جست‌وجوی استاد و پژوهشگر

• Microbial Biofilms
• Oral Microbiology
• Fungal Pathogenesis
• +۵ مورد دیگر

Dr. Christopher Delaney serves as a Lecturer in Biomedical Sciences within the Dental School at the University of Glasgow, where he maintains an active research program focused on microbial biofilms and oral microbiology. His academic work bridges clinical dentistry with fundamental microbiological research, particularly examining fungal-bacterial interactions in polymicrobial communities. Dr. Delaney's research interests center on microbial biofilm dynamics, with specialization in Candida species pathogenesis, interkingdom interactions, and antimicrobial resistance mechanisms. His laboratory employs multi-omics approaches including transcriptomics and metabolomics to investigate host-pathogen relationships in oral and systemic infections, with particular emphasis on how biofilm heterogeneity influences disease outcomes and treatment efficacy. Current research initiatives include grants from Tenovus Scotland (2024-2026) examining the metagenomic profile of tonsil and oral flora in tonsillitis patients, and a British Endodontic Society project (2024-2027) analyzing endodontic lesions for targeted biofilm disruption strategies. These projects reflect his translational approach to developing clinical solutions for biofilm-related infections. Dr. Delaney supervises doctoral research, currently guiding Muhanna Ali M Alshehri's investigation of Candida albicans interactions with oral microorganisms. His educational contributions include implementing virtual laboratory simulations to enhance student engagement across undergraduate and postgraduate cohorts, demonstrating his commitment to innovative pedagogical approaches in microbiology education.

• Chemical Biology
• Cancer Research
• Metal Biology
• +۶ مورد دیگر

Raphaël Rodriguez serves as CNRS Research Director, Team Leader of the Biomedicine group, and Deputy Director of the Chemical Biology of Cancer research unit (U1339/UMR3666) at Institut Curie in Paris. His interdisciplinary work bridges synthetic chemistry and molecular biology to investigate metal ion-driven cellular processes. His research focuses on metal-mediated cell adaptation in cancer and inflammation, revealing CD44's role in copper/iron uptake that regulates epigenetic programming and metabolic rewiring. Key innovations include identifying lysosomal iron as a ferroptosis trigger and developing first-in-class small molecules targeting metal-dependent pathways for therapy-resistant cancers. Recent publications demonstrate consistent leadership in Metal ion trafficking in disease states Ferroptosis modulation for cancer therapy Chemical intervention in inflammation/ageing with major contributions to understanding copper's role in NAD(H) redox cycling and iron's transcriptional regulation. Award highlights: CNRS Silver Medal (2024) Liliane Bettencourt Prize (2023) Klaus Grohe Prize for drug development (2022) Tetrahedron Young Investigator Award As Deputy Director of Research Unit, Rodriguez leads grant-funded projects developing chemical probes for cell adaptation mechanisms. His team's work on remodelin, ironomycin, and salinomycin has spawned multiple biotech ventures. Current efforts focus on translating metal-targeting molecules into clinical applications for therapy-resistant cancers and inflammatory disorders through Institut Curie's innovation ecosystem. The Biomedicine team operates within Institut Curie's Chemical Biology of Cancer unit, utilizing integrated chemical biology platforms including click chemistry-based fluorescent tagging, multi-omics analysis, and organic synthesis facilities to dissect metal-dependent pathways in melanoma, pancreatic cancer, and acute kidney injury models.