جستجوی استاد راهنمای دانشگاهی

Mark Wallace is a Professor of Chemistry at King's College London, affiliated with the Department of Chemistry and the Faculty of Natural, Mathematical & Engineering Sciences. He holds a Royal Society University Research Fellowship (2005–2016) and has been a lecturer at Oxford University before joining King's in 2016. His research focuses on membrane protein function and artificial membrane mimics, combining optical microscopy and nanotechnology. He earned a PhD from the University of Cambridge (2002) and postdoctoral training at Stanford University and the National Institute for Medical Research. Key research interests include membrane protein dynamics, lipid bilayer engineering, and single-molecule imaging. He has pioneered techniques like droplet interface bilayers and interferometric scattering microscopy. His work has led to patents and applications in molecular sensing and medical research. Awards include the 2002 Gregorio Weber Prize and the 2015 RSC Norman Heatley Award. He is actively involved in public outreach, including video podcasts and educational competitions. Recent publications emphasize artificial ion channels, nanoparticle formation monitoring, and mitochondrial protein dynamics. His lab collaborates with institutions like the London Centre for Nanotechnology and the Rosalind Franklin Institute. Over 30 students and researchers have been mentored, with active grants from EPSRC, Wellcome Trust, and BBSRC.

• Membrane Biology
• Biophysics
• Optical Microscopy
• +۳ مورد دیگر

Professor Thomas Meier is a Visiting Professor at the Department of Life Sciences, Imperial College London (since 2015), and Director of the Centre for Structural Biology (2017–2021). He leads research on ATP synthase structure, drug targets for tuberculosis, and molecular mechanisms of disease. Previously, he was a Group Leader at the Max-Planck-Institute of Biophysics (2006–2015) and ETH Zurich's Institute of Microbiology. His work combines structural biology (X-ray crystallography, electron microscopy) with biochemical studies. Education: Dr. sc. nat. (2002) and Dipl. sc. nat. (1998) from ETH Zurich. Awards include the Wellcome Trust Investigator (2015–present). Research focuses on ATP synthase's role in energy conversion, drug development, and structural biology. His lab includes postdocs and students like Lisa Uhrig and Anthony Cheuk. Key affiliations: Centre for Structural Biology, Membrane Biology Group, and Bacterial Pathogenesis studies. Languages: German, English, French (fluent), Latin (read/write). Publications span structural biology, planetary science, and drug discovery. His work on ATP synthase inhibitors for TB has clinical implications, while astrophysical studies explore planetary formation via giant impacts.

• Structural Biology
• Biochemistry
• Microbiology
• +۵ مورد دیگر

Professor Tim Williams is Professor of Veterinary Clinical Pathology at the Department of Veterinary Medicine, University of Cambridge, and Director of Studies in Veterinary Medicine at Fitzwilliam College. He is also a visiting research fellow in the Karet laboratory at the Cambridge Institute of Medical Research. His research focuses on extracellular vesicles in renal and urinary tract disorders, with particular emphasis on: The utility of extracellular vesicles as biomarkers for renal diseases The clinical significance of the bactericidal activity of urinary exosomes Novel biomarkers for chronic kidney disease in cats Potential biomarkers for urothelial cell carcinoma in dogs His work bridges veterinary clinical pathology, molecular biology, and translational medicine with applications in feline and canine medicine. Recent publications demonstrate his focus on identifying differentially expressed proteins and microRNAs associated with extracellular vesicles in disease states, spanning from fundamental bactericidal properties to clinical applications in companion animals. Professor Williams has received the Society for Comparative Endocrinology award for Excellence in the Advancement in Veterinary Endocrinology in both 2011 and 2015. He supervises multiple graduate students and maintains extensive collaborations across Cambridge departments and international institutions including Royal Veterinary College, Tufts University, and Shanghai Jiao Tong University. His research is supported by PetPlan Charitable Trust, BSAVA Petsavers, and the European College of Veterinary Clinical Pathology. As leader of the Extracellular Vesicle Research Group, Professor Williams investigates the role of extracellular vesicles in disease processes and their potential as diagnostic and therapeutic tools, with particular focus on translational applications from veterinary to human medicine.

• Extracellular vesicles
• Kidney disease
• Endocrinopathies
• +۵ مورد دیگر

Professor Paul C. Bressloff holds the Chair in Applied Mathematics and Stochastic Processes at Imperial College London's Department of Mathematics within the Faculty of Natural Sciences. His research focuses on stochastic and non-equilibrium processes, particularly in molecular and cell biology, utilizing tools from probability theory, statistical physics, and dynamical systems. He authored a seminal textbook Stochastic Processes in Cell Biology (Springer), with a 2nd edition published in 2022. Previously, he led the graduate program in mathematical biology at the University of Utah from 2001 to 2023. Research interests include stochastic multi-particle systems, active particles, phase separation, and diffusion across semi-permeable interfaces. His work spans applications in neural field theory, cytoneme-mediated morphogenesis, and protein trafficking. He is affiliated with the Biomathematics Group and Mathematical Physics Group at Imperial. Recent articles explore stochastic resetting in search processes, narrow-capture problems, and hybrid models of switching diffusions. His advising includes over 20 graduate students, many now faculty in mathematical biology. His contributions bridge applied mathematics and biological systems, emphasizing interdisciplinary approaches to complex stochastic phenomena.

• Applied Mathematics
• Mathematical Physics
• Neurosciences
• +۴ مورد دیگر

Sarah Lummis is a Professor in the Department of Biochemistry at the University of Cambridge. Her research focuses on understanding the structure-function relationships of Cys-loop ligand-gated ion channels (pLGICs), which are critical for neurotransmission and targets for pharmaceuticals. Her work addresses how structural features of these receptors influence their function and drug interactions. Research interests include ion channel biology, molecular pharmacology, and structural biology. Key publications investigate residues affecting receptor activity in 5-HT3 receptors, glycine receptors, and the prokaryotic channel ELIC. Her studies contribute to drug development for neurological disorders like epilepsy and Alzheimer's disease. Contact: sl120sec@bioc.cam.ac.uk | Group accepts interns, students, and researchers. Located at the Hopkins Building, Downing Site, Cambridge.

• Neuroscience
• Biochemistry
• Structural Biology
• +۳ مورد دیگر

Simon Webb is a Professor of Organic Chemistry at the University of Manchester, leading the Organic Chemistry Group within the School of Chemistry. His research focuses on molecular self-assembly to create biomimetic materials, with key themes including membrane recognition, synthetic ion channels, and magnetically responsive biomaterials. He earned his PhD from the University of Cambridge and has held academic positions since 2002. His work bridges organic chemistry, nanotechnology, and biomedicine, contributing to sustainable development through advanced materials in medicine and biotechnology. Education: B.Sc./M.Sc. Chemistry, Auckland University (1990–1994) PhD, University of Cambridge (1994–1997) Research Interests: Membrane communication via synthetic ion channels Magnetic nanoparticle-vesicle assemblies for drug delivery Peptide-based foldamers for signal transduction His lab develops materials that mimic biological membranes, such as magnetically triggered drug delivery systems (MNPVs) and foldamer-based sensors. Collaborations span advanced materials, biotechnology, and medical research. Current projects include exploring cooperativity in multivalent ligand binding and lipid raft dynamics. Publications highlight innovations in foldamer design, supramolecular arrays, and enzyme-responsive materials. His work is supported by grants and contributes to UN Sustainable Development Goals in health and advanced materials.

• Organic Chemistry
• Biomaterials
• Nanotechnology
• +۷ مورد دیگر

Dr. Martin Anthony Fascione is a Reader in Chemistry at the University of York, where he leads the Fascione Lab within the Department of Chemistry. His research focuses on the interface between chemistry and biology, particularly in the field of chemical glycobiology. He has established himself as a leading researcher in carbohydrate chemistry with expertise in synthetic methods and biological applications. Dr. Fascione received his Ph.D. from the University of Leeds in 2009 under the supervision of W. Bruce Turnbull, followed by a Marie Curie International Outgoing Fellowship at the University of British Columbia with Prof. Steve Withers and the University of York with Prof. Gideon Davies. Since August 2014, he has been at the York Structural Biology Laboratory, progressing from Lecturer to his current position as Reader. His research centers on complex sugars (glycans) and their roles in biological processes and disease, with particular emphasis on sialic acid-like molecules critical for bacterial pathogens. The Fascione group develops chemical tools to study and perturb glycan activity in vivo using synthetic and enzymatic carbohydrate chemistry, organocatalysis, enzymology, and molecular biology. Key research areas include pseudaminic acid biosynthesis, protein bioconjugation, and glycoconjugate development for therapeutic applications. Analysis of Dr. Fascione's recent publications reveals a strong focus on bacterial glycans, particularly pseudaminic acid, and their role in pathogenesis. His work combines synthetic chemistry with biological applications, developing novel methods for protein modification, carbohydrate synthesis, and glycan-based therapeutics. Major themes include bioorthogonal chemistry, enzymatic synthesis of complex carbohydrates, and the development of glycoconjugates for therapeutic and diagnostic applications. Dr. Fascione has received significant recognition for his work, including: Marie Curie International Outgoing Fellowship (2012-2014) ERC Consolidator Grant (2022) As an active researcher, Dr. Fascione supervises PhD students and collaborates extensively with researchers in the UK and internationally. His laboratory is involved in multiple research projects focused on chemical glycobiology for infectious disease research and therapeutic development. The Fascione Lab has established itself as a leading center for research at the chemistry-biology interface, with particular expertise in carbohydrate-active enzymes and glycan-based tools for biological investigation.

• Carbohydrate Chemistry
• Chemical Glycobiology
• Glycomedicine
• +۱۱ مورد دیگر

Professor David Thomas holds the position of Professor in Computer Engineering at the University of Southampton's Electronics and Computer Science Department. His research focuses on the intersection of software and hardware, particularly leveraging FPGAs for novel digital architectures and event-driven computing. He has a notable academic trajectory, having previously served as a Lecturer and Senior Lecturer at Imperial College London before joining Southampton in 2021. Dr. Thomas is actively involved in supervising PhD students and contributes to interdisciplinary research projects funded by the EPSRC, such as the SONNETS initiative exploring scalable event-triggered systems. Education: BSc in Computer Science (Imperial College London), PhD in Digital Architectures (Imperial College London). Postdoctoral roles included Research Associate and Research Fellow at Imperial's Department of Computing. Research Interests: Event-driven computing, FPGA-based systems, high-level synthesis, and high-performance computing. His work emphasizes practical implementations of theoretical models, such as custom processors and application-specific accelerators. Current projects include optimizing random number generation for FPGAs and exploring meta-programming techniques for hardware design. Advising and Grants: Supervises multiple PhD students in areas like neuromorphic computing and algorithm optimization. Active in securing funding for distributed system architectures and FPGA-based solutions. Labs/Teams: Member of the Cyber Physical Systems research group. Collaborates with interdisciplinary teams on projects like POETS (Partially Ordered Event-Triggered Systems) for large-scale parallel computing.

• Event-driven Computing
• FPGAs
• Digital Architectures
• +۳ مورد دیگر

Christos Tapeinos is a Lecturer in Pharmaceutical Sciences at the University of Manchester, specializing in pharmaceutical nanotechnology for treating brain diseases (e.g., glioblastoma, neuroinflammation) and pancreatic cancer. His research focuses on developing smart nanomedicines, advanced in vitro models (e.g., fluidic systems mimicking brain environments), and stimuli-responsive nanomaterials to overcome biological barriers like the blood-brain barrier. He leads the development of skin-mimicking models for subcutaneous drug delivery as a Co-Investigator in the HALo program. Education: Docent in Pharmaceutical Nanotechnology (2022) PhD in Materials Science (2013) MSc in Materials Science (2010) BSc in Materials Science (2006) Research Interests: Drug delivery systems, nanoparticle engineering, in vitro disease models, biomimetic materials, and translational nanomedicine. He integrates nanotechnology with precision medicine to address complex diseases. Recent Articles Trends: Focus on nanoparticle-cell interactions, phototherapy systems, graphene-cerium oxide hydrogels, and targeted theranostics. Highlights include ROS-scavenging systems and multi-stage nanovectors for CNS pathologies. Awards: Marie Skłodowska-Curie Actions Fellowship. Grants/Projects: Supported by EPSRC, The Royal Society, and Translation Manchester. Active in the Hub for Long-Acting Technologies (2024–2030). Labs/Teams: Leads research groups developing fluidic BBB models, skin-mimicking drug diffusion systems, and nanomaterial-based therapies.

• Pharmaceutical Nanotechnology
• Drug Delivery Systems
• Brain Diseases (Glioblastoma, Neuroinflammation)
• +۵ مورد دیگر

Dr. Youngchan Kim is a Lecturer in Quantum Biology at the University of Surrey , serving as Director of the Quantum Biology Doctoral Training Centre (QB-DTC). He is affiliated with multiple departments including the School of Biosciences, Advanced Technology Institute, and Quantum Sciences Group. PhD in Physics (2011), Korea Advanced Institute of Science and Technology MSc in Physics (2008), KAIST BSc in Physics (2006), Chung-Ang University Graduate Certificate in Learning and Teaching (2022), Advance HE His research focuses on quantum phenomena in biological systems at physiological temperatures, particularly using femtosecond optical spectroscopy and genetically engineered fluorescent proteins to explore evolutionary adaptations and develop quantum-bio-inspired technologies like room-temperature single-photon sources. The 15 most recent publications span quantum biology, biophotonics, and optical spectroscopy, with particular emphasis on quantum coherence in biological systems , terahertz birefringence , fluorescent protein dynamics , and biomedical imaging innovations . These works demonstrate his interdisciplinary approach bridging physics, biology, and medical applications. As QB-DTC Director, he leads transdisciplinary initiatives fostering collaboration between quantum physics and biosciences. His technical expertise includes time-correlated single-photon counting , common-path interferometry , and ultrafast fluorescence depolarization techniques.

• Quantum Biology
• Biophotonics
• Bioimaging
• +۳ مورد دیگر

Ramanujan Hegde serves as a Professor and Group Leader at the MRC Laboratory of Molecular Biology (LMB), University of Cambridge, where he directs research on membrane protein biosynthesis and cellular quality control mechanisms. His work examines how membrane proteins are accurately targeted to organelles, inserted into lipid bilayers, folded, and assembled into functional complexes, with emphasis on the cellular pathways that eliminate defective proteins to prevent disease. Professor Hegde's research program focuses on fundamental questions in cell biology: How do cells ensure precise membrane protein localization? What molecular machinery governs protein insertion and folding? How do quality control systems detect and degrade misfolded proteins? His investigations reveal that biosynthetic failures are common, triggering degradation pathways linked to diseases like neurodegeneration. Key research areas include: Intramembrane chaperone mechanisms for multipass membrane proteins Orphan subunit recognition during complex assembly Ribosome-associated mRNA degradation in autoregulation Proteasome assembly quality control ER membrane protein complex functions Molecular basis of protein aggregation diseases His 2017-2023 publications in Cell, Nature, and Science demonstrate consistent innovation in protein quality control, with landmark discoveries including UBE2O's role in orphan subunit degradation, the EMC as a transmembrane domain insertase, and TTC5-mediated tubulin autoregulation. These works bridge basic cell biology with disease mechanisms through rigorous biochemical and structural approaches. Professor Hegde mentors a research team of 11 scientists: Christine Desroches Altamirano Zhong Yan Gan Dino Janssen Ryan Judy Jennifer Miao Elizabeth Miller Tim Stevens Julia Toplak Huping Wang Haoxi Wu Eszter Zavodszky His laboratory operates within the MRC LMB's world-class infrastructure, utilizing advanced techniques in biochemistry, structural biology, and cell imaging. Supported by Medical Research Council funding, the group maintains strong collaborations across Cambridge and internationally to dissect protein biogenesis pathways with implications for therapeutic development in protein-misfolding disorders.

• Cell Biology
• Molecular Biology
• Membrane Proteins
• +۳ مورد دیگر

Professor Dario Alessi is a leading academic at the University of Dundee's School of Life Sciences, serving as the Director of the MRC Protein Phosphorylation Unit (MRC PPU) and Professor of Signal Transduction. He earned his BSc (1988) and PhD (1991) from the University of Birmingham. His research focuses on protein phosphorylation and ubiquitylation pathways, particularly the LRRK2 kinase pathway linked to Parkinson's disease. He has made groundbreaking contributions to understanding LRRK2's role in neurodegeneration, including its interaction with Rab proteins and scaffolding molecules like RILPL1. School of Life Sciences, University of Dundee MRC PPU Director since 2012 Signal Transduction Therapy Unit Director His work combines molecular biology, biochemistry, and collaborative industry partnerships to advance therapeutic strategies for Parkinson's disease. Key research areas include LRRK2 activation mechanisms, Rab protein phosphorylation, and lysosomal dysfunction. Alessi has trained over 30 graduate students and 40 postdocs, many now in academic and industry leadership roles. Notable awards include the EMBO Gold Medal (2005), the Robert A. Pritzker Prize for Leadership in Parkinson’s Research (2023), and an OBE (2023) for contributions to medical science. His lab promotes open science, sharing reagents and protocols globally through platforms like MRC Pure Agents and LRRK2.bio. Current projects include investigating novel mitochondrial and organelle biology in Parkinson’s, developing biomarkers, and advancing LRRK2 inhibitors through clinical trials. Collaborations span the Michael J. Fox Foundation, Aligning Science Across Parkinson’s, and the UK Dementia Research Initiative.

• Protein Phosphorylation
• Ubiquitylation Pathways
• Parkinson's Disease
• +۳ مورد دیگر

Dr. Martin Fascione is a Reader in Chemistry at the University of York. He leads research at the interface of chemistry and biology, focusing on chemical glycobiology and glycomedicine. His work employs synthetic chemistry, enzymology, and bioconjugation to study carbohydrate roles in disease and develop therapeutic tools. Research interests include the chemical glycobiology of nonulosonic/sialic acids, synthetic and enzymatic carbohydrate chemistry, and protein bioconjugation. His group investigates bacterial pathogen recognition, tumor metastasis, and immunological responses mediated by glycans. Recent publications demonstrate a focus on bacterial glycans, enzyme mechanisms, glycoconjugate therapeutics, and diagnostic tools. Trends include structural enzymology, chemoenzymatic synthesis, glycan-based sensors, and bioorthogonal chemistry applications. Awards: ERC Consolidator Grant (2022) Marie Curie International Outgoing Fellowship (2012-2014) Dr. Fascione directs an interdisciplinary lab collaborating with structural biologists and clinicians. His ERC grant supports research on pseudaminic acid sugars in infectious diseases.

• Chemical Glycobiology
• Synthetic Carbohydrate Chemistry
• Protein Bioconjugation
• +۳ مورد دیگر

Paula Mendes is a Professor of Advanced Materials and Nanotechnology at the University of Birmingham's School of Chemical Engineering. She leads the interdisciplinary Mendes Research Group, focusing on nanoscience, biosensors, and nanotechnology applications in healthcare. Her work bridges engineering, chemistry, and biology to address challenges in biofouling, molecular diagnostics, and medical technologies. She is affiliated with the Healthcare Technologies Institute (HTI), advancing translational research in regenerative medicine and diagnostics. Education: MSc (1997) and PhD (2002) in Chemical Engineering from the University of Porto. Postdoctoral research at the University of Birmingham and UCLA under Fraser Stoddart. Academic career at Birmingham since 2006, promoted to Professor in 2013. Research Interests: Development of electrically switchable surfaces for on-demand biosensing Nanomaterials for cancer diagnostics and molecular imprinting Anti-biofouling materials and nanoelectrocatalysts for fuel cells Integration of nanotechnology with biological systems Awards: ERC Advanced Grant (2024), IChemE Global Award (2016), Women in Tech Academic Award (2019), and over 100 published manuscripts. Advising & Grants: Supervises doctoral students in molecular diagnostics and biosensor development. Holds grants including EPSRC Leadership Fellowship and ERC Consolidator/Advanced Grants. Her group collaborates across disciplines to translate nanotechnology into clinical applications. Labs/Teams: Mendes Research Group at the University of Birmingham, part of the HTI network. Active in editorial roles for journals like Responsive Materials and ChemBioEng Reviews .

• Nanotechnology
• Materials Science
• Biomedical Engineering
• +۵ مورد دیگر

Dr. Lida Derevnina is a leading researcher in plant-pathogen interactions and immune receptor networks at the University of Cambridge , affiliated with the School of Biological Sciences and the Department of Plant Sciences . She heads the Crop Pathogen Immunity Group at the Crop Science Centre , focusing on NLR (Nucleotide-binding and Leucine-Rich Repeat) immune receptor networks and pathogen effector functions to engineer durable crop resistance. Education: PhD in Plant Pathology and Phytopathology, University of Sydney (2008-2012) BSc in Agricultural Science, University of Sydney (2004-2007) Her research explores how pathogens evade plant immunity through effector proteins and how NLR networks can be bioengineered to counteract these mechanisms. This work bridges molecular biology, evolutionary genetics, and sustainable agriculture, with recent advances in resistosome activation models and effectorome characterization. Scientific awards include the Crop Science Centre Fellowship (2022) , Marie Skłodowska-Curie Individual Fellowship (2016) , and the Jeanie Borlaug Laube Women in Triticum Award (2012) . Her work has been published in top journals such as Science , Nature , and PLoS Biology . Dr. Derevnina is actively engaged in public outreach, including the Talking Biotech podcast and a YouTube video explaining plant immunity . Her laboratory collaborates on projects related to global food security and pathogen genomics.

• Plant Pathology
• Plant Immunity
• Molecular Plant Pathology
• +۳ مورد دیگر