جست‌وجوی استاد و پژوهشگر

• Cancer Epidemiology
• Lifestyle Epidemiology
• Mendelian Randomization
• +۳ مورد دیگر

Susanna Larsson is an Associate Professor at Uppsala University's Faculty of Medicine within the Department of Surgical Sciences, specializing in Medical Epidemiology. She maintains dual appointments across university units, with primary research operations at Epihubben (Dag Hammarskjölds väg 14 B) and administrative ties to Akademiska sjukhuset. Her research spans cancer epidemiology , lifestyle factors , and Mendelian randomization methodologies , with particular focus on dietary impacts on chronic diseases. Recent work examines sleep patterns, meat consumption, and water contaminants through population-based cohorts and genetic analyses. Her publications consistently integrate Swedish cohort data with multinational collaborations to investigate cardiovascular diseases, inflammatory bowel conditions, and cancer etiology. Analysis of her 15 most recent publications reveals dominant trends in nutritional epidemiology (47% of articles), genetic risk assessment (33%), and environmental exposures (20%). Key methodological approaches include Mendelian randomization (60%), cohort studies (27%), and proteomic analyses (13%). Thematic clusters center on diet-disease relationships, cardiovascular-metabolic pathways, and gastrointestinal disorder mechanisms. Laboratory operations are centered at Epihubben, Uppsala's epidemiology hub, where she leads analyses of population-level Swedish health data. Her work frequently utilizes nationwide registries and biobanks, including collaborations with Akademiska sjukhuset for clinical data integration.

• Metabolism
• Cardiovascular Disease
• Non-alcoholic Fatty Liver Disease
• +۵ مورد دیگر

Dawei Zhang is a Professor in the Department of Pediatrics within the Faculty of Medicine & Dentistry at the University of Alberta. His laboratory focuses on metabolic pathways linked to human diseases, with particular emphasis on atherosclerotic cardiovascular disease, non-alcoholic fatty liver disease, and inflammatory arthritis. Current research centers on three primary areas: PCSK9-promoted LDLR degradation, membrane type-1 matrix metalloproteinase (MT1-MMP) in metabolism, and Surf4 protein functions in lipid metabolism. Dr. Zhang's research spans molecular mechanisms of lipid homeostasis and protein degradation pathways. His lab investigates how Surf4 regulates lipoprotein secretion and intestinal lipid absorption, how MT1-MMP influences extracellular matrix remodeling in arthritis, and how novel hormones like Cholesin bridge intestinal and hepatic cholesterol metabolism. Recent work demonstrates Surf4's critical role in VLDL secretion, LDLR degradation, and liver fibrosis pathways. As an educator, Dr. Zhang teaches Physiology 455/555 (Physiology of Lipids and Lipoproteins) and leads PAED 600 - Critical Discussions of Biomedical and Clinical Research. This graduate course employs discovery learning to critically evaluate literature in maternal and child health research, restricted to Pediatrics graduate students. Dr. Zhang maintains an active research program through the Zhang Lab (https://sites.google.com/ualberta.ca/zhang-lab/), with recent publications spanning molecular cardiology, hepatology, and matrix biology. His work demonstrates translational potential for novel therapeutics targeting metabolic disorders, with consistent high-impact publications in journals including Nature Communications, Journal of Lipid Research, and Matrix Biology.

Michael Plougمشاهده پروفایل

استاد

• Lipoprotein Metabolism
• Triglyceride Metabolism
• Cardiovascular Biology
• +۳ مورد دیگر

Michael Ploug is a Professor and Group Leader at the Biotech Research & Innovation Centre (BRIC), part of the Faculty of Health and Medical Sciences at the University of Copenhagen. His research program focuses on molecular mechanisms of lipoprotein metabolism and cardiovascular biology, with significant contributions to understanding triglyceride regulation and related disorders. Dr. Ploug's primary research interests include: Lipoprotein metabolism, particularly lipoprotein lipase (LPL) function and regulation Triglyceride metabolism and associated disorders Molecular mechanisms underlying cardiovascular diseases Cancer biology, with recent work on pancreatic cancer therapeutics Protein structure-function relationships in metabolic regulation Analysis of Dr. Ploug's recent publications reveals a consistent focus on lipoprotein metabolism mechanisms, particularly the role of lipoprotein lipase in triglyceride homeostasis. His work spans from fundamental molecular mechanisms to translational applications, with significant contributions to understanding APOA5 function and developing therapeutic approaches for metabolic disorders. His research demonstrates strong international collaboration across multiple countries. Dr. Ploug's research impact is evidenced by: Pickup by 6 news outlets 1 blog mention 16 posts by X users Reference in 1 patent 2 mentions by Bluesky users 26 readers on Mendeley As Group Leader of the Ploug Group at BRIC, he maintains an active laboratory with significant external collaborations. His research program bridges basic science with potential clinical applications in metabolic and cardiovascular diseases.

Clare Louise Hawkinsمشاهده پروفایل

استاد

• Atherosclerosis
• Oxidative stress
• Inflammation
• +۱۱ مورد دیگر

Clare Louise Hawkins is a Professor in the Department of Biomedical Sciences within the Faculty of Health and Medical Sciences at the University of Copenhagen. She joined the department in March 2017 after nearly 20 years at the Heart Research Institute in Sydney, where she served as Scientific Director and Inflammation Group Leader. Her research focuses on understanding the role of oxidative stress and inflammation in driving lesion development in atherosclerosis and related chronic inflammatory diseases. BSc(Hons) Chemistry, University of York, UK (1993) PhD Chemistry, University of York, UK (1997) Professor Hawkins' research investigates how oxidants produced during inflammation modify biological molecules and cells associated with the arterial wall, with particular focus on immune cell extracellular traps and myeloperoxidase-derived oxidants. Her work spans multiple disciplines including redox biology, cardiovascular disease, diabetes complications, and innate immunity. The Hawkins Group employs in vitro immune and vascular cell models, biochemical and cellular assays, molecular biology techniques, and analytical methodologies including HPLC and EPR spectroscopy to study these complex interactions. Her recent publications reveal consistent themes across redox biology, inflammation, and vascular disease, with particular emphasis on hypohalous acids, histone modifications, extracellular traps, and nucleic acid oxidation. These studies collectively aim to develop targeted therapies that limit damaging reactions during chronic inflammation without compromising innate immune defenses. 2018: Lifetime Achievement Award and Lecture, Society for Free Radical Research (Australasia) 2018: Leopold Flohe Redox Pioneer Award and Lecture, Society for Free Radical Research (Europe) 2016: Blackmore's Mentor of the Year Award, HRI 2013-16: Australian Research Council Future Fellowship 2009-12: Career Development Fellowship, National Heart Foundation, Australia 2003-8: R. Douglas Wright Biomedical Fellowship, National Health and Medical Research Council, Australia Professor Hawkins has mentored more than 30 PhD students to completion and serves as a mentor for postdocs and assistant professors both at UCPH and internationally. Her research is supported by significant grants including funding from the Independent Research Fund Denmark, Royal Society of Chemistry, and Novo Nordisk Foundation. As Secretary-General of the Society for Free Radical Research (Europe) since 2021, she maintains extensive international collaborations across multiple continents. The Hawkins Group (Redox Biology Group) focuses on gaining detailed understanding of how inflammatory oxidants and extracellular traps contribute to disease development. The team actively investigates four main research projects: protective mechanisms of selenocyanate in inflammatory disease, post-translational histone modification in inflammation, macrophage extracellular traps in disease, and nucleic acid modification in diabetes and inflammatory disease.

• Exercise Physiology
• Sports Medicine
• Nutrition
• +۳ مورد دیگر

Kenneth Hudlebusch Mertz serves as a Guest Researcher at the Department of Nutrition, Exercise and Sports, University of Copenhagen, focusing on the physiological and sociological dimensions of human performance and aging across diverse populations including elite athletes and retirees. His research spans Exercise Physiology , Sports Medicine , and Nutrition , with particular emphasis on skeletal muscle adaptation mechanisms, cardio-pulmonary responses to viral infections, and retirement lifestyle patterns. Key investigations include sex-specific training adaptations in elderly cohorts, SARS-CoV-2 impacts on athletic performance, and protein metabolism in aging populations, employing methodologies from clinical trials to sociological surveys. Analysis of his 2020-2023 publications reveals converging trends in translational human physiology research, integrating molecular biology with public health outcomes. His work consistently examines environmental stressors (viral infections, nutritional deficits, aging) on physical resilience, with notable contributions to understanding athlete health post-COVID-19 and retirement-time management in Danish society. No scientific awards were documented in the provided materials. While specific student mentorship or grant details remain unspecified, his collaborative projects—including the multi-institutional COVA study—demonstrate active engagement with clinical researchers and public health teams across Denmark. Mertz contributes to several high-impact research collectives, most prominently the COVA study group analyzing cardio-pulmonary sequelae in elite athletes, and collaborates extensively with University of Copenhagen teams on muscle physiology, aging interventions, and retirement sociology projects.

• Macrophage phenotypes
• Atherogenesis
• Uremia
• +۵ مورد دیگر

Line Bisgaard serves as a Teaching Assistant Professor and Guest Researcher in the Department of Biomedical Sciences at the University of Copenhagen's Faculty of Health and Medical Sciences. Her academic work spans both teaching responsibilities and active research in cardiovascular and kidney disease mechanisms, with particular focus on macrophage phenotypes in atherosclerotic plaques and the relationship between kidney disease and accelerated atherosclerosis. M.Sc., Molecular Biomedicine, University of Copenhagen (2010) Dr. Bisgaard's research program centers on two primary areas: investigating macrophage phenotype composition in atherosclerotic plaques compared to in vitro models, and examining mechanisms underlying acceleration of atherosclerosis in relation to kidney disease. She specifically explores whether development of insulin resistance explains the accelerated atherogenesis observed in kidney disease patients. Her work bridges cardiovascular biology and nephrology, with strong emphasis on molecular mechanisms and biomarker discovery. Analysis of her 15 most recent publications (2021-2025) reveals a consistent research trajectory focused on the intersection of cardiovascular disease and kidney pathology. The publications demonstrate expertise in metabolomics, biomarker identification, and molecular pathways linking kidney dysfunction to cardiovascular complications. Key recurring themes include apolipoprotein M research, macrophage biology in atherosclerosis, and metabolic signatures of disease progression. Dr. Bisgaard maintains active research collaborations across multiple institutions, as evidenced by her co-authorship on publications with researchers from diverse specialties including cardiology, nephrology, and molecular biology. Her work appears in high-impact journals such as Arteriosclerosis, Thrombosis, and Vascular Biology , Clinical Nutrition , and Atherosclerosis . Her laboratory work is conducted within the Physiology of circulation, kidney and lung research group at the Department of Biomedical Sciences, University of Copenhagen, with additional connections to the Diabetes Complications Biology department at Novo Nordisk where she conducts part of her PhD research.