Margot Damaser, PhD is a Senior Rehabilitation Career Scientist at the Louis Stokes Cleveland VA and Principal Investigator of the Urological Biomechanics Laboratory at Cleveland Clinic's Main Campus. Her research program bridges biomedical engineering and clinical urology to develop innovative treatments for pelvic floor disorders. Dr. Damaser's research focuses on regenerative medicine, tissue engineering, and device development for pelvic floor dysfunction including urinary and fecal incontinence and pelvic organ prolapse. Her laboratory has developed wireless catheter-free monitoring devices for bladder and colon function, and conducts studies on regenerating damaged pelvic tissue using stem cells, electrical stimulation, and elastogenic nanoparticles. Her work combines engineering principles with clinical applications to translate research into practical diagnostic and therapeutic solutions. Dr. Damaser's publication record shows a strong focus on understanding the neural control of bladder function and developing closed-loop neuromodulation systems. Her recent work has explored brain-derived neurotrophic factors, pudendal nerve regeneration, and stem cell therapies for stress urinary incontinence. She has also contributed significantly to ambulatory urodynamics with wireless monitoring technologies that enable long-term physiological data collection. US Patent 10,537,274: Standardized measurement of physiological pressures using an air-charged catheter apparatus (2020) Dr. Damaser collaborates extensively with researchers across multiple institutions and has published in high-impact journals including Nature Reviews Urology, American Journal of Physiology, and Neurourology and Urodynamics. Her laboratory's work has implications for improving diagnosis and treatment of common pelvic floor disorders that significantly impact quality of life, particularly among elderly populations.
