جستجوی استاد راهنمای دانشگاهی

Harris H. Wang is an Associate Professor in the Department of Systems Biology and Department of Pathology and Cell Biology at Columbia University's Vagelos College of Physicians and Surgeons, where he also serves as Interim Chair of Systems Biology. He is affiliated with the Center for Computational Biology and Bioinformatics (C2B2) and the Integrated Program in Cellular, Molecular and Biomedical Studies (CMBS). B.S., Physics and Mathematics, MIT Ph.D., Biophysics, Harvard University Dr. Wang's research lies at the intersection of systems and synthetic biology, focusing on developing foundational technologies for genome engineering, microbiome manipulation, and synthetic genomics. His lab pioneers methods such as MAGE, MAGIC, CAST, and CAMII to enable high-throughput genetic manipulation, in situ microbiome engineering, and AI-driven microbial culturomics. Key research themes include understanding microbial community dynamics, engineering cellular memory systems, designing biocontained genetic circuits, and applying synthetic biology to human health challenges in personalized medicine and infectious disease. His recent publications reveal a strong trend in spatial and functional metagenomics, CRISPR-based microbiome editing, and synthetic biology tools for data storage and genetic stability. The articles span high-impact journals like Nature , Science , and Nature Biotechnology , reflecting his leadership in developing scalable, programmable biological systems. Scientific Awards: NIH Director’s Early Independence Award Forbes 30 Under 30 in Science Sloan Research Fellowship NSF CAREER Award ONR Young Investigator Award Burroughs Wellcome Fund PATH Award Schaefer Scholar Blavatnik National Award Vilcek Prize PECASE Dr. Wang has advised numerous PhD and postdoctoral researchers, many of whom have gone on to independent scientific careers. His lab is supported by major grants from NIH, NSF, DARPA, DOE, and foundations including the Bill & Melinda Gates Foundation and CZ Biohub NY. He is actively involved in educational initiatives, including organizing Columbia’s iGEM team and the Cold Spring Harbor Laboratory Synthetic Biology course. The Wang Lab is based at the Columbia University Irving Medical Center and is part of national consortia such as the Engineering Biology Research Consortium (EBRC) and the Genome Project-Write (GP-Write) initiative. The lab develops and applies cutting-edge technologies in automation, machine learning, and synthetic biology to engineer microbiomes for applications in medicine, global health, and climate change.

• Systems Biology
• Synthetic Biology
• Genome Engineering
• +۱۷ مورد دیگر

Hauke Smidt is a Personal Professor at Wageningen University & Research, affiliated with the Molecular Ecology group within the Faculty of Veterinary Medicine and Animal Sciences. His research focuses on microbial ecology, particularly gut microbiota dynamics, antibiotic resistance, environmental microbiology, and the One Health framework. Smidt has supervised over 50 PhD students and contributed to 519 publications, including studies on microbiome resilience, fermented food impacts, and bioremediation strategies. Education and affiliations include leadership roles in projects addressing antimicrobial resistance, pig health, and drinking water microbiology. His work spans collaborations across Europe and Asia, with notable contributions to understanding microbial community responses to environmental stressors and dietary interventions. Smidt is actively involved in public outreach, as seen in media contributions discussing microbiome research and health benefits. Key projects include aquifer treatment for drinking water, microbiome simulation models, and combating plant pathogens. His awards and recognition are not explicitly listed, but his extensive publication record and project leadership highlight significant academic impact.

• Microbiology
• Environmental Microbiology
• Gut Microbiota
• +۴ مورد دیگر

Dr. Praneet Prakash is a Researcher in the Department of Applied Mathematics and Theoretical Physics at the University of Cambridge, working under Prof. Raymond Goldstein. His research focuses on interdisciplinary approaches combining microfluidics, microscopy, and theoretical physics to study biological systems. Key areas include microbial motility, active matter dynamics, and the interplay between physics and living systems. He utilizes experimental techniques such as microfluidics and advanced microscopy to investigate phenomena like bacterial swimming, nutrient exchange in microbial communities, and growth oscillations in filamentous fungi. His work bridges Soft Matter Physics, Statistical Mechanics, and Biophysics, with applications ranging from understanding microorganism behavior to developing biosensor technologies. Recent studies explore phototactic algae behavior, ciliary surface interactions in animalcules, and adaptive motility in marine microorganisms. Publications highlight contributions to microbial ecology, active matter systems, and biophysical modeling. While no formal awards are listed, his research has been published in high-impact journals like Journal of the Royal Society Interface and Physical Review Fluids . He is affiliated with the Biological Physics and Mechanics research group and maintains an active presence on academic platforms like Twitter and LinkedIn.

• Biophysics
• Soft Matter Physics
• Statistical Mechanics
• +۳ مورد دیگر

Ting Lu is an Associate Professor at the University of Illinois at Urbana-Champaign in the School of Biomedical and Translational Sciences, focusing on microbial synthetic biology and systems biology. Their research bridges biology, engineering, and physics to reprogram cellular functionalities through gene regulatory networks. Ph.D. in Biophysics, University of California at San Diego (2007) B.S. in Physics, Zhejiang University (2002) Ting Lu's work explores microbial ecosystems, synthetic gene circuits, and their applications in biotechnology and medicine. By combining experimental approaches with mathematical modeling, they investigate bacterial communication networks, metabolic pathways, and spatial dynamics in microbial communities. Selected research trends include microbial consortia engineering for bioremediation and bioproduction, complexity reduction in microbiomes, and predictive modeling of synthetic gene networks. Their publications span high-impact journals such as Nature Communications , Nature Chemical Biology , and eLife . Fellow, American Institute for Medical and Biological Engineering (2022) Future Insight Prize (2021) Donald Biggar Willett Faculty Scholar (UIUC) (2020) NIH Maximizing Investigators' Research Award (2019) NSF CAREER Award (2015) AHA National Scientist Development Grant (2012) Ting Lu's lab has received grants from NIH, NSF, ONR, and industry partners. They offer undergraduate research opportunities in synthetic and systems biology, and teach advanced courses such as BIOE 430 - Intro Synthetic Biology and BIOE 432 - Systems Biology .

• Synthetic Biology
• Systems Biology
• Quantitative Biology
• +۵ مورد دیگر

Vikramaditya G. Yadav is an Associate Professor at the University of British Columbia (UBC) in the Department of Chemical and Biological Engineering, Faculty of Applied Science. He directs the Master of Engineering Leadership (MEL) Program in Sustainable Process Engineering and leads the BioFoundry research group. Education: B.A.Sc., University of Waterloo (2007) Ph.D., Massachusetts Institute of Technology (2013) Postdoctoral Associate, Harvard University (2014) His research spans sustainable chemical manufacturing, metabolic engineering, and biotechnology. Key areas include: Designing biosynthetic enzymes for biomass valorization Developing bioremediation strategies for industrial water quality Creating innovative drug delivery systems and tissue engineering solutions Advancing synthetic biology for pharmaceutical and bioenergy applications His recent work focuses on ocular drug delivery, cannabinoid biosynthesis in E. coli, lignin-based nanoparticles for cancer therapy, and computational analysis of plant secondary metabolites. Collaborations with start-ups, industry, and medical labs drive innovation in Canada's bioeconomy. Professional Leadership: Chair, Biotechnology Division of the Chemical Institute of Canada Associate Editor, The Canadian Journal of Chemical Engineering He is affiliated with UBC's BioProducts Institute and contributes to project-based learning pedagogy.

• Biocatalysis
• Bioremediation
• Bioprocess engineering
• +۱۵ مورد دیگر

David H. Sherman is the Hans W. Vahlteich Professor of Medicinal Chemistry at the University of Michigan, holding joint appointments in the College of Pharmacy (Department of Medicinal Chemistry), Medical School (Microbiology & Immunology), and College of Literature, Science, and the Arts (Chemistry). He leads the Sherman Lab at the Life Sciences Institute and co-founded the Natural Products Discovery Core. His research focuses on natural product discovery, biosynthetic pathways, and drug development for infectious diseases, cancer, and neurological disorders. Education: PhD in Synthetic Organic Chemistry from Columbia University (1981), BA in Chemistry from UC Santa Cruz (1978). Postdoctoral research at MIT (1984). Research interests include microbial secondary metabolites, enzymatic catalysis (e.g., C-H functionalization, polyketide assembly), and high-throughput drug screening. He pioneered a microbial natural product library with over 50,000 samples. Current projects emphasize developing macrolide antibiotics and advancing compounds toward clinical trials through the Natural Products Biosciences Initiative. Collaborations span global institutions, with a focus on biodiversity conservation and capacity-building in low-income nations. He has mentored 67 PhD students, 60 postdocs, and 85+ undergraduates, fostering interdisciplinary training in chemical biology and microbial biochemistry. Labs/Teams: Sherman Lab (Life Sciences Institute), Center Member at Samuel and Jean Frankel Cardiovascular Center, Center for Computational Medicine and Bioinformatics, Rogel Cancer Center.

• Natural Products Chemistry
• Medicinal Chemistry
• Biosynthesis
• +۴ مورد دیگر

Professor Daniel Segrè is a faculty member at Boston University, holding the title of Professor of Biology, Bioinformatics, and Biomedical Engineering. His research focuses on systems biology, microbial ecology, and metabolic engineering, with an emphasis on understanding complex biological networks and their applications in bioenergy and biomedicine. Segrè leads the Segre Lab ( segrelab.bu.edu ), where theoretical and computational approaches are applied to study metabolism, microbial interactions, and synthetic biology. Segrè earned his PhD from the Weizmann Institute of Science, Israel. His work bridges fundamental science and applied engineering, addressing topics such as microbial community dynamics, metabolic pathway design, and environmental microbiome applications. Research Interests: Systems biology of metabolism, evolution of biochemical networks, microbial interactions, bioinformatics, and environmental microbiome engineering. His lab develops computational models (e.g., COMETS) to simulate microbial ecosystems and design synthetic microbial communities for climate change mitigation and bioenergy production. Teaching: Courses include BE 777 (Computational Genomics), BF 821 (Bioinformatics Seminar), and BF 571 (Dynamics and Evolution of Biological Networks). These courses reflect his expertise in integrating computational methods with biological systems analysis.

• Systems Biology
• Metabolic Engineering
• Microbial Ecology
• +۷ مورد دیگر

Professor Jianhua Guo is a faculty member at The University of Queensland (UQ), holding the position of Professor and UQ Amplify Fellow in the Australian Centre for Water and Environmental Biotechnology (ACWEB). He is also the ACWEB Deputy Director - Research. His research focuses on integrating process engineering, environmental microbiology, and biotechnology to develop sustainable solutions for contaminant removal in water and wastewater systems. He is a pioneer in studying the environmental dimension of antimicrobial resistance (AMR), particularly how non-antibiotic pharmaceuticals and chemicals contribute to AMR spread. His groundbreaking work has been featured in over 100 media outlets and has secured over $14M in research funding. He has published over 200 peer-reviewed articles in journals like Nature Microbiology , Water Research , and Environmental Science & Technology . His accolades include the 2013 DECRA and 2017 ARC Future Fellowship. He serves as an editor for Journal of Hazardous Materials and Water Science & Technology . Research Interests Environmental AMR and microbial ecology Methane-based biotechnology and bioconversion Nitrogen cycling microorganisms Bioremediation and biofilm reactors Microplastics and health risks Wastewater treatment innovations Grants & Funding $14M+ in ARC Discovery/Linkage grants and industry partnerships ARC Training Centre for Environmental and Agricultural Solutions to Antimicrobial Resistance (CEA-StAR) Dual-membrane upgrading and anaerobic alkane oxidation projects Awards 2013 DECRA 2017 ARC Future Fellowship Supervision Prof. Guo actively supervises PhD and master’s students in areas like AMR mitigation, methane-based bioreactors, and microbial ecology. Notable supervised projects include studies on antibiotic resistance in wastewater, novel disinfection processes, and microbial oxidation of gaseous alkanes. Labs & Teams He leads research teams within ACWEB and collaborates with the Queensland Alliance for Environmental Health Science. His lab focuses on cutting-edge technologies like membrane biofilm reactors and gas fermentation systems.

• Environmental Biotechnology
• Antimicrobial Resistance (AMR)
• Wastewater Treatment
• +۷ مورد دیگر

John M. Woodley is a distinguished Professor in the Department of Chemical and Biochemical Engineering at the Technical University of Denmark (DTU), where he leads research at the PROSYS - Process and Systems Engineering Centre and contributes to the DTU Microbes Initiative. With over 30 years of experience, he has established himself as a leading expert in biocatalysis and bioprocess engineering, with research spanning both theoretical and experimental work across multiple scales. His primary research interests focus on the interface of bioprocess engineering, process chemistry, and reaction engineering. Dr. Woodley's work encompasses multi-step biocatalysis (including systems biocatalysis and flow chemistry), downstream processing from biocatalytic reactors and fermentations (including ISPR), modeling tools for bioprocess assessment (thermodynamics, kinetics, process simulation, economic evaluation), and bio-oxidations (including oxygen supply methods). His enzymatic investigations particularly target alcohol oxidases, carbohydrate oxidases, cytochrome P450s, Baeyer-Villiger monooxygenases, and transaminases. His research portfolio demonstrates consistent innovation in sustainable chemical production, with particular emphasis on enzymatic synthesis of pharmaceuticals and chemicals from renewable resources. Analysis of his recent publications reveals a strong focus on overcoming industrial implementation challenges, particularly regarding enzyme stability in various reactor environments, optimization of multi-enzyme systems, and scale-up methodologies for biocatalytic processes. Dr. Woodley actively supervises multiple PhD students and leads several significant research projects, including 'P450-based biocatalytic processes for the pharmaceutical industry' (2025-2028), 'Integrated model for up- and downstream bioprocess intensification' (2024-2027), and 'ENFACE: A tool for prediction of enzyme stability at gas-liquid interfaces' (2024-2027). His work has resulted in an impressive publication record of 781 research outputs across various formats, including journal articles, book chapters, and conference proceedings. His research group operates within the Department of Chemical and Biochemical Engineering at DTU, utilizing advanced facilities for biocatalysis research, including specialized reactor systems for studying gas-liquid interfaces, computational modeling resources, and laboratories for enzyme characterization and bioprocess development. Through his leadership in the PROSYS center, he contributes to DTU's strategic focus on sustainable process technologies and systems engineering.

• Biocatalysis
• Bioprocess Engineering
• Enzyme Technology
• +۶ مورد دیگر

Hyun (Michel) Koo is a Professor at the University of Pennsylvania School of Dental Medicine , with affiliations in the Department of Orthodontics , Division of Community Oral Health , and Division of Pediatric Dentistry . As Co-Founder and Co-Director of the Center for Innovation & Precision Dentistry (CiPD) , he leads interdisciplinary efforts merging bioengineering, nanotechnology, and oral health research. Education : DDS and PhD Research Focus : Biofilms, bacterial-fungal interactions, and nanotechnology for oral disease prevention Leadership : Co-Director of CiPD; key roles in training programs like NIDCR-sponsored R90 and T90/R90 Dr. Koo’s research explores biofilm mechanisms in oral infectious diseases, particularly childhood caries, through engineering methods and microrobotics . His team developed micron-scale robots for automated biofilm eradication and FDA-approved nanoparticles for caries prevention. Collaborations with Penn Engineering, including Dr. Daeyeon Lee and Dr. Kacy Cullen, emphasize translational approaches. The 15 most recent publications highlight his work in nanorobotics , interkingdom biofilms , and precision diagnostics . Articles span 2025–2024 and address topics like adaptive micromotors , biofilm matrix degradation , and single-cell microbial interactions . These emphasize his focus on targeted therapies and biofilm microenvironment engineering . Key Awards : Elected Fellow, American Association for the Advancement of Science (AAAS) IADR Distinguished Scientist Award for innovative dental research Dr. Koo trains next-generation researchers through the CiPD NIDCR T90/R90 Postdoctoral Training Program , mentoring fellows like Smruti Nair (ACE2 Chewing Gum development) and Zhi Ren (K99 awardee). His work intersects with Penn Health-Tech, CT3N , and Penn Institute for Biomedical Informatics , fostering transdisciplinary innovation.

• Biofilms
• Oral Infectious Diseases
• Nanotechnology
• +۳ مورد دیگر

Dr. Monica E. McCallum is an Assistant Professor of Chemistry in the Department of Chemistry at the University of Pennsylvania’s School of Arts & Sciences. Her research focuses on understanding the biochemical origins of natural products and their roles in microbial communication. She leads the McCallum Lab, which employs interdisciplinary approaches combining organic synthesis, biochemistry, microbiology, and microscopy to study microbial natural products in their native contexts. Education: 2016 – Postdoctoral Fellow at Harvard University under Prof. Emily P. Balskus 2016 – PhD in Organic Chemistry from Baylor University 2013 – PhD Candidate at Colorado State University 2011 – B.S. in Chemistry from University of California, Irvine Research Interests: Dr. McCallum’s work bridges organic synthesis and microbiology to decode microbial metabolite functions. Key themes include: Synthesizing complex natural products and their biosynthetic precursors Discovering novel enzyme-catalyzed reactions Unraveling microbial communication mechanisms via natural products Investigating environmental microbial community dynamics Lab & Collaborations: The McCallum Lab emphasizes interdisciplinary collaboration, integrating techniques from organic chemistry, molecular biology, and microscopy to study natural products in situ. Current projects focus on diazeniumdiolate biosynthesis pathways and enzymatic detoxification of marine toxins.

• Microbial Chemistry
• Natural Products Synthesis
• Biochemistry
• +۳ مورد دیگر

Paul O'Toole is a Professor of Microbial Genomics and Principal Investigator at the APC Microbiome Ireland, University College Cork. His research focuses on the gut microbiome's role in health, aging, and disease, particularly in the context of diet and probiotics. He leads projects like the ELDERMET study on elderly nutrition and the NU-AGE project exploring Mediterranean diets' anti-aging effects. He holds a BA (Mod.) from Trinity College Dublin and a PhD from Lund University, with postdoctoral training in Canada and New Zealand. Key grants include studies on dairy-derived microbiota, probiotic strain improvement, and microbiome analysis in aging populations. He has published extensively on Lactobacillus genomics, gut-brain interactions, and microbiome-driven health outcomes. His work bridges fundamental microbiology with clinical applications, emphasizing translational research. Scientific highlights include discovering microbiome links to cognitive decline, demonstrating dietary modulation of gut microbes to combat obesity, and identifying keystone species in healthy aging. He advocates for sustainability in conservation and food systems, reflecting his interdisciplinary approach to global health challenges.

• Microbial Genomics
• Gut Microbiome
• Aging and Healthy Aging
• +۴ مورد دیگر

Amilcare Porporato is the Thomas J. Wu '94 Professor of Civil and Environmental Engineering at Princeton University, with joint appointment at High Meadows Environmental Institute. His research integrates hydrology, ecology, and thermodynamics to study soil-water interactions and sustainable resource management. Education includes: Ph.D. Polytechnic of Milan (1996) M.S. Civil Engineering, Polytechnic of Milan (1992) Research explores nonlinear hydrologic systems, soil moisture dynamics, ecohydrology, and environmental complexity using theoretical and experimental approaches. His work advances understanding of water-biota interactions across scales from pore-level processes to landscape evolution. Honors and Awards: Hydrologic Sciences Award, AGU Borland Lecturer American Geophysical Union Fellow Inaugural Landolt Chair, EPFL Teaches courses on Environmental Thermodynamics (ENV 385/CEE 385) and Ecohydrology (CEE 587/ENV 587).

• Ecohydrology
• Soil-Atmosphere Interaction
• Hydrologic Time Series
• +۲ مورد دیگر

Angela D. Kent is a Professor in the Department of Natural Resources and Environmental Sciences at the University of Illinois Urbana-Champaign, where she also serves as Director of the Program in Ecology, Evolution, and Conservation Biology within the School of Integrative Biology. She is affiliated with the Carl R. Woese Institute for Genomic Biology. Her research focuses on microbial communities in agroecosystems and natural environments, particularly their roles in nitrogen cycling, soil health, and sustainable bioenergy production. Key research interests include microbial interactions in plant-microbe systems, the impact of genetic variation in crops on microbial processes, and the ecological and biogeochemical implications of soil microbiomes. She has authored over 99 publications and supervised datasets on topics such as denitrification dynamics, rhizosphere microbiome assembly, and microbial contributions to nitrogen retention. Dr. Kent has received the NACTA Educator Award (2012) and has contributed to high-impact studies on topics like microbial community responses to environmental stressors and the application of stable isotopes in bioenergy research. Her work bridges microbial ecology, agronomy, and environmental science, emphasizing practical solutions for sustainable agriculture and ecosystem management.

• Microbial Ecology
• Nitrogen Cycling
• Agroecosystems
• +۳ مورد دیگر

Tanja Narancic is an Assistant Professor at the School of Biomolecular and Biomedical Science at University College Dublin (UCD). She is also an academic collaborator at the Bioeconomy Research Centre BiOrbic, where she coordinates multiple research projects among PIs, PostDocs, PhD students, and designs projects proposed by industrial partners. Dr. Narancic earned her PhD in Applied Microbiology from the University of Belgrade, Serbia in 2012, followed by postdoctoral research at the Institute of Molecular Genetics and Genetic Engineering in Belgrade. In 2013, she joined University College Dublin as a Postdoctoral Research Fellow under Prof. Kevin O'Connor, where she investigated microbial metabolic pathways using proteomics, metabolomics, and synthetic biology tools as part of FP7 and H2020 projects. She became a Research Fellow at BiOrbic in 2019 before advancing to her current position as Assistant Professor. Her research focuses on elucidating bacterial metabolism and leveraging synthetic biology tools to exploit bacteria for producing high-value products. Key research areas include: Proteomics, Metabolomics, and Transcriptomics for microbial pathway analysis Metabolic engineering for bioproduction Biocatalysis and enzyme optimization Protein engineering and purification Polyhydroxyalkanoate (PHA) production from waste streams Plastic upcycling and biodegradation technologies Dr. Narancic's publication record demonstrates a strong focus on converting plastic waste into valuable biodegradable materials through innovative biotechnological approaches. Her recent work has centered on developing microbial systems for upcycling polyethylene terephthalate (PET), polyolefins, and other recalcitrant plastics into polyhydroxyalkanoates (PHAs) and other high-value products. She has made significant contributions to understanding the metabolic pathways involved in plastic monomer conversion and has developed engineered strains with enhanced capabilities for plastic upcycling. As a principal investigator, Dr. Narancic leads multiple significant research projects including the Ad Astra Studentship (2023-2028), the UPLIFT project on sustainable plastics for food packaging (2021-2025), and the PROMOFER project (2024-2028) on optimizing PHB production. She also serves as a reviewer for numerous prestigious journals including Enzyme and Microbial Technology, Journal of Applied Microbiology, and Microbial Biotechnology. Her teaching portfolio includes coordination of multiple modules such as Bioprocessing, Metabolism and Disease, and SynBio for Bioeconomy, demonstrating her commitment to educating the next generation of scientists in both fundamental and applied aspects of biomolecular science.

• Microbiology
• Biochemistry
• Synthetic and systems biology
• +۸ مورد دیگر