جست‌وجوی استاد و پژوهشگر

Abdelrahman Y. Foudaمشاهده پروفایل

استادیار

• Neuroscience
• Ophthalmology
• Immunology
• +۵ مورد دیگر

Abdelrahman Y. Fouda is an Assistant Professor in the Department of Pharmacology and Toxicology at the University of Arkansas for Medical Sciences (UAMS) College of Medicine. He leads the Fouda Lab, which focuses on central nervous system (CNS) injury mechanisms, particularly in the retina and brain. His research employs molecular, cellular, and animal models to study diseases like diabetic retinopathy, traumatic optic neuropathy, and stroke. Key areas include myeloid cell modulation (macrophages/microglia) and neurovascular repair. Dr. Fouda’s lab is funded by NIH/NEI and has access to advanced retinal imaging and electrophysiology equipment. Education: B.Pharm, Cairo University School of Pharmacy (2002-2007) Ph.D., University of Georgia Clinical and Experimental Therapeutics (2011-2015) Postdoctoral training at University of Georgia (2015-2016) and Augusta University (2016-2021) Research interests emphasize immune cell interactions in CNS diseases, targeting arginase pathways and HDAC3 to promote reparative phenotypes. Recent grants include the UAMS Hornick Stroke Award (2024-2025) and NIH R00 EY029373 (2021-2024). His lab’s innovations include pegylated arginase 1 therapies and proteomic analysis for retinal injury biomarkers. Key Awards: AHA Postdoctoral Fellowship (2018-2020) NIH K99/R00 Pathway to Independence Award Labs/Teams: Fouda Lab Group with specialized equipment for in vivo retinal imaging (Bioptigen SDOIS) and electroretinography (Celeris ERG). Dr. Fouda’s work bridges bench-to-bedside translational research, aiming to develop therapies for retinal and CNS injuries through precise molecular targeting.

Huiliang Zhangمشاهده پروفایل

استادیار

• Cardiac Aging
• Mitochondrial Biology
• Stem Cell Therapy
• +۳ مورد دیگر

Huiliang Zhang, Ph.D., is an Assistant Professor in the Department of Pharmacology and Toxicology at the University of Arkansas for Medical Sciences (UAMS) College of Medicine. His office is located in Biomed 1, B306D, and his research lab operates from Biomed 1, B331. He earned his doctorate in Biophysics from Peking University in 2014, followed by postdoctoral training at the University of Washington. Dr. Zhang's research centers on cardiac aging mechanisms, with emphasis on mitochondrial dysfunction—particularly elevated proton leak—and strategies to reverse age-related cardiac decline. His work explores mitochondrial rejuvenation using compounds like SS-31 and stem cell therapies in preclinical models. Key research areas include: Mitochondrial bioenergetics in aging cardiomyocytes Proton leak regulation and metabolic restoration Stem cell applications for cardiac repair Vascular aging and inflammaging pathways His recent publications (2020-2025) demonstrate evolving focus from mitochondrial respiration mechanics to therapeutic interventions for cardiac/vascular aging, with increasing emphasis on proteomics, iPSC models, and metabolic modulation. Publication keywords cluster around mitochondrial dynamics, cardiac metabolism, and aging biomarkers. Awards & Grants: American Heart Association Career Development Award (2019-2022): Mechanisms of mitochondrial rejuvenation for diastolic dysfunction Bronson Foundation Intramural Grant (2022): Human iPSC-derived cardiomyocyte senescence Glenn/AFAR Postdoctoral Fellowship (2018): SS-31 reversal of mitochondrial dysfunction Dr. Zhang directs an active research lab investigating mitochondrial pathophysiology and maintains collaborations with cardiovascular and aging research consortia. He serves as an AHA study section member and has published over 30 peer-reviewed articles.

• Prion diseases
• Multiple sclerosis
• Clinical neurology
• +۴ مورد دیگر

Professor Simon Hawke is an Honorary Professor in the Department of Pathology at the University of Sydney's School of Medical Sciences. He is a member of the Charles Perkins Centre and leads research into prion diseases, multiple sclerosis, and autoimmune neurology. His work focuses on immune system modulation to inhibit prion replication and neurodegenerative processes, with notable contributions to understanding blood-brain barrier dynamics and B-cell dysfunction in multiple sclerosis. Research interests include prion protein immunotherapy, autoimmune mechanisms in neurodegeneration, and translational therapies targeting neuroinflammation. Key areas of expertise encompass clinical neurology, immunology, and molecular biology of neurodegenerative disorders. His studies explore monoclonal antibodies as treatments for prion diseases and investigate B-cell subsets and cytokine signaling in multiple sclerosis pathogenesis. Publications highlight advancements in cladribine's effects on immune cell migration across blood-brain barrier models, B-cell dysregulation in MS relapses, and biomarkers distinguishing neuromyelitis optica from MS. His work also addresses prion protein glycoform analysis and Sjögren’s syndrome-associated neurological complications. Grants include studies on immunomodulating drugs in MS, fingolimod's impact on lymphocyte migration, and molecular characterization of blood-brain barrier inflammation. Collaborations involve institutions like the Charles Perkins Centre and funding bodies such as Multiple Sclerosis Research Australia and NHMRC. Professor Hawke’s research integrates clinical observations with molecular and cellular techniques, aiming to bridge basic science and translational therapies for neurodegenerative and autoimmune disorders.

Anna Devorمشاهده پروفایل

استاد

• Neuroscience
• Neuroimaging
• Cellular Neuroscience
• +۳ مورد دیگر

Anna Devor is a Professor of Biomedical Engineering at Boston University, with a primary appointment in the Department of Biomedical Engineering and affiliations at the Martinos Center for Biomedical Imaging. She holds a PhD from the Hebrew University of Jerusalem, Israel. Her research focuses on neurovascular imaging, cellular and systems-level neuroscience, and microscopy techniques, particularly in understanding the physiological underpinnings of noninvasive imaging modalities. Key research areas include neuroimaging methodologies, neurovascular coupling, and the development of advanced optical tools for in vivo brain measurements. She has pioneered techniques like two-photon microscopy for oxygen and blood flow studies, and her lab explores applications in aging, exercise physiology, and neural prosthetics. Notable contributions include the Tissue Oxygen Depth Explorer database and advancements in transparent neural interfaces for human organoid studies. Dr. Devor has received the BRAIN Initiative award and Outstanding Teaching accolades. Her work integrates engineering, neurobiology, and clinical insights, with a focus on translational applications. Current projects involve chronic imaging systems, optogenetic studies, and multimodal monitoring of brain organoids in vivo.

Reidun Torpمشاهده پروفایل

دانشیار

• Neuroscience
• Alzheimer's Disease
• Parkinson's Disease
• +۵ مورد دیگر

Reidun Torp is an Associate Professor in Molecular Neuroscience at the University of Oslo's Faculty of Medicine. Her research focuses on neurodegenerative diseases including Alzheimer's and Parkinson's, with particular emphasis on cellular mechanisms and molecular pathology. Research interests center on: Molecular pathology of Alzheimer's disease Astrocyte and microglia dysfunction in neurodegeneration Neurovascular pathology and amyloid deposition Transgenic models of neurodegenerative diseases Neural cell biology and protein mislocalization Neuroprotective strategies and disease mechanisms Her publication trends show consistent focus on: Transgenic mouse models of neurodegeneration Cellular mechanisms of amyloid pathology Astrocyte and microglia dysfunction Neurovascular changes in dementia Dr. Torp leads research within the Molecular Neuroscience group and collaborates extensively with neuropathologists and cellular biologists.

Hari Baskar Balasubramanianمشاهده پروفایل

پژوهشگر

• Pharmacology
• Toxicology
• Autoimmune Diabetes
• +۵ مورد دیگر

Hari Baskar Balasubramanian is a predoctoral researcher at the University of Vienna, Faculty of Life Sciences, Department of Pharmaceutical Sciences, Division of Pharmacology and Toxicology. His work focuses on pharmacological interventions in autoimmune diabetes, diabetic kidney disease, and neurovascular aging. ÖAW DOC Fellowship 2024 Ernst Mach Grant-Worldwide 2023 His research spans pharmacology, immunology, and computational biology, with a focus on: Blood-brain barrier senescence metabolism Targeted delivery of diabetes therapeutics Drug-receptor interactions in fibrotic diseases Genetic polymorphisms in immune signaling Molecular docking of medicinal plant compounds Extracellular ATP in autoimmunity Recent publications emphasize: 2025: Endothelial cell metabolic aging signatures 2024: Nintedanib's novel targets and GLP-1's immunomodulatory role 2023: sCD39/anti-CD3 diabetes reversal and diabetic kidney disease management Collaborations span diabetes immunology, neuropharmacology, and medicinal chemistry networks.

Bart Eggenمشاهده پروفایل

استاد

• Neurosciences
• Cell Biology
• Neuroinflammation
• +۵ مورد دیگر

Prof. Bart Eggen is a Professor in the Department of Biomedical Sciences of Cells & Systems at the University of Groningen's Faculty of Medical Sciences. His research focuses on neuroinflammation, neurodegenerative diseases (e.g., Alzheimer's, multiple sclerosis), and microglial biology. He leads the Molecular Neurobiology section and holds roles on the Scientific Advisory Boards of Alzheimer Nederland and the Dutch Society for MS Research. Key research interests include gene expression regulation, epigenetics, and cellular mechanisms underlying neurodegeneration. Recent work explores microglia's role in synaptic pruning, remyelination, and aging-related inflammation. Eggen has published over 150 peer-reviewed articles and collaborates internationally on projects like the Netherlands Neurogenetics Database (NND). Education: Not explicitly stated in provided texts. Research Highlights: Focuses on microglia dynamics, neuroinflammation, and translational research linking basic biology to neurological disorders. His laboratory investigates cellular senescence in brain aging, epigenetic reprogramming in microglia, and omics approaches to study glial biology. Collaborative projects include brain organoid models for neurodegeneration and glioblastoma research. Eggen's work has implications for developing therapies targeting microglial dysfunction in diseases like Alzheimer's and multiple sclerosis. Awards/Grants: Not explicitly listed in provided texts, though his prolific publication record suggests sustained research funding. He chairs/advises multiple national research initiatives.

• Nitric oxide signaling
• Cardiovascular physiology
• Molecular medicine
• +۷ مورد دیگر

Professor James Leiper is an Honorary Professor in the School of Cardiovascular & Metabolic Health at the University of Glasgow, where he leads research at the Institute of Cardiovascular and Medical Sciences and the BHF Glasgow Cardiovascular Research Centre. His work focuses on translating basic science findings into applications for human health and disease, with particular emphasis on nitric oxide signaling pathways. Originally trained in molecular biology at the MRC Clinical Research Centre, Professor Leiper developed his interest in cardiovascular physiology while working with Professor Patrick Vallance in the Centre for Clinical Pharmacology at UCL. He continued this research as a Programme Leader at the MRC Laboratory for Medical Sciences before joining the University of Glasgow in 2017. Professor Leiper's research centers on understanding the mechanisms that regulate nitric oxide (NO) signaling in health and disease. His laboratory investigates how endogenously produced inhibitors of NO synthesis, particularly through the ADMA/DDAH pathway, might be harnessed therapeutically. His work spans cardiovascular, immune, and central nervous systems, with applications to conditions including hypertension, atherosclerosis, and the cardiovascular collapse seen in septic shock. Rather than directly targeting NO (which has had limited therapeutic success), his research focuses on endogenous regulatory pathways that might facilitate more appropriate regulation of NO production. His recent publications demonstrate a continued focus on nitric oxide signaling pathways, with particular attention to asymmetric dimethylarginine (ADMA) and dimethylarginine dimethylaminohydrolase (DDAH). His work spans multiple disciplines including vascular biology, cardiovascular physiology, and translational medicine, with applications to conditions such as septic shock, hypertension, metabolic disorders, and vascular contributions to dementia. Professor Leiper has secured significant research funding from major organizations including the Medical Research Council (MRC), British Heart Foundation (BHF), and Wellcome Trust, totaling millions of pounds for his research on nitric oxide signaling pathways. His research group has been supported by substantial grants including an MRC Intramural Research Programme Funding award of £2.8 million and multiple British Heart Foundation project grants. Professor Leiper has supervised numerous PhD students and postdoctoral researchers through various funding mechanisms including BHF PhD studentships, MRC Chain Florey Fellowships, and the BHF ICTEM 4-year PhD training scheme. To facilitate translation of his understanding of nitric oxide signaling for healthcare benefit, he established a biotech company backed by venture capital funding to perform clinical trials of new drugs for the treatment of septic shock. His research group collaborates extensively with clinical researchers across multiple disciplines to advance understanding of cardiovascular diseases and their treatment.

• Neuroscience
• Neurodegenerative Disorders
• Vascular Biology
• +۵ مورد دیگر

Berislav V Zlokovic is the Chair and University Professor of Physiology & Neuroscience at the Keck School of Medicine of USC, holding the Mary Hayley and Selim Zilkha Chair in Alzheimer’s Disease Research. He is Director of the Zilkha Neurogenetic Institute and leads the Department of Physiology & Neuroscience. His work focuses on the blood-brain barrier (BBB), Alzheimer’s disease (AD), and stroke, with contributions to understanding BBB dysfunction’s role in neurodegeneration. He has pioneered research on BBB cellular pathways, gene therapy, and imaging techniques, leading to clinical trials for AD and stroke. Zlokovic’s research interests include BBB biology, AD pathogenesis, stroke mechanisms, and biomarkers. He studies APOE4’s impact on cerebrovascular systems and develops therapies using iPSC-derived cells and APC analogs. His work spans transgenic models, human studies, and translational research. His awards include the Potamkin Prize, Javits Award, and recognition as a 'Highly Cited Researcher' for 21 consecutive years. He co-founded ZZ Biotech to advance neurological treatments and serves as a Nobel Prize nominator. His lab integrates molecular, cellular, and translational approaches to address BBB-related disorders.

• Protein Folding
• Membrane Biophysics
• Neurodegenerative Diseases
• +۳ مورد دیگر

Ralf Langen serves as Professor of Physiology & Neuroscience at the University of Southern California's Keck School of Medicine. He directs both the Protein Structure Center at the Zilkha Neurogenetic Institute and the Ph.D. Program in Medical Physiology, while co-directing the Ph.D. Program in Medical Biophysics. His academic leadership spans multiple interdisciplinary programs including the Programs in Biomedical and Biological Sciences and the PEW Scholar initiative. Langen's research centers on protein folding and misfolding dynamics, with specific emphasis on membrane-mediated processes. His laboratory investigates how proteins regulate membrane structure/function through composition, fluidity, and curvature modulation, and conversely how membranes influence protein conformation. A major focus involves pathological protein misfolding in neurodegenerative diseases like Huntington's and Parkinson's, with particular attention to huntingtin exon-1 aggregation mechanisms. His work employs advanced biophysical techniques including site-directed spin labeling, EPR spectroscopy, and computational modeling to resolve structural dynamics at membrane interfaces. Analysis of his publication record reveals consistent contributions to understanding membrane-protein interactions in amyloid formation. His recent work demonstrates how membrane environments alter aggregation pathways, generate toxic oligomers, and influence strain-specific pathology in polyglutamine disorders. Key findings include elucidating the role of post-translational modifications like lysine acetylation in membrane binding, characterizing conformational switching in huntingtin variants, and developing small-molecule inhibitors targeting aggregation. No scientific awards explicitly listed in source material As director of USC's Medical Physiology Ph.D. program and co-director of the Medical Biophysics program, Langen oversees graduate training while maintaining active research mentorship. His laboratory receives funding for structural studies of neurodegenerative disease mechanisms, though specific grants aren't detailed in the source text. The Protein Structure Center under his direction provides critical infrastructure for membrane protein research. Langen's primary research facility operates within the Zilkha Neurogenetic Institute, where his Protein Structure Center specializes in membrane-protein interactions. The center integrates biophysical, biochemical, and computational approaches to study conformational dynamics in disease-related proteins, with particular expertise in spin-labeling techniques for membrane-embedded systems.

Andrew Limمشاهده پروفایل

استادیار بالینی

• Radiation Oncology
• Artificial Intelligence in Medicine
• Brachytherapy
• +۵ مورد دیگر

Andrew Lim, MD, is a Clinical Assistant Professor of Radiation Oncology at the University of Southern California (USC Norris Comprehensive Cancer Center). He specializes in advanced radiation therapies like brachytherapy for prostate, gynecologic, and metastatic cancers, while integrating artificial intelligence (AI) into clinical decision-making. His research spans oncology, neurodegenerative diseases, and sleep medicine. Education: MD (University of Alberta), BSc in Physics (Western University) Training: Radiation Oncology Residency (UCLA), Brachytherapy Fellowship (USC) Dr. Lim's research focuses on: AI for personalized medical predictions using genomics and radiology data Brachytherapy optimization for cancer treatment Sleep disorders and their links to cognitive decline (Alzheimer's, Parkinson's) Medical imaging analysis (radiomics, white matter hyperintensities) Recent publications highlight his work on machine learning in prostate cancer diagnosis , GRID collimator dosimetry , and sleep fragmentation in neurodegenerative diseases . He has received awards from the University of Alberta and St. Francis Xavier University.

Mara Matherمشاهده پروفایل

استاد

• Aging
• Neuroscience
• Alzheimer's Disease
• +۳ مورد دیگر

Mara Mather is a Professor of Gerontology, Psychology, and Biomedical Engineering at the Leonard Davis School of Gerontology, University of Southern California. She leads the Emotion & Cognition Lab, focusing on the autonomic nervous system's role in aging and Alzheimer’s disease. Her research explores how locus coeruleus dysfunction impacts cognition and how interventions like heart rate variability biofeedback may improve brain health. Education: PhD in Neuroscience from Princeton University (2000), AB from Stanford University (1994). Research interests include the autonomic nervous system’s influence on brain aging, Alzheimer’s pathology, and emotion-cognition interactions. Key projects investigate locus coeruleus MRI contrast, heart rate variability interventions, and neuroimaging biomarkers of cognitive decline. Awards include the 2024 USC Mentoring Award. Her lab collaborates on studies linking autonomic function to late-life memory and has pioneered interventions targeting cerebrovascular health. The lab is located in GER 341, with active projects on aging, Alzheimer’s, and biofeedback technologies.

Janos Peti Peterdiمشاهده پروفایل

استاد

• Renal Physiology
• Kidney Pathophysiology
• Cardiovascular Regulation
• +۷ مورد دیگر

Dr. Janos Peti-Peterdi is a Professor of Physiology & Biophysics and Medicine at the University of Southern California's Keck School of Medicine, where he has been tenured since 2007. As Director of the NIH-funded Multi-Photon Microscopy Core, he pioneered intravital multiphoton microscopy techniques to study kidney (patho)physiology, focusing on mechanisms of body fluid/electrolyte regulation, blood pressure control, and chronic kidney disease. Department of Physiology and Biophysics Department of Medicine Director, ZNI Multiphoton Core Facility Acting Vice Chair of Physiology & Neuroscience His research explores: Kidney injury and regeneration mechanisms using serial multiphoton imaging Macula densa cell signaling in hypertension and diabetes Endothelial glycocalyx regulation of glomerular filtration Renin secretion dynamics and therapeutic targeting Renal stem cell fate in tissue repair Development of regenerative therapies for kidney diseases Recent publications reveal trends in: Podocyte glycocalyx alterations in diabetes Neuronally differentiated endothelial cells in vascular regulation Novel imaging techniques for intrarenal ion dynamics mTORC1 signaling in aging-related kidney function Therapeutic targeting of macula densa cells Kidney-brain crosstalk via CCN1 Scientific honors include: Carl W. Gottschalk Research Scholar Award (ASN) Young Investigator Award (APS Renal Section) American Heart Association Established Investigator Dr. Peti-Peterdi serves as Associate Editor for American Journal of Physiology Renal Physiology and directs a core facility training over 30 international researchers in kidney imaging techniques.

Ruslan Rustمشاهده پروفایل

استادیار

• Stem Cell Therapy
• Neurodegenerative Disorders
• Blood-Brain Barrier (BBB)
• +۳ مورد دیگر

Ruslan Rust is an Assistant Professor of Research in Physiology and Neuroscience at the Zilkha Neurogenetic Institute, part of the Keck School of Medicine at the University of Southern California. His research focuses on advancing cell therapies for neurodegenerative diseases like stroke and Alzheimer’s, leveraging induced pluripotent stem cell (iPSC)-derived cells such as pericytes and neural stem cells. He employs cutting-edge techniques including gene editing, single-cell omics, and deep learning-based behavioral analysis to address challenges in graft delivery, immunocompatibility, and BBB permeability. Recent work emphasizes BBB dynamics, molecular profiling of stroke repair phases, and optimizing therapeutic strategies for clinical translation. Education and affiliations include doctoral training and postdoctoral experience, though specific details are not listed here. He collaborates with institutions like ETH Zurich and the University of Zurich (UZH), as noted on his professional profiles. His work bridges basic science with clinical applications, aiming to accelerate therapies toward human trials. Publications highlight advancements in stroke biomarkers, neurovascular unit dysfunction, and stem cell transplantation efficacy. Key themes include BBB modulation, neuroregeneration mechanisms, and the development of standardized tools for preclinical stroke research. His contributions are disseminated through high-impact journals like Advanced Science , Brain , and Stem Cell Reports .

• Neurology
• Pediatric Neurology
• Neuroimmunology
• +۳ مورد دیگر

Jonathan Santoro is an Associate Professor of Clinical Neurology and Pediatrics at the University of Southern California. His research focuses on neuroinflammation, autoimmune disorders, and Down syndrome, with a particular emphasis on Down Syndrome Regression Disorder (DSRD). He has contributed to advancements in immunotherapy, neuroimaging biomarkers, and clinical management strategies for neuroimmunological conditions. Key areas of expertise include pediatric neurology, autoimmune encephalitis, and the intersection of genetics with neurological disorders. His recent work highlights the role of immunotherapy in treating DSRD and explores the genetic and immunological underpinnings of neurodegenerative and neuroinflammatory diseases. Dr. Santoro has published extensively on topics such as graft-versus-host disease, mitochondrial disorders, and neurovascular complications. He has also been recognized with the Pediatric Neurology Trainee Award , reflecting his contributions to education and clinical practice.