جست‌وجوی استاد و پژوهشگر

Qiaowei Panمشاهده پروفایل

پژوهشگر

• Evolutionary Biology
• Molecular Biology
• Genetics
• +۷ مورد دیگر

Qiaowei Pan is a Researcher at the University of Lausanne , focusing on Evolution and Ecology . They have held a Guest Researcher role at the Institute of Molecular Biology gGmbH (IMB) in Mainz, Germany since 2023, and a Postdoctoral Researcher position at the University of Lausanne since 2018. Education: PhD in Molecular and Evolutionary Biology (2014-2018), INRAe, University of Rennes II, France Erasmus Mundus Master in Evolutionary Biology (MEME) (2012-2014), University of Groningen (Netherlands) & University of Montpellier II (France) BSc in Biology (2008-2012), University of North Carolina-Chapel Hill, USA Research Interests: Qiaowei Pan's work centers on the intersection of molecular genetics , evolutionary biology , and developmental biology , particularly in sex determination mechanisms across diverse animal models. Their studies span non-coding RNA regulation , sex chromosome evolution , and signal transduction pathways like TGF-β in reproductive systems. Publication Trends: Recent articles highlight expertise in sex determination systems (5/12 publications), genomic approaches (6/12), and fish developmental evolution . Collaborative work includes computational methods ( RADSex workflow ) and comparative studies across ant , goldfish , catfish , and cavefish models. Labs & Teams: Currently affiliated with the Keller-Valsecchi group at IMB and the Department of Evolution and Ecology at the University of Lausanne.

Knut Reinertمشاهده پروفایل

استاد

• Algorithmic Bioinformatics
• Genomic Sequence Analysis
• Proteomics
• +۷ مورد دیگر

Professor Knut Reinert is a leading figure in algorithmic bioinformatics at the Free University of Berlin, where he holds a professorship in the Department of Mathematics and Computer Science. He also maintains a significant affiliation with the Max Planck Institute for Molecular Genetics in Berlin, where he leads the Efficient Algorithms for Omics Data group. His research spans both institutions through the Reinert Lab, which focuses on developing novel computational approaches for biological data analysis. Reinert's educational background includes a Diploma in Computer Science (1994) and a Doctorate (Dr. Ing./Ph.D., 1999, with honors) from the Max-Planck-Institut for Computer Science and Universität des Saarlandes in Saarbrücken. Prior to his professorship, he worked as a computer scientist under Prof. Gene Myers at Celera Genomics in Rockville, USA (1999-2002). His primary research interests center on algorithmic bioinformatics with specific focus on developing novel algorithms and data structures for biomedical mass data analysis. This includes creating mathematical models for genomic sequence analysis and algorithms for mass spectrometry data to detect differential protein expression between normal and diseased samples. His work bridges the gap between computational tool development and practical biological applications, with particular emphasis on NGS and proteomics data. The publications and projects led by Prof. Reinert demonstrate a consistent focus on advancing computational methods in bioinformatics. His research spans genomic sequence analysis, RNA research (particularly long non-coding RNAs), parallel computing applications, and GPU acceleration for biological data processing. The work shows increasing sophistication in handling large-scale biological datasets through innovative algorithmic approaches. Intel® Parallel Computing Center designation for his lab CUDA Research Center status DFG funding of 530 thousand Euros for RNA research de.NBI funding of 2 million Euros BMBF funded projects 'LIVE-DREAM' and 'EssBar' Prof. Reinert leads multiple significant research projects and has established strong collaborations with international partners including Texas A&M, Kings College London, Eberhardt-Karls Universität Tübingen, Robert-Koch-Institute, and various Turkish institutions. His lab receives funding from major organizations including DFG, BMBF, and Intel. The Reinert Lab maintains active teaching responsibilities at FU Berlin, offering courses at BSc, MSc, and PhD levels using both traditional and innovative learning concepts like e-learning and inverted classrooms. The Reinert Lab consists of two interconnected research groups that work closely with experimental biologists and medical researchers to develop practical computational solutions for real-world biological problems. The lab has established itself as a key player in the German and international bioinformatics community through its development of the widely-used SeqAn library and participation in national infrastructure initiatives.

• Neural circuit mechanisms
• Adaptive learning
• State-dependent decision-making
• +۴ مورد دیگر

Dr. Sabine Krabbe is a Group Leader at the German Center for Neurodegenerative Diseases (DZNE) in Bonn, Germany, where she leads research on neural circuit mechanisms underlying adaptive learning and state-dependent decision-making. Her work integrates neuroscience, molecular biology, and behavioral approaches to understand how internal states influence behavior and how these processes are disrupted in neurological disorders. Dr. Krabbe's research focuses on the interactions between midbrain circuits of the substantia nigra and ventral tegmental area with their output structures such as the striatum and amygdala. She investigates how these networks integrate internal states with environmental cues to produce appropriate behavioral responses. Her laboratory employs state-of-the-art techniques including deep-brain calcium imaging at single-cell resolution in mice, opto- and pharmacogenetic manipulations, anatomical tracings, and molecular approaches to characterize neural circuit elements in detail. Her recent publications reveal significant insights into amygdala interneuron plasticity during fear learning, brain-wide representational drift in memory consolidation, and the molecular mechanisms underlying Parkinson's disease progression. Her work demonstrates how activity patterns within specific neural circuits change in early stages of neurodegenerative diseases and how this dysfunction contributes to cognitive deficits and emotional disturbances. Dr. Krabbe is actively involved in the neuroscience community, organizing the BonnBrain Conference 2026 and sharing research through social media platforms. She has established herself as an emerging leader in the field of systems neuroscience with a particular focus on the neural basis of emotional states and decision-making processes.

Dieter Braunمشاهده پروفایل

استاد

• Origins of Life
• Prebiotic Chemistry
• Molecular Evolution
• +۵ مورد دیگر

Dieter Braun is a Professor in the Faculty of Physics at Ludwig Maximilian University of Munich (LMU), leading the Functional NanoSystems research group. He serves as speaker of the CRC 235 Emergence of Life and coordinates the Molecular Origins component of the Origins Cluster. Dr. Braun holds an ERC Synergy Grant (starting April 2025), leads the CRC 392 Molecular Evolution (starting April 2024), and is a Fellow in the Max Planck School Matter to Life (since October 2023). His research focuses on understanding the physical mechanisms that could have led to the emergence of Darwinian evolution from prebiotic molecules on early Earth. Braun's laboratory investigates non-equilibrium settings, particularly asymmetrically heated open cracks in rocks, which create intricate wet-dry cycles, temperature gradients, and fluidic effects that could drive molecular evolution. His work bridges physics, chemistry, and biology to explore how dead molecules might combine through physical forces into autonomous mechanisms of evolution. Analysis of Braun's recent publications reveals a strong focus on thermal gradients and non-equilibrium physics in prebiotic environments. His research demonstrates how heat flows can concentrate molecules, drive polymerization, create pH gradients, and enable non-enzymatic replication of nucleic acids. The publications span high-impact journals including Nature, Nature Physics, and Nature Chemistry, showing interdisciplinary work connecting physics, chemistry, geology, and biology in the context of life's origins. Klung-Wilhelmy Weberbank Price (2011) Technology Transfer Price of the DPG (with LMU and NanoTemper) Deutscher Innovationspreis (2012) Step Award (2012) Dr. Braun has successfully mentored numerous PhD students, including Stefan Duhr and Philipp Baaske who founded the award-winning startup NanoTemper Technologies. His research is supported by multiple prestigious grants including ERC Starting, Advanced, and Synergy Grants, as well as funding from the Simons Collaboration on the Origins of Life. His laboratory collaborates extensively with other researchers across disciplines and institutions, particularly with Hannes Mutschler in the new ERC Synergy project. The Braun laboratory operates within the CRC 235 Emergence of Life and the Origins Cluster at LMU Munich, with strong connections to the Max Planck Society through the Max Planck School Matter to Life. The research group maintains active collaborations with geochemists, biophysicists, and molecular biologists to create comprehensive experimental models of prebiotic environments.

Susanne Foitzikمشاهده پروفایل

استاد

• Evolutionary Biology
• Behavioral Ecology
• Host-Parasite Coevolution
• +۱۳ مورد دیگر

Prof. Dr. Susanne Foitzik is a Professor of Evolutionary Biology at Johannes Gutenberg University Mainz since 2010, where she leads the Evolution & Behavioral Ecology of Ants research group at the Institute of Organismic and Molecular Evolution (IOME). Previously, she was Professor in Behavioral Ecology at LMU Munich (2004-2010) and Assistant Professor in Zoology at the University of Regensburg (2000-2004). She earned her PhD in Biology from Julius Maximilian University, Würzburg in 1998. Her research integrates approaches from behavioral ecology through genomics to epigenetics, focusing on ants as model organisms to study complex social behaviors. Host-parasite coevolution and social parasitism in ants Molecular mechanisms underlying division of labor Reversal of the fecundity-longevity trade-off in social insects Gene regulation in phenotypic plasticity Evolution of chemical communication systems Analysis of her recent publications (2022-2025) reveals a strong focus on molecular mechanisms of social behavior, with particular emphasis on host-parasite interactions, epigenetic regulation of behavior, and genomic adaptations in social insects. Her work increasingly combines transcriptomic, proteomic, and functional genomic approaches to understand the molecular basis of social evolution. Among her notable scientific achievements: Speaker of Research Training Group 2626 GenEvo: Gene Regulation in Evolution (2019-present) Speaker of EES Master Program funded by VW foundation (2007-2010) DAAD Fellow at State University of New York (1992-93) Prof. Foitzik has supervised numerous PhD students and postdocs, including Maide Macit, Tom Sistermans, and Marcel Caminer. Her research is supported by multiple DFG-funded projects investigating host-parasite coevolution, the role of gene regulation in division of labor, and parasite interference in host gene expression. She serves as Handling Editor for Biology Letters and previously served on the editorial board of Insectes Sociaux. Her research group operates within the Institute of Organismic and Molecular Evolution (IOME) at Mainz, with laboratory facilities at the Biozentrum I. The group collaborates extensively with researchers across Germany and internationally, including partnerships with institutions in Frankfurt, Freiburg, Bristol, and Tel Aviv.

Philipp Neumannمشاهده پروفایل

استاد

• High-Performance Computing
• Scientific Computing
• Parallel and Distributed Systems
• +۴ مورد دیگر

Philipp Neumann is a Professor and Chair of High-Performance Computing at Helmut Schmidt University since 2019. Previously, he held roles including Senior Researcher at the German Climate Computing Center (2016–2019), Postdoc at the University of Hamburg (2017–2019), and completed his Habilitation in Scientific Computing at TU Munich (2019). He transitioned to DESY/Universität Hamburg in May 2024. Education : PhD (Dr. rer. nat.) in Scientific Computing at TU Munich (2008–2013) Habilitation in Scientific Computing at TU Munich (2019) Studies in Technomathematics at Friedrich-Alexander University Erlangen-Nuremberg (2003–2008) Research Interests focus on high-performance computing, parallel and distributed systems, computational science, and applications in climate modeling. His work bridges computational methods with medical challenges, including surgical simulation training, wound healing mechanisms, and gastrointestinal pathology. Professional Activities include leadership roles in major conferences such as steering committee member for ISPDC (since 2021) and program committee roles in IPDPS, ICCS, and IEEE Cluster. He also managed the DFG priority program SPPEXA (2013–2016). Labs/Teams include the Chair for High-Performance Computing at Helmut Schmidt University and collaborations with the German Climate Computing Center. His current work at DESY/Universität Hamburg likely expands these computational efforts into interdisciplinary research.

Franz Lennard Ricklefsمشاهده پروفایل

استاد

• Neurosurgery
• Neuro-oncology
• Molecular Neurobiology
• +۵ مورد دیگر

Prof. Dr. med. Franz Lennard Ricklefs is a Senior Physician and Head of the Working Group at the Department of Neurosurgery, University of Hamburg Faculty of Medicine. He is a Medical Specialist in Neurosurgery with cross-disciplinary expertise in neuro-oncology, molecular pathology, and extracellular vesicle research. Affiliations: University Medical Center Hamburg-Eppendorf (UKE), European Liquid Biopsy Society (ELBS), International Consortium on Meningiomas (ICOM) Research Interests: His work focuses on neurosurgical oncology, particularly glioblastoma and meningioma pathobiology. He investigates DNA methylation patterns, extracellular vesicle biomarkers, and liquid biopsy implementation in clinical neuro-oncology. Additional interests include surgical outcomes for epilepsy and aneurysm management. Article Trends: Over the last decade, Dr. Ricklefs has published extensively on: Extracellular vesicle applications as liquid biopsy markers DNA methylation subclasses for glioblastoma and meningioma Multicenter surgical outcome benchmarking Immune evasion mechanisms in neuro-oncology Technological innovations in neurosurgical visualization Molecular characterization of rare CNS tumors Professional Contributions: He co-authored the MISEV2023 guidelines for extracellular vesicle studies and participates in international consensus reviews for meningioma classification. His collaborations span institutions across Europe and North America.

Andrew Bassettمشاهده پروفایل

پژوهشگر

• Genome Engineering
• Neurodegenerative Diseases
• Stem Cell Research
• +۵ مورد دیگر

Dr. Andrew Bassett serves as Head of the Cellular and Gene Editing Research group at the Wellcome Sanger Institute, where he develops cutting-edge genome engineering techniques using human pluripotent stem cells to investigate neurodegenerative diseases including Alzheimer's and Parkinson's. His work focuses on scaling genetic screening approaches and improving CRISPR specificity for modeling complex disease mechanisms. His academic training includes: PhD at the MRC Laboratory of Molecular Biology (MRC-LMB) with Andrew Travers on chromatin remodelling in heterochromatin formation Postdoctoral research with David Baulcombe at the University of Cambridge studying small RNA roles in chromatin modification Additional postdoctoral work with Chris Ponting at the MRC Functional Genomics Unit (MRC-FGU) in Oxford, where he pioneered CRISPR applications in Drosophila Bassett's research program centers on developing advanced genome engineering methodologies for precise modulation of gene expression networks during development and neurodegeneration. His group specializes in creating complex editing events (SNPs, paired knockouts, enhancer perturbations) within iPSC-derived models, with particular emphasis on epigenetic regulation and transcriptional control. Current projects integrate single-cell 'omics and phenotypic assays to decode genetic causes of neurodegenerative disorders through the OpenTargets consortium. Analysis of his 15 most recent publications reveals dominant trends in CRISPR technology development (35%), neurodegenerative disease modeling (30%), and single-cell functional genomics (25%). His work consistently bridges methodological innovation with disease mechanism studies, increasingly incorporating multi-omics approaches and expanding into cancer immunology and infectious disease applications since 2022. As group leader, Bassett mentors postdoctoral researchers and PhD students while securing major funding for genome engineering initiatives. His team operates within the Sanger Institute's Cellular Operations division and maintains critical partnerships with the OpenTargets consortium for therapeutic target validation. The laboratory specializes in high-throughput screening platforms using iPSC-derived neural and microglial models, with recent methodological advances including scSNV-seq and ONE-STEP tagging systems that significantly enhance precision genome editing capabilities.

Michael Boutrosمشاهده پروفایل

استاد

• Functional Genomics
• Structural Genomics
• Wnt Signaling
• +۷ مورد دیگر

Michael Boutros is a Full Professor at Heidelberg University and Head of Division at the German Cancer Research Center (DKFZ). He currently serves as Dean of the Medical Faculty at Heidelberg University (since 2023) and Director of the Marsilius Kolleg (since 2020). He has held leadership roles including Coordinator of the Functional and Structural Genomics Program at DKFZ (2014–2023) and Acting Scientific Director (2015–2016). His academic base is within the Medical Faculty, focusing on molecular oncology and functional genomics. PhD, Witten/Herdecke University (1993–1996) Postdoctoral Research, Harvard Medical School (1999–2003) MPA, John F. Kennedy School of Government, Harvard University (1999–2001) Additional training: Cold Spring Harbor Laboratory, SUNY Stony Brook His research centers on Wnt signaling, functional genomics, and cancer pathways. He leads major research initiatives such as CRC 1324 on Wnt signaling and the ERC Synergy Grant DECODE. His work integrates high-throughput screening, CRISPR, and systems biology to dissect signaling networks in cancer and development. He has pioneered genome-wide RNAi and CRISPR screens to identify novel regulators of Wnt signaling across models. The 15 most recent articles reflect a strong focus on Wnt pathway regulation using functional genomics in both Drosophila and mammalian systems. Themes include high-throughput screening, CRISPR-based validation, cross-species conservation, and therapeutic targeting. Keywords span Cancer Biology, Systems Biology, and Signal Transduction, with subfields like RNAi, ubiquitination, stem cell regulation, and machine learning in image analysis. Michael Boutros has received numerous scientific honors: Elected member, Leopoldina National Academy of Sciences (2022) Elected member, Heidelberg Academy of Sciences (2022) EMBO Member (2013) ERC Advanced Grant (2012) Johann-Georg Zimmermann Research Award (2007) EMBO Young Investigator (2005) Member, 'Die Junge Akademie' (2003) He has been a recipient of the Emmy-Noether Program, McCloy Fellowship, Boehringer Ingelheim PhD Fellowship, Studienstiftung Fellowship, and Fulbright Fellowship. As a mentor and research leader, he has supervised numerous early-career scientists and coordinated large collaborative grants including the FP7 'CancerPathways' project. He currently serves as Speaker of the Research and Strategy Commission at Heidelberg University and Managing Director of the Health and Life Science Alliance Heidelberg Mannheim. He leads the CRC 1324 on Wnt signaling and is Coordinating PI of the ERC Synergy Grant DECODE. He is also Spokesperson of DFG Research Group 1036 and Coordinator of the former FP7 Coordinated Project 'CancerPathways'. His lab employs cutting-edge functional genomics tools to decode signaling networks in cancer and development.

Nikolaus Rajewskyمشاهده پروفایل

استاد

• RNA Biology
• Gene Regulation
• Single-Cell Transcriptomics
• +۶ مورد دیگر

Nikolaus Rajewsky is a leading Professor at the Max Delbrück Center for Molecular Medicine (MDC) and Charité – Universitätsmedizin Berlin , where he founded and directs the Berlin Institute for Medical Systems Biology (BIMSB) . His lab integrates experimental (biochemistry, molecular biology) and computational (bioinformatics, physics) approaches to study RNA regulation in gene expression , with applications to developmental biology, regeneration, neurodegenerative diseases, and cancer . Using model systems like C. elegans , planaria, and human brain organoids, his team pioneers cutting-edge methods such as MirDeep , DistMap , and FLAM-seq for RNA analysis. His research focuses on single-cell transcriptomics , spatial RNA sequencing , and circular RNA (circRNA) regulation , revealing novel roles for circRNAs like CDR1as in neuropsychiatric disorders. Recent work includes 3D tumor microenvironment mapping and computational modeling of RNA metabolism in diseases. Scientific Awards : Gottfried Wilhelm Leibniz Prize (2012) EMBO Membership (2010) Honorary PhD, Sapienza University of Rome (2014) Berlin Science Award (2009) His team's recent articles highlight breakthroughs in 3D spatial transcriptomics , circRNA degradation mechanisms , and mitochondrial disease modeling using human brain organoids. The lab actively collaborates with clinical partners across Charité and European institutions, driving the LifeTime initiative for cell-based interceptive medicine.

Jörg Hackermüllerمشاهده پروفایل

استاد

• Bioinformatics
• Omics Data Analysis
• Toxicology
• +۳ مورد دیگر

Prof. Dr. Jörg Hackermüller is a computational biologist with expertise in Omics data integration Toxicology Environmental risk assessment Non-coding RNA biology . He serves as Head of the Department of Computational Biology and Chemistry at the Helmholtz Centre for Environmental Research (UFZ) since 2024 and holds a Professorship at the Faculty of Mathematics and Computer Science at Leipzig University since 2021. His research focuses on Developing AI methods for chemical toxicity prediction Multi-omics integration for mechanistic toxicology Data standardization in environmental monitoring Non-coding RNAs as biomarkers in disease and toxicity and has produced 15+ recent publications spanning tools like multiGSEA and deepFPlearn+ . He collaborates with teams across UFZ Leipzig University Novartis Fraunhofer Institute and leads projects like InCeTo and SafePol , integrating exposome research with systems biology.

Lars Maegdefesselمشاهده پروفایل

استاد

• Vascular Biology
• Cardiovascular Disease
• Atherosclerosis
• +۳ مورد دیگر

Prof. Lars Mägdefessel is a Professor of Vascular Biology at the Technical University of Munich (TUM), leading the Molecular Vascular Biology group within the TUM School of Medicine and Health. His research focuses on non-coding RNAs in vascular diseases, particularly atherosclerosis and aortic aneurysms, using translational approaches for molecular treatment discovery. He holds an MD from Johannes Gutenberg University (Mainz, Germany), completed cardiology clinical training, and postdoctoral research at Stanford University before joining TUM in 2016. Education: MD from Johannes Gutenberg University, Mainz Postdoctoral training at Stanford University, USA Assistant Professor at Karolinska Institute, Sweden Research Interests: Non-coding RNA regulation in vascular pathology Mechanisms of atherosclerotic plaque vulnerability Translational therapies for vascular diseases Advanced aortic aneurysm progression Awards include the ERC Consolidator Grant (2023), Russell Ross Award (2023), and Heisenberg Professorship (2016). His lab is supported by the German Center for Cardiovascular Research (DZHK).

G. Petur Nielsenمشاهده پروفایل

استاد

• Bone and Soft Tissue Pathology
• Molecular Genetics of Bone Tumors
• Chordoma Research
• +۵ مورد دیگر

G. Petur Nielsen, MD is a Professor of Pathology at Harvard Medical School and serves as Subspecialty Head, Bone and Soft Tissue Pathology at Massachusetts General Hospital . With a clinical focus on bone and soft tissue tumors, his expertise spans diagnostic pathology, molecular genetics of neoplasms, and ancillary testing applications. Research interests center on Pathology and biology of bone/soft tissue tumors Molecular genetics of bone and soft tissue neoplasms Chordoma and sarcoma research Epithelioid vascular tumor differentiation Mesenchymal tumors of the female genital tract His work includes landmark studies on tumor misdiagnosis rates, immunohistochemical profiling, and genomic analysis of chordomas. Scientific contributions appear in leading journals like Nature and American Journal of Surgical Pathology , with major emphasis on Molecular tumor classification Mutational signature analysis Translational oncology Diagnostic accuracy improvement Genomic instability mechanisms

Ghazaleh Tabatabaiمشاهده پروفایل

استاد

• Neuro-Oncology
• Glioma Biology
• Meningioma Research
• +۵ مورد دیگر

Professor Ghazaleh Tabatabai serves as Head of Department for Clinical and Experimental Neuro-Oncology at the Hertie Institute for Clinical Brain Research, University of Tübingen. She leads a multidisciplinary research group focused on translational neuro-oncology with active collaborations through the German Glioma Network, German Cancer Consortium (DKTK), European Organisation for Research and Treatment of Cancer (EORTC), European Association of Neuro-Oncology (EANO), and International Consortium on Meningioma (ICOM). Her research program centers on molecular mechanisms of tumorigenesis, therapy resistance, and treatment-induced vulnerabilities in nervous system tumors. The laboratory employs CRISPR screening technologies, molecular profiling, and preclinical models to identify therapeutic targets, with particular expertise in glioma and meningioma biology. Current projects span from discovery through validation to clinical application, including phase I/II trials of novel therapies such as CureVac's mRNA vaccine candidate CVGBM. Recent publications demonstrate leadership in molecular classification of meningiomas, CRISPR-based target discovery, immunotherapy development, and clinical trial design. Her work on the TRACE app for patient-reported outcomes and the PRIDE trial for dose-escalated radiation therapy represents significant clinical translation efforts. The 2024-2025 publication record shows strong productivity with high-impact papers in Neuro-Oncology, Nature Medicine, and Genome Biology. Elected spokesperson of the DFG Board for Neuroscience (2024) Active participation in EANO guideline development Leadership in multiple international consortia including ICOM Principal investigator for clinical trials including N2M2/NOA-20 umbrella trial Professor Tabatabai mentors a large research team including PhD students, medical doctoral candidates, and postdoctoral researchers. Her laboratory maintains active clinical collaborations across neurosurgery, radiation oncology, and medical oncology departments. She is featured in the 'Key To My Research' podcast discussing tumor intelligence and regularly presents at major neuro-oncology conferences including ASCO, EANO, and SNO.

Michael Sattlerمشاهده پروفایل

استاد

• Biomolecular NMR Spectroscopy
• Structural Biology
• RNA Regulation
• +۷ مورد دیگر

Prof. Dr. Michael Sattler is a Full Professor of Biomolecular NMR at the Technical University of Munich (TUM) and Director of the Institute of Structural Biology at Helmholtz Zentrum München. He leads the Molecular Targets & Therapeutics Center and directs the Bavarian NMR Center. His research focuses on integrative structural biology, elucidating molecular mechanisms of biological pathways through advanced NMR techniques combined with cryo-EM, SAXS, and crystallography. Key areas include RNA regulation (alternative splicing, non-coding RNAs), disease mechanisms (e.g., spinal muscular atrophy), and structure-based drug discovery for cancer and infectious diseases. Education & Career PhD in Chemistry (1995) from Goethe University Frankfurt Postdoc at Abbott Laboratories (Chicago) and EMBL Heidelberg (Group Leader, 1997–2007) Full Professor at TUM since 2007 Director roles at Helmholtz Munich and Bavarian NMR Center since 2007 Research Highlights Prof. Sattler's work has revealed structural insights into RNA:protein interactions (e.g., SF1-RNA, U2AF), SMN Tudor domain recognition, and drug discovery strategies targeting Hsp90 and viral proteases. His lab pioneered integrative structural biology approaches and established high-end NMR facilities like the 1.2 GHz spectrometer. Awards & Recognition ERC Synergy Grant (2023) Leopoldina Membership (2017) EMBO Membership (2012) Erwin Schrödinger Prize (2020) Teaching & Leadership He teaches advanced courses in NMR spectroscopy, biochemistry, and structural biology at TUM. Leads EU Horizon-funded training networks (AEGIS, RNAct) and organizes international conferences on NMR and drug discovery.