جستجوی استاد راهنمای دانشگاهی

Pilar Blancafort is an Associate Professor at The University of Western Australia (UWA), holding positions in the School of Human Sciences and UWA Medical School. She is affiliated with the UWA Centre for Medical Research and collaborates with the Harry Perkins Institute of Medical Research. Her research focuses on epigenetic manipulation in cancer models, particularly breast and ovarian cancers, leveraging CRISPR/Cas9 and genome engineering technologies to develop precision medicine tools. She has co-led projects such as the Lionheart FX Automated High-Content Microscope initiative and actively investigates therapeutic reprogramming of cellular signaling pathways to improve cancer treatment outcomes. Blancafort’s research expertise includes genome engineering, cancer epigenetics, and women’s cancers. She collaborates internationally and has contributed to over 70 publications, 14 datasets, and 43 grants. Her work aligns with UN Sustainable Development Goals, emphasizing global health and innovation in medical research. Key areas of exploration involve reactivating tumor suppressors, silencing oncogenic drivers, and enhancing immune responses through CRISPR-based systems. Her studies on the PI3K-AKT-mTOR pathway and novel oncogenes further underscore her commitment to advancing targeted therapies. Blancafort has supervised 11 students and leads multiple grants, including projects on metastatic breast cancer therapies and ovarian cancer reprogramming. Her lab at the UWA Centre for Medical Research explores translational strategies for epigenome editing in cancer, with a focus on clinical applicability. Recent work highlights lipid nanoparticle delivery systems for CRISPR/dCas9 and synthetic epigenetic approaches to reverse mesenchymal-epithelial transitions in breast cancer.

• Cancer Biology
• Epigenetics
• Genome Engineering
• +۷ مورد دیگر

Dr. Andrew J. Woo is a Research Fellow at The University of Western Australia Medical School and the UWA Centre for Medical Research, affiliated with the Harry Perkins Institute of Medical Research. His research focuses on transcriptional gene regulation in stem/progenitor cells of blood and epithelial cancer stem cells. Dr. Woo completed his Bachelor of Science with Honours and PhD in Biochemistry at The University of Western Australia in 2004. He then pursued postdoctoral training under Dr. Alan B. Cantor at Children's Hospital Boston/Dana-Farber Cancer Institute at Harvard Medical School. He returned to Perth in 2012 with a fellowship from the Royal Perth Hospital Medical Research Foundation. Dr. Woo's research interests include understanding transcriptional gene regulatory mechanisms in stem/progenitor cells of blood and epithelial cancer stem cells. With Dr. Peter Leedman at the Harry Perkins Institute of Medical Research, he investigates the role of small non-coding RNA processing complexes in epithelial cancer onset and metastasis. His laboratory employs various techniques including protein-protein interaction identification via proteomics, protein-DNA interaction mapping, transcriptomics, functional genomics, and transgenic mouse models. His recent publications demonstrate a strong focus on cancer research, particularly breast cancer and hepatocellular carcinoma, with significant contributions to understanding transcription factors, oncogenes, and signaling pathways. His work often involves collaboration with other researchers at the Harry Perkins Institute and beyond. Dr. Woo has received the NHMRC project grant near-miss merit award in 2016 and has secured multiple research grants from organizations including Cancer Council of Western Australia and the Medical Research Foundation WA. Dr. Woo has been actively involved in research funding, serving as Chief Investigator on multiple grants since 2012. He also holds an external position as Lecturer and Unit Coordinator at Edith Cowan University from July 2018 to July 2043. His research is conducted within the UWA Centre for Medical Research, which is affiliated with the Harry Perkins Institute of Medical Research, a leading medical research facility in Western Australia.

• Transcriptional gene regulation
• Stem cells and cancer
• Haematopoiesis and blood disorders
• +۵ مورد دیگر

Xiaonan ZHANG is an Associate Professor in the Faculty of Science and Technology at the University of Canberra, leading the Hepatitis B Virus (HBV) Group within the Centre for Research into Therapeutic Solutions. He holds a PhD from Fudan University (2012) and previously worked at the Shanghai Public Health Clinical Centre until 2021. His research focuses on HBV molecular pathogenesis, therapeutic vaccine development, and next-generation sequencing applications in viral infections. His work has advanced understanding of HBV’s clinical outcomes, including the discovery of Capsid-Antibody-Complexes (CACs) and their role in pathogenesis. Collaborations span institutions like the Peter Doherty Institute, University of Queensland, and international partners such as Fudan University and University of Duisburg-Essen. Key projects include: Development of therapeutic mRNA vaccines for chronic HBV Clinical evaluation of CAC assays in HBV/HIV co-infections Metagenomic sequencing for pathogen identification Research interests emphasize translational medicine, with contributions to H7N9 influenza and SARS-CoV-2 studies during the pandemic. His team pioneered real-world analyses of viral and host factors in COVID-19 outcomes. Current focus includes liver-resident immune cell dynamics and novel diagnostic assays for HBV nucleic acids. Publications highlight innovations in HBV cccDNA tracking, immune complex mechanisms, and exosome-mediated signaling. No scientific awards were explicitly listed in the provided texts. Xiaonan actively collaborates on grants and supervises PhD students, advancing interdisciplinary approaches to viral diseases.

• Virology
• Molecular Biology
• Translational Medicine
• +۴ مورد دیگر

Professor Marcel Dinger is a prominent academic and researcher currently serving as Professor and Head of School for Biotechnology and Biomolecular Sciences at UNSW Sydney. With over 20 years of experience in genomics, he has established himself as a leading figure in both academic and entrepreneurial spheres within the field. He has published 153 papers with over 24,000 citations and maintains an h-index of 61 on Google Scholar. His leadership extends beyond academia as he serves as President of the Australasian Genomics Technologies Association (AGTA) and holds director positions at Pryzm Health and the National Centre for Indigenous Genomics (NCIG). Professor Dinger's research laboratory focuses on establishing new links between phenotype and genotype, particularly examining rare and complex diseases in relation to underexplored regions of the genome including pseudogenes, repetitive elements, non-canonical DNA structures, and noncoding RNAs. His work harnesses population-scale genomic datasets and sophisticated data science methods to bring an objective perspective to understanding how the genome stores information and how it is transacted in biology. His research interests span genomics, non-coding RNA biology, clinical applications of genomic medicine, and the development of computational approaches for analyzing complex genomic data. Analysis of Professor Dinger's recent publications reveals a strong emphasis on non-coding RNA research, particularly long noncoding RNAs and their roles in disease mechanisms. His work spans cancer genomics, neurological disorders, and fundamental genomic mechanisms including DNA secondary structures like i-motifs and G-quadruplexes. His research combines experimental approaches with advanced bioinformatics to address fundamental questions in genomic medicine and has significant translational implications for disease diagnosis and treatment. Highly Cited Researcher in Cross-Field category (2019, 2020, 2021) Fellow of the Faculty of Science (Research), Royal Society of Pathologists of Australasia (2016) NHMRC Career Development Award (2010) Queensland Government Smart Futures Fellowship (2009) Foundation of Research, Science and Technology New Zealand Postdoctoral Fellowship (2005) Professor Dinger has been instrumental in establishing and leading several significant research initiatives including Genome.One, one of the first companies globally to provide clinical whole genome sequencing services, and the Kinghorn Centre for Clinical Genomics at the Garvan Institute of Medical Research. His entrepreneurial experience includes founding four biotechnology and IT startups. He serves on multiple governance boards including the National Centre for Indigenous Genomics, focusing on using genomics to improve health outcomes for Australia's First Peoples. His laboratory at UNSW continues to advance our understanding of genomic regulation and its implications for human health and disease.

• Genomics
• Non-coding RNA research
• Phenotype-genotype relationships
• +۷ مورد دیگر

Associate Professor Jean (Jiayu) Wen holds positions at The Australian National University (ANU), including Group Leader of The Wen Group, ARC Future Fellow, and Deputy Director of The Shine-Dalgarno Centre for RNA Innovation. She specializes in computational and molecular biology, focusing on RNA regulation, gene expression, and cancer genomics. Her affiliations include ANU’s Division of Genome Sciences and Cancer, and the Centre for Computational Biomedical Sciences. Education: BEng in Electronic Engineering (Beijing), MSc in Computer Science (Lakehead University), PhD in Computational Biology (ANU). Postdoctoral training at Copenhagen University and Memorial Sloan-Kettering Cancer Center. Research interests span RNA structures, microRNA biogenesis, transcriptome dynamics, and epigenetic regulation. Her work addresses intragenomic conflicts, cancer mechanisms, and neural development. Notable projects include RNA-based machine learning models for RNA-RNA interactions and immune cell differentiation studies. Publications highlight contributions to RNA interference pathways, tumor development, and Drosophila genetics. Awards include the ARC Future Fellowship. She leads interdisciplinary teams advancing computational and experimental approaches in genomics and systems biology.

• RNA Biology
• Computational Biology
• MicroRNA Regulation
• +۵ مورد دیگر

Associate Professor Timothy Bredy is a leading figure in cognitive neuroepigenetics at the Queensland Brain Institute (QBI) , focusing on how epigenetic modifications and RNA dynamics regulate fear-related memory and psychiatric disorders like PTSD. His research explores the interplay between environmental experiences and genomic activity, particularly through non-coding RNA and DNA methylation. University: University of Queensland School: Faculty of Health, Medicine and Behavioural Sciences Role: Professorial Research Fellow and Group Leader Research Interests span epigenetic mechanisms in memory formation, RNA modifications in synaptic plasticity, and therapeutic applications for anxiety disorders. He pioneered discoveries linking dynamic DNA structures (e.g., G-quadruplexes) and RNA methylation to memory stability. Recent Work includes studies on RNA-based therapeutics, stress-induced epigenetic inheritance, and synaptic long noncoding RNA activity. His scientific awards encompass NHMRC and ARC grants for neuroepigenetics research. Key Collaborators: Paul Marshall, Esmi Zajaczkowski Labs: Bredy Laboratory at QBI

• Epigenetics
• Fear-Related Memory
• RNA Biology
• +۶ مورد دیگر

Professor Shan Rajendra is a distinguished researcher in the Faculty of Medicine at the University of New South Wales, specializing in gastroenterology with a particular focus on the relationship between human papillomavirus (HPV) and esophageal pathologies. His work is conducted through NSW Health in Liverpool, NSW, where he leads research investigating the infectious causes of gastrointestinal cancer with special emphasis on Barrett's oesophagus. Professor Rajendra's research interests center on oesophageal cancer , human papillomavirus , Barrett's oesophagus , and the Barrett's metaplasia-dysplasia-adenocarcinoma sequence . His laboratory employs histopathology and molecular biology techniques to investigate the mechanisms by which high-risk HPV contributes to esophageal carcinogenesis. A significant contribution to the field was his world-first demonstration of the strong association between transcriptionally active high-risk HPV and both Barrett's dysplasia and oesophageal adenocarcinoma, with increasing viral load correlating with greater disease severity. His publication record includes 53 journal articles, 10 conference papers, and 1 book chapter, reflecting substantial contributions to understanding HPV's role in esophageal cancer development. The research has important implications for potential vaccination strategies against a subset of esophageal cancers. Professor Rajendra maintains active clinical and research connections through his work at NSW Health, with his findings contributing to both basic science understanding and potential clinical applications in cancer prevention and early detection.

• Gastroenterology
• Hepatology
• Oesophageal cancer
• +۳ مورد دیگر

Robert White is a Senior Lecturer at the UWA Medical School's MD Education Unit, specializing in medical education and neurobiology. He coordinates units such as IMED1001/IMED3004/APHB5505 and oversees physiology teaching across multiple programs. His research focuses on skeletal muscle biology, neuroprotective mechanisms, and muscular dystrophy. Key areas include gene expression changes in neurons under disease-like insults and the role of transcription factors like Pax6. Collaborations with institutions like Raine Medical Research Foundation highlight his work's translational impact. Teaching Roles: Physiology Coordinator for DENT4121/PODI4111/IMED4443 Research Interests: Autophagy, mitochondrial function, and glucocorticoid effects on muscle Recipient of 13 awards including the 2024 Pre-Clinical Teacher of the Year and multiple UWA Excellence in Teaching Awards. His work aligns with UN SDG goals for health and well-being. Funding Highlights: AU$100k Raine Priming Grant (2012-2014) for Pax6 neuroprotective studies Public Engagement: Delivered lectures on nerve cell protection mechanisms

• Medical Education
• Neurobiology
• Muscular Dystrophy
• +۳ مورد دیگر

Professor Jinyan Li is an Adjunct Professor at the University of Technology Sydney's Data Science Institute, where he leads the Bioinformatics Program. His research develops computational methods for genomic analysis, protein interaction prediction, and biomedical data mining. Educational background: PhD in Computer Science (University of Melbourne) M.Eng in Computer Engineering (Hebei University of Technology) B.Sc in Applied Mathematics (National University of Defense Technology) Research spans: Genomic error correction algorithms Protein binding prediction Single-cell multi-omics analysis CRISPR design optimization Machine learning in bioinformatics With 140+ journal publications and 100+ conference papers, his work appears in leading venues including Bioinformatics, Nucleic Acids Research, and IEEE TKDE.

• Bioinformatics
• Genomics
• Machine Learning
• +۲ مورد دیگر

Nicola Armstrong is a Professor at Curtin University in Western Australia, where she serves in the School of Electrical Engineering, Computing and Mathematical Sciences within the Faculty of Science and Engineering. She is currently the Discipline Lead for Mathematics and Statistics (2024-25) and serves as president of the Western Australian branch of the Statistical Society of Australia. Dr. Armstrong received her PhD from the Department of Statistics at UC Berkeley. Her academic journey has taken her from postdoctoral work in the Netherlands to positions at the Netherlands Cancer Institute as a senior statistician and the Garvan Institute as a senior bioinformatics officer before joining Curtin University. Her research spans multiple disciplines at the intersection of statistics, genomics, and biomedical science. Dr. Armstrong has made significant contributions to: Development of statistical methodology for genomic analysis Application of statistics to cancer research Studies of healthy ageing and dementia Genome-wide association studies (GWAS) Epigenetics and biomarker research Analysis of her recent publications reveals a strong focus on the genetic and epigenetic factors influencing brain structure, cognitive function, and age-related diseases. Her work often involves large-scale collaborative efforts through international consortia, particularly in the areas of neuroimaging genetics and dementia research. Many of her recent studies employ multi-omics approaches to understand the complex interplay between genetic variation, environmental factors, and disease outcomes. Dr. Armstrong actively contributes to the academic community through her teaching of statistics and data science courses at both undergraduate and postgraduate levels, including STAT1006 Regression and Non-parametric Statistics, STAT3001 Statistical Modelling, STAT4002 Introduction to Applied Statistics, STAT5009 Decision Methods and Predictive Analytics, and ACTL4003 Predictive Analytics Principles.

• Applied Statistics
• Data Science
• Genetics
• +۷ مورد دیگر

Dr. Jazmina Gonzalez Cruz is a Senior Research Fellow at the Frazer Institute, University of Queensland, leading the Cancer Immunology and Therapy group. Her research focuses on immunotherapies for virally associated cancers and skin carcinomas, utilizing high-throughput technologies like 10X Genomics and Nanostring DSP. She holds a PhD in Molecular Biology with honors from the National Centre of Biotechnology, Spain, and received postdoctoral training at Heinrich Pette-Institute, Germany. Her work explores T-cell regulation, cytokine immunocomplexes, and tumor microenvironment modulation. Current projects include spatial-omics profiling of head and neck cancers to develop personalized therapies. She collaborates internationally with institutions like Monash University and Technical University of Denmark. Honors and Awards: Garnet Passe & Rodney Williams Memorial Foundation Grant (2019-2023) UQ Postdoctoral Fellowship (2016) Bayer-Humboldt Foundation Fellowship (2013) EEE Department Ph.D. Scholarship

• Cancer Immunology
• Vaccine Development
• Immunotherapy
• +۳ مورد دیگر

Dr. Garima Bhatia is a Research Fellow at the Australian National University's Research School of Biology within the Division of Plant Sciences. She is an active member of the Pogson Group focusing on chloroplast-to-nuclear signaling mechanisms related to light, drought, and carotenoid pathways. Her office is located in Room 1.028, Level 1 of the Linnaeus Building. Her research centers on molecular plant-pathogen interactions, with specialization in grapevine ( Vitis vinifera ) defense mechanisms against powdery mildew ( Erysiphe necator ) and downy mildew ( Plasmopara viticola ). She employs genome-wide approaches to study NBS-LRR gene families and long non-coding RNAs (lncRNAs) in disease resistance and abiotic stress responses. Her work extends to Brassica juncea (Indian mustard) for heat and drought tolerance mechanisms. Analysis of her 9 publications (2017-2021) reveals consistent focus on plant molecular genetics, with 60% of output addressing fungal pathogen resistance through genomic and transcriptomic approaches. Key trends include lncRNA-mediated regulatory networks (44% of publications) and genome-wide characterization of defense gene families (33%). Dr. Bhatia is registered to supervise research students but no specific advisees are listed in available records. She maintains an active research profile with 333 Scopus citations and an h-index of 9. Her laboratory work within the Pogson Group integrates chloroplast signaling pathways with nuclear gene expression during environmental stresses, utilizing advanced genomic techniques to dissect plant immune responses.

• Plant Pathology
• Molecular Plant-Microbe Interactions
• Grapevine Genetics
• +۳ مورد دیگر

Dr Gonzalo del Monte Nieto is a Senior Research Fellow at the Australian Regenerative Medicine Institute (ARMI) and Victorian Heart Institute (VHI) at Monash University. His research focuses on understanding molecular mechanisms and developmental processes in heart development, with applications to congenital heart disease and cardiac regeneration. He holds a PhD in Molecular Biology from the Autonomous University of Madrid (2011) and has held academic positions including Con-joint Senior Lecturer at UNSW (2015–2018) and postdoctoral roles at the Victor Chang Cardiac Research Institute (2011–2018). Education : PhD in Molecular Biology, Autonomous University of Madrid (2011) Masters in Molecular Biology, Autonomous University of Madrid (2007) Bachelor of Biology, Autonomous University of Madrid (2005) Research Interests : Dr del Monte Nieto's work integrates developmental biology with clinical applications, particularly in congenital heart disease and regenerative medicine. Key areas include: Notch signaling pathways in cardiac development ECM dynamics and cardiac trabeculation Computational modeling of heart development Organ-on-chip technologies for cardiac research Grants & Projects : 2024: Company of Biologist Conference Grant (Chief Investigator) 2021: NHMRC Project Grant on Endocardial Sprouting (Chief Investigator) 2019: National Heart Foundation Grant on Cardiac Development Models (Primary Investigator) Labs & Teams : He leads a team focused on cardiac regeneration and developmental biology at ARMI. Collaborations include projects with Prof Richard Harvey’s lab and international institutions.

• Developmental Biology
• Cardiovascular Development
• Congenital Heart Disease
• +۳ مورد دیگر

Dr. Charles Bailey is a Senior Research Fellow at the University of Sydney's Central Clinical School, Department of Medicine, and an affiliated researcher at the Centenary Institute of Cancer Medicine & Cell Biology. His work focuses on cancer biology, epigenetics, and molecular mechanisms underlying genetic diseases. Dr. Bailey leads projects investigating CTCF protein functions in cancer, alternative splicing regulation, and therapeutic targeting of cancer-related pathways. Research Interests: Dr. Bailey's research spans cancer epigenetics (particularly CTCF and chromatin remodeling), gene therapy development, protein-protein interaction networks, and molecular mechanisms of tumor suppression. His work combines experimental models (mouse and cell cultures) with clinical data analysis to bridge basic science and translational medicine. Recent Directions: His articles from 2023 highlight clinical trials for novel cancer drug combinations (e.g., olaparib/durvalumab) and mechanisms of embryo development. Earlier work revealed critical roles for CTCF in genome regulation, while 2022 studies advanced understanding of NuRD complex interactions and lens development pathways. Grants & Awards: Recipient of multiple grants including Tour de Cure's Pioneering Research Awards (2023, 2022, 2021) and Cancer Council NSW support. Projects focus on exploiting genomic vulnerabilities in pancreatic/endometrial cancers and developing gene therapy delivery systems. Collaborations: Active collaborations across Sydney's medical research community, including work with Prof. John Rasko on gene therapy vectors and Prof. Michelle Semsarian on heart disease mechanisms.

• Cancer
• Cell Biology
• Genetics
• +۳ مورد دیگر

Professor Richmond Jeremy is a distinguished academic and clinician at the University of Sydney, serving as Professor of Medicine within the Central Clinical School. He holds multiple leadership positions including Head of School for the Central Clinical School, Associate Dean of the Faculty of Medicine, and Pro-Vice Chancellor of the University. Clinically, he serves as a Consultant Cardiologist at Royal Prince Alfred Hospital and Strathfield Private Hospital, and is the Clinical Director of the Marfan and Aortic Disease Clinic. University of Sydney - Professor of Medicine, Central Clinical School Royal Prince Alfred Hospital - Consultant Cardiologist Cardiac Society of Australia and New Zealand - President Royal Australian College of Physicians - Chair, Specialties Board Heart Lung and Circulation - Editor in Chief Professor Jeremy's research focuses on cardiovascular disease, particularly inherited heart conditions and aortic diseases such as Marfan syndrome, Loeys-Dietz syndrome, and bicuspid aortic valve disorders. His work spans cardiovascular genetics, imaging, hemodynamics, and tissue banking for aortic diseases. His laboratory investigates genetic mutations, epigenetic modifiers, and biomechanical properties of the aorta. Analysis of Professor Jeremy's 15 most recent publications reveals a consistent focus on genetic aortopathies, with particular emphasis on comparative clinical outcomes across different syndromes, molecular mechanisms of disease progression, and innovative approaches to risk stratification. His work increasingly incorporates advanced imaging techniques and molecular biology to understand the pathophysiology of aortic diseases. RT Hall Prize for Research, Cardiac Society of Australia and New Zealand Ralph Reader Prize for Research, Cardiac Society of Australia and New Zealand Yvonne Ahlmgren Research Award, National Heart Foundation of Australia Professor Jeremy actively supervises Honors and PhD students in cardiology and aortic surgery research. His research program has been supported by multiple NHMRC and National Heart Foundation grants, including the 2016 NHMRC Project Grant 'Beyond the tape measure' focusing on flow dynamics in aortic dilation. He leads several international collaborations through the Montalcino Aortic Consortium and maintains research partnerships with institutions in Belgium, Finland, and the United States. His laboratory work is centered at the Baird Institute for Aortic Research, where his team investigates basic science aspects of aortic disease including genetics, proteomics, cell signaling, and pathology. The group maintains a tissue bank for genetic aortopathies and conducts clinical trials on aortic disease management.

• Cardiovascular disease
• Inherited heart disease
• Aortic disease
• +۵ مورد دیگر