جستجوی استاد راهنمای دانشگاهی

• Endocrinology
• Fetal Development
• Placental Function
• +۱۰ مورد دیگر

Sean W. Limesand is a Professor of Endocrinology in the School of Animal and Comparative Biomedical Sciences at the University of Arizona. He holds joint appointments with the Department of Obstetrics and Gynecology and the BIO5 Institute. Dr. Limesand serves as Director of the Agricultural Research Center and holds the Hislop-Ede Endowed Chair. He is also Chair of the University Radiation Safety Committee. Education: Ph.D. in Molecular Endocrinology, Colorado State University M.S. in Molecular Endocrinology, Colorado State University Bachelor’s in Biotechnology, North Dakota State University Dr. Limesand's research focuses on fetal endocrinology, placental function, and the developmental origins of metabolic diseases such as diabetes and intrauterine growth restriction (IUGR). He employs an integrative ovine model to study pancreatic β-cell function, insulin secretion, and metabolic adaptation at the whole-animal, organ, cellular, and molecular levels. His work extends to insulin action in skeletal muscle and developmental programming of adipose tissue. The recent publications highlight a strong trend in understanding metabolic dysregulation in growth-restricted fetuses, with emphasis on insulin signaling, mitochondrial dysfunction, epigenetic regulation, and sex-specific programming. His studies frequently involve transcriptomic, proteomic, and metabolic flux analyses in ovine and rodent models. Scientific Awards: Research Faculty of the Year, CALS, Fall 2015 Dr. Limesand has been continuously funded by the National Institutes of Health for over 23 years and has also received grants from the Bill & Melinda Gates Foundation, USDA, and JDRF. He mentors graduate students and teaches courses in endocrinology, physiology, and reproduction. He has held leadership roles in the Perinatal Research Society and the Perinatal Biology Symposium. His lab investigates long-term consequences of fetal metabolic stress and explores prenatal interventions to mitigate developmental programming of disease. Labs and Research Teams: His research is conducted through a multidisciplinary team utilizing advanced physiological, molecular, and imaging techniques, primarily based at the University of Arizona’s Agricultural Research Center and affiliated laboratories.

• Diabetes in Pregnancy
• Gestational Diabetes
• Metabolic Disease in Pregnancy
• +۷ مورد دیگر

Dr. Arianne Sweeting is a Senior Lecturer in Endocrinology at the University of Sydney's Faculty of Medicine and Health and serves as a Staff Specialist Endocrinologist at Royal Prince Alfred Hospital, where she leads the Maternal Metabolic Health service. She is also a member of the Charles Perkins Centre and holds significant leadership roles in diabetes in pregnancy research and clinical practice. Dr. Sweeting earned her MBBS (Hons), BSc in Neuroscience, Graduate Diploma in Public Health Law from Sydney Law School, and PhD from the University of Sydney's Faculty of Medicine and Health. She became a Fellow of the Royal Australasian College of Physicians in 2015 after receiving NHMRC postgraduate and Albert S McKern obstetric research scholarships for her PhD work on risk management in Gestational Diabetes. Her research focuses on metabolic disease in pregnancy, including diabetes, obesity, bariatric surgery, and eating disorders, with particular emphasis on precision medicine diagnostics, nutrition interventions, and risk management to improve health outcomes for women and their babies. She has pioneered work on early gestational diabetes, establishing and leading the Metabolic Health in Pregnancy service. Her recent publications (2024-2025) demonstrate a strong focus on precision medicine applications in gestational diabetes, with numerous high-impact publications in journals like The Lancet, Diabetes Care, and Communications Medicine. Her work spans epidemiology, pathophysiology, clinical trials (particularly the TOBOGM study), and systematic reviews addressing critical gaps in diabetes management during pregnancy. Australian Diabetes Society Skip Martin Fellow (2022) Sydney Medical School Dean's Publication Prize (2016) International Diabetes Federation World Diabetes Congress Travel Grant (2015) NHMRC Postgraduate Scholarship Albert S McKern Obstetric Research Scholarship Dr. Sweeting leads multiple research projects including the TOBOGM international multicentre trial on early detection of gestational diabetes, PREBABE preconception weight loss trial, and systematic reviews on precision medicine diagnostics. She has secured significant grant funding including the Australian Diabetes Society Early Career Fellowship and MRFF funding for the PreBabe study. Her leadership extends to national and international organizations, including past presidency of the Australasian Diabetes in Pregnancy Society (2020-2022) and membership on the International Association for the Diabetes and Pregnancy Study Groups Council.

• Diabetes Research
• Pancreatic Islet Biology
• Metabolic Diseases
• +۳ مورد دیگر

Dr. Estela Lorza Gil is a Senior Scientist and Group Leader at the Helmholtz Diabetes Center, University of Tübingen, Medical Faculty. Her research focuses on pancreatic islet biology, metabolic diseases, and inter-organ communication in diabetes pathophysiology. Education: PhD in Molecular and Functional Biology (2006-2011) B.S. in Biological Sciences Research Interests: Investigating islet-adipose tissue interactions Developing human organoid models for diabetes research Elucidating mechanisms of beta cell dysfunction Studying free fatty acid receptor signaling in islets Analyzing metabolic-inflammatory crosstalk in T2D Characterizing pancreatic fat cell activity Publications: Recent work explores incretin-responsive organoids, inter-organ communication in diabetes, and receptor signaling pathways in islet function. Her research spans molecular metabolism, beta cell physiology, and translational diabetes models. Awards: DZD Award (2019) Appointments: 2022: Senior Scientist, Helmholtz Diabetes Center 2017-2022: Postdoctoral Researcher

• Congenital Heart Disease
• Pediatric Cardiology
• Xenotransplantation
• +۴ مورد دیگر

Luz Padilla is an Associate Professor in the Department of Epidemiology at the University of Alabama at Birmingham (UAB) School of Public Health. She holds a secondary appointment as Assistant Professor in UAB School of Medicine's Department of Surgery, Cardiovascular/Thoracic Division, and serves as Director of Surgical Research for the Joseph S. Bruno Pediatric Heart Center of Alabama. Dr. Padilla also functions as Vice-Chair and board member on the UAB Institutional Review Board. Her research focuses on Congenital Heart Disease , Pediatric Cardiology , and Xenotransplantation , with particular interest in ethical frameworks for pediatric clinical trials, surgical outcomes evaluation, and public health implications of xenotransplantation. Over the past decade, her publications have explored xenotransplantation acceptance among healthcare professionals, genetic factors in transplant outcomes, and global health disparities in transplant medicine. Key educational contributions include her role as course master for PUH201 - Introduction to Public Health and EPI699 - Project Research . She has served on graduate thesis committees for students including Michelle Kung and Isabel Cuellar Acker. Current grants examine genetically engineered pig organ transplantation in baboons and pediatric cancer research training programs. Scientific Awards Outstanding Masters Student of the Year (University of Alabama at Birmingham, 2016)

Mary Kearns-Jonkerمشاهده پروفایل

دانشیار

• Regenerative Medicine
• Stem Cell Biology
• Xenotransplantation
• +۷ مورد دیگر

Mary Kearns-Jonker is an Associate Professor in the Department of Pathology and Human Anatomy at Loma Linda University School of Medicine and serves as Co-Program Director of the Cancer, Developmental and Regenerative Biology PhD program. Her research is centered on regenerative medicine, with a focus on stem cell biology, xenotransplantation, and the impact of microgravity on cardiovascular progenitor cells. Her research interests span regenerative medicine , stem cell biology , cardiovascular development , and space biomedicine . She investigates how neonatal cardiovascular progenitor cells can be harnessed for cardiac repair, including mechanisms involving YAP1 signaling, extracellular vesicles, and the effects of hypoxia and microgravity. Her lab has pioneered studies on stem cell behavior in space, using the International Space Station to explore how microgravity alters gene expression and functional properties of progenitor cells, with implications for both Earth-based and space-based regenerative therapies. The recent publication trends highlight a strong focus on cardiac regeneration , microgravity effects , biomaterial scaffolds , and transcriptomic analysis . Her work bridges molecular biology, tissue engineering, and translational medicine, with increasing emphasis on space biomanufacturing and biotechnology. Efficient Generation of Integration-Free iPS Cells from Human Adult Peripheral Blood Using BCL-XL Together With Yamanaka Factors (2013) Gene therapy to inhibit xenoantibody production using lentiviral vectors in non-human primates (2007) Dr. Kearns-Jonker has led significant research initiatives, including a project on generating integration-free iPS cells and studies on xenotransplantation immunology. Her work has been supported by research grants related to gene therapy, stem cell transplantation, and spaceflight experiments. She mentors students and researchers in the Cancer, Developmental and Regenerative Biology program and contributes to advancing regenerative therapies for heart failure and organ repair. Her research team actively explores innovative solutions for end-stage organ failure, combining xenotransplantation strategies with stem cell-based repair. Current efforts include biomanufacturing in low Earth orbit and understanding how spaceflight alters stem cell regenerative potential, positioning her at the forefront of space biomedical research.

• Obstetrics
• Gynecology
• Placental Research
• +۷ مورد دیگر

Professor Manu Vatish holds the position of Professor of Obstetrics and Consultant Obstetrician at the University of Oxford. He serves as Principal Investigator, Research Group Leader, Grant Holding Senior Scientist, and Clinical Consultant in Obstetrics. Additional leadership roles include NIHR CRN Clinical Director for Thames Valley & South Midlands, RCOG College Tutor for Oxford, and Academic Training Programme Director for OUCAGS. He is also an Associate Group Leader at the Wellcome Centre for Human Genetics. His educational background includes preclinical medicine at Keble College, Oxford, followed by a DPhil at Brasenose College, Oxford under Dr. Richard Boyd, and clinical training at Cambridge (Queens' College). Specialist training in obstetrics & gynaecology on the Oxford training rotation was followed by clinical and senior lectureships at Warwick, with Fulbright and Churchill Fellowships in New York and Yale preceding his return to Oxford in 2013. Professor Vatish's research focuses on translational obstetrics, particularly pregnancy complications like preeclampsia and gestational diabetes. His work centers on placental biology with specific streams in extracellular vesicles, mitochondrial therapy, circulating angiogenic biomarkers, computerized CTG systems, genetic screening of newborns, and vaccines in pregnancy. His research spans from basic molecular mechanisms to clinical applications of diagnostic tools in obstetric practice. His recent publications (2024-2025) demonstrate strong focus on placental biology, preeclampsia biomarkers, and pregnancy-related complications, with significant contributions to understanding molecular mechanisms and developing clinical applications. His notable awards include: 2008 Fulbright Distinguished Scholar Award 2011 Churchill Fellowship 2019 HSJ Partnership Award 2019 UNIVANTS of Healthcare Excellence Professor Vatish currently supervises numerous DPhil students and postdoctoral researchers including Toluwalase Awoyemi (Rhodes Scholar), William Cooke (Wellcome Trust), Shuhan Jiang (CNSF), and Gabriel Jones (Clarendon Scholar). His research is supported by multiple grants including those from Silence Therapeutics, Roche Diagnostics, MRC, Janssen Pharmaceuticals, and the Helmsley Trust through GPADD. He leads a vibrant research group focused on translational obstetrics with specific research streams on pre-eclampsia, mitochondria, extracellular vesicles, and biomarker development. The group collaborates with industrial partners like Sysmex/JVCKenwood and LUCA Science to develop diagnostic tools and therapeutic approaches for pregnancy complications.

Sean Limesandمشاهده پروفایل

استاد

• Fetal Development
• Endocrinology
• Animal Physiology
• +۳ مورد دیگر

Sean Limesand, PhD is a Professor at the University of Arizona's School of Animal Sciences & Comparative Biomedical Sciences. His research focuses on fetal development, endocrine adaptations, and metabolic programming in animal models, particularly sheep and goats. Key areas include fetal growth restriction (FGR), placental insufficiency, and the long-term impacts of in utero stressors like hypoxia, heat, and maternal infections. His work integrates molecular biology (e.g., transcriptomics), cellular physiology (e.g., β-cell function), and whole-animal studies. Notable contributions include identifying dysregulated pathways in growth-restricted fetal tissues, characterizing mitochondrial adaptations in FGR, and exploring therapeutic interventions (e.g., oxygen/glucose therapy in ovine models). Research also addresses environmental challenges like maternal heat stress and its effects on lactation/placental function, as well as SARS-CoV-2's impact on maternal-neonatal outcomes. His studies often involve interdisciplinary approaches, combining omics technologies with physiological measurements to understand developmental origins of health and disease. Current studies investigate single-cell transcriptomics of SS-cells in FGR, epigenetic modifications in thermotolerant ewes, and molecular mechanisms linking fetal programming to adult metabolic disorders. These efforts aim to translate findings into clinical strategies for managing growth-restricted infants and improving livestock resilience.

Arupa Gangulyمشاهده پروفایل

استاد

• Ocular tumor genetics
• Retinoblastoma molecular mechanisms
• Uveal melanoma genomics
• +۴ مورد دیگر

Arupa Ganguly, PhD is Professor of Genetics at the University of Pennsylvania Perelman School of Medicine and Director of the Genetic Diagnostic Laboratory. Her clinical expertise encompasses molecular genetic testing for hereditary colon cancer, Li Fraumeni syndrome, Retinoblastoma (RB), uveal melanoma, Hemophilia A, and Hereditary Hemorrhagic Telangiectasia (HHT), with the laboratory serving as a national reference center for RB, HHT, and Hemophilia A testing. The laboratory is ABMG-accredited for clinical molecular genetics fellow training. Her educational background includes a B.S. in Physics (1974) and M.S. in Physics (1977) from Calcutta University, followed by a Ph.D. in Biophysics (1984) from the University of Calcutta. She completed postdoctoral training at Thomas Jefferson University (1985-1990) and a fellowship in the CHOP-UPENN Genetics Program (1996-1998), achieving FACMG certification in Clinical Molecular Genetics in 1999 with recertification in 2019. Ganguly's research focuses on the molecular genetics of ocular tumors, particularly retinoblastoma and uveal melanoma. Her retinoblastoma work investigates gene expression profiles of enucleated tumors to predict clinical response, metastasis potential, and retinal cell development origins. For uveal melanoma, her team develops gene signatures for metastasis prediction from fine needle aspirates and studies molecular mechanisms of tumor development, with significant findings linking chromosomal abnormalities (monosomy 3, 8q gain) to metastatic risk. She collaborates with Dr. Charles Stanley on congenital hyperinsulinism research, recently identifying a novel genomic region for autosomal dominant inheritance. Her extensive publication record demonstrates expertise in cancer genomics, molecular diagnostics, and translational research. Recent work includes developing epigenomic prognostic signatures for uveal melanoma (MethylSig-UM), characterizing Beckwith-Wiedemann syndrome phenotypes, and investigating mosaic variants in lymphatic disorders. Her research bridges basic science discoveries with clinical applications in molecular genetic testing. Ganguly actively trains clinical molecular genetics fellows through the ABMG-accredited program and collaborates with multiple institutions including Children's Hospital of Philadelphia. Current research initiatives include genomic analysis of uveal melanoma metastasis predictors, molecular basis of retinoblastoma tumorigenesis, and genotype-phenotype correlations in congenital hyperinsulinism and overgrowth syndromes. Her laboratory serves as a national reference center for specialized genetic testing in rare conditions.

Maria L. Petersonمشاهده پروفایل

دانشیار

• Animal Science
• Developmental Biology
• Epigenetics
• +۳ مورد دیگر

Dr. Maria L. Peterson is an Associate Professor in the Department of Animal and Veterinary Sciences at the University of Rhode Island (URI). Her research focuses on understanding how maternal nutritional, environmental, and health conditions during pregnancy influence offspring development, with a particular emphasis on pancreatic, muscle, and metabolic programming. She utilizes sheep, cattle, and pigs as model organisms, employing molecular techniques such as next-generation sequencing, RT-PCR, ELISAs, and histological analyses. Education: Postdoctoral Fellow, University of Connecticut (2017) Ph.D., University of Connecticut (2014) M.S., University of Connecticut (2011) B.S., University of Rhode Island (2009) Research Interests: Epigenetic mechanisms (e.g., DNA methylation) in maternal-offspring programming Impact of maternal nutrition on offspring pancreas, muscle, and cardiovascular systems Effects of maternal stress, parasites, and disease on fetal development Optimization of livestock management practices in Northeast agriculture Her work spans from basic science (e.g., multi-omics analyses) to applied research (e.g., pasture-fed sow nutrition). Recent studies explore transgenerational effects of maternal diet and the role of leptin/ghrelin signaling in offspring metabolism. Labs/Teams : Dr. Peterson leads a lab focused on maternal-fetal programming, collaborating with URI’s College of the Environment and Life Sciences and external institutions.

Darren A. Cusanovichمشاهده پروفایل

استادیار

• Functional Genomics
• Computational Biology
• Cellular Biology
• +۳ مورد دیگر

Darren A. Cusanovich is an Assistant Professor in the Department of Cellular and Molecular Medicine at the University of Arizona , with an additional appointment as an Assistant Research Scientist at the Asthma & Airway Disease Research Center (A2DRC) . His work bridges functional genomics , computational biology , and cellular biology , focusing on gene regulation in complex diseases like asthma using single-cell genomics technologies. Promotion: Elevated from Research Assistant Professor to Assistant Professor in 2021. Funding: Recipient of the NIGMS ESI MIRA R35 and UA Health Sciences Career Development Award . Research interests revolve around deciphering how the human genome regulates cellular diversity and how genetic/environmental factors perturb this regulation to drive diseases. His lab develops novel single-cell assays (e.g., txci-ATAC-seq) to study chromatin accessibility and gene-environment interactions in asthma , COVID-19 , and metabolic diseases . Scientific contributions include a groundbreaking Science paper on single-cell ATAC-seq assays and the creation of scalable tools like SGRN and Swab-seq for genomic analysis and SARS-CoV-2 surveillance. Awards: ESI MIRA R35 (NIGMS, 2020) UA Health Sciences Career Development Award (2020) Education includes a PhD in Human Genetics from The University of Chicago, postdoctoral work in Jay Shendure’s lab at the University of Washington, and a B.S. in Music Business from Loyola University New Orleans.

Brigid E. Greggمشاهده پروفایل

دانشیار

• Metabolic Diseases
• Nutritional Sciences
• Developmental Biology
• +۳ مورد دیگر

Brigid E. Gregg is an Associate Professor at the University of Michigan's Medical School in the Department of Pediatrics and the School of Public Health's Department of Nutritional Sciences. She also serves as Assistant Chair in the Department of Pediatrics. University: University of Michigan School: Medical School (Pediatrics) and School of Public Health (Nutritional Sciences) Academic Rank: Associate Professor Dr. Gregg's research focuses on perinatal programming of metabolic diseases, including how early-life nutrient stressors and maternal metabolic health influence offspring risk for obesity, diabetes, and metabolic syndrome. Her work combines animal models and human mother-infant cohorts to study molecular mechanisms in pancreatic beta-cell expansion, adipose tissue, and liver function. Recent publications highlight her studies on maternal nutrition (e.g., DHA enrichment, Mediterranean diet), diabetes treatment (GLP-1/GIP agonists), and the impact of gestational BPA exposure on islet development. The Gregg lab investigates lactation-period nutrient stressors and their long-term effects on metabolic health.

• Diabetes Research
• Biophysics
• Bioengineering
• +۴ مورد دیگر

Richard Benninger, PhD, serves as Assistant Professor at the University of Colorado Anschutz Medical Campus School of Medicine with joint appointments in Bioengineering and Pediatrics. He directs the Advanced Light Microscopy core facility and leads a multidisciplinary research program focused on diabetes mechanisms. Education: PhD, Imperial College of Science, Technology and Medicine (2006) Research Focus: The Benninger lab applies engineering principles to study pancreatic islets of Langerhans, investigating systems biophysics in diabetes, gap junction plasticity , cell heterogeneity , and advanced imaging techniques . Their work bridges optical microscopy , ultrasound imaging , and biophysical modeling to develop diabetes diagnostics and therapeutics targeting hormone release mechanisms. Publication Trends: Analysis of 15 recent publications reveals consistent focus on islet multicellular dynamics (73% of articles), gap junction regulation (60%), and imaging technology development (47%). Temporal trends show increasing emphasis on human islet studies (2017-2020) and translational applications for type 1 diabetes diagnostics. Scientific Awards: No awards were documented in the provided materials. Academic Service: Benninger actively contributes to diabetes research through the American Diabetes Association and Biophysical Society memberships. The text contains no information regarding graduate student mentorship or grant funding. Research Infrastructure: The Benninger lab operates as a collaborative engineering-medicine unit centered around the Advanced Light Microscopy core. Their technical capabilities integrate two-photon microscopy , calcium imaging , and computational modeling to analyze islet function across molecular, cellular, and tissue scales in both mouse and human models.

• Regenerative medicine
• Stem cell biology
• Pancreatic cell regeneration
• +۵ مورد دیگر

Juan Dominguez-Bendala, Ph.D., is a Research Professor of Surgery at the University of Miami Miller School of Medicine, within the DeWitt Daughtry Family Department of Surgery and the Diabetes Research Institute. Since 2001, he has led pioneering efforts in regenerative medicine and stem cell biology, focusing on pancreatic cell regeneration and type 1 diabetes therapy. Education: BSc in Biological Sciences, University of Seville (1993) MSc in Applied Molecular Biology and Biotechnology, University College London (1997) PhD in Gene Targeting in Embryonic Stem Cells, Roslin Institute, University of Edinburgh (2000) Research Interests: Dr. Dominguez-Bendala's lab is dedicated to developing regenerative strategies for type 1 diabetes, including stem cell differentiation into insulin-producing β-cells and islet regeneration. Key discoveries include the role of molecular oxygen in β-cell differentiation and the development of genetic fail-safe systems for stem cell transplantation. His collaborative work with Dr. Ricardo L. Pastori has advanced the understanding of human pancreatic ductal progenitor cells and their potential for therapeutic application. Scientific Contributions: His recent publications span high-impact journals such as Nature Communications , Cell Metabolism , and PNAS , focusing on real-time islet regeneration, single-cell transcriptomics of pancreatic progenitors, and innovative culture systems for pancreatic slices. These works collectively aim to translate basic science into clinical therapies for diabetes. Teaching & Mentorship: Although his primary role is research-focused, Dr. Dominguez-Bendala has mentored 30 undergraduate and 27 graduate students, directed 6 PhD projects, and supervised 8 postdoctoral associates. He also chairs the University of Miami's Embryonic Stem Cell Research Oversight (ESCRO) Committee.

• Beta-cell biology
• Insulin secretion
• Human islets
• +۳ مورد دیگر

Felicia Gerst is a Senior Scientist at the Helmholtz Diabetes Center and the Institute for Diabetes and Obesity (IDM). She earned her Habilitation at the Faculty of Medicine, University of Tübingen, in 2019, following postdoctoral and doctoral fellowships at the University Hospital Tübingen and the Graduate School GRK1302/2. Her research focuses on beta-cell biology, insulin secretion, and the interplay between pancreatic adipose tissue and metabolic diseases. Education & Career Habilitation (2019), Faculty of Medicine, University of Tübingen Postdoctoral Fellow (2007–2019), Internal Medicine IV, University Hospital Tübingen Doctoral Fellow (2004–2007), Institute of Physiology, University of Tübingen Dr. Gerst's research spans beta-cell function , insulin secretion dynamics , and pancreatic fat cell activity in health and disease. Her work integrates endocrinology , molecular biology , and diabetes pathophysiology , with recent studies exploring incretin-responsive organoids and free fatty acid receptor mechanisms. Her publications highlight trends in pancreatic adiposity , islet-adipose interactions , and hepatokine signaling in beta-cell dysfunction. Awards include the HUMAIN Award (InSphero, Switzerland) for functional organoid models. Scientific Awards HUMAIN Award (InSphero, Switzerland) Dr. Gerst leads the Islet Facility , contributing to networks like the German Center for Diabetes Research (DZD) and European Association for the Study of Diabetes (EASD). Grants include DDG Grant (2023) and DZD Grant (2018–2019) .

Maria Bettiniمشاهده پروفایل

استاد

• T cell biology
• autoimmunity
• tolerance
• +۴ مورد دیگر

Maria Bettini is a Professor of Pathology at the University of Utah School of Medicine and a faculty member in the Molecular Biology Program, where she investigates immunological mechanisms of autoimmunity with emphasis on type 1 diabetes pathogenesis. She earned her B.S. from East Tennessee State University and Ph.D. from Emory University, establishing expertise in T cell immunology and autoimmune disease models. Her research program centers on T cell-mediated destruction of pancreatic beta cells, focusing on regulatory T cell (Treg) function, T cell receptor signaling diversity, and metabolic-immune interactions. Using genetically modified mouse models, flow cytometry, and transcriptional analysis, her lab explores how self-tolerance fails in autoimmunity and identifies pathways for therapeutic intervention, particularly through Treg modulation. Analysis of her 15 most recent publications reveals dominant themes in TCR repertoire analysis, CAR-T engineering applications for autoimmunity, and novel mechanisms of Treg suppression in tissue-specific inflammation, with strong translational focus on diabetes therapeutics. Dr. Bettini has mentored numerous graduate students in the Molecular Biology Program and secured sustained funding from the National Institutes of Health for her work on autoimmune diabetes mechanisms and tolerance restoration strategies. Her laboratory maintains advanced capabilities in murine diabetes models, single-cell TCR sequencing, metabolic phenotyping, and antigen-specific T cell tracking, operating within the University of Utah's Department of Pathology immunology research cluster.