جست‌وجوی استاد و پژوهشگر

• Molecular Biology
• Transcription
• RNA Biology
• +۳ مورد دیگر

David Lopez Martinez is a Researcher in the Department of Cellular and Molecular Medicine at the University of Copenhagen's Faculty of Health and Medical Sciences. He works within the Transcription, RNA, and Gene Medicine Program as part of the Svejstrup Group, focusing on molecular mechanisms of transcription and its interface with DNA-related processes. His research spans RNA biology, transcription mechanisms, and DNA repair pathways. Key areas include RNA polymerase II function, transcription termination, DNA damage response pathways, and the Fanconi anemia pathway. His work bridges fundamental molecular processes with potential implications for human health and disease. Dr. Martinez has published significant papers in high-impact journals including Molecular Cell, Journal of Molecular Biology, and Cell Reports. His recent publications (2023-2025) demonstrate expertise in RNA Polymerase II termination mechanisms, PAF1C-mediated kinase activation, and regulation of DNA repair complexes. He maintains active collaborations across multiple institutions, contributing to our understanding of essential cellular processes. His research has garnered attention in the scientific community with multiple citations and downloads of his publications.

Paul Kempenمشاهده پروفایل

دانشیار

• Nanotechnology
• Drug Delivery Systems
• Biomedical Engineering
• +۳ مورد دیگر

Paul Kempen is an Associate Professor at the Technical University of Denmark (DTU), affiliated with the Department of Health Technology and the National Centre for Nano Fabrication and Characterization. His research focuses on nanotechnology applications in drug delivery, biomedical engineering, and materials science, with a particular emphasis on liposomes, gold nanoparticles, and nanozymes. He supervises multiple PhD students and has contributed over 60 peer-reviewed publications. His research interests span the development of nanocarriers for targeted drug delivery, characterization of biomaterials, and the design of sustainable nanotechnologies. Collaborations include studies on phycosphere microbiomes, ammonia electrosynthesis, and MRI tattoo interactions. He leads projects such as 'R2R ProBac' and 'Nanofluidic Electron Diffraction,' exploring biofilm formation and advanced microscopy techniques. Key achievements include the creation of cost-effective wound dressings using nanogels and advancements in mRNA lipid nanoparticle delivery via gastrointestinal devices. His work aligns with UN Sustainable Development Goals, particularly in affordable and clean energy and good health and well-being. Paul advises PhD students in nanofluidics, polymer surface engineering, and electron microscopy applications. His lab, Nanolab , specializes in nanocharacterization and fabrication. Future directions include expanding nanomedicine applications and sustainable nanomaterials.

Barbara Guerraمشاهده پروفایل

دانشیار

• Protein Kinases
• Cancer Biology
• Cell Signaling
• +۷ مورد دیگر

Barbara Guerra is an Associate Professor in the Department of Biochemistry and Molecular Biology at the University of Southern Denmark, Faculty of Science. She leads the Barbara Guerra Lab, which is part of the Translational Biology research section, focusing on the role of protein kinases in human disease, particularly cancer. She also serves as Head of the PhD School at the Faculty of Science since 2020, demonstrating strong leadership in academic training and research supervision. Her research expertise lies in protein kinase CK2, a key regulator of cell survival, growth, and differentiation. Her laboratory investigates CK2-mediated signaling pathways in cancer, DNA damage response, lipid metabolism, and cell cycle regulation. She has contributed extensively to understanding CK2's role in oncogenesis and its potential as a therapeutic target. Her recent publications reveal a consistent focus on CK2 in cancer metabolism, hypoxia signaling (e.g., HIF-1α), autophagy, and the development of kinase inhibitors. Themes include pharmacological targeting of CK2, regulation of metabolic enzymes like SCD-1, and modulation of tumor suppressors such as p27KIP1. She frequently collaborates on interdisciplinary studies involving drug delivery systems and natural product-based inhibitors. Barbara Guerra has received recognition for her teaching excellence, including a Faculty of Natural Science teaching prize in 2006. She serves on the editorial boards of Oncology Reports and Pharmaceuticals , contributing to scientific peer review and dissemination. She has supervised over 100 undergraduate, Master’s, and PhD students, as well as six postdoctoral researchers, indicating a strong commitment to mentoring the next generation of scientists. Her research is supported by numerous projects and she plays a central role in PhD education at the university level. Her lab is actively involved in translational research, bridging basic molecular mechanisms with potential clinical applications in oncology and metabolic disorders.

Kristian Almstrupمشاهده پروفایل

دانشیار

• Genetics
• Epigenetics
• Reproduction
• +۹ مورد دیگر

Kristian Almstrup serves as Associate Professor at the Department of Cellular and Molecular Medicine, Faculty of Health and Medical Sciences, University of Copenhagen, and holds a Senior Scientist position at the Department of Growth and Reproduction, Copenhagen University Hospital - Rigshospitalet. His dual appointment bridges clinical practice and academic research in reproductive genetics. Dr. Almstrup's research primarily focuses on the intersection of genetic and epigenetic variation with reproductive endpoints, testicular gene expression, and sperm cell function. His work has pioneered understanding of piRNAs in human spermatogenesis, genetic variants causing non-obstructive azoospermia, and genetic factors associated with testicular germ cell cancer. His group employs cutting-edge techniques including single-cell/nuclei methods and spatial transcriptomics to study the complex cellular composition of testicular tissue. Analysis of Almstrup's 15 most recent publications reveals a consistent focus on male reproductive genetics, with particular emphasis on non-coding RNAs (especially piRNAs), genetic determinants of spermatogenic failure, and environmental factors in declining fertility. His research spans from basic molecular mechanisms to clinical applications, with several publications in high-impact journals including Nature, Nature Communications, and the New England Journal of Medicine. Dr. Almstrup actively contributes to medical education through teaching in the Medical Genetics course for Medicine and Molecular Biomedicine students, as well as organizing PhD courses in Genetics of Reproduction. His editorial work includes serving as Editor for Andrology, Scientific Reports, and Frontiers in Cell and Developmental Biology. The Almstrup Group, based at Rigshospitalet, maintains an active research program with current team members including Nina Mørup Nygaard, Sofia B. Winge, Gülizar Saritas, Ailsa Maria Main, and Maria Lykkegaard Nicolaisen. The group participates in several international consortia including GEMINI, IMiGC, and TECAC, focusing on male infertility and testicular cancer genetics.

Leon Eyrich Jessenمشاهده پروفایل

دانشیار

• Bioinformatics
• Immunology
• Machine Learning
• +۶ مورد دیگر

Leon Eyrich Jessen is an Associate Professor and Groupleader at the Department of Health Technology, Technical University of Denmark (DTU). He leads the Computational Autoimmunity research group, focusing on computational immunology with a particular emphasis on understanding disruptions in central tolerance and the mechanisms that allow the immune system to differentiate between self and non-self. His work aims to uncover immuno-cellular processes associated with autoimmune diseases through single-cell technology and machine learning-based bioinformatics tools. Dr. Jessen's research spans several key areas including Bioinformatics, Immunology, Machine Learning/AI, Data Science, and T-cell Biology. His work specifically addresses Computational Autoimmunity, Bayesian Modeling, and Molecular Evolution. He employs single-cell technology to investigate autoimmune disease mechanisms, with applications in psoriatic arthritis, diabetes, and other autoimmune conditions. His group develops computational methods for T cell receptor analysis, epitope prediction, and spatial transcriptomics. His recent publications demonstrate a strong focus on computational immunology, with key contributions in single-cell RNA sequencing, T cell receptor analysis, and spatial transcriptomics. His work bridges computational methods with immunological applications, particularly in autoimmune disease research. The research shows a consistent pattern of developing and applying machine learning algorithms to complex immunological data, with significant contributions to understanding T cell biology and autoimmune mechanisms. Dr. Jessen actively supervises PhD students including Drachmann, C., Montemurro, A., Povlsen, H. R., and Schaap-Johansen, A.-L. on projects related to single-cell analysis, immunoinformatics, and deep learning methods for immunotherapy. He is also the creator and instructor of "R for Bio Data Science," which is the third largest course at his department, demonstrating his commitment to education and training the next generation of bioinformaticians. He leads the Computational Autoimmunity group which focuses on developing, applying, and serving machine learning-based bioinformatics tools. The group works at the intersection of computational methods and immunological research, with particular emphasis on single-cell technologies and their application to autoimmune disease mechanisms.

Henriette Skovgaard Andersenمشاهده پروفایل

پژوهشگر

• Molecular Biology
• Biochemistry
• RNA Splicing
• +۳ مورد دیگر

Henriette Skovgaard Andersen is a researcher at the Department of Biochemistry and Molecular Biology, University of Southern Denmark. Her work focuses on molecular biology, genetics, and RNA splicing mechanisms, particularly in neurodegenerative diseases like spinal muscular atrophy and Costello syndrome. She utilizes advanced sequencing technologies and oligonucleotide-based therapies to explore gene regulation and splicing defects. Her research spans translational medicine, with a focus on: RNA splicing regulation in genetic disorders Development of splicing-correcting therapeutics Neurodegenerative disease mechanisms Recent publications highlight her expertise in SMN2/SMN1 gene interactions, HRAS mutations, and resveratrol's role in metabolic disorders. Collaborations include international conferences and workshops on sequencing technologies and presentation techniques. She contributes to peer-reviewed journals and is involved in academic workshops, demonstrating active participation in research networks and educational events.

• Endocrinology
• Diabetes Research
• Gut Hormones
• +۳ مورد دیگر

Asger Bach Lund serves as a Clinical Associate Professor in the Department of Clinical Medicine at the University of Copenhagen's Faculty of Health and Medical Sciences. His institutional address is Blegdamsvej 3, 2200 Copenhagen N, Denmark, affiliated with Region Hovedstaden (Region H) healthcare system. Dr. Lund's research focuses on endocrine physiology with specialization in gut-derived hormones, particularly proglucagon-derived peptides (GLP-1, GIP, GLP-2), their roles in metabolic regulation, and therapeutic applications for diabetes and obesity. His work investigates intestinal hormone expression patterns, amino acid-stimulated secretion dynamics, and molecular mechanisms underlying bariatric surgery outcomes. Analysis of his recent publications reveals dominant research trends in mucosal transcriptomics, pancreatic alpha cell function, and gut-bone axis interactions. His studies frequently employ human physiological models, translational mouse-human comparisons, and advanced molecular techniques to explore metabolic pathways. Lund maintains extensive collaborative networks within Copenhagen's endocrine research community, particularly with the Knop and Holst research groups. His work appears in high-impact journals including Cell Reports Medicine , Gut , and Physiological Reviews , demonstrating significant contributions to metabolic disease research.

• Virology
• RNA Biology
• MicroRNA Research
• +۵ مورد دیگر

Nicolas Julien Fossat serves as an Associate Professor in the Department of Immunology and Microbiology at the Faculty of Health and Medical Sciences, University of Copenhagen. His research spans virology, RNA biology, and developmental biology with a particular focus on viral-host interactions and molecular mechanisms of disease. His research interests primarily focus on RNA biology and virology, with significant contributions to understanding viral RNA modifications, microRNA interactions in viral infections, and the molecular mechanisms of viral replication. His work on Hepatitis C virus RNA capping with flavin adenine dinucleotide represents a major discovery in the field of virology. Additionally, his research extends to developmental biology, particularly in understanding transcription factor networks like TWIST1 in cell differentiation processes. Analysis of his recent publications reveals a strong emphasis on RNA-virus interactions, particularly with flaviviruses including Hepatitis C, yellow fever, and tick-borne encephalitis viruses. His work on SARS-CoV-2 microRNA interactomes during the pandemic demonstrates his ability to pivot research toward emerging health threats. His publications in high-impact journals including Nature, Nature Communications, and Cell Reports highlight the significance of his contributions to the field. Fossat has established productive collaborations with prominent researchers including Bukh, Scheel, and Ramirez, resulting in multiple high-impact publications. His work has received substantial attention, with several papers being highlighted in news outlets and social media platforms, indicating the broader impact of his research.

Kerstin Skovgaardمشاهده پروفایل

عضو هیئت علمی

• Antiviral Immunology
• Zoonotic Influenza
• Translational Research
• +۹ مورد دیگر

Kerstin Skovgaard is a Senior Researcher at the Department of Biotechnology and Biomedicine , Technical University of Denmark . Her work focuses on antiviral immunology with emphasis on zoonotic influenza viruses and metabolic syndrome's impact on infection severity . She develops translational animal models for innate immune research in respiratory infections and post-traumatic conditions . Research Interests Antiviral Immunology of influenza A viruses and PEDV Metabolic Syndrome and obesity-related immunity Translational models for respiratory diseases and gut-brain axis miRNA profiling in equine osteoarthritis and porcine infections Immunomodulatory diets with algae and probiotics Biomarker discovery through proteomics and RT-qPCR Scientific Contributions include 202+ publications across influenza , gut immunity , and joint inflammation . Her recent 15 articles demonstrate expertise in porcine models for human diseases , with emphasis on innate immune responses , miRNA dynamics , and metabolic-immune interactions . Supervision includes PhD students : J. Pina Agullet B. L. Henriksen C. J. M. Polhaus H. A. Laybourn C. López-Figueroa Methodologies encompass microfluidic qPCR , RNA-Seq , and advanced in vitro systems . Her research supports UN Sustainable Development Goals through cost-efficient diagnostics and therapeutic development .

Kristoffer Vitting-Seerupمشاهده پروفایل

دانشیار

• Bioinformatics
• Computational Biology
• Transcriptomics
• +۵ مورد دیگر

Kristoffer Vitting-Seerup is an Associate Professor at the Department of Health Technology , Technical University of Denmark, specializing in Bioinformatics and Isoform Analysis . His research focuses on leveraging RNA sequencing, alternative splicing, and protein domain variants to advance cancer genomics and neuro-oncology. Current academic rank: Associate Professor Key collaborations: DTU, University of Copenhagen, international cancer research teams Supervisory role: 5 PhD students in projects spanning machine learning for single-cell sequencing and isoform-level systems biology His work demonstrates strong emphasis on transcriptomics in glioblastoma, with recent publications analyzing tumor infiltration, neurodevelopmental pathways, and therapy resistance mechanisms. Articles reveal expertise in alternative splicing's role in biological signaling, protein domain functional diversity, and genomic stability in cancer stem cells. Research tools developed include satuRn for transcript usage analysis and IsoformSwitchAnalyzeR for splicing variant characterization. Current projects aim to improve clinical diagnostics through machine learning frameworks and enhance understanding of isoform-level biology in diseases. Advising: Rasmussen, M. N. (PhD Student, 2025-2028) Zhen, Z. T. (PhD Student, 2024-2027) Hsieh, C.-Y. (PhD Student, 2024-2027) Kanakoglou, D. S. (PhD Student, 2023-2026) Dam, S. H. (PhD Student, 2021-2025)

• Gene regulation
• Bioinformatics
• RNA Biology
• +۶ مورد دیگر

Albin Gustav Sandelin is a Professor in the Department of Biology at the University of Copenhagen, specializing in bioinformatics and RNA biology. With a PhD in Functional Genomics from Karolinska Institute (2004) and an MSc in Molecular Biology from Stockholm University (2000), his career spans roles at institutions including RIKEN Yokohama Institute and Tokyo Medical and Dental University. His research focuses on Gene regulation mechanisms Transcription start site dynamics RNA sequencing methodologies Promoter architecture analysis Cancer microenvironment interactions . Recent publications highlight his work in pancreatic cancer adaptation to acidic environments (2024-2025), TLDR-seq for RNA analysis, and JASPAR database development. He supervises PhD students including Eivind Valen and Eric Man-Hung, with a history of teaching bioinformatics courses at Karolinska Institute and Copenhagen University. Key collaborations involve institutions in Japan, Canada, and Sweden, with ongoing contributions to open-access genomic resources like JASPAR.

Anja Grothمشاهده پروفایل

استاد

• Molecular Cell Biology
• Epigenetics
• DNA Repair
• +۳ مورد دیگر

Anja Groth, 43 years old, is a full professor at the Biotech Research and Innovation Centre (BRIC) under the University of Copenhagen's Faculty of Health Sciences. Her research centers on molecular cell biology, epigenetics, DNA repair, and genome stability, with significant contributions to understanding how cells maintain functional memory during division—a critical process for both human development and cancer progression. Education: MSc in Biochemistry, University of Copenhagen PhD in Cancer Biology, University of Copenhagen (2004) Postdoc at Institut Curie, Paris (3 years) Her groundbreaking work on DNA repair mechanisms revealed a protein critical for cancer cell survival through error-free DNA repair. This discovery is paving the way for novel cancer therapies that block this protein. Using advanced molecular biology and interdisciplinary collaboration, she has published in top journals like Nature and secured two major ERC grants. Key Research Themes: Epigenetic memory and chromatin replication DNA damage repair pathways Histone dynamics and inheritance Replication fork stability Protein networks in genome maintenance Articles show a consistent focus on histone chaperones, ubiquitination pathways, and chromatin assembly factors. Her 2016 discovery of H4K20me0 marks and the TONSL–MMS22L complex has had lasting impacts on DNA repair research. Awards & Grants: EliteForsk Award (2018) EMBO Investigator Heirloom Award for Women Scientist Leaders ERC Starting Grant ERC Consolidator Grant As leader of a diverse research group of 15 international scientists (primarily women), Groth emphasizes collaborative innovation and trust-building in scientific environments. She advocates for sustainable lab practices and flexible research strategies that allow unexpected discoveries.

Brage Storstein Andresenمشاهده پروفایل

استاد

• Molecular Genetics
• RNA Splicing
• Genetic Diseases
• +۷ مورد دیگر

Brage Storstein Andresen is a Professor in Translational Biology at the Department of Biochemistry and Molecular Biology, University of Southern Denmark. His research focuses on molecular genetics, RNA splicing mechanisms, and genetic diseases, particularly in the areas of metabolic disorders and enzyme deficiencies. His research interests center on understanding how genetic mutations affect RNA splicing and contribute to disease, with particular expertise in exon vulnerability, pseudoexon activation, and developing RNA-based therapies. His work bridges fundamental molecular biology with clinical applications, especially in newborn screening and metabolic disorders like propionic acidemia and medium-chain acyl-CoA dehydrogenase deficiency. Analysis of his recent publications reveals a strong focus on RNA splicing mechanisms, with increasing emphasis on therapeutic applications. His research combines molecular biology, biochemistry, and genetic engineering approaches, particularly CRISPR technology and splice-switching oligonucleotides, to develop treatments for genetic disorders. A significant portion of his work addresses metabolic diseases and cancer-related pathways involving protein kinase CK2. Active participant in multiple research projects through 2026 Editor of research journal Membership in scientific committees Professor Andresen has delivered numerous presentations on genetic splicing mechanisms and their disease implications, including the notable talk 'WHEN THE GENETIC CODE IS NOT ENOUGH: How single nucleotide changes can affect pre-mRNA splicing and cause disease.' His research has attracted significant media attention, with coverage in multiple news outlets and social media platforms.

Charlotte Held Gotfredsenمشاهده پروفایل

استاد

• Organic Chemistry
• Natural Products Chemistry
• Microbial Secondary Metabolism
• +۴ مورد دیگر

Charlotte Held Gotfredsen is a Professor in the Department of Chemistry at the Technical University of Denmark (DTU). Her research focuses on microbial secondary metabolites, organic chemistry, and metabolomics. She leads the Center for Microbial Secondary Metabolites and is affiliated with DTU Microbes Initiative. Her work contributes to Sustainable Development Goals related to health and innovation. Research interests include natural product discovery, biosynthesis of antibiotics, and development of analytical tools like NMR-based metabolomics. She supervises multiple PhD projects, including studies on endoribonuclease recruiters, bacterial secondary metabolites, and fragment-based drug discovery targeting nucleotide and TNF receptors. Publications span antifungal compounds from Streptomyces, enzymatic fluorination, and genome-driven discovery of bioactive metabolites. Her lab employs cutting-edge techniques in synthetic biology and chemical biology, with a focus on drug discovery and metabolic engineering. Current projects include optimizing metabolomic experiments and expanding biocatalytic methods for fluorine chemistry. She collaborates internationally on topics like RNA-targeted drug design and Alzheimer’s biomarkers.

• Epigenetics
• Transcriptional Regulation
• Cancer Research
• +۳ مورد دیگر

Simon Toftholm Jakobsen is a Postdoctoral Researcher in the Department of Biochemistry and Molecular Biology at the University of Southern Denmark, specializing in Functional Genomic Studies and Metabolism. His research focuses on epigenetic mechanisms and transcriptional regulation with significant implications for cancer biology. Dr. Jakobsen's research spans several interconnected domains: Epigenetic regulation of gene expression Transcriptional enhancer and promoter dynamics MYC oncogene function in cancer progression DNA methylation and demethylation processes Single-cell resolution of transcriptional regulation Carcinogenesis mechanisms His recent publications demonstrate a strong focus on how epigenetic mechanisms influence cancer development, particularly examining MYC's role in regulating transcription through enhancer regions and how epigenetic modifications affect cancer cell behavior. His work bridges fundamental molecular mechanisms with potential therapeutic applications in oncology. Dr. Jakobsen is actively involved in research funding, currently participating in the project 'Transcriptional regulation at single-cell resolution' (2022-2027), which investigates enhancer regions, epigenetics, transcription, and demethylation using advanced single-cell approaches. His research has received significant attention, with multiple media features in March 2024 highlighting new insights into cancer cell growth and spread, suggesting potential targets for future cancer treatments.