Allen Holder is a Professor of Mathematics at Rose-Hulman Institute of Technology with research affiliations at Indiana University School of Medicine, Cancer Therapy Research Center (San Antonio), and Huntsman Cancer Center (Salt Lake City). His work bridges optimization theory with real-world applications in medicine, biology, and industrial systems. Education PhD, University of Colorado-Denver, 1998 MS, University of Southern Mississippi, 1993 BS, University of Southern Mississippi, 1990 Dr. Holder specializes in mathematical programming applied to computational biology (protein structure alignment, metabolic networks), medical physics (radiotherapy optimization), and industrial engineering (foundry scheduling). His cross-disciplinary approach has driven the establishment of Rose-Hulman's biomathematics major and enabled breakthroughs like a 1000x faster protein analysis algorithm developed with Dr. Yosi Shibberu. His 2011-2015 publications reveal a consistent pattern of applying operations research to high-impact biological and medical challenges, particularly in genome-scale modeling and radiation oncology optimization, while maintaining industrial applications in scheduling. Scientific Recognition Board of Trustees Outstanding Scholar (2015) 4-time Blue Key Favorite Professor (2001,2003,2005,2006) INFORMS Moving Spirit Award (2003) 2-time Alpha Lambda Delta Professor of the Month (2000,2003) Dr. Holder has mentored nearly 50 undergraduate researchers and serves as editor for multiple publications. His collaborative grants span medical centers and industrial partners, focusing on translating optimization theory into clinical and manufacturing solutions. He leads cross-institutional teams including Rose-Hulman biology/chemistry faculty, Indiana University medical researchers, and cancer center specialists, driving translational projects from algorithm development to clinical implementation.
