at Lonza Biologics (2006–2007). Her work bridges computational biology, bioprocess engineering, and systems biology, addressing challenges in vaccine development and production efficiency. Awards: Not explicitly listed in the provided text. Research grants and collaborations are implied through her involvement in high-impact projects like the Future Vaccine Manufacturing Hub. She advises on bioprocess optimization, glycoengineering, and biomanufacturing sustainability.

Maureen Dolanمشاهده پروفایل

دانشیار

• Plant Molecular Biology
• Aquaculture Health
• Biotechnology
• +۷ مورد دیگر

Dr. Maureen Dolan is an Associate Professor of Molecular Biology and Director of the Biotechnology Program at Arkansas State University's Beck College of Sciences & Mathematics, Department of Molecular Biosciences. She holds a PhD in Biochemistry and Molecular Biology from the University of Florida. Research Focus: Dr. Dolan develops plant-based bioproduction systems for therapeutic proteins targeting immune health in aquaculture. Her work includes optimizing RNA extraction protocols, engineering glycopeptide tags for protein stability, and creating molecular diagnostics for agricultural and food industries. Publication Trends: Recent articles focus on rhizosphere metatranscriptomics, hydroxyproline-O-glycosylation techniques, and plant-based cytokine production for aquatic and poultry health. Her work spans plant molecular biology, biotechnology, and cross-species therapeutic applications. Contact: Office located at Arkansas Biosciences Institute, Room 311 and Lab Science East, Room 202. Email: mdolan@AState.edu.

• Machine Learning
• Statistical Computing
• Cluster Analysis
• +۲ مورد دیگر

Theresa Scharl-Hirsch is a Senior Scientist and Deputy Scientific Director at the Core Facility Bioinformatics, University of Natural Resources and Life Sciences, Vienna (BOKU). She holds concurrent appointments at the Institute of Statistics, BOKU, and has extensive experience in bioprocess modeling, machine learning, and statistical computing. Her work bridges biochemical engineering with advanced data science methodologies. Her research focuses on real-time monitoring of biopharmaceutical processes, clustering of high-dimensional data (particularly RNA sequencing), and application of explainable machine learning techniques. She has developed statistical models for process optimization and quality prediction in antibody capture and protein purification, with a strong emphasis on industrial implementations using R programming. Key trends in her publications include three-way data analysis, matrix-variate Gaussian mixture models, and permutation-based variable importance methods for deep learning architectures. Her work spans bioprocess engineering, bioinformatics, and industrial data science applications.

• Biotechnology
• Bioplastics
• Biocompatibility
• +۳ مورد دیگر

Manfred Zinn serves as a Professor at the University of Applied Sciences and Arts Western Switzerland (HES-SO), specifically within the School of Chemistry and Life Sciences. He leads the Biotechnology and Sustainable Chemistry research group at the Life Science Engineering department in Sion, Switzerland. His academic position includes significant research leadership responsibilities and active contributions to the field of bioplastics and sustainable materials. Professor Zinn's research focuses primarily on biotechnology applications for sustainable materials, with particular expertise in polyhydroxyalkanoates (PHAs) and other bioplastics. His work spans microbial biosynthesis, material characterization, and industrial applications of biodegradable polymers. He investigates the metabolic pathways of PHA-producing microorganisms, develops novel analytical methods for biopolymer characterization, and explores practical applications of bioplastics in medical and industrial contexts. His research integrates microbiology, polymer chemistry, and process engineering to address challenges in sustainable materials development. Analysis of his recent publications (2019-2024) reveals a strong focus on advancing the science and technology of bioplastics, particularly polyhydroxyalkanoates. His work addresses key challenges in monomer composition control, polymer characterization, biosynthesis optimization, and industrial applications. A significant trend in his research involves developing sophisticated analytical methods for biopolymer production monitoring and exploring novel applications for biodegradable materials in medical and industrial contexts. His collaborative work spans multiple countries and institutions, reflecting the international nature of bioplastics research. Professor Zinn has secured significant research funding through multiple competitive grants, including Innosuisse and Swiss National Science Foundation projects. His research portfolio includes projects on biosynthesis of Chlorella, electroplating processes for biodegradable materials, and online flow cytometry analysis for microbial bioplastic production. These projects demonstrate his ability to secure funding for interdisciplinary research at the intersection of biotechnology, materials science, and sustainable chemistry. His collaborations extend to institutions including the Frauenhofer Institute and Chulalongkorn University in Bangkok. The Biotechnology and Sustainable Chemistry research group led by Professor Zinn maintains strong laboratory facilities for microbial cultivation, biopolymer synthesis and characterization. The group utilizes advanced equipment including bioreactors, flow cytometry systems, and polymer analysis instrumentation. Their research bridges fundamental science with practical applications, focusing on developing sustainable alternatives to conventional plastics while addressing technical challenges in production, characterization, and implementation.

• DNA Repair Mechanisms
• Genetics
• Pharmacology
• +۷ مورد دیگر

Colin R Campbell is an Associate Professor in the Department of Pharmacology at the University of Minnesota Medical School . His research focuses on DNA repair mechanisms , particularly DNA-protein crosslink repair , homologous recombination , and mitochondrial DNA stability , with significant contributions to understanding cancer mechanisms and genetic toxicology . Research Themes DNA-Protein Crosslink Repair Homologous Recombination Pathways Mitochondrial DNA Maintenance Chemotherapy-Induced DNA Damage Enzymatic Processing Mechanisms Article Trends 2024-2025 work emphasizes transcription-coupled DNA repair and ubiquitin-mediated repair pathways 2020-2023 studies explore mitochondrial crosslink repair and interdisciplinary sustainability leadership 2000-2018 publications cover rad51 interactions , nitrogen mustard effects , and calpain-mediated repair enzyme degradation Grants & Projects NIH/NHLBI: Summer Research (2024-2029) NIH/NIEHS: DNA-Protein Crosslink Repair (2019-2025) NIH/NHLBI: Cellular Repair Mechanisms (2018-2024) Collaborations Natalia Tretyakova (Chemistry) Hoang D Nguyen (Microbiology) Paul B Bitterman (Medicine) Beverly S Moriarity (Genetics)

Trudy Morrisonمشاهده پروفایل

استاد

• Paramyxovirus
• Pneumovirus
• Respiratory Syncytial Virus (RSV)
• +۸ مورد دیگر

Trudy Morrison is a Professor in the Department of Microbiology at UMass Chan Medical School and a key figure in the T.H. Chan School of Medicine. Her research focuses on paramyxovirus and pneumovirus mechanisms, particularly membrane fusion and assembly processes for vaccine development. She has contributed extensively to understanding Newcastle disease virus and respiratory syncytial virus (RSV) glycoprotein interactions, leading to innovative virus-like particle (VLP) vaccine candidates. Education: BA in Biology, Wellesley College PhD in Microbiology/Molecular Biology, Tufts University School of Medicine Postdoctoral training at Massachusetts Institute of Technology Morrison's work spans molecular virology, vaccine design, and immunological profiling. She has pioneered studies on the role of RSV F protein conformation in VLPs for neutralizing antibody induction and explored maternal immunization models. Recent projects include SARS-CoV-2 VLP vaccines and cross-species immune responses. Her laboratory is renowned for characterizing paramyxovirus assembly requirements and lipid raft dependencies. Awards include 2011 AAAS Fellowship, 2014 American Academy of Microbiology Fellowship, and multiple institutional teaching honors. Scientific Awards: 2011 AAAS Fellow 2014 American Academy of Microbiology Fellow 2020-2021 Lamar Soutter Award 2003 Sara Stone Excellence in Education 2006 Faculty Achievement Award