جست‌وجوی استاد و پژوهشگر

• Liver Regeneration
• Stem Cell Differentiation
• Hepatic Programming
• +۳ مورد دیگر

Hanne Cathrine Bisgaard is an Associate Professor at the Department of Cellular and Molecular Medicine, Faculty of Health and Medical Sciences, University of Copenhagen. Her research focuses on cellular and molecular mechanisms involved in foetal and adult programming of the mammalian liver, with specific emphasis on stem/progenitor cell differentiation into hepatocytes and cholangiocytes. She also administers the 'Chemical Components of the Cell' course for medical and odontology students. Education: M.Sc. in Biochemistry (1985) Ph.D. (Lic.Scient) in Microbiology, University of Copenhagen, Denmark (1990) Research Interests: Dr. Bisgaard's primary research investigates the characterization of cellular and molecular mechanisms in liver development and regeneration. Her work includes in vitro programming and differentiation of human hepatic progenitor cells, human embryonic stem cells, and induced pluripotent stem cells along hepatic cell lineages. She specifically examines nutritional effects of the microenvironment on differentiation processes and identifies novel molecular mechanisms involved in repair and regeneration of injured liver using experimental animal models in mouse and rat. Current investigations focus on hexose-induced changes in mitochondrial phenotype during liver cell differentiation and developing in vitro systems for studying hepatic differentiation and associated diseases using induced pluripotent stem cells and gene editing. Scientific Awards: Fogarty International Postdoctoral Fellowship, National Institutes of Health, USA (1990-1994) Fellowships from the Danish Cancer Society (1992-1993 and 1994-1995) Fellowship from the Danish Research Academy (1989-1990) Advising and Grants: Dr. Bisgaard has supervised 2 post docs, 12 Ph.D. students, and 14 master students since 1995. She serves as a referee for grant agencies including Welcome Trust, Hungarian Scientific Research Fund (OTKA), and The Danish Multiple Sclerosis Society. Her research has been supported by various fellowships and grants throughout her career. Laboratory and Collaborations: Dr. Bisgaard's laboratory collaborates with researchers including Bjørn Quistorff (Department of Biomedical Sciences), Lene Juel Rasmussen (Center for Healthy Aging), Lisbeth Birk Møller (Medical Genetics Laboratory), and international collaborators like Peter Nagy at Semmelweis University in Budapest. She is actively involved in the Morphogenesis and Differentiation Program at the Department of Cellular and Molecular Medicine.

• Neuro-oncology
• Brain Development
• Cancer Biomarkers
• +۴ مورد دیگر

Camilla Bjørnbak Holst is a Research Fellow at the Department of Cellular and Molecular Medicine, University of Copenhagen, specializing in the Morphogenesis and Differentiation Program. As a medical doctor with expertise in neuro-oncology and developmental neuroscience, she maintains strong affiliations with both clinical and research communities at one of Europe's leading medical institutions. Her educational background includes a Cand. Med. degree in Medicine from the University of Copenhagen, awarded on June 17, 2011. This formal medical training provides the foundation for her current specialized research. Dr. Holst's research focuses on human brain development , cancer biology , and the protein YKL-40, with particular emphasis on its dual roles in both normal neural development and glioblastoma pathogenesis. Her work bridges fundamental developmental neuroscience with translational cancer research, creating a unique interdisciplinary approach to understanding brain disorders. She has established herself as a specialist in analyzing YKL-40's complex functions across different biological contexts. Analysis of her publication record reveals a clear research trajectory examining brain barriers and development (2015-2017), progressing to detailed investigations of astroglial development (2019), and culminating in her current focus on YKL-40 as both a biomarker and therapeutic target in glioblastoma (2021-2024). Her recent publications demonstrate increasing specialization in neuro-oncology while maintaining connections to developmental neuroscience. Dr. Holst actively collaborates within the Morphogenesis and Differentiation Program at the Department of Cellular and Molecular Medicine, working closely with Professor Kjeld Møllgård's research group. Her current PhD study specifically investigates YKL-40 as a biomarker and treatment target in Glioblastoma, representing the culmination of years of focused research on this protein's dual roles in brain development and cancer.

• Orthopaedic Surgery
• Sports Medicine
• Knee Surgery
• +۵ مورد دیگر

Michael R. Krogsgaard serves as a Clinical Professor within the Department of Clinical Medicine, specializing in Orthopaedic Surgery at the University of Copenhagen's Faculty of Health and Medical Sciences. His clinical practice and research are based at Bispebjerg Hospital in Copenhagen, Denmark, where he maintains active roles in patient care, surgical practice, and academic research in musculoskeletal conditions. Dr. Krogsgaard's research primarily focuses on knee and ankle pathology, with particular expertise in patellofemoral instability, ACL reconstruction, ankle ligament injuries, and tissue engineering applications. His work bridges clinical practice with biomechanical analysis, developing standardized assessment tools like the Copenhagen Ankle Range of Motion Scale while investigating surgical outcomes and tissue healing processes. He maintains active collaborations with multidisciplinary teams across physiology, rehabilitation, and basic science disciplines. Analysis of his recent publication record (2024-2025) reveals a consistent emphasis on clinically relevant outcomes research, with particular attention to long-term patient satisfaction, surgical technique optimization, and development of evidence-based treatment algorithms for complex orthopaedic conditions. His work demonstrates integration of biomechanical principles with practical clinical applications. While specific awards aren't detailed in the available information, Dr. Krogsgaard's substantial publication record comprising 130 research outputs—including 113 journal articles, 6 book chapters, and 5 reviews—demonstrates significant scholarly contribution and recognition within the orthopaedic community. Dr. Krogsgaard supervises multiple research projects and collaborates extensively with colleagues across departments and institutions. His work on tissue banking and musculoskeletal allografts suggests leadership in specialized research facilities, while his clinical outcome studies indicate strong connections with rehabilitation services and patient follow-up programs. He appears to secure research funding supporting both basic science investigations and clinical trials. His research activities are conducted through Copenhagen University Hospital and the Department of Clinical Medicine, where he contributes to advancing orthopaedic knowledge while training the next generation of surgeons and researchers in evidence-based surgical practice.

• Pancreatic Cancer Biology
• Transcriptional Regulation
• Non-coding RNAs
• +۵ مورد دیگر

Luis Arnes Perez serves as an Associate Professor at the Novo Nordisk Foundation Center for Stem Cell Biology (DanStem) and the Biotech Research and Innovation Centre (BRIC) at the University of Copenhagen, Denmark, holding a 100% position since 2019. His academic journey includes significant research appointments at Columbia University, where he worked from 2009 to 2018 in various capacities including Postdoctoral Research Scientist, Research Associate, and Associate Research Scientist across the Departments of Genetics and Development and Systems Biology. Dr. Perez completed his PhD in Cellular and Genetic Biology at Autonoma University in Madrid (2004-2009), followed by an MSc in Molecular Biology from the same institution (1999-2004). His research focuses on pancreatic biology, with particular emphasis on transcriptional regulation, non-coding RNAs, and cellular plasticity in both development and cancer progression. His work has made significant contributions to understanding how non-coding RNAs regulate developmental competence in pancreatic lineages and how cell fate transitions occur during pancreatic cancer progression. Analysis of his recent publications reveals a consistent research trajectory centered on pancreatic cancer biology, with increasing focus on tumor microenvironment dynamics, cellular plasticity mechanisms, and translational applications. His work bridges basic developmental biology with cancer research, demonstrating how fundamental mechanisms of pancreas development become dysregulated in disease states. The publications show strong international collaboration patterns, with significant contributions to high-impact journals in gastroenterology, oncology, and cell biology. Berrie Scholar Award at Columbia University Juvenile Diabetes Research Foundation (JDRF) Postdoctoral Fellowship Juvenile Diabetes Research Foundation (JDRF) Transition Award Columbia University Interdisciplinary Research Award Dr. Perez leads the Arnes Lab at DanStem and BRIC, which is dedicated to understanding the non-coding regulation of cellular plasticity and tumor progression in vivo. His research program integrates molecular biology, genetics, and cancer biology approaches to investigate how transcriptional and epigenetic mechanisms maintain cellular identity and how their dysregulation contributes to pancreatic disorders and cancer. The lab appears to collaborate extensively with other research groups at the University of Copenhagen and internationally, as evidenced by the co-authorship patterns in his publications.

• Protein signaling
• Chromosome dynamics
• Cell cycle
• +۵ مورد دیگر

Jiri Lukas serves as Executive Director of the Novo Nordisk Foundation Center for Protein Research (CPR) within the Faculty of Health and Medical Sciences at the University of Copenhagen, where he leads the Lukas Group. His laboratory focuses on understanding protein pathways that orchestrate spatial and temporal dynamics of chromosomes during the mammalian cell cycle and following DNA damage, with particular emphasis on how these mechanisms are subverted in cancer and other diseases associated with unstable genomes. His primary research interests include: Protein signaling pathways in DNA damage response Chromosome dynamics during cell cycle progression Mechanisms of replication stress and DNA repair Chromatin modifications following DNA damage Real-time imaging of signaling and repair proteins High-content microscopy screens for genome caretakers Lukas's research has revealed fundamental mechanisms including ubiquitin-driven signaling pathways that barcode chromatin near DNA lesions to assemble repair proteins, the heritability of chromosomal lesions generated on unreplicated DNA during mitosis, and the concept of rate limitation of nodal signaling components to confine repair reactions to damaged genomic loci. His publication record demonstrates consistent high-impact contributions to the field, with research appearing in top-tier journals including Nature, Science, and Cell, showing particular strength in understanding DNA damage response mechanisms and replication stress. His significant scientific recognition includes: Fernström Foundation Grand Nordic Prize (2016) Leopold Griffuel Prize (2014) Election to the European Academy of Cancer Sciences (2014) Election to the Royal Danish Academy of Sciences and Letters (2012) Danish Society for Cancer Research Award (2010) Danish Cancer Society Senior Research Prize (2008) Election as EMBO Member (2002) As Executive Director of CPR since 2012, Professor Lukas has overseen significant growth in protein research capabilities while maintaining an active laboratory program. His work bridges basic science with potential clinical applications in cancer treatment, particularly through understanding how genome instability contributes to disease development. The Lukas Group maintains active collaborations across multiple institutions and has developed innovative approaches for studying DNA damage response in real time.

• Vascular Surgery
• Endovascular Surgery
• Aortic Aneurysm Management
• +۳ مورد دیگر

Louise Rosenørn de la Motte serves as a Clinical Associate Professor in the Department of Clinical Medicine at the University of Copenhagen, Denmark, with clinical practice based at the Capital Region of Denmark (Region H) in Copenhagen. Her work bridges vascular surgery research and clinical practice, focusing on translational applications in endovascular techniques and surgical education. Her research expertise centers on: Vascular and endovascular interventions for aortic and mesenteric pathologies Development of competency assessment tools for complex surgical procedures Simulation-based training methodologies for vascular trainees Advanced imaging characterization of vascular diseases National cohort studies evaluating surgical outcomes Analysis of her publication trajectory (2009-2021) reveals an evolution from foundational work in aortic imaging and hybrid surgical techniques toward contemporary research in endovascular optimization and surgical education. Recent studies (2020-2021) emphasize competency validation frameworks, intensive training protocols for EVAR sizing, and national outcome analyses for mesenteric ischemia – demonstrating consistent focus on improving procedural safety and training efficacy. Earlier work (2009-2013) established her contributions to thrombus morphology characterization and hybrid aortic repair approaches. Scientific recognition: No specific awards documented in available sources Publications referenced in clinical guidelines (2021 mesenteric ischemia study) Significant scholarly engagement (12+ X mentions, 40+ Mendeley readers per recent publication) Her collaborative network includes prominent vascular researchers like Dr. Lars Konge (surgical simulation) and Dr. Jesper Eiberg, indicating active participation in funded research consortia. While specific advising roles aren't detailed, her simulation-focused publications suggest mentorship of vascular trainees through structured educational programs. She operates within Copenhagen's integrated academic-clinical vascular research ecosystem, contributing to both peer-reviewed scholarship and clinical guideline development.

• Pathology
• Oncology
• Pancreatic Cancer Research
• +۴ مورد دیگر

Jane Preuss Hasselby serves as a Clinical Associate Professor in the Department of Clinical Medicine, specializing in Pathology at the University of Copenhagen's Faculty of Health and Medical Sciences. She is based at Blegdamsvej 3 in Copenhagen and maintains strong affiliations with Region Hovedstaden (Region H), as evidenced by her institutional email address. Her academic position reflects her dual expertise in clinical practice and research within the Danish healthcare system. Dr. Hasselby's research program focuses on pancreatic pathology, cancer biology, and the application of immunotherapy in gastrointestinal malignancies. Her work spans from fundamental investigations of pancreatic regeneration and injury response mechanisms to clinical studies evaluating novel cancer treatments. She has established particular expertise in pathological analysis of surgical specimens, with emphasis on margin clearance in pancreatic cancer resections and immune microenvironment characterization. Her research demonstrates strong translational value, bridging laboratory findings with clinical applications in oncology. Analysis of her recent publications reveals a cohesive research trajectory centered on pancreatic cancer pathogenesis and treatment response. She frequently leads or contributes to multidisciplinary studies that integrate pathology, oncology, surgery, and immunology, often within the context of large Danish population-based cohorts or clinical trials. Her work shows increasing emphasis on combination immunotherapy approaches and their underlying biological mechanisms, with several publications examining how immune responses correlate with treatment outcomes in gastrointestinal cancers. Dr. Hasselby actively participates in clinical research through collaborations with major Danish cancer centers, including involvement in multiple phase 2 clinical trials investigating novel treatment approaches for pancreatic and biliary tract cancers. Her collaborative network extends across pathology departments, oncology units, and research institutions throughout Denmark, reflecting her role as a key contributor to gastrointestinal cancer research in the Nordic region.

• Transcription
• RNA Biology
• Genome Stability
• +۳ مورد دیگر

Zhong Han serves as a Guest Researcher in the Department of Cellular and Molecular Medicine at the University of Copenhagen, affiliated with the Transcription, RNA, and Gene Medicine Program at Blegdamsvej 3, Copenhagen. Working within the Svejstrup group, Han investigates critical intersections between transcription and DNA maintenance processes including repair, replication, and recombination. Research centers on transcription's impact on genome stability—a key factor in cancer development where gene expression deregulation and genomic instability co-occur. Primary interests encompass RNA polymerase II mechanisms, DNA-directed termination, stress-induced transcriptome reconfiguration, and kinase-mediated elongation control. Methodologies integrate biochemical, genetic, and cell biological techniques predominantly in human cellular systems. Recent publications reveal a cohesive investigative trajectory across five years: from foundational transcription termination mechanisms (2021-2023) to kinase regulation in elongation (2025) and stress-response protocols (2024). Work consistently appears in elite journals like Molecular Cell , emphasizing molecular pathology with translational relevance to oncology. No scientific awards or fellowships are documented in available materials. Information regarding student mentorship and research funding remains unspecified in current profiles. The Svejstrup group's collaborative framework employs multidisciplinary approaches to dissect transcription-genome integrity relationships, with implications for understanding cancer etiology and developing therapeutic interventions.

• Genetics
• Reproductive Biology
• Chromosome Biology
• +۵ مورد دیگر

Jennifer Rose Gruhn is an Assistant Professor in the Department of Cellular and Molecular Medicine at the University of Copenhagen, working within the Molecular Aging Program. She is an active member of the Hoffmann Group, where she conducts research at the intersection of reproductive biology, chromosome dynamics, and aging. Dr. Gruhn's research focuses on understanding the fundamental mechanisms of human reproduction, particularly the high error rates in chromosome segregation during egg development. Her work addresses why human reproduction is particularly error-prone, with 50% of pre-implantation embryos showing developmental defects and 20%-85% of human eggs exhibiting aneuploidy (extra or missing chromosomes). Maternal age is identified as the strongest risk factor for aneuploidy, making reproductive aging a central focus of her investigations. Her recent publications reveal a consistent research trajectory examining the molecular basis of chromosomal abnormalities in human reproduction. Studies span from basic mechanisms of DNA repair and chromosome recombination to clinical applications in pregnancy loss diagnostics. Her work combines model organisms (mouse and yeast) with human egg and embryo research to investigate the DNA damage response and cell cycle proteins governing genetic changes in the germline. Dr. Gruhn has been involved in significant collaborative efforts, including the Copenhagen Pregnancy Loss Study (COPL), which has generated high-impact publications in journals like Nature and The Lancet. Her research has garnered substantial attention, with multiple papers picked up by news outlets, blogged about, and widely shared on social media platforms. As part of the Hoffmann Group, Dr. Gruhn contributes to advancing our understanding of the genetic changes that occur during human reproduction, with implications for both reproductive health and cancer research, as many of the same genes involved in maintaining germline genome stability are also implicated in oncogenesis.

• Vascular Surgery
• Atherosclerosis Research
• Carotid Plaque Imaging
• +۳ مورد دیگر

Martin Græbe serves as a Clinical Associate Professor within the Department of Clinical Medicine at the University of Copenhagen's Faculty of Health and Medical Sciences, specializing in Vascular Surgery. Based at Blegdamsvej 3 in Copenhagen, Denmark, his clinical and research activities focus on advanced vascular diagnostics and interventions, with particular emphasis on carotid disease and atherosclerosis management. Dr. Græbe's research program centers on vascular imaging biomarkers, investigating how ultrasound and PET techniques can characterize plaque composition, stability, and inflammatory activity. His work bridges molecular biology with clinical imaging, exploring connections between FDG uptake, hypoxia markers like HIF-1α, and microvessel density in atherosclerotic plaques. This research has important implications for predicting stroke risk and monitoring disease progression. Analysis of his publication timeline reveals consistent contributions to vascular imaging methodology, particularly in 3D ultrasound applications and PET quantification techniques for plaque assessment. His research demonstrates how imaging findings correlate with underlying molecular processes and clinical outcomes, providing valuable insights for improving diagnostic accuracy and treatment strategies in vascular medicine. Dr. Græbe maintains an active collaborative network across multiple disciplines, as evidenced by his co-authorship on publications spanning vascular surgery, nuclear medicine, and cardiovascular research. His work has received citations across various publications, with several papers garnering significant attention in the vascular research community, reflecting his contributions to advancing diagnostic approaches in vascular disease management.

• Molecular Pathology
• Colorectal Cancer Genetics
• Lynch Syndrome
• +۴ مورد دیگر

Louise Laurberg Klarskov serves as Clinical Associate Professor in the Department of Clinical Medicine within the Faculty of Health and Medical Sciences at the University of Copenhagen. Her primary affiliation is with the Pathology unit at Copenhagen University Hospital (Region Hovedstaden), located at Blegdamsvej 3 in Copenhagen N. She maintains active clinical and research roles focused on molecular pathology of gastrointestinal malignancies. Her research concentrates on hereditary and molecular aspects of colorectal cancer, particularly Lynch syndrome surveillance, mismatch repair deficiency mechanisms, and genomic characterization of treatment-resistant tumors. Current investigations include pembrolizumab therapy for dMMR colorectal cancer and pancreatic cancer sequencing methodologies. Her work demonstrates strong translational focus with direct clinical implementation pathways. Analysis of her 16 research outputs (2021-2025) reveals consistent contributions to oncology journals including Anticancer Research , Translational Oncology , and Hereditary Cancer in Clinical Practice . Key thematic clusters include: (1) MMR deficiency screening implementation in Danish healthcare, (2) Molecular evolution of Lynch-associated cancers, (3) Genomic profiling of pancreatic and colorectal carcinomas, and (4) Diagnostic pathway optimization for abdominal conditions. Her collaborative network spans major Danish medical institutions including Rigshospitalet, Herlev Hospital, and Aarhus University Hospital, with international connections to European Lynch syndrome consortia. Notable policy impact includes referenced guidelines for universal MMR screening in colorectal cancer. Dr. Klarskov's clinical research directly informs national cancer screening protocols, particularly regarding colonoscopy surveillance intervals for mutation carriers and molecular testing standardization. Her work bridges laboratory genomics with clinical oncology practice through multicenter Danish registry studies and prospective therapeutic trials.

• Colorectal Cancer
• Surgical Oncology
• Postoperative Care
• +۵ مورد دیگر

Lars Nannestad Jørgensen serves as Clinical Professor at the Department of Clinical Medicine, University of Copenhagen, with clinical affiliations at Bispebjerg Hospital (Bispebjerg Bakke 23) and Rigshospitalet (Blegdamsvej 3) in Copenhagen. His dual appointment bridges surgical practice and academic research within Denmark's public healthcare system, focusing on gastrointestinal malignancies and perioperative care. His research program centers on translational surgical oncology, particularly colorectal cancer screening optimization through liquid biopsy technologies and fecal immunochemical testing. Key investigations include postoperative monitoring systems for early complication detection, cost-effectiveness analyses of cancer screening programs, and novel biomarker discovery in pancreatic cancer. Recent work explores the intersection of artificial intelligence and medical education, examining large language model applications in surgical research. Analysis of his 2024-2025 publications reveals strong emphasis on colorectal cancer diagnostics (62.5% of recent work), with significant contributions to perioperative monitoring technology and healthcare economics. Emerging trends include integration of circulating tumor DNA in screening protocols and rigorous evaluation of AI tools for surgical research abstract generation. His extensive publication record (256 outputs including 223 journal articles) demonstrates substantial collaborative networks across Danish hospitals and international institutions. Social media impact is notable with 18 X (Twitter) mentions for his colorectal cancer cost study and 40 Mendeley readers for his pancreatic cancer biomarker research, indicating significant clinical relevance.

Mai-Britt Tolstrupمشاهده پروفایل

دانشیار بالینی

• Emergency Abdominal Surgery
• Surgical Strategies
• Patient Morbidity
• +۵ مورد دیگر

Mai-Britt Tolstrup serves as a Clinical Associate Professor at the Department of Clinical Medicine, Faculty of Health and Medical Sciences, University of Copenhagen, while simultaneously holding the position of Chief Surgeon at the Department of Surgery, Copenhagen University Hospital NOH since 2021. She maintains a dual appointment between the Capital Region of Denmark and the University of Copenhagen, reflecting her integrated clinical and academic career spanning over 20 years in emergency surgery. Dr. Tolstrup's research interests center on intra- and postoperative surgical strategies, particularly focusing on emergency abdominal procedures. Her work extensively examines patient morbidity and mortality, risk prediction models, and both short- and long-term patient-reported outcomes following emergency surgeries. She has developed significant expertise in areas such as burst abdomen management, small bowel anastomosis techniques, sarcopenia assessment, and delirium prevention protocols in the surgical population. Analysis of her recent publication record (2019-2025) reveals a consistent focus on improving outcomes in emergency abdominal surgery, with particular emphasis on preventing complications like burst abdomen, incisional hernias, and postoperative delirium. Her research demonstrates a methodological evolution from case-control and retrospective cohort studies toward interventional approaches and systematic reviews, indicating maturation of her research program toward evidence-based practice implementation. As a clinical educator and researcher, Dr. Tolstrup has contributed significantly to the understanding of emergency surgical care pathways, with her work being cited extensively across international surgical literature. Her research has practical implications for surgical decision-making, particularly regarding bowel obstruction management, anastomosis techniques in emergency settings, and risk stratification for high-mortality patient populations such as those with liver cirrhosis.

• Cancer Genomics
• Genome Instability
• DNA Repair
• +۷ مورد دیگر

Fran Supek is a Professor at the University of Copenhagen's Faculty of Health and Medical Sciences, where he leads the Genome Data Science laboratory at the Biotech Research & Innovation Centre (BRIC). He also maintains a research group at the IRB Barcelona. Supek is the Principal Investigator of ERC Starting and ERC Consolidator projects, an EMBO Young Investigator, and holds an ICREA tenured professor position (currently on leave). Dr. Supek obtained his PhD in Molecular Biology in 2010 from the University of Zagreb, followed by postdoctoral training at the Centre for Genomic Regulation (CRG) as a Marie Curie fellow. He established his independent laboratory at IRB Barcelona in 2017 as a "Ramón y Cajal" tenure-track fellow, and expanded to BRIC in 2024. His research focuses on statistical genomics and machine learning approaches to study genome stability mechanisms, particularly through analysis of mutation patterns in cancer. The Genome Data Science lab performs large-scale bioinformatic studies of multi-omic data from human tumors, populations, and metagenomes. Key research areas include DNA repair mechanisms, mRNA synthesis and turnover pathways, genetic interactions in cancer genomes, and machine learning approaches for inferring gene function from genomic data. Analysis of Supek's recent publications reveals a strong emphasis on cancer genomics, with particular focus on mutational signatures, DNA repair deficiencies, and the application of artificial intelligence to genomic data analysis. His work spans from fundamental mechanisms of genome instability to translational applications in cancer diagnosis and treatment. ERC Starting Grant recipient ERC Consolidator Grant recipient EMBO Young Investigator ICREA tenured professor (on leave) As Principal Investigator of multiple ERC projects, Supek leads a research program with significant funding for innovative genomic research. His laboratory at BRIC and IRB Barcelona conducts interdisciplinary research combining computational approaches with experimental validation to address fundamental questions in genome biology and cancer evolution. The Genome Data Science lab maintains active collaborations across multiple institutions, with research spanning statistical genomics, machine learning applications in bioinformatics, and experimental validation of computational predictions in cancer biology.

• Cancer Genomics
• DNA Repair
• Aging Research
• +۲ مورد دیگر

Simon Grund Sørensen is a Guest researcher at the Department of Cellular and Molecular Medicine within the Faculty of Health and Medical Sciences at the University of Copenhagen, affiliated with the Molecular Aging Program focused on molecular mechanisms of aging and age-related diseases. His research spans Cancer Genomics, DNA Repair, Aging Research, Molecular Biology, and Bioinformatics, investigating how DNA repair deficiencies drive characteristic mutational patterns across cancer types through genomic and computational approaches. This integrates molecular aging processes with cancer etiology to identify underlying genomic instability mechanisms. His 2023 eLife publication on pan-cancer DNA repair deficiencies exemplifies his work in genomic analysis, revealing how defective repair pathways generate mutation signatures across diverse cancers. This research bridges cancer genomics and aging biology by connecting DNA repair mechanisms to genome-wide mutational landscapes. No information is available regarding scientific awards, student advising, or research grants. Dr. Sørensen conducts research within the Molecular Aging Program, a collaborative initiative studying molecular aging pathways to develop interventions for age-related diseases like cancer.