جست‌وجوی استاد و پژوهشگر

Alexander Gitlinمشاهده پروفایل

استادیار

• Immunology
• Inflammation biology
• Innate immunity
• +۴ مورد دیگر

Alexander Gitlin, MD, PhD , is an Assistant Member in the Immunology Program of the Sloan Kettering Institute at Memorial Sloan Kettering Cancer Center , and an Adjunct Assistant Professor (by joint appointment) at the Weill Cornell Graduate School of Medical Sciences . He directs the Gitlin Lab, which investigates how inflammatory cell signaling controls the magnitude and quality of innate immune responses in health and disease. Education & Training AB, Chemistry & Physics – Harvard University, 2009 PhD, Immunology – The Rockefeller University, 2016 (mentor: Michel Nussenzweig) MD – Weill Cornell Medicine, 2017 Residency, Clinical Pathology – Stanford University, 2017-2019 Post-doctoral training – Genentech, Inc. (Vishva Dixit laboratory), 2019-2022 Research Focus The Gitlin Lab combines genome-editing , proteomics , advanced imaging , and in-vivo models to dissect molecular circuits that balance cell survival and death during innate immune activation. By studying genes mutated in inherited autoinflammatory diseases, the group aims to uncover new therapeutic targets for immunodeficiency, auto-inflammation and cancer. Representative Publications Trend Across 25 peer-reviewed articles (2011-2025), Gitlin’s work moves from foundational studies on germinal-center B cell selection to recent high-impact papers that mechanistically link ubiquitin signaling, caspase activity and Toll-like receptor pathways. These studies collectively illuminate how post-translational modifications tune inflammatory intensity. Scientific Awards & Honors Pershing Square Sohn Cancer Prize – 2025 NIH Director’s DP5 Early Independence Award – 2022-2027 Josie Robertson Investigator – 2022-2027 Burroughs Wellcome Fund Career Award for Medical Scientists – 2022 NIAID K08 Mentored Clinical Scientist Award – 2021 Harold M. Weintraub Graduate Student Award – 2016 Training & Mentorship Gitlin currently mentors four PhD students (Kanno, Londoner, Morrison, Pacini) drawn from the Tri-Institutional and Gerstner Sloan Kettering programs. The lab hosts research fellows, technicians, and rotating students, and maintains active recruitment for fully-funded post-doctoral positions. Lab & Institutional Affiliations The Gitlin Lab is physically housed within the Immunology Program at the Sloan Kettering Institute, with access to core facilities for CRISPR editing, single-cell genomics, high-resolution imaging and mouse models. The group is additionally affiliated with the Gerstner Sloan Kettering Graduate School of Biomedical Sciences and the Weill Cornell Immunology & Microbial Pathogenesis PhD program .

Chun-Jun (CJ) Guoمشاهده پروفایل

دانشیار

• Microbiome
• Molecular Mechanisms
• Metabolomics
• +۴ مورد دیگر

Chun-Jun (CJ) Guo is an Associate Professor at Weill Cornell Medicine's Jill Roberts Institute for Research in Inflammatory Bowel Disease, Department of Medicine. His research focuses on developing genetic tools for human microbiota and investigating molecular mechanisms of host-microbe interactions related to IBD and metabolic diseases. Education: B.Sc. in Pharmacy, Fudan University (2009) Ph.D. in Pharmacy, University of Southern California (2015) Research Interests: Dr. Guo's lab integrates bioinformatics, microbial genetics, metabolomics, and chemical biology to study how microbiota-derived molecules influence host immunity and disease. Key areas include CRISPR-based microbiota engineering, bile acid metabolism, and therapeutic reprogramming of host-microbe interactions. Publications: Recent work highlights microbiota-driven bile acid modifications in cancer, probiotic cross-feeding strategies for metabolic diseases, and serotonin's role in neonatal immune tolerance. His tools for genetic manipulation of nonmodel gut microbes enable mechanistic studies in vivo. Scientific Awards: 2023 Scialog Award 2022 Kenneth Rainin Foundation Innovator Award 2020 Noster & Science Microbiome Runner-Up Prize 2020 AGA-Allergan Pilot Award in IBD 2019 NIH New Innovator Award Labs & Teams: The Guo Group develops CRISPR-Cas9 systems for Clostridiales and other gut bacteria, investigates microbiota metabolites in preclinical mouse models, and collaborates on translational studies linking microbial genetics to immune/metabolic diseases.

Anthony Antonellisمشاهده پروفایل

استاد

• Transcriptional Regulation
• Genetic and Molecular Mechanisms of Mendelian Disease
• Aminoacyl-tRNA Synthetase Mutations
• +۳ مورد دیگر

Anthony Antonellis is a Professor of Human Genetics at the University of Michigan Medical School. His research focuses on transcriptional regulation and the genetic and molecular mechanisms of Mendelian disease, particularly mutations in aminoacyl-tRNA synthetases linked to neuropathies and neurodevelopmental defects. He is affiliated with the Antonellis Laboratory and the Cell and Molecular Biology (CMB) program. Implicit Bias Training Allayship Training Anti-Racism Training Disability Awareness Training Bystander Training Gender Bias/Discrimination Training Research areas include studies of gene regulation via cis-acting elements in myelinating cells, and the role of tRNA charging enzymes in neurodegenerative and developmental disorders. His group employs model organisms like yeast and zebrafish to explore clinical heterogeneity and disease mechanisms. Articles highlight Mendelian disorders, neuropathy genetics, tRNA synthetase dysfunction, and neurogenetics, with emphasis on translation to clinical diagnostics and therapeutics. Contact: antonell@umich.edu

Zhuhao Wuمشاهده پروفایل

استادیار

• Neuroscience
• Neurovascular Coupling
• Neural Circuit Mapping
• +۴ مورد دیگر

Zhuhao Wu serves as Assistant Professor of Neuroscience at the Brain and Mind Research Institute, Weill Cornell Medical College since 2022. His research integrates neurovascular biology, neural circuit mapping, and neurodegenerative mechanisms to understand brain organization and disease processes. Education: Ph.D. in Neuroscience, The Johns Hopkins University School of Medicine (2011) B.S. in Biological Sciences, Tsinghua University, China (2003) Research Focus: Dr. Wu pioneers multi-scale investigations of neurovascular coupling , brain-wide circuit organization , and neurodegenerative pathways . His lab employs whole-brain imaging , single-cell transcriptomics , and genetic engineering in murine models to dissect mechanisms of stroke recovery, tau pathology, and developmental disorders. Current work emphasizes regional blood-brain barrier heterogeneity and axon degeneration pathways with therapeutic implications. Publication Trends: Recent work (2023-2025) reveals three convergent themes: (1) neurovascular dynamics in health/disease, (2) high-resolution brain atlasing techniques, and (3) molecular mechanisms of neurodegeneration. Publications in Cell , Nature , and Neuron demonstrate methodological innovation in circuit mapping and translational relevance to stroke, Alzheimer's, and autism spectrum disorders. Grant Portfolio: Principal Investigator Subaward: NINDS R01 Investigating Neurobiology of Early Cognitive Impairment (2024-2029) Principal Investigator Subaward: NINDS R01 Mechanisms of anosmia in COVID-19 (2023-2028) Principal Investigator Subaward: NINDS BRAIN CONNECTS Center for Large-scale Imaging (2023-2028) Principal Investigator Subaward: NINDS Global mapping of DDX3X mutation circuits (2023-2028) Principal Investigator Subaward: NIAID single-cell encephalitis pathogenesis (2023-2026) Dr. Wu leads a multidisciplinary team within the Brain and Mind Research Institute focused on developing HOLiS (whole-brain staining/clearing pipeline) and TrailMap for neural circuit analysis. His lab collaborates extensively on NIH BRAIN Initiative projects advancing large-scale connectome mapping.

Maureen A. Sartorمشاهده پروفایل

استاد

• Bioinformatics
• Epigenomics
• Cancer Research
• +۴ مورد دیگر

Maureen A. Sartor is a Professor in the Department of Computational Medicine and Bioinformatics at the University of Michigan Medical School, with a joint appointment in Biostatistics at the School of Public Health. She serves as Co-Director of the Bioinformatics Graduate Program and leads an active research laboratory focused on computational biology. Education: PhD in Biostatistics, University of Cincinnati (2007) MS in Biomathematics, North Carolina State University (2000) BS in Mathematics with minors in Biology and Computer Science, Xavier University (1998) Research Focus: Dr. Sartor develops bioinformatics methods for analyzing high-throughput regulatory and epigenomic data. Her primary research examines cancer epigenomics and biomarker discovery in oral squamous cell carcinomas, with additional projects on ALS pathogenesis and computational methods for predicting chemical exposure-gene interactions. Her lab specializes in multi-omics analyses and tool development for genomic data interpretation. Publication Trends: Her recent work (2016-2022) demonstrates strong emphasis on HPV-related head/neck cancer biology, epigenetic regulation mechanisms (DNA methylation/hydroxymethylation), and development of bioinformatics tools for genomic region annotation and enrichment analysis. Publications consistently integrate computational method development with translational cancer research applications. Student Advising: Actively mentors graduate students across bioinformatics, biostatistics, and cancer biology programs. Current advisees include 8 PhD candidates and 1 MS student. Previously advised 6 PhD graduates now working in academia and industry. Laboratory Leadership: Directs the Sartor Lab emphasizing collaborative science and Michigan Medicine's core values (Caring, Integrity, Teamwork, Innovation). Research activities focus on cancer epigenomics, HPV oncology, and bioinformatics tool development for the research community.

• Preterm Birth
• Myometrial Function
• Reproductive Biology
• +۴ مورد دیگر

Craig Ulrich, Ph.D., serves as a Research Assistant Professor in the Department of Pharmacology at the University of Nevada, Reno, where he investigates mechanisms of spontaneous preterm labor using innovative 3D tissue models and proteomic approaches to address neonatal health disparities. His educational background includes: B.S. in Cell and Molecular Biology from the University of Washington, Seattle Ph.D. in Biochemistry from the University of Nevada, Reno Dr. Ulrich's research centers on myometrial functionality during pregnancy, with emphasis on how endogenous and exogenous compounds (including cannabinoids) regulate birth timing. His lab pioneered a 3D-printed uterine tissue model that responds to physiological stimuli, enabling precise study of contractile mechanisms. Key areas include S-nitrosoproteome dynamics , matrix metalloproteinase regulation , and obesity-related cardiac impacts on pregnancy outcomes. Analysis of his publications (2008-2025) reveals an evolution from foundational nitric oxide signaling studies toward translational 3D tissue engineering and matrix metalloproteinase-focused preterm labor research. Recent work integrates proteomic network analysis with biomechanical modeling , demonstrating increasing emphasis on clinically actionable biomarkers for preterm birth prevention. Dr. Ulrich leads a research team developing advanced synthetic myometrial platforms for drug testing, with current projects examining prostaglandin-mediated contractions and acute matrix metalloproteinase effects using engineered tissue systems.

Kevin Zwezdarykمشاهده پروفایل

استادیار

• Cytomegalovirus
• Mitochondria
• Metabolism
• +۶ مورد دیگر

Kevin Zwezdaryk, PhD is an Assistant Professor in the Department of Microbiology and Immunology at Tulane University School of Medicine. He received his BS from Nicholls State University, followed by PhD and Postdoctoral training at Tulane University in Biochemistry/Molecular Biology and Microbiology/Immunology. Education: BS (Nicholls State University), PhD (Tulane University), Postdoc (Tulane University) His research focuses on how human cytomegalovirus (HCMV) manipulates host metabolic pathways, particularly mitochondria, to facilitate viral replication and its implications for aging and cancer. His work investigates HCMV-induced alterations in ATP production, reactive oxygen species, nuclear signaling, and apoptosis. Key research areas include: Host-virus metabolic interactions Mitochondrial dysfunction in viral pathogenesis Applications to aging and oncology Development of antiviral strategies targeting host metabolism Recent publications highlight his work on metabolic diagnostics, neuroinflammation in viral infections, and immunometabolism. His lab utilizes advanced techniques like Seahorse metabolic analysis and CRISPR-based diagnostics.

Axel Skyttheمشاهده پروفایل

پژوهشگر

• Medical demography
• Genetic epidemiology
• Twin studies
• +۸ مورد دیگر

Axel Skytthe is a researcher at the University of Southern Denmark with a focus on Epidemiology, Biostatistics and Biodemography (EBB) . His research spans medical demography , genetic epidemiology , twin studies , and aging . He is affiliated with the Danish Center for Twin Research and the Institute for Health Services Research . Research Interests : Axel’s work primarily investigates genetic and environmental influences on aging, disease susceptibility, and mortality through large-scale twin cohorts. His studies often intersect with genetics , biostatistics , and demographic trends . Recent projects include analyzing BMI development across early life stages and exploring mTOR pathway epigenetics in tic disorders. Publications : His extensive body of work (203 publications) includes groundbreaking twin studies on respiratory syncytial virus , tic comorbidities , and exceptional lifespans . Collaborative research spans 25 twin cohorts globally, highlighting genetic determinism and environmental interactions. Professional Activities : Axel has participated in major conferences like the 15th International Society for Twin Studies Congress (2014) and European Congress of Epidemiology (2013). He is also a peer reviewer and board member in several organizations.

Daniel Hawigerمشاهده پروفایل

استاد

• Dendritic Cell Biology
• T Cell Immunology
• Immunomodulation
• +۵ مورد دیگر

Daniel Hawiger is a Professor at the School of Medicine , Saint Louis University , specializing in the Department of Molecular Microbiology and Immunology . With a career spanning both clinical and basic science research, he has made seminal contributions to immunology through his work on dendritic cells, T cells, and immunomodulation strategies.

Caetano Antunesمشاهده پروفایل

استادیار

• Microbiology
• Host-Microbe Interactions
• Gut Microbiome
• +۳ مورد دیگر

Caetano Antunes is an Assistant Professor in the Department of Molecular Biosciences at the University of Kansas, where he joined in January 2023 after transitioning from Fundação Oswaldo Cruz in Rio de Janeiro, Brazil. His research program focuses on host-microbe interactions with particular emphasis on small molecules in the gut metabolome and their effects on bacterial pathogen behavior. Dr. Antunes earned his B.Sc. and M.Sc. in Microbiology from Universidade Federal do Rio de Janeiro (2000, 2002), completed his Ph.D. at the University of Iowa (2007), and conducted post-doctoral research at the University of British Columbia (2008-2012). His work bridges microbiology, metabolomics, and molecular biology to understand how microbial metabolites influence pathogen virulence and host responses. His recent publications reveal a consistent focus on gut microbiome-derived small molecules and their regulatory effects on bacterial pathogens like Salmonella and Vibrio cholerae. His research spans from basic molecular mechanisms to potential therapeutic applications targeting pathogen virulence without directly killing bacteria, representing a promising antivirulence approach to combat antibiotic resistance. Dr. Antunes teaches courses including Introduction to Honors Research, Immunology Laboratory, Rigor and Reproducibility in Research, and Advanced Molecular Genetics, demonstrating his commitment to training the next generation of scientists in both foundational and advanced molecular techniques.

Jennifer E. Phillips-Creminsمشاهده پروفایل

دانشیار

• 3D Genome Organization
• Chromatin Biology
• Neurogenetics
• +۵ مورد دیگر

Jennifer E. Phillips-Cremins, Ph.D. , is an Associate Professor of Genetics and Bioengineering at the University of Pennsylvania, where she leads the Laboratory of Chromatin and Spatial Neurobiology. A member of the Penn Epigenetics Institute and NIH 4D Nucleome Consortium, her research investigates how three-dimensional chromatin organization governs neural specification, synaptic plasticity, and disease pathogenesis. Her lab integrates 3D genome mapping, single-cell imaging, and computational tools to dissect chromatin-synapse communication in Alzheimer's disease, fragile X syndrome, and schizophrenia. Education : B.S. in Chemical Engineering (Clarkson University, 1999), Ph.D. in Biomedical Engineering (Georgia Tech, 2007) Postdoctoral Training : University of Massachusetts (Dekker Lab) and Emory University (Corces Lab, 2008-2013) Her lab has developed groundbreaking technologies including LADL for optogenetic chromatin control, FISHnet for single-cell spatial genomics, and MASTR-seq for repeat expansion analysis. Key discoveries demonstrate that cohesin-mediated loops regulate replication origins and synaptic gene expression, while BREACHes link repeat instability to neurodevelopmental defects. Scientific Recognition : NIH Pioneer Award (2021) NSF CAREER Award (2020) Chan-Zuckerberg Neurodegenerative Disease Awardee (2020) New York Stem Cell Foundation Robertson Investigator (2015-2020) Mentorship : Creator of the SEEDs program for undergraduate/post-baccalaureate training, with 100% of alumni pursuing advanced scientific degrees. Her lab currently trains 3 SEEDs scholars and advises graduate students in Cell and Molecular Biology, Neuroscience, and Bioengineering programs.

• Pigmentary Disorders
• Skin of Color
• Dermatology
• +۳ مورد دیگر

Dr. Nisma Mujahid serves as a Clinical Assistant Professor in the Department of Dermatology at the University of Utah, providing specialized care at University of Utah Hospital and Stansbury Health Center. Her clinical expertise centers on pigmentary disorders in diverse populations, with strong commitment to medical education and research. Her academic foundation includes: MD, PhD from Boston University School of Medicine Dermatology Residency at University of Utah Spencer Fox Eccles School of Medicine Internal Medicine Internship at University of Florida B.S. in Biochemistry and Pre-Medicine from Mississippi State University Dr. Mujahid's research critically examines pigmentary disorders including vitiligo and lichen planus pigmentosa, with specialized focus on skin of color and multi-ethnic dermatology . Her work bridges clinical practice and translational science, addressing therapeutic gaps in conditions affecting underrepresented populations while investigating systemic issues like gender representation in academic dermatology. Analysis of her publication record reveals three dominant research trajectories: molecular mechanisms of pigmentation (particularly UV-independent pathways), clinical interventions for scarring disorders, and health equity studies. Her interdisciplinary approach spans human dermatology, veterinary comparative models, and evidence-based procedural reviews. No scientific awards were documented in the provided materials. She actively mentors dermatology residents and medical students, with patient feedback averaging 4.9/5 across 389 reviews highlighting her clinical thoroughness and patient-centered communication, though occasional notes mention scheduling challenges. Her educational leadership extends to curriculum development in pigmentary disorders and skin of color.

• Neurogenetics
• Neurodegenerative Diseases
• Mouse Models in Human Disease Research
• +۴ مورد دیگر

Professor Elizabeth Fisher is a leading academic in Neurogenetics at the UCL Queen Square Centre for Neuromuscular Diseases , affiliated with the Faculty of Brain Sciences at University College London. She specializes in mouse models for human neurodegenerative diseases. Undergraduate: Physiological Sciences, University of Oxford (1978–1981) PhD: Mouse Molecular Genetics, St Mary’s Hospital Medical School (Imperial College) and MRC Mammalian Genetics Unit (Harwell) (1983) Her research focuses on Down’s syndrome and amyotrophic lateral sclerosis (ALS) , using mouse models to investigate the neurological basis of these conditions. She collaborates extensively, including with Victor Tybulewicz since 1991. Recent publications highlight her work in neurogenetics , mouse modeling , and neurodegenerative disease mechanisms , including studies on ALS, Down syndrome, and metabolic alterations in genetically modified mice. Scientific recognitions include: Fellow of the Academy of Medical Sciences (2007) Member of EMBO (2009) Fellow of the Royal Society of Biology (2010) Wellcome Trust Senior Investigator (with Victor Tybulewicz) Her work emphasizes interdisciplinary collaboration and translational approaches, leveraging mouse genetics to address fundamental questions in neurodegeneration.

• Human Genetics
• Genetic Mapping
• Inherited Disorders
• +۷ مورد دیگر

Professor Tayfun Özçelik serves as Dean of the Faculty of Science at Bilkent University, where he chairs the Department of Molecular Biology and Genetics. A distinguished human geneticist, his career spans foundational work in identifying genes for inherited disorders and pioneering DNA identification in Turkish judiciary systems. He has led diagnostic genetics laboratories at both Istanbul and Bilkent Universities. 1986: MD, İstanbul University Medical School Postdoctoral: Physiology (Munich), Human Genetics (Yale), Howard Hughes Medical Institute (Stanford) His research focuses on molecular characterization of inherited disorders including Prader-Willi syndrome, Charcot-Marie-Tooth disease, and Parkinson’s. Current projects examine complex phenotypes like obesity and polycystic ovarian syndrome through genetic mapping and reverse phenotyping in consanguineous families. Recent work explores type I IFN immunity in severe COVID-19 cases. Key scientific contributions include discoveries of SNRPN for PWS, PMP22 for CMT1A, and HTRA2 for Parkinson’s. His lab also identified genes VLDLR , WDR81 , and ATP8A2 linked to cerebellar hypoplasia. Scientific Awards TÜBİTAK Young Investigator Award (1996) Bayındır Medical Award (2006) TÜBİTAK Science Award (2012) Dr. Özçelik has advised numerous graduate students and collaborates internationally, particularly with Rockefeller University. His work extends to X chromosome inactivation patterns in autoimmune diseases and establishing genomic medicine infrastructure in Turkey.

Helle F Jørgensenمشاهده پروفایل

دانشیار

• Vascular Biology
• Cardiovascular Disease
• Atherosclerosis
• +۵ مورد دیگر

Helle F Jørgensen is an Associate Professor at the University of Cambridge, based at the Victor Phillip Dahdaleh Heart and Lung Research Institute (VPD-HLRI). She is a Principal Investigator in the Cardiovascular and Respiratory Medicine (CaRM) section of the Department of Medicine and a key member of the Cambridge Cardiovascular Interdisciplinary Research Centre and the British Heart Foundation (BHF) Cambridge Centre of Excellence. Dr. Jørgensen earned her PhD in molecular biology from Aarhus University in 2000 under Professor Brian Clarke. Her postdoctoral training included research on DNA-methylation-binding factors with Professor Sir Adrian Bird at the University of Edinburgh and investigations into transcription factors and epigenetic mechanisms in embryonic stem cell maintenance with Professor Dame Amanda G Fisher at the London Institute of Medical Research. Her research focuses on vascular smooth muscle cell (VSMC) plasticity and heterogeneity in vascular health and disease. She has demonstrated that a small number of pre-existing VSMCs undergo extensive proliferative expansion to generate the majority of cells in atherosclerotic lesions, with similar clonal expansion observed in other vascular disease models. Using single-cell transcriptome profiling, her group has revealed substantial VSMC heterogeneity both in lesions and healthy arteries. This work has significant implications for understanding VSMC behavior and developing selective targeting strategies for disease-associated VSMCs. Her laboratory employs single-cell approaches, lineage tracing, and global epigenetic profiling to study how gene expression programs are regulated and impact phenotypic plasticity in genetic disease models and human tissue. They investigate how VSMCs contribute to atherosclerosis development, the disease underlying heart attack and stroke, with focus on how these cells downregulate their contractile phenotype in response to injury and inflammation. British Heart Foundation Senior Basic Science Research Fellow Dr. Jørgensen's work has important translational implications for cardiovascular medicine. Her research on VSMC heterogeneity and clonal expansion provides critical insights into atherosclerosis pathogenesis and identifies potential therapeutic targets. As part of the BHF Cambridge Centre of Excellence, her research contributes to the broader mission of improving cardiovascular and lung health worldwide through collaborative research across university, NHS, commercial, and charitable sectors. The Jorgensen Group operates within the Victor Phillip Dahdaleh Heart and Lung Research Institute, a state-of-the-art facility that brings together researchers and clinicians to advance understanding of cardiovascular and respiratory diseases. Her work bridges fundamental molecular mechanisms with clinical applications in vascular medicine.