Lana Garmireمشاهده پروفایل
دانشیار
Lana Garmire, PhD is an Associate Professor with tenure in both the Department of Computational Medicine and Bioinformatics and the Department of Biostatistics at the University of Michigan School of Public Health. She leads the Garmire Group in Translational and Clinical Informatics, a multidisciplinary team focused on advancing bioinformatics methodologies for clinical applications. Dr. Garmire has established herself as a nationally and internationally recognized expert in translational bioinformatics, with particular expertise in single-cell sequencing technologies and integrative omics analysis. Dr. Garmire received her MA in Statistics (2005) and PhD in Computational Biology (2007) from UC Berkeley, followed by postdoctoral training at UC-San Diego (2008-2011). She began her academic career at the University of Hawaii Cancer Center in 2012, where she rapidly achieved tenure and was promoted to Associate Professor in 2017. In 2018, she moved to the University of Michigan to expand her research into multi-modal approaches combining genomics, electronic medical records, and pathological imaging analysis. Her research focuses on single-cell and spatial transcriptomics , integrative analysis of EMR/imaging/omics/clinic data , translational bioinformatics of cancers , prognosis and diagnosis prediction , actionable computational models , drug repositioning/repurposing , and women's and neonatal health research . Dr. Garmire's work bridges computational approaches with clinical applications, particularly in cancer and pregnancy-related conditions. An analysis of her recent publications reveals a strong emphasis on deep learning applications in single-cell data analysis , with multiple papers on imputation methods, survival prediction models, and tools for clinical translation. Her research has evolved from foundational bioinformatics methods to increasingly clinically focused applications, particularly in women's health and cancer therapeutics. The trend shows growing integration of multiple data types (multi-omics) and development of user-friendly tools for broader scientific adoption. Dr. Garmire has received numerous prestigious honors including the US Presidential Early Career Scientist and Engineer (PECASE) award in 2019 , the highest honor for early-career scientists in the United States, and election as a fellow of the American Institute of Medical and Biological Engineering (AIMBE) in 2022 . Her group has consistently produced high-impact publications in top journals including Nature, Cell, Genome Biology, and Nature Communications. As a dedicated mentor, Dr. Garmire has trained over 90 researchers including Assistant Professors, MD fellows, postdocs, graduate students, and undergraduates from diverse academic backgrounds. She has successfully secured substantial funding through multiple concurrent NIH R01 grants from NICHD, NLM, and other institutes, as well as a recent R03 grant from the NIH Office of the Director on personalized cancer drug repurposing (July 2025). Her group currently operates a 10x Genomics Chromium system for single-cell RNA and DNA sequencing, supporting both internal research and external collaborations. The Garmire Group maintains an active research program with lab members engaging in diverse projects spanning computational methodology development, cancer research, women's health, and tool building. The group culture emphasizes inclusivity and diversity, with active participation in university-wide initiatives supporting women in STEM and underrepresented groups in science.
