Christine Laryمشاهده پروفایل
پژوهشگر
- Statistical Genetics
- Bioinformatics
- Biostatistics
- +۷ مورد دیگر
Christine Lary is a Senior Biostatistician and Faculty Scientist I at the Center for Outcomes Research and Evaluation (CORE), MaineHealth Institute for Research, and is affiliated with the Graduate School of Biomedical Science and Engineering at the University of Maine. She earned her Ph.D. in Bioinformatics with a co-major in Statistics from North Carolina State University, an M.S. in Biomedical Engineering from Duke University, and a B.S. in Engineering Physics from Cornell University. Prior to joining CORE in 2012, she served as an Assistant Professor of Biostatistics at the University of Alabama at Birmingham. Ph.D., Bioinformatics (co-major in Statistics), North Carolina State University, 2009 M.S., Biomedical Engineering, Duke University, 1999 B.S., Engineering Physics, Cornell University, 1996 Dr. Lary’s research is centered on statistical genetics, bioinformatics, clinical prediction models, and data mining. Her work integrates large-scale genomic and clinical data to uncover mechanisms linking bone health, cardiovascular disease, and neurodegeneration. She employs advanced statistical methods, including Mendelian randomization and network analysis, to explore associations between bone mineral density and dementia, pharmacogenomic effects of beta-blockers, and disease co-occurrence patterns in cancer and cardiovascular conditions. Her recent publications highlight a strong focus on the intersection of bone and brain health, pharmacogenomics, and translational biostatistics. Themes include the impact of beta-blockers on bone density, shared molecular pathways between osteoporosis and Alzheimer’s disease, and risk prediction in geriatric populations. Her methodological expertise spans longitudinal modeling, meta-analysis, and systems biology approaches. Dr. Lary actively collaborates with clinical investigators at the University of Alabama at Birmingham Comprehensive Cancer Center and provides biostatistical consulting and research design support across MHIR. She has contributed to numerous high-impact studies in journals such as Journal of Bone and Mineral Research , JAMA Network Open , and Nature Metabolism . Extensive collaborations with MHIR and UAB Comprehensive Cancer Center Biostatistical consulting for clinical and translational research Research design and analytic support for multidisciplinary teams She is a key contributor to interdisciplinary research teams investigating aging, chronic disease, and precision medicine. Her lab and collaborative networks focus on integrating multi-omics data with clinical outcomes to improve risk prediction and therapeutic strategies.
