Melody Alsaker is an Associate Professor in the Department of Mathematics at Gonzaga University, where she has held this position since January 2016. Her research focuses on medical imaging and applied inverse problems, particularly in the field of electrical impedance tomography (EIT). She specializes in mathematical modeling, algorithm design, and biomedical image processing, with applications in pulmonary and thoracic imaging. Her work emphasizes improving EIT reconstruction techniques using the D-bar method, incorporating spatial priors, and developing real-time solutions for clinical applications. Notable contributions include the ACE1 EIT system for thoracic imaging and studies on stroke classification, air trapping in lungs, and surrogate measures of pulmonary function in children with cystic fibrosis. Alsaker's research bridges mathematics and engineering, addressing challenges in medical imaging accuracy and computational efficiency. Her collaborations span disciplines, including biomedical engineering, respiratory physiology, and clinical medicine.
Dr. Yunjie Yang is an Associate Professor at the University of Edinburgh's School of Engineering, with affiliations at the Edinburgh Futures Institute (EFI), the Edinburgh Generative AI Laboratory (GAIL), and the Edinburgh Centre for Robotics. He previously held the Chancellor's Fellow in Data Driven Innovation (2018-2023) and Bayes Innovation Fellow (2023-2024) positions. His research focuses on AI-powered sensing and imaging, machine learning, and soft sensors & electronics for robotics. Yang received his PhD in Engineering Electronics from the University of Edinburgh, MSc in Control Science & Engineering from Tsinghua University, and BEng in Measurement & Control Engineering from Anhui University. After his PhD, he worked as a Postdoctoral Research Associate in Chemical Species Tomography before securing his lectureship. His research interests center on developing intelligent sensing systems that replicate human perception capabilities for robotics and intelligent systems. He pioneers flexible sensing and imaging technologies across various scales through innovative multi-modal sensors, soft electronics, and their modeling using machine learning approaches. His work aims to enable autonomous physical artificial intelligence by bridging the gap between robotic systems and human-like perception. Analysis of his recent publications reveals a strong focus on soft robotics perception, particularly through electrical impedance tomography (EIT) and transformer-based architectures. His research spans medical imaging applications, digital twin modeling for industrial processes, and machine learning approaches for sensor data interpretation. The trend shows increasing integration of physics-informed deep learning with traditional tomographic techniques to achieve higher accuracy and efficiency. European Research Council (ERC) Starting Grant (2024) IEEE J. Barry Oakes Advancement Award (2024) IEEE I&M Society Graduate Fellowship Award (2015) Multiple Best Paper Awards Senior Member of IEEE Fellow of the International Society for Industrial Process Tomography Fellow of the Higher Education Academy ESI highly cited papers Dr. Yang serves as Associate Editor for IEEE Transactions on Instrumentation and Measurement and holds editorial positions with Scientific Reports and IEEE Sensors Journal. His research has been licensed to overseas research institutes and industry partners and received wide media coverage including BBC, EFE, USA Today, and STV. He has secured significant grant funding including the prestigious ERC Starting Grant. He leads the Edinburgh SMART Lab (Sensing/imaging + Machine Learning + Robotics), which aims to replicate human perception capabilities for robotics and advance flexible sensing technologies through innovative multi-modal sensors and machine learning approaches. The lab focuses on enabling autonomous physical artificial intelligence with applications spanning medical diagnostics, industrial monitoring, and advanced robotics systems.
Holger Fröning is a full professor at Heidelberg University’s Institute of Computer Engineering (ZITI), where he leads the Hardware and Artificial Intelligence (HAWAII) Lab. His research focuses on embedded machine learning , high-performance computing , and hardware-software co-design , with emphasis on resource efficiency, power optimization, and emerging architectures like analog , photonic , and resistive memory systems. He has held leadership roles including Managing Director of ZITI (2023–present) and Dean of Studies for Computer Science (2019–2022) , and has collaborated with institutions such as NVIDIA Research, Chinese Academy of Sciences, and Graz University of Technology. Research Trends : His recent publications explore Bayesian neural networks , green machine learning , analog computing noise mitigation , and GPU/FPGA optimization . Articles highlight photonic computing for AI , memory-efficient training , and hardware-aware DNN compression . Scientific Awards : 2025 HiPEAC Paper Award (Nature Computational Science) 2014 Google Faculty Research Award Multiple Best Paper Awards (IPDPS, ICPP, ECML-PKDD workshops) Leadership & Service : Organized workshops (WEML, ITEM, F4HD), chaired tracks at EuroPar and ISC, and served on program committees for ICPR, ECAI, and FPL. Education & Affiliations : PhD and MSc from University of Mannheim (2007/2001). Sponsors include DFG, FWF, FFG, NVIDIA, SAP, and XILINX.
Univ-Prof. Dr. med. Malek Bajbouj serves as Director of the Institute for Affective Neuroscience and Emotion Modulation at Charité – University Medicine Berlin's Campus Benjamin Franklin (CBF), operating within the Department of Neurology, Neurosurgery and Psychiatry (CC 15). His position integrates clinical leadership with translational neuroscience research focused on severe mental illnesses. Dr. Bajbouj's research program centers on affective neuroscience and emotion dysregulation mechanisms in psychiatric disorders, particularly schizophrenia spectrum conditions and depression. He pioneers multimodal intervention approaches combining neuromodulation (tDCS), oxytocin augmentation, mindfulness therapies, and digital health tools. His work emphasizes translational biomarker development using neuroimaging, machine learning, and physiological stress parameter analysis to personalize treatment for treatment-resistant populations. Analysis of his 2023-2025 publications reveals three dominant research trajectories: (1) novel treatment combinations for negative symptoms in schizophrenia (oxytocin + mindfulness, yoga therapy); (2) real-world implementation of neuromodulation (at-home tDCS protocols, technical efficacy monitoring); and (3) global mental health responses to crises (pandemic impacts on vulnerable groups, culturally adapted refugee interventions). His methodology consistently employs rigorous randomized controlled trials with embedded biomarker studies. As director of his eponymous institute, Dr. Bajbouj leads a multidisciplinary team conducting neuroimaging studies, clinical trials, and international collaborations focused on emotion modulation pathways. The institute coordinates research across CC 15's clinical infrastructure at CBF Building V, with particular emphasis on bridging laboratory neuroscience with clinical psychiatry through the DepressionDC and OXYMIND trial frameworks.
Dr. Yayun Du is an Assistant Professor in the Department of Electrical and Computer Engineering at Vanderbilt University School of Engineering. She holds a Ph.D. in Robotics and System Control (Minor: Solid Mechanics) from UCLA (2022) and was a postdoctoral scholar at Northwestern University's Rogers Group through 2024. Current faculty at Vanderbilt University Ph.D. from University of California, Los Angeles Postdoctoral experience at Northwestern University Her research integrates bioelectronics and robotics through three core directions: 1) Developing multimodal wearable/implantable sensors for health monitoring, 2) Creating human-in-the-loop interaction systems using brain-computer interfaces, and 3) Applying machine learning to medical environment robotics. She has deployed four sensor types across seven hospitals globally, serving users from neonates to elderly patients. Dr. Du's recent publications focus on wireless bioelectronic devices ( PNAS ), sustainable sensor materials ( ACS Sustainable Chemistry & Engineering ), and agricultural robotics ( ICRA , IROS ). She serves as Associate Editor for ICRA 2025 and has received two Best Paper Award final nominations at IROS 2021. Finalist - Best Paper Award in Agri-Robotics (IROS 2021) Finalist - Best Paper Award in Robot Mechanisms and Design (IROS 2021) As head of the Du Group, she leads interdisciplinary research with applications in both healthcare and agricultural contexts, collaborating with Vanderbilt Institute for Surgery and Engineering (VISE) and clinical partners. Her work emphasizes deployable systems that transition from academic research to real-world implementation in medical and industrial environments.
Jianming Liang is a full professor at Arizona State University's College of Health Solutions, specializing in biomedical informatics, data science, and computer vision. His research focuses on self-supervised learning, foundation models, and improving transfer learning techniques for medical imaging applications. National Academy of Inventors Fellow (2021) ASU Faculty Innovation Award (2019) ASU Distinguished Faculty Award (2023) NIH R01 grant recipient Led lab producing FDA-approved medical imaging products His lab has developed multiple open-source frameworks like Ark , Foundation_X , and ModelsGenesis for medical image analysis. Team has received over 70 student research awards including NCWIT Collegiate and AMIA Ph.D. Dissertation honors. Key research contributions include: Anatomically consistent foundation models Domain-adaptive pretraining strategies Annotation-efficient deep learning Integrated classification/localization/segmentation frameworks 40+ US patents (50+ pending) Major publications demonstrate leadership in self-supervised learning for chest radiography, pulmonary embolism detection, and medical AI explainability.
Clark Olson is a Professor in the Division of Computing & Software Systems at the University of Washington Bothell, part of the School of Science, Technology, Engineering & Mathematics. He earned his Ph.D. in Computer Science from UC Berkeley (1994), M.S. in Electrical Engineering (1990), and B.S. in Computer Engineering (1989) from the University of Washington, Seattle. Education: Ph.D. in Computer Science (2017) from University of California, Berkeley M.S. in Electrical Engineering (1990) from University of Washington, Seattle B.S. in Computer Engineering (1989) from University of Washington, Seattle His research focuses on computer vision, robot navigation, and clustering algorithms. He has developed techniques for Mars rover terrain mapping, subspace clustering, and geometric feature matching. His work bridges theory and application in autonomous systems and image analysis. Analysis of his publications reveals expertise in computer vision (8 papers), clustering algorithms (4 papers), and robotics (5 papers). Key subtopics include Mars exploration (3 papers), Hough transforms (3 papers), and probabilistic methods (3 papers). Professor Olson teaches courses ranging from introductory programming (CSS 161-162) to advanced topics in computer vision (CSS 487-587) and algorithm design (CSS 549). He also advises on the CSSE Capstone (CSS 497) projects requiring rigorous prerequisites and structured evaluation criteria.
Matthew B. Blaschko is a Professor in the Department of Electrical Engineering at KU Leuven, Belgium. He serves as director of the KU Leuven ELLIS unit and is a fellow in the ELLIS Health program. He is a Core PI in the Flanders AI Research Program, working as a workpackage lead for Decision Support Systems and Medical Imaging. Blaschko is also a member of the KU Leuven Institute for Artificial Intelligence and one of the leaders of the working group on Machine Learning and Data Science. Professor Blaschko received his B.S. from Columbia University, M.S. from the University of Massachusetts Amherst, and Dr. rer. nat. from Technische Universität Berlin (awarded for work at Max Planck Institutes Tübingen). He was a Newton International Fellow at the University of Oxford and received his Habilitation (HDR) from École Normale Supérieure de Cachan. Prior to joining KU Leuven, he was a Permanent Research Scientist in the INRIA Saclay Research Center and a Faculty Member at Ecole Centrale Paris. His research focuses on machine learning techniques applied to visual data, with particular emphasis on calibration in deep learning, medical image analysis, and federated learning. Blaschko's work bridges theoretical foundations with practical applications, as evidenced by technology developed in his research being incorporated into MONA, software for ophthalmic image analysis. His research group has made significant contributions to the fields of model calibration, uncertainty estimation, and medical imaging analysis, with recent publications showing strong trends toward improving reliability of AI systems in medical contexts and advancing theoretical understanding of calibration metrics. Professor Blaschko has been recognized with several awards including the Université Paris-Saclay STIC Doctoral School Best Scientific Contribution Award, Best Paper Award at CVPR 2008, Main Award at DAGM 2008, and Best Student Paper Award at ECCV 2008. Professor Blaschko has supervised numerous PhD and Master's students, with current and former students including Deniz Soysal, Claire Marchal, Dongli Xu, Sebastian Gruber, Jiameng Li, Marco Mezzina, and many others working on diverse topics from Alzheimer's disease analysis to surgical phase recognition. His research has been supported by various funding sources including the Flanders AI Research Program. He has co-organized several influential workshops including the "Another Brick in the AI Wall: Building Practical Solutions from Theoretical Foundations" at CVPR 2025, Commands 4 Autonomous Vehicles workshop at ECCV 2020, and the Learning from Limited Labeled Data workshop series at NIPS 2017 and ICLR 2019. His laboratory focuses on machine learning for medical image analysis, with applications in ophthalmology, neurology, and surgical robotics. The group maintains active collaborations with medical institutions and participates in international challenges such as the KNee OsteoArthritis Prediction (KNOAP2020) challenge.
Devis Tuia serves as Associate Professor at the Swiss Federal Institute of Technology Lausanne (EPFL), holding appointments in the Institute of Environmental Engineering (IIE) within the School of Architecture, Civil and Environmental Engineering (ENAC). He leads the Environmental Computational Science and Earth Observation Laboratory (ECEO) since 2020 and contributes to EPFL's Doctoral Program in Civil and Environmental Engineering. His academic journey began in Lausanne with studies at UNIL and EPFL, culminating in a PhD in remote sensing from UNIL. Postdoctoral research followed at institutions in Valencia, Boulder, and EPFL, focusing on machine learning model adaptation. He progressed from Research Assistant Professor at University of Zurich to Associate and Full Professor at Wageningen University before joining EPFL. Tuia's research bridges Earth observation with artificial intelligence, specializing in interpretable deep learning for environmental applications. His lab develops algorithms for making remote sensing accessible, with particular emphasis on digital wildlife conservation through automated censuses using drone and satellite imagery. Current projects tackle the 'black box' problem in environmental modeling while advancing spatial intelligence for sustainable urban development. His 2023-2025 publication portfolio reveals three dominant trends: (1) species distribution modeling using incomplete observations, (2) multimodal fusion of satellite/drone data with textual descriptions, and (3) interpretable AI frameworks for environmental decision-making. This work consistently addresses real-world challenges like wildfire forecasting and biodiversity monitoring. As an educator, Tuia supervises 12 current PhD students and has graduated 4 former EPFL doctoral candidates. His teaching portfolio includes Frontiers of Deep Learning for Engineers , Sensing and Spatial Modeling for Earth Observation , and Image Processing for Earth Observation courses. The ECEO laboratory maintains active collaborations with ESA-NASA initiatives and conservation organizations globally.
Qingguo Li is a Professor and Associate Head at the Department of Mechanical and Materials Engineering , Queen's University , and a member of the Ingenuity Labs Research Institute . He specializes in biomechanical system design, energy harvesting, wearable sensors, gait analysis, and load carriage systems. His research integrates robotics, biomedical engineering, and sensor technology to develop human-centric devices and mobility aids. Current Roles : Professor, Associate Head, Queen's University Research Institute : Ingenuity Labs Research Institute Lab : Bio-Mechatronics and Robotics Laboratory His work focuses on biomechanical energy harvesting , IMU-based motion analysis , and assistive device development . Key applications include stroke rehabilitation, gait monitoring, and wearable power generation systems. Articles span cable-driven robots , smart walkers , and 3D printing mechanisms , emphasizing human-robot interaction and dynamic modeling . The lab explores sensor calibration , adaptive control algorithms , and human movement optimization . Areas of impact include rehabilitation engineering , load carriage stability , wearable sensor accuracy , and assistive robotics . His team develops solutions for gait asymmetry detection , post-stroke mobility , and low-cost energy systems , leveraging machine learning and kinetic modeling .
Professor Amin Abbosh is a faculty member at the School of Electrical Engineering and Computer Science, University of Queensland. His research focuses on Medical Microwave Imaging and Millimeter-wave Engineering, with contributions to advanced imaging systems, antenna design, and communication technologies. He leads projects in electromagnetic medical sensing, including portable brain scanners and wearable diagnostic systems. His work integrates applied electromagnetics with AI-driven algorithms, addressing challenges in stroke detection, liver health monitoring, and deep vein thrombosis diagnosis. With over 16 patents and collaborations across biomedical and engineering domains, his research bridges clinical needs with cutting-edge electromagnetic techniques. Key projects include the development of low-cost healthcare monitoring systems and reconfigurable antennas for satellite communications. Research interests span medical imaging systems, antenna array design, and signal processing for healthcare applications. His team innovates in areas like phased arrays, dielectric property analysis, and non-invasive diagnostics. Recent advancements include synthetic microwave focusing techniques and self-supervised deep learning models for clutter removal in imaging. Publications highlight contributions in IEEE journals and conferences, emphasizing clinical applications and device prototyping. Collaborations with institutions like the University of Queensland’s medical faculty and industry partners ensure practical implementation of his research.
Hiroshi Ishikawa is a Professor in the Department of Computer Science and Engineering at Waseda University's Faculty of Science and Engineering. He also serves as a Visiting Professor at the National Institute of Informatics since 2016. Previously, he held positions at Nagoya City University from 2004-2010 as Assistant Professor, Associate Professor, and Professor. His academic journey includes being a JST PRESTO Researcher from 2009-2013 and an Associate Research Scientist at New York University's Courant Institute of Mathematical Sciences from 2000-2001. Ph.D. in Computer Science, New York University (2000) Master of Science, Kyoto University Bachelor's degree in Mathematics, Kyoto University Faculty of Science (1991) Hiroshi Ishikawa's research spans perceptual information processing, computer vision, artificial intelligence, deep learning, and discrete optimization. His work focuses on developing algorithms for image restoration, segmentation, and understanding, with significant contributions to energy minimization techniques in computer vision. He has pioneered approaches in sketch simplification, medical image segmentation, and higher-order graph cuts. His research bridges theoretical advances in mathematical optimization with practical applications in medical imaging, computer graphics, and consumer electronics. Ishikawa's recent publications demonstrate a strong focus on leveraging deep learning for image enhancement and understanding. His work spans super-resolution techniques, colorization methods, human avatar generation, and medical image analysis. A notable trend is the increasing integration of attention mechanisms and generative models to solve complex vision problems, with growing emphasis on real-world applications in medical imaging and computer graphics. His research group consistently produces high-impact work that appears in top-tier computer vision conferences. 75th Annual IEICE Best Paper Award (2019) Innovative Technologies 2016 Special Prize for Culture (Ministry of Economy, Trade and Industry) MIRU Nagao Award (Best Paper Award) (2009) Young Author Award (IEEE Computer Society Japan Chapter, 2006) MIRU2006 Excellent Paper Award (2006) Harold Grad Memorial Prize (Courant Institute of Mathematical Sciences, NYU, 2000) As a professor at Waseda University, Ishikawa has mentored numerous students who have become active researchers in computer vision, including Yuya Masuda, Edgar Simo-Serra, and Satoshi Iizuka. His research has been supported by various grants, including JST PRESTO funding from 2009-2013. He has served on editorial boards for prestigious journals including IEEE Transactions on Pattern Analysis and Machine Intelligence and has held leadership roles in major computer vision conferences such as ICCV, CVPR, and ACCV. Ishikawa leads a vibrant research group at Waseda University focused on computer vision and image processing. His laboratory collaborates extensively with researchers at Nagoya City University, National Institute of Informatics, and international institutions. The group maintains strong connections with industry partners, particularly in medical imaging and consumer electronics sectors, translating theoretical advances into practical applications.
Benyuan Liu is a Professor at the Miner School of Computer and Information Sciences within the Kennedy College of Sciences at the University of Massachusetts Lowell . He serves as Director and Graduate Coordinator for Ph.D. programs, with expertise in Data and Computer Communication Networks, Mobile and Wireless Networks, and Internet Technologies & Applications. Education: B.S., University of Science and Technology of China M.S., Yale University Ph.D., University of Massachusetts Amherst His research focuses on Artificial Intelligence in Medical Imaging , Deep Learning for Endoscopy , and Edge Computing Systems . Recent work includes automated lesion detection, 3D reconstruction from sensor data, and predictive models for financial and reproductive health domains. The 15 most recent publications highlight applications of deep learning in medical diagnostics (thyroid nodules, gastric lesions, dental caries), computer vision (attention mechanisms, transformers), and financial technology (market psychology analysis). Technical themes include mmwave radar processing, diffusion models for synthetic data, and multi-scale feature extraction. Benyuan Liu leads the Computer Networking Lab and CHORDS initiative at UMass Center for Digital Health. His work bridges network optimization with healthcare AI , emphasizing real-time systems and portable diagnostics.
Pengtao Xie is an Associate Professor (with tenure as of June 2025) in the Department of Electrical and Computer Engineering at the University of California San Diego. He also serves as Associate Adjunct Professor in the Division of Biomedical Informatics, Department of Medicine, and holds affiliate appointments with the Halıcıoğlu Data Science Institute, School of Biological Sciences, Shu Chien-Gene Lay Department of Bioengineering, Skaggs School of Pharmacy and Pharmaceutical Sciences, and multiple research institutes including the AI Group, Center for Machine-Intelligence, Computing and Security, Institute of Engineering in Medicine, and Institute for Genomic Medicine. Education: PhD in Machine Learning, School of Computer Science, Carnegie Mellon University Research Interests: His research focuses on machine learning inspired by human learning skills, such as self-explanation, small-group learning, and learning by teaching. He applies these techniques to large language models, foundation models, healthcare, and biomedicine. His work spans generative AI, medical imaging, protein modeling, and drug discovery. Recent Research Trends: His 2024–2025 publications emphasize generative AI for ultra-low-data medical image segmentation, multimodal large language models for biomedical applications, protein function prediction, and novel training strategies like task-adaptive pretraining and bi-level optimization for model adaptation. Scientific Awards: NIH MIRA Award (2025) NSF CAREER Award (2024) Best Graduate Teacher Award – UCSD ECE (2023) ICLR Notable-Top-5% Paper (2023) Global Top-100 Chinese Young Scholars in AI (2022) UCSD Faculty Career Development Award (2022) Tencent Faculty Award (2021) Outstanding Reviewer – ICLR (2021) AMIA Doctoral Dissertation Award Finalist (2020) Amazon AWS Research Award (2020) Tencent AI-Lab Faculty Award (2020) Innovator Award – Pittsburgh Business Times (2018) Siebel Scholarship (2014) Advising and Grants: He currently advises PhD students, postdocs, and master’s students. He has received major grants including the NIH MIRA and NSF CAREER awards, and actively mentors Schmidt AI in Science postdocs and graduate students. Teaching and Labs: He teaches ECE285 Deep Generative Models and ECE175B Probabilistic Reasoning and Graphical Models . His lab focuses on foundational and translational AI research with applications in biomedicine and healthcare.
Vladimir Spokoiny is a Professor at the Departments of Mathematics and Economics of the Humboldt University of Berlin and Head of the Research Group "Stochastic Algorithms and Nonparametric Statistics" at the Weierstrass Institute for Applied Analysis and Stochastics (WIAS) in Berlin, Germany. His research spans multiple areas of statistics, machine learning, and financial mathematics, with significant contributions to nonparametric statistics, high-dimensional data analysis, and statistical methods in finance. Spokoiny received his M.Sc. in applied mathematics from the Moscow Institute of Railway Engineering in 1981 and his Ph.D. in mathematics from Lomonosov Moscow State University in 1988. He completed his Habilitation at Humboldt University in 1996. His academic career includes positions at the All-Union Institute of Railway Transport in Moscow, the Institute for Information Transmission Problems in Moscow, and the Institute for Applied Analysis and Statistics in Berlin before joining the Weierstrass Institute and Humboldt University where he has been a professor since 2002. Spokoiny's research focuses on adaptive nonparametric smoothing and hypothesis testing, high dimensional data analysis, statistical methods in finance, image analysis with applications to medicine, classification, and nonlinear time series. His work often addresses the challenges of nonstationarity in time series data and develops innovative methods for volatility estimation and risk management. He has made significant contributions to the development of adaptive weights smoothing procedures, which have applications in image processing, community detection, and manifold learning. His recent work has expanded into high-dimensional statistics, Bayesian inference, and optimization methods for machine learning, with publications demonstrating novel approaches to Gaussian approximation, Laplace methods, and statistical inference in non-Euclidean spaces. Spokoiny has supervised numerous PhD students including Oliver Reiss, Danilo Mercurio, Ying Chen, Elmar Diederichs, and Mstislav Elagin, whose research has focused on mathematical finance, time series analysis, and statistical methods. He serves as an Associate Editor for The Annals of Statistics (since 2004) and Statistics and Decisions (since 2002), and has previously served on the editorial board of the Journal of Statistical Planning and Inference. His professional activities include reviewing for major statistical journals including Annals of Statistics, Bernoulli, Econometrica, and Journal of American Statistical Association, as well as reviewing grant proposals for the National Science Foundation (USA), German Research Foundation, and Netherlands Organisation for Scientific Research. Spokoiny is a member of several professional societies including the International Statistical Institute, American Statistical Association, Institute of Mathematical Statistics, and Bernoulli Society. He is fluent in Russian (mother tongue), English, and German, and has good knowledge of French. His research group at WIAS focuses on developing novel statistical methodologies with applications across various scientific domains, particularly emphasizing adaptivity and robustness in complex data environments. The group's work has significant implications for financial risk management, medical imaging, and machine learning applications, with recent publications addressing fundamental questions in high-dimensional statistics and nonparametric inference.