جستجوی استاد راهنمای دانشگاهی

Todd Squiresمشاهده پروفایل

استاد

• Fluid Mechanics
• Transport Science
• Microfluidics
• +۷ مورد دیگر

Professor Todd Squires is a distinguished faculty member in the Department of Chemical Engineering at the University of California, Santa Barbara, within the Robert Mehrabian College of Engineering. His research focuses on the fundamental principles of transport phenomena as applied to interfaces, membranes, and complex fluids, employing theoretical, computational, and experimental approaches to address significant challenges in micro-scale fluid mechanics. Dr. Squires' educational background includes: BS in Physics, UCLA (1995) BA in Russian Language and Literature, UCLA (1995) PhD in Physics, Harvard University (2002) His research interests span microfluidics and electrokinetics, active and nonlinear microrheology of complex materials, polymer dynamics and sensors, with particular emphasis on non-linear electrokinetic flows, interfacial rheology, and the self-assembly of nanostructured materials. His work bridges fundamental fluid mechanics with practical applications in microfluidic devices, energy storage, and biomedical systems, demonstrating the versatility of this fascinating field. Analysis of Professor Squires' recent publications reveals a consistent focus on interfacial phenomena, with particular attention to the rheological properties of fluid interfaces, particle dynamics in complex fluids, and novel microfluidic techniques for measuring and manipulating these systems. His research demonstrates strong interdisciplinary connections between chemical engineering, physics, and materials science, with applications spanning energy storage, biomedical engineering, and environmental systems. Professor Squires has received numerous prestigious awards and honors: 2018 Robert W. Vaughan Lecture in Chemical Engineering, Caltech 2015 Elected Fellow of the American Physical Society 2013 Mid-Career Award, American Electrophoresis Society 2012 The Dudley Saville Memorial Lecture at Princeton 2010 Pierre Gilles de Gennes Prize 2010 Allan P. Colburn Memorial Lectureship, University of Delaware 2009 Francois Frenkiel Award for Fluid Mechanics 2009 Camille Dreyfus Teacher-Scholar Award 2008 Beckman Young Investigator 2007 NSF CAREER Award 2005 'Rising Star' - Chronicle of Higher Education As principal investigator of the Squires Group, Professor Squires leads a dynamic research team that combines experimental, theoretical, and computational approaches to investigate transport phenomena at interfaces. His work has been supported by major funding agencies including the National Science Foundation, with his CAREER award indicating early recognition of his potential as both researcher and educator. While specific grant details aren't provided in the source material, his extensive publication record and prestigious awards suggest robust and sustained research funding. The Squires Group maintains state-of-the-art laboratory facilities for studying micro-scale fluid mechanics, including specialized equipment for microrheology measurements, microfluidic device fabrication, and interfacial characterization. Their research environment fosters collaboration across disciplines, with connections to materials science, physics, and biomedical engineering researchers at UCSB and beyond.

• Protein Degradation Pathways
• Ubiquitin-Proteasome System
• Pendrin Mutations
• +۲ مورد دیگر

Florian Huber is a Research Associate at Paracelsus Medical University's Institute of Pharmacology and Toxicology, investigating molecular mechanisms of genetic hearing disorders. His work focuses on ubiquitin-proteasome regulation of pendrin (SLC26A4) variants associated with Pendred syndrome. Recent studies demonstrate how proteasome inhibitors rescue function of pathogenic pendrin mutants, offering therapeutic pathways for hearing restoration. Huber develops experimental and computational approaches to map degradation pathways of membrane transport proteins. He supervises medical doctoral candidates and teaches pharmacology in graduate programs.

Andrew Spakowitzمشاهده پروفایل

استاد

• Chromosomal organization and dynamics
• Protein self-assembly
• Polymer membranes
• +۷ مورد دیگر

Andrew Spakowitz is a Professor of Chemical Engineering, Materials Science and Engineering, and by courtesy, Applied Physics and Chemistry at Stanford University. He currently serves as the Senior Associate Dean for Research and Faculty Affairs and holds the Tang Family Foundation Chair of the Department of Chemical Engineering. His academic career at Stanford spans from Assistant Professor (2006-2014) to Associate Professor (2014-2020) and now Professor since 2020. Dr. Spakowitz earned his PhD in 2004, MS in 2001 from the California Institute of Technology, and his BS in Chemical Engineering from the University of Wisconsin, Madison in 1999. He completed postdoctoral training in Molecular and Cell Biology and Biophysics at UC Berkeley from 2004-2006. His research focuses on theoretical and computational approaches to understanding biological processes and complex materials. The Spakowitz lab addresses fundamental chemical and physical phenomena through four main research themes: chromosomal organization and dynamics, protein self-assembly, polymer membranes, and charge transport in conducting polymers. His group employs diverse theoretical and computational methods including analytical theory of semiflexible polymers, polymer field theory, continuum elastic mechanics, Brownian dynamics simulation, equilibrium and dynamic Monte Carlo simulations, and reaction-diffusion modeling. Analysis of his recent publications reveals a strong emphasis on epigenetics and chromatin dynamics, with significant work on DNA methylation patterns, nucleosome clustering, and chromosome organization. His research also extends to polymer physics applications in biological systems, particularly in respiratory diseases, water purification membranes, and bacterial phage interactions with human mucus. Tang Family Foundation Chair of the Department of Chemical Engineering Professor Spakowitz mentors several graduate students and postdoctoral scholars in the Chemical Engineering and Materials Science departments. His lab members work on diverse projects spanning from chromatin dynamics to polymer membranes for water purification. He teaches multiple courses including CHEMENG 120B (Energy and Mass Transport), CHEMENG 340 (Molecular Thermodynamics), CHEMENG 466 (Polymer Physics), and CHEMENG 467 (Physics of Biomacromolecules). The Spakowitz lab operates from Clark S295 at Stanford University, conducting theoretical and computational research that bridges chemistry, physics, biology, and engineering disciplines to address complex problems across multiple length and time scales.

Dewey G. McCaffertyمشاهده پروفایل

استاد

• Chemical Biology
• Chromatin Modification
• Enzymology
• +۳ مورد دیگر

Dewey G. McCafferty is Professor of Chemistry at Duke University with appointments in Biochemistry and the Duke Cancer Institute. His research focuses on chemical biology of chromatin-modifying enzymes and ubiquitin signaling pathways relevant to neurodegeneration and infection. Notable work includes discovering the lasso peptide antibiotic Arcumycin, characterizing the Nedd4 ubiquitin ligase in Parkinson's disease models, and developing chemoproteomic approaches for target identification. Key contributions include elucidation of the futalosine pathway in Chlamydia infections, mechanisms of CPAF protease in bacterial pathogenesis, and engineering of histone demethylase enzymes. McCafferty received the Eli Lilly Award in Biological Chemistry (2005) and directs NIH-funded projects on ubiquitin ligases in neurodegeneration.

Patricia Championمشاهده پروفایل

استاد

• Molecular Genetics
• Mycobacterial Pathogenesis
• Bacterial Genetics
• +۷ مورد دیگر

Patricia Champion is a Professor in the Department of Biological Sciences at the University of Notre Dame, where she holds the title of Notre Dame Collegiate Professor. Her research is centered on the molecular mechanisms of mycobacterial pathogenesis, with a focus on protein transport and virulence. She is affiliated with the Eck Institute for Global Health and the Center for Rare and Neglected Diseases. PhD in Molecular Biology, Princeton University (2003) B.S. in Biological Sciences, Carnegie Mellon University (1998) Her research interests lie in understanding how pathogenic mycobacteria, including Mycobacterium tuberculosis and M. marinum , cause disease through targeted protein secretion, particularly via the Type VII (ESX-1) secretion system. She investigates how secreted proteins function as effectors and regulate gene expression, and how post-translational modifications like acetylation influence virulence. Her lab employs an interdisciplinary approach combining genetics, molecular biology, proteomics, and transcriptomics. The recent publications highlight a strong focus on ESX-1-mediated secretion, identification of novel substrates, regulatory mechanisms (e.g., WhiB6, EspM), and post-translational modifications. The work spans fundamental bacterial physiology to host-pathogen interactions, contributing to the broader goal of identifying targets for anti-virulence therapeutics against tuberculosis. Her scientific recognition includes being named a Notre Dame Collegiate Professor, a distinguished honor reflecting her scholarly excellence. Dr. Champion leads an active research laboratory committed to fostering an inclusive and respectful environment, emphasizing core values such as integrity, teamwork, and excellence. Her lab's work is supported by ongoing research grants, though specific funding sources are not detailed in the text. The Champion Lab operates within the Department of Biological Sciences and collaborates with key institutes at Notre Dame focused on global and neglected diseases.

Matthias Mannمشاهده پروفایل

استاد

• Mass Spectrometry
• Proteomics
• Systems Biology
• +۶ مورد دیگر

Professor Matthias Mann is a world-leading scientist serving as Director of the Proteomics and Signal Transduction department at the Max Planck Institute of Biochemistry in Martinsried, Germany, and Director of the Proteomics department at the Novo Nordisk Foundation Center for Protein Research, Faculty of Health Sciences, University of Copenhagen, Denmark. With an h-index exceeding 277 and over 350,000 citations, he is recognized as the highest cited German researcher and one of the most influential scientists globally in proteomics. His educational background includes: Ph.D. in Chemical Engineering from Yale University (1988) Master's Degree in Physics from Georg August University Göttingen (1984) Bachelor's of Arts in Mathematics from Georg August University Göttingen (1982) Professor Mann's research focuses on advancing mass spectrometry-based proteomics to understand biological systems at the protein level. His work spans technological developments in mass spectrometry, bioinformatics and computational analysis, signal transduction and posttranslational modifications, and clinical proteomics applications for disease diagnosis and treatment. The Mann lab has pioneered groundbreaking methods like SILAC for quantitative proteomics and MaxQuant for proteome data analysis. Their vision is to translate proteomics knowledge into clinical practice for predictive, diagnostic, and preventive medicine, with recent work focusing on AI-guided platforms for analyzing proteomes from minimal tissue samples. Analysis of Professor Mann's recent publications reveals a strong trend toward clinical applications of proteomics, particularly in cancer research, metabolic diseases, and neurodegenerative disorders. His work increasingly integrates spatial proteomics, single-cell resolution techniques, and artificial intelligence approaches to uncover disease mechanisms and identify potential biomarkers, with a clear shift from basic technology development toward direct clinical applications and personalized medicine. Professor Mann has received numerous prestigious awards throughout his career: 2025: Elected member of the American National Academy of Sciences 2024: Dr. H.P. Heineken Award for Biochemistry and Biophysics 2023: Otto Warburg Medal 2019: Nominated member of the Bavarian Academy of Sciences 2013: Elected member of Leopoldina German National Academy of Sciences 2012: Körber European Science Award, Louis-Jeantet Foundation Prize for Medicine, Ernst Schering Prize, and Leibniz Prize Professor Mann leads a highly collaborative research team involved in multiple international networks including the Bill & Melinda Gates Foundation, Michael J. Fox Foundation for Parkinson's Research, CLINSPECT-M, and Munich Heart Alliance. His lab has mentored numerous successful researchers, with several former postdocs receiving prestigious ERC Starting Grants. The Mann group has developed innovative clinical proteomics pipelines for analyzing archived tissue specimens and body fluids, aiming to identify protein markers for early detection of diseases such as diabetes and cancer. The Mann lab operates across two major research centers with state-of-the-art mass spectrometry facilities. Their Clinical Knowledge Graph platform integrates multi-omics data with extensive metadata, creating an ecosystem for machine learning applications in proteomics. Current research focuses on developing highly sensitive methods that can profile thousands of proteins from minimal cell samples, enabling the identification of critical disease-related proteins and supporting the development of individualized therapies.

Miyuki Hinoمشاهده پروفایل

استادیار

• Climate Change Adaptation
• Environmental Policy
• Disaster Risk Management
• +۳ مورد دیگر

Miyuki Hino is an Assistant Professor in the Department of City and Regional Planning and an Adjunct Assistant Professor in the Environment, Ecology, and Energy Program at the University of North Carolina at Chapel Hill. She holds a Ph.D. in Environment and Resources from Stanford University and a B.S. in Chemical Engineering from Yale University. Her research focuses on climate hazards, governance, and public policy , with emphasis on equitable adaptation to climate change. Key areas include sea level rise impacts, flood risk on property markets, and managed retreat strategies. She has conducted extensive work on floodplain development policies, household relocation programs, and community resilience frameworks. Dr. Hino's interdisciplinary approach integrates environmental science, urban planning, and social equity . She collaborates with academic and municipal partners, such as the Center for Urban and Regional Studies and Annapolis, MD local governments, to develop actionable solutions for climate adaptation. Her work bridges technical analyses (e.g., sensor networks, machine learning) with policy design to ensure both effectiveness and justice in climate responses. Recent projects emphasize preventing future 'trapped households' by analyzing zoning policies and market dynamics that drive risky development. She advocates for climate-smart growth strategies to balance economic needs with environmental safety, while addressing disparities in vulnerability across communities. Her research has been featured in Science Advances , Nature Climate Change , and interdisciplinary journals. She actively engages with policymakers to translate findings into practical measures, such as equitable buyout programs and floodplain management reforms.

• Environmental Science and Engineering
• Photocatalytic Materials
• Water Quality Engineering
• +۳ مورد دیگر

Jaehong Kim is the Henry P. Becton Sr. Professor of Engineering at Yale University, where he serves as Professor and Chair of Chemical and Environmental Engineering in the School of Engineering and Applied Science. Prior to joining Yale in 2013, he held the Georgia Power Distinguished Professor position at the Georgia Institute of Technology. His research bridges environmental science, chemical engineering, and nanotechnology, focusing on photocatalytic materials, water quality engineering, and sustainable solutions for global health contexts. Ph.D., Environmental Engineering, University of Illinois at Urbana-Champaign (2002) M.S., Chemical and Biological Engineering, Seoul National University (1997) B.S., Chemical and Biological Engineering, Seoul National University (1995) Kim’s work addresses water treatment through advanced oxidation processes , electrochemical systems , and single-atom catalysts , with applications in nitrate removal, fluoride transport, and solar disinfection. His research emphasizes nanotechnology for environmental remediation and public health engineering in developing regions. Recent publications highlight electrified membranes for nitrate conversion, photothermal water disinfection , and single-atom catalysts for pollutant degradation. His team explores atomic-scale engineering and green chemistry approaches to enhance reaction efficiency and material durability. Georgia Power Distinguished Professor Yale Superfund Research Center investigator Kim leads interdisciplinary efforts in environmental health through collaborations with Yale School of Public Health and the School of the Environment. His lab develops monolithic catalytic membranes and nanobiochars for sustainable water treatment, balancing technical innovation with global accessibility.

Waldemar Kolanusمشاهده پروفایل

استاد

• Molecular Immunology
• Cell Signaling
• Signal Transduction Pathways
• +۴ مورد دیگر

Prof. Waldemar Kolanus leads the Molecular Immunology and Cell Biology department at the University of Bonn's Life & Medical Sciences Institute (LIMES) . His research bridges immunoregulation , stem cell dynamics , and metabolic stress responses in immune cells. Unit 2 member at LIMES Principal investigator in SFB 704 and ImmunoSensation Cluster Leads a multidisciplinary lab with postdocs, PhD students, and technical staff His work focuses on intracellular signaling pathways connecting immune activation to tissue homeostasis, particularly through: Cytohesin proteins in integrin-mediated adhesion and migration TRIM71 in stem cell regulation and congenital hydrocephalus High-salt environments affecting macrophage function Publication trends show expertise in immune cell migration , genetic models , and chemical inhibition , with frequent use of mice and zebrafish for in vivo studies. Key articles explore: TRIM71's dual role in auditory development and germ cell maintenance Cytohesin family's Golgi regulation and insulin signaling Ruxolitinib's off-target migration inhibition of dendritic cells Contact details: Address: LIMES Institute, Carl-Troll-Straße 31, Bonn Email: kolanus.sekretariat@uni-bonn.de Phone: +49 228 73-62788

Martin Burkeمشاهده پروفایل

استاد

• Organic Chemistry
• Small-Molecule Synthesis
• Molecular Prosthetics
• +۷ مورد دیگر

Martin Burke is the May and Ving Lee Professor for Chemical Innovation and Professor of Chemistry at the University of Illinois Urbana-Champaign , with additional appointments in Biochemistry, Biomedical & Translational Sciences, and multiple campus institutes including the Beckman Institute and the Carl R. Woese Institute for Genomic Biology. Education B.S. Johns Hopkins University , 1998 Ph.D. Harvard University , 2003 M.D. Harvard Medical School , 2003 Research Interests Burke’s program centers on molecular prosthetics : the design, synthesis and application of small molecules that replicate or replace missing or dysfunctional proteins. His group pioneered iterative cross-coupling (ICC) using MIDA-protected haloboronic acids to automate the construction of complex natural products and function-oriented small molecules. Current projects target ion-channel replacement in cystic fibrosis, iron-transport restoration in anemia, and non-toxic antifungals that overcome drug resistance. Scientific Awards & Honors National Academy of Medicine (2021) AAAS Fellow (2021) ASCI Member (2021) iCON Award (2019) Mukaiyama Award, Japan (2019) ACS Nobel Laureate Award for Graduate Education (2017) Thieme-IUPAC Prize in Synthetic Organic Chemistry (2014) Elias J. Corey Award (2013) Arthur C. Cope Scholar Award (2011) Research Output & Impact Burke has authored >120 peer-reviewed articles, >30 patents, and his work has been cited >20,000 times. High-impact publications in Nature , Science , and Angewandte Chemie have advanced automated synthesis, molecular prosthetics, and cystic fibrosis therapeutics. Laboratory & Training The Burke Laboratories house a multidisciplinary team of graduate students, post-doctoral researchers, and physician-scientists developing next-generation molecular prosthetics. The group is supported by NIH, NSF, private foundations, and industry partnerships aimed at democratizing molecular innovation.

Jennifer L Clarkeمشاهده پروفایل

استاد

• Statistical Methodology
• Bioinformatics/Computational Biology
• Data Mining/Machine Learning
• +۳ مورد دیگر

Jennifer L. Clarke is a Professor in the Department of Statistics at the University of Nebraska–Lincoln and Director of the Quantitative Life Science Initiative. She holds leadership roles in enabling big data integration across the University of Nebraska system through collaborative research programs. Her affiliations include the Institute of Agriculture and Natural Resources (IANR) and the College of Agriculture and Natural Resources. Dr. Clarke's research focuses on statistical methodology for high-dimensional data, computational biology, bioinformatics, and bacterial genomics. Her work bridges statistical innovation with applications in oncology, microbiome analysis, and agricultural phenomics. Key areas include predictive modeling, machine learning, and genomic/metagenomic data integration. Her recent publications span cancer biomarker discovery, plant phenotyping methodologies, and microbial community analysis, reflecting her interdisciplinary approach. Articles emphasize translational applications like therapeutic target identification and precision agriculture. Dr. Clarke leads initiatives fostering collaboration between statisticians and domain scientists, including the Quantitative Life Science Initiative and contributions to the Agricultural Genome-to-Phenome Initiative (AG2PI). Her work advances data-driven solutions for healthcare and food security challenges. Notable projects include developing statistical tools for microbiome studies, analyzing root architecture via 3D imaging, and investigating cranberry-derived compounds' cancer-inhibitory mechanisms. Her methodological contributions include hybrid clustering techniques and predictive model validation frameworks.

• Mechatronics
• Dynamical Systems and Control
• Functional Printing
• +۴ مورد دیگر

George T.-C. Chiu is a Professor in the School of Mechanical Engineering at Purdue University, with courtesy appointments in Electrical and Computer Engineering and Psychological Sciences. He holds a 50% appointment as Assistant Dean for Global Engineering Programs and Partnerships. Previously, he served as a Program Director at the NSF, managing the Control Systems Program and National Robotics Initiative. His research focuses on mechatronics, dynamical systems, and control, with applications in printing, robotics, and human-machine interaction. Education: PhD (1994), University of California, Berkeley MS (1990), University of California, Berkeley BS (1985), National Taiwan University Research Interests: Functional printing technologies for biomedical and environmental sensors Robotics and human-robot interaction Control systems for manufacturing and dynamic systems Energy-efficient sensor design His work bridges mechanical engineering, materials science, and control theory, addressing challenges in precision manufacturing and sustainable technology. Awards: Fellow, ASME (2021) Fellow, Society for Imaging Science and Technology Grants & Projects: USDA-funded projects on food safety sensors and sustainable agriculture NSF initiatives in robotics and additive manufacturing Collaborative research with industry partners like HP and the Army Labs & Outreach: Founded the Purdue FIRST Programs, mentoring K-12 students in robotics. Co-developed experiential courses for student mentors, fostering leadership and project management skills.

Amit R. Reddiمشاهده پروفایل

استاد

• Biochemistry
• Metalloproteins in biological regulation and disease
• Heme trafficking and signaling
• +۴ مورد دیگر

Amit R. Reddi is a Professor at the Department of Chemistry, Georgia Institute of Technology. His research focuses on metalloproteins, particularly the mechanisms of heme trafficking and redox signaling in relation to cancer, neurodegenerative disorders, and infectious diseases. He has received numerous awards for both research and teaching excellence. Education : B.A. from Carleton College (2003) Ph.D. from Columbia University (2008) NIH Postdoctoral Fellowship at Johns Hopkins University (2013) Research Interests : The Reddi laboratory investigates cellular mechanisms of metalloprotein activation and inter-biomolecular communication in metabolic and signaling pathways critical to human health. Key projects explore heme trafficking pathways and the role of Cu/Zn Superoxide Dismutase (SOD1) in redox signaling, with implications for cancer, neurodegenerative diseases, and microbial pathogenesis. Scientific Awards : Vasser Woolley Faculty Fellowship (2021) Student Recognition of Excellence in Teaching Class of 1934 Award (2021) CTL/BP Junior Faculty Excellence in Teaching Award (2019) Bergmann Memorial Award (2018) Blanchard Professorship (2016) NSF CAREER Award (2015) NIH NRSA Post-doctoral Fellowship (2008-2011) Grants & Fellowships : NSF CAREER Award (2015) Sigma Xi Grants-In-Aid-of-Research (2003) NIH Cancer Research Training Award Fellowship (1999-2001)

Jing Wangمشاهده پروفایل

استاد

• Air Pollution Control
• Nanoparticle Transport
• Emission Reduction
• +۴ مورد دیگر

Prof. Dr. Jing Wang is a Full Professor at the Department of Civil, Environmental and Geomatic Engineering at ETH Zürich. His research focuses on air pollution control, nanoparticle transport, and environmental health and safety (EHS) impacts of nanomaterials. He has held roles including Assistant Professor at ETH Zürich (2010–present), Research Assistant Professor at the University of Minnesota (2007–2010), and postdoctoral associate in Particle Technology (2005–2007). Education: Bachelor’s in Engineering (2000) – Tsinghua University, Beijing Master’s in Computer Sciences (2003) – University of Minnesota PhD in Aerospace Engineering (2005) – University of Minnesota Research Interests: Air/water filtration technologies Nanoparticle emission reduction and measurement Multiphase flow mechanics Environmental impacts of nanomaterials Collaborations: Industrial partnerships include 3M, BASF, Boeing, Intel, Samsung, and others in nanoparticle measurement and filtration solutions. Honors: 2011 Smoluchowski Award (Association for Aerosol Research) 2006 ‘Best Dissertation’ Award (University of Minnesota) 2004 Doctoral Dissertation Fellowship Teaching: Courses include Air Pollution Control, Environmental Engineering Seminars, and Excursions for Environmental Engineers. Labs/Teams: Leads the Particle Technology Lab and collaborates with the Institute of Environmental Engineering at ETH Zürich.

Masato Katoمشاهده پروفایل

استاد

• Protein Phase Separation
• Low-Complexity Domains
• RNA Granule Biogenesis
• +۳ مورد دیگر

Masato Kato serves as Professor in the Department of Biochemistry at the University of Texas Southwestern Medical Center since 2020 and concurrently as Team Leader at Japan's National Institutes for Quantum and Radiological Science and Technology. His academic trajectory includes progressive appointments from Assistant Professor (2004-2014) to Associate Professor (2014-2020) at UT Southwestern, with prior postdoctoral training at Harvard Medical School and Nara Institute of Science and Technology. 2020-present: Professor, Department of Biochemistry, UT Southwestern 2020-present: Team Leader, National Institutes for Quantum and Radiological Science and Technology, Japan 2014-2020: Associate Professor, Department of Biochemistry, UT Southwestern 2010-2014: Assistant Professor, Department of Biochemistry and Internal Medicine, UT Southwestern 2004-2010: Assistant Professor, Department of Internal Medicine, UT Southwestern 1999-2004: Postdoctoral Fellow, Ellenberger Lab, Harvard Medical School 1998-1999: Postdoctoral Fellow, Hakoshima Lab, Nara Institute of Science and Technology Dr. Kato's research pioneers the biophysical characterization of protein phase separation, particularly focusing on low-complexity domains (LCDs) in neurodegenerative disease contexts. His work establishes fundamental mechanisms of biomolecular condensate formation, including hydrogel polymerization, liquid-solid transitions, and mutation-induced dysregulation in ALS/FTD. Key contributions demonstrate how C9orf72-encoded poly-dipeptides disrupt nucleocytoplasmic transport and how redox states regulate Ataxin-2 phase behavior, bridging structural biochemistry with pathological mechanisms. Analysis of his 22 publications reveals a cohesive research program centered on LCD-driven phase transitions. The most recent 15 articles (2012-2019) systematically investigate pathological aggregation in neurodegeneration, structural basis of condensate formation, and regulatory mechanisms like phosphorylation and oxidation. This body of work establishes LCDs as central players in both physiological RNA granule assembly and disease-associated solidification, with strong emphasis on C9orf72-related ALS/FTD mechanisms. Dr. Kato maintains active leadership within the McKnight Laboratory at UT Southwestern, where his team employs integrated approaches spanning structural biology, cell biology, and biophysics to dissect phase separation mechanisms. His collaborative network includes prominent neuroscience and biochemistry groups, with co-authorship on key studies in Cell, Science, and PNAS.