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نمایش ۴۶-۶۰ از ۲٬۱۷۴ استاد راهنما
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عضو هیئت علمی
Pavel P. Kuksa is a Research Assistant Professor in the Department of Pathology and Laboratory Medicine, specializing in bioinformatics, computer science, and functional genomics. His work focuses on high-throughput sequencing analysis, chromatin interaction data, and developing scalable software platforms for genomics research.
Prof. Lars Mägdefessel is a Professor of Vascular Biology at the Technical University of Munich (TUM), leading the Molecular Vascular Biology group within the TUM School of Medicine and Health. His research focuses on non-coding RNAs in vascular diseases, particularly atherosclerosis and aortic aneurysms, using translational approaches for molecular treatment discovery. He holds an MD from Johannes Gutenberg University (Mainz, Germany), completed cardiology clinical training, and postdoctoral research at Stanford University before joining TUM in 2016. Education: MD from Johannes Gutenberg University, Mainz Postdoctoral training at Stanford University, USA Assistant Professor at Karolinska Institute, Sweden Research Interests: Non-coding RNA regulation in vascular pathology Mechanisms of atherosclerotic plaque vulnerability Translational therapies for vascular diseases Advanced aortic aneurysm progression Awards include the ERC Consolidator Grant (2023), Russell Ross Award (2023), and Heisenberg Professorship (2016). His lab is supported by the German Center for Cardiovascular Research (DZHK).
دانشیار
Zhiwei Ye is an Associate Professor in the Department of Pharmacology & Immunology at the College of Medicine, Medical University of South Carolina. His research focuses on redox biology, cancer mechanisms, and drug metabolism with a particular emphasis on mitochondrial function, oxidative stress, and therapeutic resistance. He holds a PhD in Pharmaceutical Science from Katholieke Universiteit Leuven (Belgium, 2009) and prior degrees from Zhejiang University (China). PhD in Pharmaceutical Science, 2009 – Katholieke Universiteit Leuven, Belgium Master in Pharmaceutical Science, 2005 – Katholieke Universiteit Leuven, Belgium Master in Medicine, 2003 – Zhejiang University, China B.S. in Pharmacy, 2000 – Zhejiang University, China Dr. Ye’s research explores how redox regulation impacts cancer progression, drug resistance, and metabolic disorders. His work integrates enzymology (e.g., GSTP, PDI), mitochondrial dynamics, and zebrafish models to study mechanisms like S-glutathionylation, VDAC targeting, and drug-transporter interactions. Recent studies highlight novel therapeutic strategies for hepatocellular carcinoma, melanoma, and myeloma through modulation of redox pathways. Publications emphasize translational research bridging basic biology and clinical applications, including drug development (e.g., Telintra) and understanding treatment resistance in malignancies. His work also addresses metabolic disease mechanisms, such as hepatic steatosis and drug-induced renal toxicity. No scientific awards explicitly mentioned in provided texts. Active in grant-funded research areas like cancer biology and redox signaling. Collaborates on projects involving drug-transporter profiling in hepatocytes and cellular stress responses.
Dr. Ramanjulu Sunkar is a Regents Professor in the Department of Biochemistry & Molecular Biology at Oklahoma State University. He leads research on epigenetic and small RNA mechanisms in plant stress responses, focusing on gene regulation under drought, heat, and abiotic stresses. His work integrates genomic tools like ChIP, RNA sequencing, and CRISPR/Cas9 to study stress tolerance in crops. Education: B.Sc. (Sri Venkateswara University), M.Sc. and Ph.D. (Sri Krishnadevaraya University, India), followed by postdoctoral research at the Weizmann Institute (Israel), University of Bonn (Germany), and UC Riverside (USA). He joined Oklahoma State University in 2006, becoming Professor in 2016 and Regents Professor in 2024. Research Interests: Epigenetic modifications (DNA methylation, histone changes), microRNA-guided gene regulation, plant stress memory, and translational control mechanisms. His lab uses model systems like Arabidopsis, rice, and sorghum to study adaptive responses to environmental challenges. Grants: Over 15 grants, including USDA-funded projects on microRNA roles in photosynthesis, epigenetic control of drought tolerance, and systems genetics in rice. NSF-EPSCoR support for bioenergy research. Teaching: Courses include 'Plant Biochemistry,' 'Epigenetics,' and graduate supervision through research credits. Developed new courses on plant stress biology and molecular techniques. Labs/Teams: Leads a research group focused on epigenomics and RNA regulation in plants. Collaborates internationally on projects like the Arabidopsis transcriptome and stress memory mechanisms.
Professor Annette Byrne is a leading academic at RCSI University of Medicine and Health Sciences , where she serves as Professor of Physiology and Head of the Precision Cancer Medicine (PCM) Group. She has held this position since 2019 after progressing through roles as Lecturer (2008), Senior Lecturer (2013), and Associate Professor (2017). Her research focuses on precision medicine approaches for colorectal and brain cancers , integrating multi-modality molecular imaging , Next Generation Sequencing , and patient-derived xenograft models . PhD in Cell Biology (University of York, 1999) John Kerner Fellowship in Gynaecologic Oncology (UCSF, 1999-2001) Scientist at Pharmacyclics Inc. (2001-2003) Senior Scientist at Angion Biomedica Corp. (2003-2005) Principal Investigator at UCD Conway Institute (2005-2008) Her research interest lies in precision cancer medicine , particularly elucidating predictive biomarkers (genomic, transcriptomic, proteomic) and identifying novel therapeutic targets . Key methodologies include radiomics , fluorescence-guided surgery , and systems modeling of apoptosis pathways. She has pioneered Ireland's first Tumour Xenograft Facility and Translational In Vivo Imaging Centre . Recent publications highlight her work on cross-species radiomics , cell-free DNA analysis , and glioblastoma microenvironment subtyping . Her Marie Curie networks (Gliotrain, Glioresolve) and COLOSSUS project have trained 25+ PhD researchers in brain cancer therapeutics. Over €45M in national/international grants Member of Royal Irish Academy (2025) Highly cited in Cancer Discovery , Annals of Oncology , and Nature journals She supervises multiple PhD candidates and leads the RCSI Precision Cancer Medicine Group , which utilizes computational approaches and molecular imaging to improve cancer treatment outcomes. Her GLIORESOLVE and EDIReX projects focus on tumor microenvironment manipulation and distributed PDX infrastructure.
Juan-Manuel González-Rosa is an Assistant Professor in the Department of Biology at Boston College, where he leads a research program focused on heart development and regeneration. He utilizes zebrafish as a model organism to investigate the molecular and cellular mechanisms that govern cardiac repair, with particular interest in fibrosis, inflammation, and polyploidy. Ph.D. in Molecular Biology, Spanish National Center for Cardiovascular Research and Universidad Autónoma de Madrid Postdoctoral training at Massachusetts General Hospital and Harvard Medical School Faculty member at Boston College since June 2019 His research centers on understanding why the human heart has limited regenerative capacity compared to zebrafish, which can fully regenerate their hearts after injury. His lab investigates how polyploidization in cardiomyocytes limits regeneration and aims to identify therapeutic targets for promoting heart repair after myocardial infarction. Using genetic tools and injury models in zebrafish, his team studies cardiac and liver regeneration, extracellular matrix dynamics, and molecular pathways of tissue repair. The recent publications reflect a strong trend in regenerative biology, particularly in modeling organ injury and repair in zebrafish. Key themes include the development of cryoinjury models for heart and liver, analysis of collagen dynamics in fibrotic remodeling, and the use of genetic tools like CRISPR for targeted cardiomyocyte manipulation. These studies span developmental biology, molecular cardiology, and translational regenerative medicine. Scientific awards and recognitions include: EMBO Long-Term Postdoctoral Fellowship Funds for Medical Discovery Award from ECOR-MGH American Heart Association Career Development Award Dr. González-Rosa has secured competitive funding to support his research program, enabling his lab to pursue fundamental questions in cardiac regeneration. While current information does not list specific advisees, his role as a principal investigator suggests active mentorship of graduate and undergraduate researchers. His work contributes to broader efforts in regenerative medicine and has implications for treating heart disease in humans. His lab is involved in developing and applying innovative zebrafish models for organ regeneration and transplantation research, positioning his team at the intersection of developmental biology, cardiovascular science, and biomedical innovation.
Dr. Steven Jacobsen is a Professor in the Molecular, Cell, and Developmental Biology Department at the University of California, Los Angeles (UCLA), where he leads the Jacobsen Lab. His work focuses on epigenetic inheritance and gene regulation in Arabidopsis thaliana and mammalian stem cells, utilizing genetic screens, genomics, epigenomics, and biochemical approaches. The lab also pioneers CRISPR-mediated genome editing techniques. University: University of California, Los Angeles Department: Molecular, Cell, and Developmental Biology Research Interests: Jacobsen's research spans multiple interconnected domains in epigenetics, including DNA methylation patterning, histone modification interplay, and transposable element silencing. His team investigates how chromatin structure influences gene expression and epigenetic inheritance, with applications from plant development to human health. Key areas include: CRISPR-based epigenetic modifications RNA-directed DNA methylation (RdDM) mechanisms Chromatin compaction via MORC proteins Histone variant functions in methylation Transposon control in plant genomes Comparative epigenomics across species Advising Legacy: Over two decades, Dr. Jacobsen has mentored 21 former lab members who now hold academic and industry positions globally, including professors at Chinese Academy of Sciences, University of Georgia, and Southern University of Science & Technology. His lab's publications reveal a consistent focus on DNA methylation dynamics, chromatin remodeling, and small RNA pathways, with recent work emphasizing CRISPR innovations and structural insights into epigenetic regulators.
Christopher S. Sullivan is a Professor in the Department of Molecular Biosciences within the College of Natural Sciences at the University of Texas at Austin. He directs an active research laboratory focused on viral non-coding RNA biology and host-pathogen interactions, with continuous funding evidenced by publications spanning 2005-2025. His work bridges molecular virology, immunology, and RNA biology through investigations of tumor viruses and host defense mechanisms. Research interests center on the role of non-coding RNAs in viral infection and host defense pathways, with particular emphasis on viral microRNAs , RNA interference mechanisms , and host-pathogen coevolution . His lab studies diverse virus families including Polyomaviridae, Herpesviridae, Retroviridae, and avipoxviruses, with key discoveries regarding viral miRNA functions in tumorigenesis and immune evasion. Research approaches integrate molecular virology, next-generation sequencing, and computational analysis to dissect RNA-based regulatory networks. Publications reveal consistent focus on viral non-coding RNA functions, particularly how viruses exploit host RNA machinery (notably DUSP11 phosphatase) to modulate immune responses. Recent work (2021-2025) expands into viral shedding dynamics, SARS-CoV-2 diagnostics, and circular RNA biology in polyomaviruses, demonstrating evolving yet cohesive research trajectory in RNA-virus interactions. Scientific contributions include: Pioneering identification of viral microRNAs across multiple virus families Discovery of DUSP11's critical role in RNA triphosphate regulation during infection Mechanistic insights into viral evasion of RNAi and innate immunity Development of novel RNA-based detection methods The Sullivan lab maintains active collaborations through the Center for Systems and Synthetic Biology, John Ring LaMontagne Center for Infectious Disease, and Interdisciplinary Life Sciences Graduate Programs. Lab culture emphasizes collective scientific inquiry with stated mission to 'increase understanding of pathogen-host interactions while enjoying the company of fellow lab members.' Current research directions include viral exploitation of RNA modification pathways and identification of novel host defense mechanisms using viruses as 'molecular divining rods.'
G. Petur Nielsen, MD is a Professor of Pathology at Harvard Medical School and serves as Subspecialty Head, Bone and Soft Tissue Pathology at Massachusetts General Hospital . With a clinical focus on bone and soft tissue tumors, his expertise spans diagnostic pathology, molecular genetics of neoplasms, and ancillary testing applications. Research interests center on Pathology and biology of bone/soft tissue tumors Molecular genetics of bone and soft tissue neoplasms Chordoma and sarcoma research Epithelioid vascular tumor differentiation Mesenchymal tumors of the female genital tract His work includes landmark studies on tumor misdiagnosis rates, immunohistochemical profiling, and genomic analysis of chordomas. Scientific contributions appear in leading journals like Nature and American Journal of Surgical Pathology , with major emphasis on Molecular tumor classification Mutational signature analysis Translational oncology Diagnostic accuracy improvement Genomic instability mechanisms
Professor Ghazaleh Tabatabai serves as Head of Department for Clinical and Experimental Neuro-Oncology at the Hertie Institute for Clinical Brain Research, University of Tübingen. She leads a multidisciplinary research group focused on translational neuro-oncology with active collaborations through the German Glioma Network, German Cancer Consortium (DKTK), European Organisation for Research and Treatment of Cancer (EORTC), European Association of Neuro-Oncology (EANO), and International Consortium on Meningioma (ICOM). Her research program centers on molecular mechanisms of tumorigenesis, therapy resistance, and treatment-induced vulnerabilities in nervous system tumors. The laboratory employs CRISPR screening technologies, molecular profiling, and preclinical models to identify therapeutic targets, with particular expertise in glioma and meningioma biology. Current projects span from discovery through validation to clinical application, including phase I/II trials of novel therapies such as CureVac's mRNA vaccine candidate CVGBM. Recent publications demonstrate leadership in molecular classification of meningiomas, CRISPR-based target discovery, immunotherapy development, and clinical trial design. Her work on the TRACE app for patient-reported outcomes and the PRIDE trial for dose-escalated radiation therapy represents significant clinical translation efforts. The 2024-2025 publication record shows strong productivity with high-impact papers in Neuro-Oncology, Nature Medicine, and Genome Biology. Elected spokesperson of the DFG Board for Neuroscience (2024) Active participation in EANO guideline development Leadership in multiple international consortia including ICOM Principal investigator for clinical trials including N2M2/NOA-20 umbrella trial Professor Tabatabai mentors a large research team including PhD students, medical doctoral candidates, and postdoctoral researchers. Her laboratory maintains active clinical collaborations across neurosurgery, radiation oncology, and medical oncology departments. She is featured in the 'Key To My Research' podcast discussing tumor intelligence and regularly presents at major neuro-oncology conferences including ASCO, EANO, and SNO.
Dr. David T Wong is a Professor in the Dentistry Department and Head and Neck Surgery at the University of California Los Angeles. With dual appointments across departments, he leads groundbreaking research at the intersection of molecular biology, diagnostics, and oral medicine. His work has established UCLA as a global leader in salivary diagnostics research. Dr. Wong earned his BSc in Biochemistry from Simon Fraser University in 1977, followed by a DMD in Dental Medicine from the University of British Columbia in 1981. He completed advanced training at Harvard with a DMSc in Molecular Biology (1985) and a Certificate in Oral Pathology from Harvard School of Dental Medicine (1985). His research focuses on salivary diagnostics for disease detection, particularly in oral/head and neck cancer. Dr. Wong pioneered the field of "Salivaomics" - the comprehensive study of saliva as a diagnostic fluid containing proteomic, genomic, transcriptomic, metabolomic, and microbiome information. His laboratory spearheads high-throughput technologies to identify genomic and proteomic determinants of oral cancer progression, with emphasis on developing non-invasive diagnostic tools. Key areas include liquid biopsy technologies (particularly saliva-based), extracellular RNA communication, and the development of point-of-care diagnostic devices like the Oral Fluid NanoSensor Test (OFNASET). Analysis of his recent publications reveals a strong trend toward clinical translation of salivary biomarkers, with increasing focus on Sjögren's Syndrome diagnostics, liquid biopsy applications for cancer detection, and the development of novel technologies like EFIRM (Electric Field-Induced Release and Measurement) for ultra-sensitive detection of biomarkers in saliva. His work bridges basic science with clinical applications, particularly in early cancer detection and monitoring. Dr. Wong has received extensive NIH funding as Principal Investigator for numerous projects, including multiple R01, U01, and T32 grants focused on salivary diagnostics, oral cancer biomarkers, and dentist-scientist training programs. His research funding spans over two decades, demonstrating sustained impact and relevance in the field. He leads the Wong Lab, which functions as an interdisciplinary research hub bringing together experts in molecular biology, engineering, dentistry, and oncology. The lab has been instrumental in establishing saliva as a viable biofluid for liquid biopsy applications, particularly for detecting actionable mutations in human cancers. Current research directions include refining EFIRM technology for clinical implementation and expanding the applications of salivary diagnostics to systemic diseases beyond oral conditions.
Rodrigo Fernandez Gonzalo is a Docent (Associate Professor) in Physiology and Principal Researcher at the Division of Clinical Physiology, Department of Laboratory Medicine, Karolinska Institutet. He leads the Space and Environmental Physiology research group focusing on skeletal muscle adaptation under various conditions including microgravity, aging, disease, and exercise. His research interests span skeletal muscle physiology, space physiology, and environmental physiology, with particular expertise in how skeletal muscle interacts with other physiological systems. His work employs diverse methodologies including human clinical studies, animal models, and cellular models to investigate functional, metabolic, morphological, molecular, and neural adaptations. Analysis of his recent publications reveals a strong focus on space physiology applications, particularly how microgravity affects skeletal muscle and immune systems, along with translational applications for clinical populations like those with cerebral palsy. His research integrates molecular analysis, imaging techniques, and physical performance outcomes to develop countermeasures for spaceflight effects. 4.5 MSEK funding from the Swedish National Space Agency (2020) Member of European Space Agency's Life Science Working Group (2022-2026) Member of Space Researchers Sweden (2021-) Dr. Fernandez Gonzalo serves as course responsible for Anatomy and Physiology in the nursing program (since 2018) and Advanced Human Physiology Research in the Master's programme in Translational Physiology and Pharmacology (since 2023). He also teaches Human Spaceflight at KTH and participates in the Erasmus Mundus Joint Master in Physiology and Medicine of Humans in Space and Extreme Environments. His laboratory utilizes facilities at Karolinska University Hospital and ANA Futura for human, animal, and cellular studies investigating space exposome effects.
استاد پژوهشی
Zhishan Wang, MD, PhD is a Research Professor in the Department of Pathology at Stony Brook University's Renaissance School of Medicine . His work focuses on environmental carcinogenesis , particularly mechanisms of cancer biology and cancer therapy , with a specialization in metal-induced carcinogenicity. Research Interests: Environmental Carcinogenesis Epigenetic and Epitranscriptomic Mechanisms Tumor Microenvironment Remodeling Metal Toxicity Pathobiology Non-Coding RNA Regulatory Networks Scientific Contributions: Analysis of 15 recent publications reveals expertise in: Metal-Induced Oncogenic Pathways (e.g., NF-κB activation, Hedgehog signaling) RNA Modification Dynamics (m6A, lncRNA-splicing interactions) Stem Cell Plasticity in Carcinogenesis Multi-Carcinogen Synergy Mechanisms Epigenetic-Genotoxic Interplay Transcriptomic Reprogramming by Toxicants
Andreas Matouschek is a Professor in the Department of Molecular Biosciences at the University of Texas at Austin, where he served as Associate Dean for Research and Facilities from 2020-2024. He oversees research support for the College of Natural Sciences, managing over 1 million square feet of research space across multiple campuses. Prior to joining UT Austin in 2012, he spent 15 years at Northwestern University where he held leadership roles including Program Leader for Cancer Cell Biology in the Robert H. Lurie Comprehensive Cancer Center. Matouschek received his education at prestigious institutions: Diplom in Biology from Ludwig-Maximilians-University in Munich (1990), Ph.D. in Chemistry from Cambridge University (1992), and was an EMBO Fellow at the Biocenter of the University of Basel. His research focuses on the mechanisms of protein machines, particularly protein folding, unfolding, and degradation. The Matouschek Lab investigates the biochemical mechanisms of the Ubiquitin Proteasome System (UPS) in physiologically relevant contexts, with the goal of understanding how cellular processes are regulated through protein degradation. The lab employs diverse experimental techniques including protein engineering, quantitative biochemical assays, cell biology, genome-scale screens, and single molecule biophysics. Analysis of his recent publications reveals a consistent focus on proteasome structure and function, substrate recognition mechanisms, and the regulation of protein degradation. His work has significant implications for understanding cellular regulation and developing therapeutic approaches targeting the ubiquitin-proteasome system. As Associate Dean, he managed a team of 17 full-time staff supporting research across the College of Natural Sciences, including facilities spanning from the McDonald Observatory in West Texas to the Marine Science Institute on the Gulf Coast. His laboratory continues to make significant contributions to understanding the fundamental mechanisms of protein degradation and its implications for cellular function and disease.
استادیار
Gabriella Casalino is an Assistant Professor at the University of Bari Aldo Moro, Department of Computer Science, and a key researcher at CILAB - Computational Intelligence Lab. Her work focuses on Computational Intelligence methods for interpretable data analysis, particularly in eHealth, Data Stream Mining, and eXplainable Artificial Intelligence (XAI) within medical and educational domains. She has contributed to innovative approaches in smartphone-based health monitoring, fuzzy logic applications, and remote vital sign detection via photoplethysmography. Education : Ph.D. in Computer Science, with advanced training at institutions like Universitat de Girona and Université de Mons. Research Trends : Recent publications highlight applications of evolving granular computing, neuro-fuzzy systems, and explainable AI in hypertension prediction, bipolar disorder monitoring, and educational data analysis. Key subfields include remote health monitoring, medical data streams, and hybrid AI models. Grants : Research funded by AIRC (Italian Cancer Research Foundation), focusing on computational methods for healthcare challenges. Labs & Collaborations : Active in CILAB, collaborating on projects involving mHealth solutions, cardiovascular risk assessment, and intelligent educational systems.
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