Jennifer K. Mulligan is an Associate Professor in the Department of Otolaryngology – Head & Neck Surgery at the University of Florida. She holds multiple leadership roles including Vice Chair for Research, Co-Director of the UF Health Smell Disorders Program, and Director of Resident Research Education. Her academic work focuses on the immunopathogenesis of chronic rhinosinusitis (CRS) and olfactory dysfunction, with a particular interest in vitamin D metabolism, complement system regulation, and epithelial cell biology. Her research employs experimental models and clinical studies to investigate mechanisms underlying sinonasal inflammation and olfactory impairment. Notable contributions include elucidating roles of vitamin D3 in modulating immune responses and epithelial function, and developing biomarker-based endotyping strategies for CRS subtypes. She has pioneered nasal mucus proteomics and olfactory cleft analysis to identify novel therapeutic targets. Dr. Mulligan's grant portfolio includes NIH-funded projects on vitamin D modulation of CRS inflammation, immune responses to SARS-CoV-2 in upper airways, and biologic therapies for nasal polyposis. She leads clinical trials evaluating treatments like dupilumab for smell recovery. Over 100 peer-reviewed publications span immunology, otolaryngology, and translational research methodologies. Her teaching activities include instructing the GMS6847 course on translational research principles. She mentors residents and fellows in surgical research through structured educational programs. Active collaborations involve immunologists, bioengineers, and clinical researchers across multiple institutions.








