جست‌وجوی استاد و پژوهشگر

Hassane Amlalمشاهده پروفایل

عضو هیئت علمی

• Renal Physiology
• Ion Transport
• Acid-Base Balance
• +۴ مورد دیگر

Hassane Amlal is a Research Associate Professor of Medicine in the Division of Nephrology and Hypertension at the University of Cincinnati College of Medicine. His career spans over 25 years in renal physiology research, focusing on molecular regulation of ion transporters and acid-base homeostasis. He earned a Doctoral Degree in Renal Physiology from University Pierre et Marie Curie (Paris 6) and completed postdoctoral training at the University of Cincinnati. University Cadi Ayyad (1989): Bachelor's in Animal Biology University of Nancy I (1989): Certificate in Physiology University Pierre et Marie Curie (1990): Master's in Renal Physiology University Pierre et Marie Curie (1994): Doctoral Degree in Renal Physiology Dr. Amlal's research explores renal epithelial salt, water, and acid-base transporters in health and disease states. His work has elucidated mechanisms of potassium depletion, estrogen regulation of phosphate transport, fructose-induced hypertension, and compensatory responses in genetic transporter models. His publications (15+ peer-reviewed articles) reveal expertise in NBC-1/NHE-3 transporter interactions, pendrin function, and estrogen receptor-mediated kidney regulation. Notable findings include characterizing acidosis-induced AQP2 upregulation and identifying Slc26a6's role in fructose hypertension. Government Scholarships (Morocco, 1984-1994) INSERM Scholarship (France, 1991-1994) 2nd Prize at UC Fellows' Grand Rounds (1997) He serves on editorial/reviewer boards for journals like JASN and Kidney International, and holds leadership roles in academic committees. Current funding includes DCI Bridge Funding (PI, $150k) and NIDA grants for anti-cocaine antibody development.

Brian M Forsterمشاهده پروفایل

مدرس پزشکی

• Microbiology Education
• Science Pedagogy for Non-Science Majors
• Environmental Science Education
• +۳ مورد دیگر

Dr. Brian M. Forster is the GEP Science Lab Coordinator and Chemical Hygiene Officer at Saint Joseph's University's Department of Biology. With a PhD in Microbiology from Cornell University (2011) and a BS in Biological Sciences (Cell/Molecular) from SUNY Binghamton (2006), he specializes in pedagogical innovations for non-science majors through laboratory-based courses in microbiology, environmental science, and quantitative skills development. Institutional Affiliation: Saint Joseph's University, College of Arts and Sciences Education: PhD Microbiology (Cornell), BS Biological Sciences (SUNY) His research interests focus on science education for non-majors, including: Microbiology education pedagogy Environmental science laboratory design Quantitative skill integration Interactive educational technology Science outreach program development Curriculum standardization for allied health Recent publications highlight his work on climate change education (2024), interactive GMO simulations (2023), microscopy skill development (2023), and rain garden pedagogy (2021). These works span environmental science education , microbiology laboratory innovation , and quantitative reasoning frameworks. Scientific recognitions include: 2017 Faculty Merit Award for Teaching 2016 Exemplary Contribution to Journal Curriculum Section 2014 #topprofsju Award He actively participates in science outreach through the Eastern Pennsylvania Branch of the American Society for Microbiology (co-chair of education committee) and Delaware Valley Science Fairs (board member). His laboratory facilities in Connelly Hall feature state-of-the-art AV systems, Leica/Olympus microscopes, and computer-assisted data analysis tools for general education science courses.

Håkan Axelsonمشاهده پروفایل

استاد

• Cancer and Oncology
• Basic Cancer Research
• Kidney Cancer Diagnosis
• +۳ مورد دیگر

Håkan Axelson is a Professor at Lund University's Division of Translational Cancer Research and a Principal Investigator at the Lund University Cancer Centre (LUCC). His work focuses on kidney cancer, particularly clear cell renal cell carcinoma (ccRCC), using hypoxia and VHL gene loss as model systems. Research areas: Tumor hypoxia, Notch signaling, SLC6A3 biomarker Key contributions: Characterization of ccRCC subtypes, novel model systems for kidney cancer Research Trends: His recent articles emphasize hypoxia pathways, biomarker discovery, and signaling crosstalk in kidney and brain cancers. Collaboration Network: Active in organizing uro-oncology conferences and leading interdisciplinary projects on cancer microenvironment and liquid biopsy development.

• Nephrology
• Molecular Biology
• Physiology
• +۳ مورد دیگر

David Pearce, MD, is a Professor of Medicine and Cellular & Molecular Pharmacology at the University of California, San Francisco (UCSF). He serves as Chief of Nephrology at San Francisco General Hospital, a core teaching hospital affiliated with UCSF. His expertise lies in renal physiology and ion transport mechanisms, with a focus on hormone-regulated pathways in kidney tubules. Dr. Pearce completed his MD at the University of Chicago Pritzker School of Medicine, followed by residency in Internal Medicine at Harbor-UCLA Medical Center and a Nephrology fellowship at UCSF. His research investigates the molecular mechanisms underlying sodium and potassium homeostasis, particularly the role of SGK1 and mTORC2 signaling pathways. Key contributions include identifying multiprotein complexes regulating ion transport and developing preclinical therapies for hypertension and metabolic syndrome. His work is funded by NIH R01 grants and Foundation awards. Recent studies highlight mTORC2's role in coordinating renal glucose and potassium regulation, with implications for hypertension treatment. Dr. Pearce's lab also explores aldosterone-independent potassium regulation and the therapeutic potential of SGK1 inhibitors. His collaborative projects integrate metabolic imaging and genetic models to advance understanding of renal and metabolic disorders.

• Regenerative Medicine
• Stem Cell Research
• Pediatric Nephrology
• +۵ مورد دیگر

Sargis Sedrakyan is an Assistant Professor in the Department of Research Urology at the University of Southern California. His work focuses on regenerative medicine, stem cell biology, and pediatric nephrology. Current research areas: Extracellular Vesicles in Kidney Development, Glomerular Endothelial Dysfunction, and Mitochondrial Transplantation in Renal Injury His publications highlight expertise in spatial transcriptomics, Alport syndrome, and bioengineering of renal tissue. Collaborations include researchers like Andrew McMahon and Stefano Da Sacco. Key contributions: Development of non-invasive MRI tracking for extracellular vesicles, characterization of Wilms tumor cancer stem cells, and decellularized renal matrix models

• Microbiology
• Antimicrobial Resistance
• Bacterial Metabolism
• +۳ مورد دیگر

Chris Barlow is a Research Fellow at Monash University's Proteomics Platform. His work focuses on bacterial metabolism, antimicrobial resistance mechanisms, and pathogen survival strategies. He contributes to projects investigating bacterial persistence, such as understanding how bacteria survive nutrient deprivation and resist antimicrobial treatments. His research spans microbiology, proteomics, and infectious disease dynamics. Affiliations: Proteomics Platform, Monash University Key Projects: Preventing a nephron deficit in premature offspring CSIRO AMR & Nutrition Pilot Clinical Study Flaviviruses structural vaccinology Research Interests: Barlow’s studies explore metabolic processes in bacteria, particularly how pathogens adapt to environmental stresses. His work includes analyzing endolysin mechanisms in Clostridioides difficile , arginine catabolism in Acinetobacter baumannii , and host-pathogen interactions in Chlamydia trachomatis . He employs proteomics and metabolomics approaches to uncover novel therapeutic targets. Publications: His recent articles highlight advancements in understanding bacterial survival strategies, including toxin regulation, antibiotic resistance pathways, and metabolic adaptations under hypoxic conditions. These findings contribute to developing new antimicrobial therapies and diagnostic tools.

John Bertramمشاهده پروفایل

استاد

• Kidney Disease
• Nephrology
• Developmental Biology
• +۶ مورد دیگر

John Bertram is a Professor in the Department of Anatomy & Developmental Biology at Monash University, affiliated with the Monash Biomedicine Discovery Institute. His expertise focuses on kidney structure and development, particularly nephron and glomeruli counts, which are critical for understanding chronic diseases. He pioneered quantitative kidney pathology, analyzing thousands of kidney samples globally to establish baseline nephron/glomeruli numbers and their variability. His work highlights environmental and genetic influences on kidney development, with implications for hypertension, kidney disease, and public health. Key projects include investigating low nephron endowment's role in chronic diseases, podocyte biology, and using MRI for 3D kidney analysis. He collaborates internationally, including NIH-funded research on renal regeneration. Grants include NHMRC support for podocyte-stem cell studies. His research contributes to UN SDGs addressing health and well-being. Research interests span kidney development, developmental origins of disease, and translational therapies. Recent work explores 3D imaging, podocyte depletion, and obesity-related glomerulopathy outcomes. Collaborations span institutions like the Australian Regenerative Medicine Institute and Howard Florey Institute.

Luise Cullen-McEwenمشاهده پروفایل

پژوهشگر ارشد

• Kidney Development
• Embryogenesis
• Nephron Development
• +۳ مورد دیگر

Dr. Luise Cullen-McEwen is a Research Fellow in the Department of Anatomy and Developmental Biology at Monash University, within the School of Biomedical Sciences. Her research focuses on kidney development, particularly the regulation of branching morphogenesis and nephron number during embryogenesis. She holds a PhD from Monash University (2002) and has extensive expertise in techniques like immunofluorescence, histology, and unbiased stereology. Her work includes projects funded by the Australian Kidney Foundation and NHMRC, investigating maternal diabetes effects on kidney development and chronic kidney disease progression. Key collaborations involve Jikei University Hospital and researchers in Japan. She has led projects addressing nephron deficits in premature offspring and the impact of maternal nutrition on kidney structure. Research interests span GDNF signaling in kidney development, podocyte adaptation, and the role of maternal conditions (e.g., diabetes, protein restriction) in programming renal deficits. Over 70 publications highlight her contributions to nephrology and developmental biology.

Ian Smythمشاهده پروفایل

استاد

• Developmental Biology
• Kidney Development
• Skin Biology
• +۴ مورد دیگر

Dr. Ian Smyth is a Professor of Anatomy & Developmental Biology at Monash University's Monash Biomedicine Discovery Institute in Melbourne, Australia. He holds a PhD from the University of Queensland (1999) and has conducted postdoctoral research at the MRC Human Genetics Unit (Edinburgh) and Baylor College of Medicine (Houston), followed by roles at Cancer Research UK and as an NHMRC RD Wright Fellow. His research focuses on developmental mechanisms in mouse embryology, particularly skin and kidney development, with an emphasis on human disease models. He employs mouse genetics and advanced imaging techniques to study branching morphogenesis and congenital disorders. Smyth leads multiple research projects on polycystic kidney disease (PKD), including therapeutic development and molecular pathways. He actively supervises PhD students and collaborates internationally. Notable press coverage includes breakthroughs in PKD treatment and kidney development imaging. Research Interests: Epithelial differentiation in embryonic development Mouse genetic models of human kidney/skin diseases Imaging analysis of branching morphogenesis Polycystic kidney disease mechanisms Recent Research Trends: His articles (2020-2025) highlight advancements in PKD treatment via kinase inhibition (Aurora kinase A), inflammation modulation (IL-37), and regenerative approaches (cardiac organoids). Collaborations span kidney genomics (KidGen project) and interdisciplinary teams addressing congenital disorders and aging mechanisms. Grants/Projects: Active grants include PKD therapeutic development with Targeted Protein Degraders (TPDs) and ciliary fission studies. He leads projects funded by PKD Foundation Australia and NHMRC. Over 38 research projects documented, many as Principal Investigator. Labs/Teams: Coordinates a lab focusing on kidney/epidermal development using genetic, molecular, and computational approaches. Collaborates with institutions globally in functional genomics and clinical translation.

• Kidney Organoid Development
• Pluripotent Stem Cell Research
• Bioengineering
• +۳ مورد دیگر

Elena Garreta Bahima is a prominent researcher affiliated with the Pluripotency for Organ Regeneration group at the Institut de Bioenginyeria de Catalunya (IBEC) . Her work focuses on advancing bioengineering approaches to generate kidney organoids from human pluripotent stem cells, with particular emphasis on kidney regeneration, disease modeling, and translational medicine. She leads interdisciplinary projects integrating stem cell biology, material science, and virology to address challenges in organoid maturation and disease mechanisms. Her research interests include the development of bioengineered kidney organoids to study renal development and pathologies such as diabetic nephropathy, as well as the application of CRISPR technologies for genetic editing in organoid systems. She has pioneered studies on SARS-CoV-2 infection mechanisms using kidney organoids, revealing insights into ACE2 regulation and viral susceptibility in diabetic conditions. Key contributions include optimizing extracellular environments for organoid maturation, leveraging natural hydrogels for vascularization, and advancing mechanobiology approaches to study nephron morphogenesis. Her work bridges fundamental science and clinical applications, with a vision to translate organoid models into therapies for kidney diseases. Collaborations extend to institutions like the University of Barcelona, Hospital Clínic de Barcelona, and international groups, emphasizing multi-organoid systems and bioengineering innovation. Her research has been featured in high-impact journals such as Cell Metabolism , Nature Materials , and Advanced Materials .

Satoshi Shimadaمشاهده پروفایل

مدرس

• Renal Physiology
• Hypertension
• Kidney Disease Pathophysiology
• +۳ مورد دیگر

Satoshi Shimada, PhD, is an Instructor in the Department of Physiology at the Medical College of Wisconsin. His research focuses on renal physiology, hypertension mechanisms, and kidney metabolism, with a particular emphasis on cardiorenal syndrome and salt-sensitive hypertension. He completed his MD and PhD at Tohoku University in Japan, followed by residency training and postdoctoral work under Dr. Allen Cowley. His technical expertise includes chronic renal hemodynamic measurements, surgical techniques in rodents, and metabolomic analyses. Education: PhD, Graduate School of Medicine, Tohoku University (2019) MD, School of Medicine, Tohoku University (2013) Residency in Internal Medicine, South Miyagi Medical Center (2012–2015) Postdoctoral Research Fellow, Medical College of Wisconsin (2018–present) Research Interests: Dr. Shimada investigates mechanisms underlying renal fibrosis, hypertension-induced kidney damage, and metabolic adaptations to high-salt diets. His work combines advanced surgical techniques (e.g., chronic renal blood flow monitoring) and molecular approaches to study pathways like mTOR signaling, oxidative stress, and mitochondrial dysfunction. Recent findings include the role of NADPH oxidase 4 in renal oxygen consumption and the impact of mTORC2 inhibition on sodium transport. Article Trends: His publications emphasize high-salt diet effects on renal metabolism, mitochondrial dysfunction in Dahl salt-sensitive rats, and the interplay between renal hemodynamics and inflammation. Key themes include metabolic shifts in proximal tubules, oxidative stress pathways, and mechanistic insights into salt-sensitive hypertension. Awards: 2021 Renal Section Research Recognition Award 2019 AHA/ASH New Investigator Award 2017 Japanese Society of Pathophysiology Award Labs/Teams: He conducts research in Dr. Allen Cowley’s renowned renal physiology laboratory, focusing on developing novel methods for studying kidney function in conscious animals to minimize anesthesia-induced artifacts.

• Nephrology
• Hypertension
• Diabetic Nephropathy
• +۲ مورد دیگر

Susan Bailey Gurley, MD, PhD is the Kenneth T. Norris, Jr. Chair and Chair of the Department of Medicine at the Keck School of Medicine, University of Southern California . She is a Physician Scientist specializing in nephrology with over 20 years of expertise in diabetic nephropathy , hypertension , and the renin-angiotensin system (RAS) . Her leadership roles include directing the Division of Nephrology & Hypertension at Oregon Health & Science University (OHSU) and serving as interim chair at OHSU from 2021-2023. Education: PhD in Biophysical Chemistry , University of Mississippi MD, Washington University School of Medicine in St. Louis, MO Residency in Internal Medicine and Fellowship in Nephrology , Duke University School of Medicine Research Interests: Dr. Gurley's work focuses on mouse models of diabetic nephropathy and hypertension , with a particular emphasis on ACE2 and angiotensin II receptors in blood pressure and kidney injury. Her studies span genomic and metabolomics analyses , conditional gene targeting , and cardiovascular-renal interactions . Her recent publications highlight ACE2 deficiency in acute kidney injury, sex differences in RAS , and translational implications of her work for hypertension and diabetic complications . Scientific Recognition: She holds the Kenneth T. Norris, Jr. Chair in Medicine , a prestigious academic appointment reflecting her leadership in clinical and research nephrology . Her publications in high-impact journals like Hypertension , JASN , and Kidney International demonstrate her sustained contributions to RAS biology and kidney disease mechanisms . Leadership & Practice: As Chair, she oversees the Department of Medicine at Keck, emphasizing academic development and biomedical research . She also practices clinically at Keck Hospital of USC and USC Norris Cancer Hospital , with expertise in internal medicine and transplant nephrology . Her work bridges basic science , translational research , and clinical leadership in kidney disease and hypertension .

• Neonatology
• Pediatric Nephrology
• Developmental Origins of Health and Disease
• +۳ مورد دیگر

Yogavijayan Kandasamy is a researcher affiliated with James Cook University (JCU), focusing on neonatal and maternal health. His work spans epidemiology, pediatric nephrology, and developmental origins of health and disease. He has collaborated extensively on studies addressing stillbirth risks in Indigenous populations, kidney development in preterm infants, and the impact of maternal smoking on birth outcomes. Key research interests include neonatal jaundice management, biomarker discovery for kidney injury, and the application of artificial intelligence in clinical decision-making. His systematic reviews explore topics like caffeine’s role in neonatal kidney protection and the feasibility of home phototherapy. Recent publications highlight collaborations with colleagues in obstetrics, nephrology, and public health. Though no formal awards are listed, his contributions to understanding fetal and neonatal kidney development through ultrasonography and biomarkers are notable.

• Rare and Undiagnosed Diseases
• Genetic Technologies (CRISPR-based approaches)
• Clinical Diagnostics Development
• +۵ مورد دیگر

Caroline Hendry is a Researcher and Scientific Director in the Genetics Department at Yale School of Medicine. She serves as Advisor to the Chair of Genetics and Director of the Office for Strategic Research Development, focusing on advancing rare disease research, population health screening, and gene-based therapies. Her work emphasizes cross-functional research collaboration and operational efficiency in both basic and clinical research domains. Education: BSc (Honors) in Genetics from the University of Queensland (2006), PhD in Developmental Genetics from the University of Queensland's Institute for Molecular Bioscience (2010), and postdoctoral training in molecular reprogramming at Mount Sinai School of Medicine (2012). Currently completing an MBA at Yale School of Management, specializing in healthcare leadership. Research Interests: Her work centers on rare disease discovery, innovative genetic technologies (including CRISPR applications), AI-driven clinical diagnostics, and value-based healthcare models. She actively develops tools for population health screening and explores AI's role in optimizing clinical evaluation processes. Professional Contributions: Co-Investigator on major NIH grants in clinical-translational research. Leads strategic initiatives in rare disease research and has published extensively on topics ranging from stem cell migration to epigenetic reprogramming mechanisms. Active in academic leadership, advocating for complementary scientific director roles to enhance institutional research capacity. Grants & Administration: Oversees strategic research development at Yale Genetics, including portfolio planning and operational systems improvement. Engaged in initiatives to advance gene therapy and IND-enabling research for cell-based treatments.

Catherine Meyer-Schwesingerمشاهده پروفایل

استاد

• Nephrology
• Podocyte biology
• Autoimmune glomerulonephritis
• +۵ مورد دیگر

Professor Catherine Meyer-Schwesinger is Director of the Institute of Cellular and Integrative Physiology within the Center for Experimental Medicine at the University Medical Center Hamburg-Eppendorf (UKE). She is a distinguished nephrologist with expertise in podocyte biology, kidney diseases, and autoimmune glomerulonephritis. Her research has significantly advanced our understanding of the molecular mechanisms underlying various kidney pathologies. Dr. Meyer-Schwesinger's primary research interests include: Podocyte biology and injury mechanisms Membranous nephropathy and autoimmune kidney diseases The role of the ubiquitin-proteasome system in kidney physiology Complement system activation in kidney disease Mechanisms of proteinuria and glomerular filtration Her extensive publication record demonstrates a consistent focus on the cellular and molecular mechanisms of kidney disease. Recent work has particularly emphasized the role of podocytes in kidney function and disease, with investigations into how autoantibodies, complement activation, and cellular proteostasis contribute to glomerular damage. Her research employs advanced techniques including single-cell transcriptomics, multiplex imaging, and sophisticated animal models to unravel complex disease mechanisms. Among her notable scientific contributions are discoveries related to: The pathogenic role of autoantibodies in podocytopathies Mechanisms of complement activation in membranous nephropathy The function of the ubiquitin-proteasome system in podocyte health Novel insights into anion exchangers and kidney physiology Immune cell contributions to kidney inflammation and damage Dr. Meyer-Schwesinger has established herself as a leader in nephrology research, with her work frequently published in high-impact journals including Nature, Cell, Journal of the American Society of Nephrology, and Kidney International. Her research program bridges basic science with clinical applications, aiming to develop new diagnostic and therapeutic approaches for kidney diseases.