جستجوی استاد راهنمای دانشگاهی

Silke Robatzekمشاهده پروفایل

استاد

• Plant Genetics
• Plant Immunology
• Microbial Pathogenesis
• +۳ مورد دیگر

Silke Robatzek is a Professor in the Department of Genetics at LMU Munich's Faculty of Biology. Her research focuses on plant immune signaling mechanisms and their regulation of host-microbe interactions, particularly regarding pathogens like Xylella fastidiosa and Phytophthora infestans . Current member of Graduate School Life Science Munich Research themes: plant immune receptors, extracellular vesicles, microbial homeostasis, stomatal immunity, pathogen effectors Key methodologies: quantitative imaging, proteomic analyses, receptor trafficking studies Recent research trends show heavy emphasis on extracellular vesicles and their roles in plant-pathogen communication, receptor kinase signaling (e.g., QSK1, SOBIR1), and microbiome dynamics in disease resistance. Her work spans molecular mechanisms (S-acylation, phosphorylation) to ecological implications in sustainable agriculture. Contact: robatzek@biologie.uni-muenchen.de

• Innate Immunity
• Pattern Recognition Receptors
• Cancer Immunology
• +۳ مورد دیگر

Nadra Jesmine Nilsen is a Senior Research Scientist at the Norwegian University of Science and Technology (NTNU), affiliated with the Centre of Molecular Inflammation Research (CEMIR), the Center for Myeloma Research, and the Colorectal Cancer (CRC) Research Center. Her research focuses on innate immunity mechanisms, particularly pattern recognition receptors (PRRs) and their roles in cancer progression, including Multiple Myeloma and colorectal cancer. She holds expertise in immunology, molecular medicine, and cell biology. Her competencies span biochemistry, cancer immunology, and confocal microscopy. She has contributed to over 15 peer-reviewed publications since 2003, exploring topics like TLR signaling pathways, cytokine regulation, and cancer metastasis. Notable work includes studies on TLR3's role in promoting invasiveness of metastatic intestinal epithelial cells (2017) and TRAM/TRIF adaptor proteins in TLR2 signaling (2015). Nilsen has presented at international conferences, including the Toll2018 Symposium in Porto and the International Congress of Immunology in Kobe. Her research bridges basic science and translational applications, targeting innate immunity mechanisms in oncology and inflammatory diseases.

Banu Bayyurt Kocabaşمشاهده پروفایل

استادیار

• Immunology
• Pattern Recognition Receptors
• Innate Immunity
• +۵ مورد دیگر

Banu Bayyurt Kocabaş is an Assistant Professor in the Department of Biological Sciences at Middle East Technical University (METU) in Ankara, Turkey, specializing in immunology research. Her work focuses on understanding host-microbe interactions at molecular and cellular levels with particular emphasis on the immune system's defense mechanisms. Her educational background includes: Ph.D. in Molecular Biology and Genetics from Bilkent University (2011-2017) M.Sc. in Biotechnology from Middle East Technical University (2006-2009) B.Sc. in Biology from Hacettepe University (2002-2006) Prior to her faculty position, she completed a postdoctoral fellowship at the National Institutes of Health (NIH) in Bethesda, Maryland (2017-2022). Dr. Kocabaş's research program investigates how pattern recognition receptors (PRRs) distinguish self from non-self and how these receptors are regulated through various molecular mechanisms. Her laboratory pursues four main research directions: Designing novel immunostimulant agents and vaccines using immunoengineering and nanobiotechnology against cancer and infectious diseases Identification of new regulation mechanisms of pattern recognition receptors, particularly RIG-I receptor Elucidation of PRR regulation mechanisms in terms of age-specific differences Understanding the evolutionary role of viruses in innate immune system development Her publication record demonstrates a consistent trajectory from fundamental immunological research to translational applications, with recent work (2024) focusing on cancer vaccine development using extracellular vesicles as delivery systems. Among her scientific recognitions, she received The Işıl Berat Barlan Award 2023 as a young scientist at the XXVI. National Immunology Congress in Ankara, Turkey. Dr. Kocabaş actively mentors graduate students, with laboratory members Havva and Nuride recently presenting their thesis work at national immunology conferences. Her research appears to be supported by funding sources including TUBITAK 2224-A, as indicated by conference support for her students. Her laboratory maintains an active research program at the intersection of immunology, nanotechnology, and biotechnology, with a strong emphasis on developing novel therapeutic approaches for cancer and infectious diseases through innovative delivery systems and immunomodulation strategies.

• Glycobiology
• Glycoimmunology
• Lectins
• +۸ مورد دیگر

Dr. Gerardo Vasta is a Professor in the Department of Microbiology and Immunology at the University of Maryland School of Medicine, with a multidisciplinary background in biochemistry, zoology, and immunology. His research focuses on glycosciences, particularly protein-carbohydrate interactions in innate immunity, cancer, and developmental biology. National University La Plata: Chemist (1972), Licenciate in Biochemistry (1973), Licenciate in Zoology (1976), PhD in Biochemistry (1978), PhD in Zoology (1980) Roswell Park Memorial Institute: Post-Doctoral Fellow (1979-1980) Medical University of South Carolina: Post-Doctoral Fellow (1981-1982), Research Associate (1982-1984) His work bridges structural biology and immunology, using zebrafish, C. elegans, eastern oyster, and murine models to investigate galectins' roles in immune regulation, pathogen recognition, and cancer diagnostics. Current projects examine galectin mechanisms in lung infections and viral interactions. Recent publications highlight galectin-mediated immune responses, bacterial adhesion inhibition, and glycan-based therapeutic strategies. Articles focus on zebrafish models, marine pathogens, and translational applications of lectin research. Honor Student Award, Mar del Plata City Council (1968-1973) Fogarty Fellowship, NIH (1981-1983) J. William Fulbright Scholar (2007) National Award 'Raíces', Argentina (2016) Dr. Vasta mentors graduate students and hosts summer interns. His lab receives funding from NSF, NIH, NOAA, and NIH study sections. He serves on editorial boards for Glycobiology and Invertebrate Immunity.

Mari L. Shinoharaمشاهده پروفایل

استاد

• Integrative Immunobiology
• Neuroimmunology
• Innate Immunity
• +۷ مورد دیگر

Mari L. Shinohara is Professor of Integrative Immunobiology at Duke University School of Medicine , where she also holds professorships in Cell Biology , Neurobiology , and Molecular Genetics & Microbiology . She serves as Director of Graduate Studies in the Department of Immunology and is a member of the Duke Institute for Brain Sciences and the Duke Cancer Institute . Education & Training: While specific degrees are not detailed in the provided text, Dr. Shinohara’s extensive publication record and senior faculty status indicate advanced training in immunology and molecular biology. Research Overview: The Shinohara Lab investigates the cellular and molecular mechanisms that balance protective immunity against pathogens with the prevention of autoimmunity. Using cutting-edge mouse models of multiple sclerosis (EAE) , fungal infections , and graft-versus-host disease , the lab focuses on: Pattern Recognition Receptors (PRRs) in macrophages and dendritic cells Osteopontin (OPN) isoforms in immune regulation Neuro-immune interactions in the CNS during infection and autoimmunity Alveolar macrophage heterogeneity and lung immunity Inflammasome biology in astrocytes and microglia Scientific Awards & Honors: While no personal awards are listed, her trainees have received prestigious recognitions such as the NSF Graduate Research Fellowship . Advising & Grants: Dr. Shinohara has mentored numerous PhD students to successful defense, including Jeremy Ratiu , William Barclay , and Elizabeth Deerhake . Her lab is supported by active federal and foundation grants, though specific grant numbers are not disclosed here. Laboratory & Resources: The Shinohara Lab is located in the Jones Building on Duke’s Research Drive, with access to core facilities through the School of Medicine and the Office of Biomedical Graduate Education.

Vardis Ntoukakisمشاهده پروفایل

استاد

• Plant Immunity
• Pathogen Recognition
• Molecular Biology
• +۳ مورد دیگر

Professor Vardis Ntoukakis is affiliated with the School of Life Sciences at the University of Warwick, UK, where he has served since 2021. His research focuses on plant-pathogen interactions and molecular defense mechanisms. Director of BBSRC Midlands Integrative Biosciences Training Partnership His research combines genomic technologies (mRNA-seq, ChIP-seq) and biochemistry to study plant immunity activation through Pattern Recognition Receptors (PRRs) and Resistance (R) proteins. Key applications include crop resistance engineering and yield improvement under climate change pressures. His work has been supported by the Royal Society through a University Research Fellowship (2012-2021). Collaborations and PhD/postdoctoral opportunities are available via direct contact at his office (B175 Research Clusters) or email. PhD in Biochemistry (2005), University of California Riverside, US BSc in Agriculture (1996), Aristotle University, Greece Notable career positions include: Post-doctoral researcher at The Sainsbury Laboratory (2011-2012, 2005-2008) Post-doctoral researcher at John Innes Centre (2008-2011)

• Innate Immunology
• Virology
• Viral Evasion
• +۷ مورد دیگر

Professor Andrew Bowie is a Professor of Innate Immunology and Biochemistry at Trinity College Dublin, where he serves as Head of the School of Biochemistry and Immunology. His research focuses on innate immune sensing mechanisms and their modulation by viruses, establishing him as a global leader in this field. Bowie obtained his PhD in Biochemistry from Trinity College Dublin in 1997, following postdoctoral training with Prof Luke O'Neill. He was appointed as lecturer in the Department of Pharmacology in UCD before returning to TCD in 2001 to establish Ireland's first Immunology undergraduate degree course, which he coordinated from 2002-2006. He served as Director of Research in the School of Biochemistry and Immunology from 2005-2009, and as Head of Immunology from 2011-2017. His research occupies a unique space at the interface between virology, immunology and disease pathogenesis. He investigates how pattern recognition receptors (PRRs) recognize pathogens, leading to interferon and cytokine production, and discovered IFI16 as a key cellular DNA sensor in 2010. His work has shed light on viral immune evasion mechanisms and how innate immune sensors drive inflammation. His laboratory has identified novel roles for innate immune proteins in regulating inflammation through cytokine modulation. Analysis of his recent publications reveals continued leadership in innate immunity research with a focus on viral sensing mechanisms, DNA recognition systems, inflammation regulation, and host-pathogen interactions. His work spans fundamental immunology to potential therapeutic applications, with publications in top journals including Nature Communications, Cell Reports, and Immunity. Highly cited researcher (Clarivate, top 1% by citations) 2018 Irish Society for Immunology Public Lecture Award Medal 2017 Elected to the Royal Irish Academy 2014 Elected Fellow of TCD 2008 Sheldon Wolff Prize in Cytokine Research 1999 Placed first in class (B.A. (Mod)) 1993 Professor Bowie has graduated 14 PhD students to date and secured over €9 million in research funding from national and international agencies including Science Foundation Ireland, the EU, and the US National Institutes of Health, as well as private industry. His laboratory investigates how pathogens engage with human cells through pattern recognition receptors and how viruses evade immune detection. He is actively involved in both undergraduate and postgraduate Immunology teaching, contributing significantly to TCD's global reputation as a center of excellence for Immunology teaching and research.

• Plant Immunity
• Signal Transduction
• Pattern Recognition Receptors
• +۳ مورد دیگر

Stefanie Ranf-Zipproth is a Professor at the Department of Biology, University of Fribourg, Switzerland. Her research focuses on molecular mechanisms of plant immunity, particularly pattern recognition receptors (PRRs), signal transduction, and plant-microbe interactions. University: University of Fribourg Faculty: Faculty of Science and Medicine Department: Department of Biology Academic Rank: Professor Email: stefanie.ranf-zipproth@unifr.ch Research Interests: Stefanie Ranf-Zipproth investigates the molecular basis of plant innate immunity, with emphasis on: Pattern recognition receptors (PRRs) and microbe-associated molecular patterns (MAMPs) Signal transduction mechanisms, including phosphorylation and calcium signaling Receptor-like kinase (RLK) activation and regulation Role of sphingolipids and glycosylation in immune responses Cross-family transfer of immune receptors for crop protection Interaction between plant immune systems and bacterial metabolites Publication Trends: Her recent work explores the application of pattern recognition receptors across plant species, molecular signaling pathways in Arabidopsis, and the role of lipid modifications in immune activation. Key themes include plant defense against bacterial and fungal pathogens, receptor complex dynamics, and translational applications for sustainable agriculture. Grant Funding: Currently leading a research project on "Molecular mechanisms of early LORE immune signaling" (2022-2026), funded by the Swiss National Science Foundation (SNSF). This project investigates SD-RLK signaling mechanisms using advanced biochemical, genetic, and computational approaches.

Stanley M. Lemonمشاهده پروفایل

استاد

• Virology
• Hepatitis Virus Research
• RNA Virus Replication
• +۷ مورد دیگر

Dr. Stanley M. Lemon is a Distinguished Professor in the UNC School of Medicine , holding appointments in both the Department of Infectious Diseases and the Department of Microbiology and Immunology . As a member of the UNC Lineberger Comprehensive Cancer Center , his research explores the intricate interplay between hepatotropic positive-strand RNA viruses and host cellular machinery, spanning from acute hepatitis to oncogenic transformations. Member, UNC Lineberger Comprehensive Cancer Center Professor, UNC-Chapel Hill (since 1977) Research Focus encompasses: Molecular mechanisms of HAV and HCV replication Structural analysis of 5’/3’ UTRs and IRESs miR-122 interactions in HCV replication Host innate immune sensor responses to viral RNA Quasi-enveloped HAV immune evasion strategies Recent Discoveries include the role of PDAP1 in hepatitis A virus translation under stress conditions, challenging classical virology paradigms. His laboratory identified cis-acting RNA elements in picornaviruses and mapped microRNA-mediated viral replication pathways. Scientific Recognition : 2024: Elected to National Academy of Sciences 2018: Sabin Lecturer (European Picornavirus Group) 2009: John Enders Award (IDSA) 2007: AAAS Fellow Collaborative Networks extend across the UNC Gene Therapy Center and international virology consortia. His work bridges infectious disease mechanisms with broader implications for cancer biology and metabolic disorders .

• Trauma Surgery
• Blast Injury
• Stem Cell Research
• +۷ مورد دیگر

Thomas A. Davis, PhD, serves as Professor and Vice Chair of Research in the Department of Surgery at the Uniformed Services University of the Health Sciences (USUHS) School of Medicine. With over 45 years of extensive expertise, Dr. Davis has established himself as a leading researcher in trauma surgery and regenerative medicine within the military medical community. Dr. Davis's educational background includes: PhD in Immunology, George Washington University (1993) M.S. in Immunology and Microbiology, George Mason University (1987) B.S. in Biology, George Mason University (1983) Dr. Davis maintains a central research focus on the mechanisms underlying acute cellular and organ injury in inflammatory conditions such as shock, trauma, and sepsis. His laboratory investigates two primary interconnected areas: understanding the early inflammatory response to trauma and developing innovative regenerative tissue therapies. His work on damage associated molecular pattern molecules (DAMPs) and pattern recognition receptors (PRR) has significantly advanced our understanding of post-traumatic inflammatory cascades. Additionally, his research on heterotopic ossification, stem cell biology, and tissue regeneration has practical applications for combat casualty care and military medicine. Analyzing his recent publication trends (2022-2025), Dr. Davis's research demonstrates a strong emphasis on blast injury mechanisms, heterotopic ossification, and the systemic inflammatory response to trauma. His work frequently employs rodent and swine models to study extremity trauma, with particular attention to the connections between cutaneous burn injuries and ectopic bone formation. A notable trend is his increasing focus on biomarker discovery for remote organ dysfunction following blast injuries, reflecting the military medical community's need for early diagnostic tools in combat settings. Dr. Davis's scientific recognition includes: 2023 USUHS School of Medicine Impact Award 2023 Military Health System Research Symposium's Distinguished Service Award In addition to his research leadership as Vice Chair of Research, Dr. Davis actively contributes to academic training as a PhD program professor in Molecular and Cell Biology. His laboratory receives substantial funding from the Department of Defense and USUHS, supporting multiple research projects including combat-applicable lower extremity trauma models and early diagnosis strategies for post-traumatic heterotopic ossification. Dr. Davis serves as an ad hoc reviewer for numerous journals in his field and has mentored numerous medical and graduate students through trauma-related research projects. Dr. Davis leads a multidisciplinary research team focused on advancing the field of tissue engineering and regenerative medicine for military applications. His laboratory develops new cell-based therapies for conditions resulting from combat injuries, including heterotopic ossification, fractures, bone loss, muscle loss, and cartilage injuries. The team is particularly focused on establishing new methods for measuring stem and progenitor cells in various tissues, which has broad implications for cell and gene therapy across military medicine.

• Traumatic Injury
• Blast Injury
• Stem Cell Biology
• +۱۰ مورد دیگر

Thomas A. Davis, PhD is a Professor and Vice Chair of Research in the Department of Surgery at the Uniformed Services University of the Health Sciences (USUHS) School of Medicine. With over 45 years of research experience, Dr. Davis leads trauma and regenerative medicine research initiatives focused on military medical applications. His work bridges basic science with clinical translation to address combat-related injuries. Dr. Davis received his educational training at: PhD in Immunology from George Washington University (1993) M.S. in Immunology and Microbiology from George Mason University (1987) B.S. in Biology from George Mason University (1983) Dr. Davis's research centers on understanding the mechanisms of acute cellular and organ injury in inflammatory states such as shock, trauma, and sepsis. His laboratory investigates two primary areas: the innate immune response to traumatic injury, with emphasis on damage associated molecular pattern molecules (DAMPs) and pattern recognition receptors (PRR), and the development of regenerative tissue approaches for musculoskeletal trauma. His work employs diverse models including blast injury, hemorrhagic shock, burn injury, and severe musculoskeletal tissue loss. Analysis of Dr. Davis's recent publications reveals a strong focus on combat-related trauma, particularly blast injuries and their complications. His research integrates molecular biology, immunology, and tissue engineering to address military-relevant medical challenges. Key themes include heterotopic ossification following blast injuries, neuroinflammatory responses to trauma, and the development of combat-applicable trauma models. Dr. Davis has received prestigious recognition for his contributions to military medicine: 2023 USUHS School of Medicine Impact Award 2023 Military Health System Research Symposium's (MHSRS) Distinguished Service Award As Vice Chair of Research, Dr. Davis oversees multiple funded projects supported by the Department of Defense. His research portfolio includes development of combat-applicable lower extremity trauma models and early diagnosis strategies for post-traumatic heterotopic ossification. He serves on committees including the MCB Qualifying Exam Committee and as an MHSRS Abstract Reviewer, mentoring the next generation of military medical researchers. Dr. Davis leads a research team focused on advancing regenerative medicine approaches for traumatic injuries. His laboratory develops innovative cell-based therapies for conditions like heterotopic ossification and critical tissue loss, with emphasis on establishing new methods for measuring stem and progenitor cells to advance cell and gene therapy applications.

Rodrigo Santosمشاهده پروفایل

پژوهشگر

• Virology
• Antiviral Research
• Immunopathogenesis
• +۵ مورد دیگر

Rodrigo Santos, Ph.D., is a virologist affiliated with the Microbiology and Immunology Department at Campbell University School of Medicine (CUSOM). He holds a Master’s and Doctorate from the University of São Paulo School of Medicine. His research focuses on antiviral mechanisms, viral evasion of immune responses, and immunopathogenesis of viruses like Ebola, Flavivirus, and Oropouche virus. At CUSOM, he investigates how viruses evade Pattern Recognition Receptors (PRRs) using Flavivirus as a model. Dr. Santos previously conducted research at the University of Texas Medical Branch (UTMB), where he studied Ebola virus antibody mechanisms. His work emphasizes tick-borne viruses, viral entry pathways, and host immune interactions. His expertise spans experimental models, immunohistochemical techniques, and GLP-compliant industry research. He joined CUSOM in 2024 and is dedicated to mentoring students in virology and scientific inquiry. His research highlights include studies on Ebola virus T-lymphocyte depletion, antibody-dependent enhancement, and mechanisms of viral evasion through PRR manipulation. Current projects explore Flavivirus neuroinvasion and tick-virus transmission dynamics. While no formal grants or awards are listed, his work contributes significantly to understanding viral pathogenesis and antiviral strategies.

Cyril Zipfelمشاهده پروفایل

استاد

• Plant Immunity
• Pattern Recognition Receptors
• Receptor Kinases
• +۴ مورد دیگر

Cyril Zipfel is Professor and Head of the Molecular and Cellular Plant Physiology group at the University of Zurich's Department of Plant and Microbial Biology. His research investigates plant immune recognition mechanisms with applications in crop disease resistance. Research Focus: The Zipfel lab studies how plants perceive environmental threats through cell surface-localized pattern recognition receptors (PRRs). Research combines molecular genetics, biochemistry, and synthetic biology to understand receptor kinase signaling in plant immunity. Current projects include receptor engineering for improved disease resistance, evolution of immune receptors, and identification of microbial patterns. Funding: Research supported by projects including DyHealthNet (exploring CHRIS cohort data) and Temporal RDBMS (PostgreSQL extensions for temporal queries). Teaching: Supervises PhD students in plant-microbe interactions and teaches plant immune signaling concepts.

Mayda Gürselمشاهده پروفایل

استاد

• Immunology
• Vaccine Development
• Molecular Biology
• +۳ مورد دیگر

Mayda Gürsel is a Professor in the Department of Biological Sciences at Middle East Technical University (METU). Her research focuses on innate immune responses mediated by host pattern recognition receptors (PRRs), with active projects in immunotherapeutic adjuvants, commensal bacteria-derived vesicles, anti-Leishmanial immunity, and immunodeficiency mechanisms. She collaborates with clinical immunologists to study disease pathogenesis in primary immunodeficiencies. Education: Postdoc: FDA/NIH, Bethesda, USA (1998-2002) Ph.D.: University College London, School of Pharmacy, UK (1993-1996) M.Sc.: METU, Biological Sciences, Turkey (1987-1990) B.Sc.: METU, Biological Sciences, Turkey (1983-1987) Research Interests: Her work bridges immunology and molecular biology, emphasizing vaccine development, microbiome interactions, and immune dysfunction analysis. Key topics include PRR-ligand adjuvants, exosome-based therapies, and microbiota in spinal cord injury patients. Publications: Her articles highlight advancements in vaccine adjuvant nanotechnology (Sci Transl Med, 2014), microbiota-immune interactions (PLoS One, 2016), and NETosis mechanisms in genetic immunodeficiencies (JACI, 2018).

Xian-Ming Chenمشاهده پروفایل

استاد

• Microbial Pathogenesis
• Mucosal Immunity
• Infectious Diseases
• +۶ مورد دیگر

Xian-Ming Chen, MD is a Professor in the Department of Microbial Pathogens and Immunity at Rush Medical College, Rush University Medical Center. His research laboratory focuses on mucosal immunity and microbial pathogenesis, particularly investigating how epithelial cells defend against pathogens at gastrointestinal, respiratory, and urogenital interfaces. Dr. Chen's research program centers on understanding the role of non-coding RNAs (ncRNAs), especially long ncRNAs (lncRNAs), in regulating mucosal immune responses. His work explores how pattern recognition receptors (PRRs) and NF-ĸB signaling pathways orchestrate antimicrobial defense in epithelial cells, with particular emphasis on host-pathogen interactions involving Cryptosporidium . His laboratory employs advanced techniques including RNA-DNA and RNA-protein interaction assessments, 3D enteroid models, and exosome analysis to investigate how mucosal inflammation links to infectious diseases and tumorigenesis. Investigating PRR-responsive lncRNAs in inflammatory and defense responses Studying molecular mechanisms of Cryptosporidium infection in immunocompromised patients Examining epigenetic modifications linking chronic inflammation to cancer development Dr. Chen currently leads four active NIH-funded projects including R01-AI116323-07 on intestinal cryptosporidiosis and R01-AI136877-04 on LincRNAs in mucosal defense against AIDS opportunistic pathogens. His laboratory team includes Research Scientist Ai-Yu Gong, MD, MS and PhD Candidates Chansorena Pok and Shuhong Wang. Previous research has been supported by multiple NIH grants including U01-AI095532 on epithelial exosomes and TLR-mediated mucosal defense, and R01-AI071321 on microRNAs in epithelial innate immunity.