جست‌وجوی استاد و پژوهشگر

Omar A. Salehمشاهده پروفایل

استاد

• Biophysics
• Soft Matter Physics
• Polymer Physics
• +۵ مورد دیگر

Professor Omar A. Saleh is a distinguished physicist and materials scientist at the University of California, Santa Barbara, holding appointments in both the Materials and Physics Departments. Since summer 2023, he has served as Chair of the Materials Department and maintains a minority appointment in the Biomolecular Science and Engineering (BMSE) Program, where he previously served as Director from 2013-2017. His educational background includes a B.S. in Physics from MIT (1997) and a Ph.D. in Physics from Princeton (2003), supported by a Hertz Fellowship. Following postdoctoral work at École Normale Supérieure in Paris developing single-molecule techniques for motor protein/DNA studies, he joined UCSB in 2005. Saleh's research centers on fundamental principles of biomolecular behavior through experimental investigation of biopolymer elasticity and biomimetic organelles. His lab pioneers precision single-molecule stretching experiments to study entropic/energetic contributions in soft systems and creates life-like behaviors using reconstituted nucleic acid/protein assemblies. Key focus areas include DNA nanostar phase separation, liquid-liquid phase behavior, intrinsically disordered proteins, and non-equilibrium biomolecular systems. His publication trends reveal a strong emphasis on biomolecular condensates (2023-2025), with recurring themes in DNA nanotechnology, polyelectrolyte physics, and single-molecule mechanics. Recent work explores tension-mediated control of phase separation, transcriptional regulation of biomolecular liquids, and active matter principles in DNA systems. NSF CAREER Award (2008) Bessel Research Award from Alexander von Humboldt Society (2017) Fellow of the American Physical Society (2019) Saleh actively mentors graduate students and postdocs including Sam Wilken, Gabrielle Abraham, Anna Nguyen, and Aria Chaderjian, whose research spans DNA nanostar liquids, active droplets, and complex coacervation. His lab develops innovative instrumentation including high-speed magnetic tweezers and GPU-based tracking systems, supported by grants such as NSF/MCB-BSF: Direct force measurements of intrinsically disordered proteins. The Saleh Group operates at BioE 3006, focusing on creating quantitative models of biological function through physical reconstitution.

Sriram Subramaniamمشاهده پروفایل

استاد

• cryo-electron microscopy
• structural biology
• drug-design
• +۴ مورد دیگر

Sriram Subramaniam is a Professor in the Department of Biochemistry and Molecular Biology at the University of British Columbia (UBC) and holds the Gobind Khorana Canada Excellence Research Chair in Precision Cancer Drug Design. His research leverages cryo-electron microscopy (cryo-EM) to advance structural biology and drug design, focusing on protein dynamics and therapeutic target identification. Education: PhD in Physical Chemistry (1987) from Stanford University; MSc in Chemistry (1981) from Indian Institute of Technology, Kanpur. Subramaniam's interdisciplinary work combines cryo-EM with computational tools and molecular biology to study protein structures at atomic resolution. His lab has pioneered cryo-EM applications in precision medicine, including mapping small molecule drugs on patient-specific cancer mutants. Recent publications (2024-2022) highlight his contributions to understanding SARS-CoV-2 immune evasion, structural mechanisms of ATPases, and AI integration in structural biology. His research spans viral entry mechanisms, CRISPR systems, and neurodegenerative disease pathways. Scientific Awards: Gobind Khorana Canada Excellence Research Chair NIH Director’s Award for Scientific Excellence Fellow of the Biophysical Society Breakthrough Prize nomination Based at the Djavad Mowafaghian Center for Brain Health, Subramaniam leads the Program in Cryo-EM Guided Drug Design, contributing to over 177 peer-reviewed publications with a career h-index of 58 and citations exceeding 12,340.

Björn Corziliusمشاهده پروفایل

استاد

• Solid-state NMR Spectroscopy
• Dynamic Nuclear Polarization (DNP)
• Biomolecular Chemistry
• +۳ مورد دیگر

Prof. Dr. Björn Corzilius is a University Professor (W2) of Physical Chemistry at the University of Rostock, Germany, leading the Corzilius group. His research focuses on solid-state NMR spectroscopy, dynamic nuclear polarization (DNP), and applications in biomolecules and materials. He holds affiliations with the Leibniz Institute for Catalysis (LIKAT) and serves on multiple academic boards, including the transregional Collaborative Research Center TRR 386 and the journal Magnetic Resonance . Education: 1999: Studies of Chemistry, TU Darmstadt 2005: Diploma in Physical Chemistry (TU Darmstadt) 2008: Ph.D. in Physical Chemistry (TU Darmstadt) Research Interests: Solid-state NMR, DNP for sensitivity enhancement, paramagnetic metal ions, biomolecular dynamics, and method development. His work bridges theoretical and experimental approaches to advance structural and functional studies of complex systems like proteins, nucleic acids, and catalytic materials. Recent Article Trends: Focus on DNP applications in biomolecular interfaces, novel polarizing agents (e.g., Gd(III) complexes), and methodological advancements like serial polarization transfer and electron-decoupled DNP. Contributions span inorganic chemistry, materials science, and biophysical systems. Awards: Emmy Noether Fellowship (2012) Felix Bloch Lecture (2016) Regitze M. Vold Memorial Prize (2017) Best Ph.D. Supervision (2018) Grants & Labs: Principal Investigator of the Emmy Noether Group (2013–2019), now leading the DNP research team at the University of Rostock. Collaborates closely with LIKAT on catalytic and materials projects. His group actively develops open-access publishing platforms like Magnetic Resonance and hosts international conferences. Labs/Teams: The Corzilius group at the Institute of Chemistry (Rostock) specializes in NMR method development and applications. Associated with LIKAT for interdisciplinary catalysis research.

Yaojun Zhangمشاهده پروفایل

استادیار

• Biological Physics
• Biophysics
• Theoretical Physics
• +۳ مورد دیگر

Yaojun Zhang is an Assistant Professor in the Department of Physics & Astronomy and the Department of Biophysics at Johns Hopkins University. She earned her PhD in Physics from the University of California, San Diego (2015), followed by postdoctoral fellowships at the Princeton Center for Theoretical Science (2015-2018) and the Princeton Center for the Physics of Biological Function (2018-2021). Her research focuses on biological physics, particularly the complex behaviors of biomolecules and their assemblies across scales—from single-molecule folding to intracellular transport and biomolecular phase separation. She employs theoretical, mathematical, and computational tools to bridge biological questions with physical principles. Education PhD in Physics, University of California, San Diego (2015) Postdoctoral Fellowships: Princeton University (2015-2021) Research Interests Her group studies biomolecular condensates and liquid-liquid phase separation, exploring how microscopic interactions determine macroscopic properties of cellular compartments. Key areas include: Biomolecular condensate formation and dynamics Phase separation in cellular environments Interactions between biomolecules and cellular components Biophysics of intracellular transport Collaborations & Tools Zhang collaborates with experimentalists to validate theoretical models and develops frameworks for understanding condensate functions, such as surface tension, stoichiometry, and phase diagrams. Her work addresses challenges like condensate stability, molecular exclusion, and biological function regulation. Labs & Resources She leads the Zhang Lab , which integrates experimental and computational approaches. Her team’s research is supported by resources at the Bloomberg Center for Physics and Astronomy.

• Drug Delivery
• Nanomedicine
• Biopharmaceutics
• +۷ مورد دیگر

Dr. Shyh-Dar Li is a Professor and Tong Louie Chair in Pharmaceutical Sciences at the University of British Columbia's Faculty of Pharmaceutical Sciences, where he also serves as Chair of Nanomedicine and Chemical Biology. With a BSc in pharmacy from National Taiwan University (1998) and PhD in pharmaceutical sciences from UNC Chapel Hill (2008), followed by postdoctoral training at UC San Diego's Moores Cancer Center (2009), Dr. Li has established himself as a leading researcher in advanced drug delivery systems. His research focuses on developing innovative nanomedicine platforms for targeted delivery of biological therapeutics including peptides, proteins, antibodies, and nucleic acids. Dr. Li's laboratory has pioneered several novel drug delivery approaches, particularly in lipid-based nanoparticles, phospholipid-free vesicles, and polymer systems for cancer immunotherapy, pain management, and protein delivery. His work bridges fundamental nanotechnology with translational applications for difficult-to-treat diseases. Analysis of his recent publications reveals a strong emphasis on tumor microenvironment modulation, endosomal escape mechanisms for nucleic acid delivery, and non-invasive delivery routes for protein therapeutics. His research demonstrates increasing sophistication in nanocarrier engineering, with recent work incorporating machine learning approaches to optimize nanoparticle design and expanding into immunomodulatory therapies that harness the body's immune system to fight cancer. Scientific Recognition: 2014 AFPC New Investigator Award 2013 AAPS New Investigator Award in Pharmaceutics and Pharmaceutical Technologies 2013 CIHR New Investigator Award 2013 CSPS Early Career Award 2012 Prostate Cancer Foundation Young Investigator Award Dr. Li's research program has been consistently supported by major Canadian funding agencies including CIHR, NSERC, and MITACS. He actively collaborates across disciplines and accepts graduate students into his research program, focusing on cutting-edge approaches to overcome biological barriers in drug delivery. His laboratory, the Laboratory of Targeted Drug Delivery and Nanomedicine, serves as a hub for innovation in pharmaceutical nanotechnology.

Shasha Chongمشاهده پروفایل

استادیار

• Transcriptional Regulation
• Intrinsically Disordered Proteins
• Single-Molecule Biophysics
• +۴ مورد دیگر

Shasha Chong is an Assistant Professor of Chemistry at the California Institute of Technology and a Ronald and JoAnne Willens Scholar. She earned her B.S. from the University of Science & Technology of China (2008) and Ph.D. from Harvard University (2014). Her research bridges chemistry, physics, and biology to investigate the molecular mechanisms of cellular processes, focusing on intrinsically disordered regions (IDRs) in transcription proteins. Research Focus: IDRs in transcriptional regulation, cancer biology, liquid-liquid phase separation, and single-molecule imaging techniques. Grants & Awards: CCE Innovation Award (2024), ALSF Innovation Grant, Mallinckrodt Research Grant, Margaret E. Early Medical Research Trust Grant. Collaborations: Caltech-City of Hope Biomedical Research Initiative Grant (2025). Teaching: Co-instructor for courses like Biochemistry Laboratory (Ch 11) and Advanced Topics in Biochemistry (BMB/Bi/Ch 174). Labs & Teams: Leads the Chong Laboratory at Caltech, focusing on interdisciplinary approaches combining single-molecule imaging, genome editing, and bioinformatics.

• Biosensors
• Functional Nucleic Acids
• Sol-Gel Materials
• +۳ مورد دیگر

John D Brennan is a Professor in the Department of Chemistry & Chemical Biology at McMaster University. He is affiliated with the Biointerfaces Institute and focuses on developing innovative biosensing technologies and functional nucleic acid-based assays. His research integrates materials science, biochemistry, and analytical chemistry to create practical diagnostic tools for healthcare applications. Key research areas include the design of DNA aptamers and DNAzymes for detecting biomarkers (e.g., eosinophil peroxidase, SARS-CoV-2 spike proteins), development of paper-based diagnostic platforms, and optimization of sol-gel materials for enzyme entrapment. His work emphasizes high-throughput screening, point-of-care testing, and CRISPR-based biosensing systems. Notable contributions include a rapid sputum-based assay for asthma biomarkers and a universal DNA aptamer for SARS-CoV-2 variants. His lab also explores functional nucleic acid circuits and their integration into scalable diagnostic devices. Brennan’s teaching includes advanced courses in analytical chemistry and biochemical assay development. His work has been featured in journals like *Angewandte Chemie*, *Analytical Chemistry*, and *ChemBioChem*, with a focus on translating fundamental research into practical clinical applications.

Virgil Percecمشاهده پروفایل

استاد

• Organic Chemistry
• Supramolecular Chemistry
• Nanotechnology
• +۴ مورد دیگر

Virgil Percec is the P. Roy Vagelos Professor of Chemistry at the University of Pennsylvania, affiliated with the School of Arts & Sciences and the Department of Chemistry. His research focuses on organic, supramolecular, and macromolecular chemistry, with an emphasis on self-assembly, drug delivery systems, and biomimetic nanosystems. He holds a B.S. and Ph.D. from institutions in Jassy, Romania, and conducted postdoctoral research at the University of Freiburg and the University of Akron. Research Interests: Percec’s work integrates synthetic methods, catalysis, and structural biology to design functional nanosystems. Key areas include hierarchical folding, supramolecular chirality, and synthetic mimics of biological membranes. His lab explores mRNA delivery systems using Janus dendrimers and studies self-organized structures like helical columns and quasicrystals. Recent Articles: His recent publications highlight advancements in mRNA delivery mechanisms, supramolecular architectures, and polymer synthesis innovations. The group’s work often involves interdisciplinary collaborations, bridging chemistry, materials science, and bioengineering. Awards: Percec was elected a Foreign Member of the Academia Europaea (2020) and delivered the inaugural ACS Kavli Lecture (2011). His lab has trained numerous students and postdocs, including Juncheng Lu (Master’s Capstone Award recipient) and Devendra Maurya (SET-LRP research). Labs & Teams: The Percec Research Laboratory at Penn develops cutting-edge biomaterials and supramolecular systems. The group collaborates globally, with projects funded by grants exploring nanotechnology and drug delivery.

Ron Drorمشاهده پروفایل

استاد

• Computational Biology
• Machine Learning
• Molecular Dynamics Simulation
• +۶ مورد دیگر

Ron Dror is the Cheriton Family Professor of Computer Science at the Stanford Artificial Intelligence Lab , with courtesy appointments in Structural Biology and Molecular & Cellular Physiology . He also holds affiliations with Bio-X, the Institute for Human-Centered Artificial Intelligence (HAI), the Institute for Computational and Mathematical Engineering (ICME), Sarafan ChEM-H, and the Wu Tsai Neurosciences Institute. Education: PhD in Electrical Engineering and Computer Science, MIT MPhil in Biological Sciences, University of Cambridge (Churchill Scholar) BS in Mathematics and Electrical & Computer Engineering, Rice University (summa cum laude) Ron leads a multidisciplinary research group that combines molecular simulation and machine learning to study biomolecular structure, dynamics, and function. His work focuses on developing computational methods to accelerate drug discovery by predicting molecular interactions and designing more effective therapeutics. Current projects include the PENSA software library for analyzing biomolecular ensembles and FRAME framework for structure-based ligand design. His research has produced groundbreaking work on G-protein-coupled receptors (GPCRs) , RNA structure prediction , and mitochondrial transport mechanisms . Key publications highlight applications of geometric deep learning and molecular dynamics simulations in structural biology. Scientific Awards: Cheriton Family Professorship (2023) Two Gordon Bell Prizes (2014, 2009) Best Paper Awards at NeurIPS (2021), IPDPS (2013), SC11 (2011), SC09 (2009), SC06 (2006) Science Magazine Top 10 Breakthrough (2010) Fulbright Scholarship , NSF Fellowship , DoD Fellowship , Whitaker Foundation Fellowship Ron has advised numerous doctoral and master’s students including EJ Fine , Masha Karelina , and Briana Sobecks . His lab collaborates with experimentalists across academia and industry, applying computational methods to diverse biomedical problems such as RNA structure prediction , GPCR signaling , and mitochondrial metabolism .

Dieter Braunمشاهده پروفایل

استاد

• Origins of Life
• Prebiotic Chemistry
• Molecular Evolution
• +۵ مورد دیگر

Dieter Braun is a Professor in the Faculty of Physics at Ludwig Maximilian University of Munich (LMU), leading the Functional NanoSystems research group. He serves as speaker of the CRC 235 Emergence of Life and coordinates the Molecular Origins component of the Origins Cluster. Dr. Braun holds an ERC Synergy Grant (starting April 2025), leads the CRC 392 Molecular Evolution (starting April 2024), and is a Fellow in the Max Planck School Matter to Life (since October 2023). His research focuses on understanding the physical mechanisms that could have led to the emergence of Darwinian evolution from prebiotic molecules on early Earth. Braun's laboratory investigates non-equilibrium settings, particularly asymmetrically heated open cracks in rocks, which create intricate wet-dry cycles, temperature gradients, and fluidic effects that could drive molecular evolution. His work bridges physics, chemistry, and biology to explore how dead molecules might combine through physical forces into autonomous mechanisms of evolution. Analysis of Braun's recent publications reveals a strong focus on thermal gradients and non-equilibrium physics in prebiotic environments. His research demonstrates how heat flows can concentrate molecules, drive polymerization, create pH gradients, and enable non-enzymatic replication of nucleic acids. The publications span high-impact journals including Nature, Nature Physics, and Nature Chemistry, showing interdisciplinary work connecting physics, chemistry, geology, and biology in the context of life's origins. Klung-Wilhelmy Weberbank Price (2011) Technology Transfer Price of the DPG (with LMU and NanoTemper) Deutscher Innovationspreis (2012) Step Award (2012) Dr. Braun has successfully mentored numerous PhD students, including Stefan Duhr and Philipp Baaske who founded the award-winning startup NanoTemper Technologies. His research is supported by multiple prestigious grants including ERC Starting, Advanced, and Synergy Grants, as well as funding from the Simons Collaboration on the Origins of Life. His laboratory collaborates extensively with other researchers across disciplines and institutions, particularly with Hannes Mutschler in the new ERC Synergy project. The Braun laboratory operates within the CRC 235 Emergence of Life and the Origins Cluster at LMU Munich, with strong connections to the Max Planck Society through the Max Planck School Matter to Life. The research group maintains active collaborations with geochemists, biophysicists, and molecular biologists to create comprehensive experimental models of prebiotic environments.

Celeste Saguiمشاهده پروفایل

استاد

• Computational Biophysics
• Biomolecular Simulations
• Free Energy Methods
• +۵ مورد دیگر

Celeste Sagui is a Professor in the Department of Physics at North Carolina State University (NC State), affiliated with the College of Sciences. She holds additional roles as a faculty affiliate in Genomics Sciences at NC State and is a member of the Center for High Performance Simulation. Her research focuses on computational biophysics, biomolecular simulations, and free energy methods applied to nucleic acid structures, protein dynamics, and nanotechnology systems. She has contributed to the AMBER simulation package development, co-authoring versions from 10 to 14. Education: Doctorate in Physics, University of Toronto (1995) Licentiate degree, National University of San Luis, Argentina Research Interests: Sagui’s work explores DNA/RNA structure and phase transitions, electrostatic interactions, and methodologies for large-scale molecular simulations. Recent studies include nucleic acid hairpin instabilities linked to neurodegenerative diseases, polyglutamine aggregation mechanisms, and novel DNA motifs like the eGZ structure in Z-DNA. She employs quantum chemistry, density functional theory, and phase-field models to investigate systems ranging from biomolecules to nanomaterials. Publications: Her recent work emphasizes nucleic acid dynamics, free energy landscapes, and computational methods for studying diseases such as Friedreich’s ataxia and polyglutamine disorders. Key contributions include advancements in laser-driven simulations and infrared spectroscopy analysis of protein structures. Labs/Teams: Active in the Center for High Performance Simulation, focusing on high-throughput computational modeling and collaborative software development for biomolecular research.

Donald Rioمشاهده پروفایل

استاد

• Nucleic Acid Transactions
• Transposable Elements
• RNA Binding Proteins
• +۳ مورد دیگر

Donald Rio holds the Richard and Rhoda Goldman Distinguished Chair in the Biological Sciences and is a Professor of Biochemistry, Biophysics, and Structural Biology. He is affiliated with the Division of Biochemistry and Molecular Biology and the Center for Integrative Genetics. His lab focuses on nucleic acid transactions, including transposable element mobilization (P elements) and RNA binding protein mechanisms controlling alternative splicing. Research highlights include studies on THAP9 proteins in humans/zebrafish, cryo-EM structural analysis of transposase-DNA complexes, and splicing regulation in neurodegenerative diseases like ALS and Parkinson’s. His work combines biochemical, genetic, and computational approaches, including the development of the Junction Usage Model (JUM) for splicing analysis. Research interests span transposition mechanisms linked to HIV integration, immune system recombination, and evolutionary genome dynamics. His team investigates how RNA binding proteins like hnRNPA1 influence splicing in disease contexts, with projects involving CRISPR-based models and patient RNA-seq data analysis. Collaborations include studies on splicing accuracy across tissues and age, and the impact of splicing defects in neurodegenerative disorders. Key awards include the Goldman Chair. His lab’s contributions bridge fundamental molecular mechanisms with translational applications in genetic disease modeling and drug discovery. Recent work focuses on isogenic stem cell models (iSCORE-PD) for Parkinson’s research and structural biology insights into transposase function. Grants and projects involve NIH funding for ALS splicing studies and collaborations with institutions like the Buck Institute. His lab actively publishes in top journals such as Genome Research , PNAS , and Nature , with a strong emphasis on cryo-EM and bioinformatic methods.

Elisabeth Princeمشاهده پروفایل

استادیار

• Polymer Chemistry
• Biomedical Engineering
• Materials Science
• +۷ مورد دیگر

Elisabeth Prince is an Assistant Professor at the University of Waterloo, specializing in polymer chemistry and biomaterials. Her research focuses on developing advanced materials for biomedical applications, sustainable materials, and microfluidic technologies. Key areas include conductive hydrogels, cleavable polymers for recyclability, and biomimetic systems for drug delivery and cancer therapy. Her work bridges disciplines such as materials science, nanotechnology, and biomedical engineering. Recent studies involve applications in strain-stiffening hydrogels, filamentous aerogels for electromagnetic shielding, and microfluidic platforms for organoid production. These innovations aim to address challenges in regenerative medicine, environmental sustainability, and personalized cancer treatments. No scientific awards are listed in the provided materials. Research activities include collaborations on 3D-printed microfluidic devices and nanofibrillar hydrogels mimicking biological systems. No advising relationships or grants are explicitly mentioned in the text.

Jerelle A. Josephمشاهده پروفایل

استادیار

• Biomolecular Condensates
• Phase Separation
• Computational Biology
• +۴ مورد دیگر

Jerelle A. Joseph is an Assistant Professor at Princeton University , affiliated with the Department of Chemical and Biological Engineering and the Omenn-Darling Bioengineering Institute . They also hold associated faculty roles in the Department of Chemistry , Andlinger Center for Energy and the Environment , Princeton Institute for Computational Science and Engineering , and the Biophysics Graduate Program . Research Interests : The Joseph Group investigates the physicochemical principles governing biomolecular condensate formation, dissolution, and misregulation . Their work focuses on phase separation mechanisms , computational modeling of protein-RNA interactions , and engineering condensates for biomedical and sustainability applications , including therapeutic targeting of neurodegenerative diseases and design of synthetic microreactors . Scientific Awards : NIGMS MIRA (R35) Award (2024) Biophysical Society Award Lecture (2024) Chan Zuckerberg Initiative Investigator (2023) Postdoctoral Award, Biophysical Society IDP Subgroup (2022) Rising Star in Soft and Biological Matter (University of Chicago, 2020) Advising : Dr. Joseph advises graduate students including Ananya Chakravarti , Dominic Curtis , and Pablo Garcia . The group develops chemically-specific coarse-grained models using molecular dynamics , Monte Carlo sampling , and machine learning to study condensate microstructure , aging dynamics , and surface electrostatics .

Steven A. Corcelliمشاهده پروفایل

استاد

• Theoretical Chemistry
• Computational Molecular Science
• Biomolecular Binding
• +۵ مورد دیگر

Steven A. Corcelli is a Professor and Interim Dean of the College of Science at the University of Notre Dame, with a research focus on Theoretical Chemistry and Molecular Dynamics Simulations . His work bridges Physical Chemistry and Biochemistry , targeting Energy Applications and Biomolecular Binding Mechanisms . He leads the Computational Molecular Science & Engineering Laboratory (CoMSEL). Ph.D., Chemistry, Yale University (2001) Sc.B., Chemistry, Brown University (1997) Research interests span ionic liquids for Carbon Capture , aqueous electrolytes in battery technologies , and molecular binding processes in immunology and DNA interactions . His group employs GPU-accelerated simulations and weighted ensemble methods to uncover structural and dynamic motifs. Recent publications highlight trends in vibrational spectroscopy , TCR-MHC binding , and CO2 solvation mechanisms . Awards include the Thomas P. Madden Award (2020) , ACS Fellowship (2016) , and NSF CAREER Award (2009) . Staff: Erin Brossard (Ph.D.), Nell Karpinski, Shuang Wu, Noah Vasconez, Kaitlyn Handy, Isabel Thompson