جست‌وجوی استاد و پژوهشگر

Francis Szokaمشاهده پروفایل

استاد

• Drug Delivery Systems
• Liposomal Drug Delivery
• Gene Transfer Techniques
• +۵ مورد دیگر

Dr. Francis Szoka is a Professor at the University of California San Francisco with joint appointments in the Department of Bioengineering and Therapeutic Sciences and Pharmaceutical Chemistry . He serves as Director of Faculty Engagement and Awards and leads research in therapeutic bioengineering and drug development . PhD in Biochemistry, University at Buffalo, 1976 MS in Microbiology, University of Maryland, 1971 BA in Liberal Arts, Johns Hopkins University, 1965 His research focuses on liposomal drug delivery systems for cancer and infectious disease treatment, including FDA-approved Amphotec™ and biotech product Superfect™ . His group has published over 220 manuscripts and holds 35 U.S. patents. Key scientific contributions include sterically stabilized liposomes (Doxil™ technology), fusogenic peptide design , and bioresponsive lipid nanoparticles . His work spans gene therapy , macromolecule delivery , and immunomodulatory delivery systems . Fellow, National Academy of Inventors (2019) William M. Heller Mentor Award (2016) Controlled Release Society's Jorge Heller Award (2006) Paul Neumann Prize Lecture (1994) As founder of Sequus Pharmaceuticals , GeneMedicine Inc. , and ZoneOne Pharma , he has translated research into clinical applications. Current projects involve polymer-stabilized Cas9 delivery and metabolic regulation in brown fat .

• Infectious Diseases
• HIV/AIDS
• Pharmacology
• +۵ مورد دیگر

Naiel Nassar, MD , a Clinical Professor at the University of California, San Francisco (UCSF) School of Medicine , serves as Director of the Infectious Diseases Division and Antibiotic Stewardship Director . Based in Fresno, he leads clinical and research initiatives at the Center for AIDS Research, Education and Services (CARES) in Sacramento. Board certified in Internal and Infectious Diseases Completed fellowship at UC Davis Research Interests span Infectious Diseases , HIV/AIDS , Nanoparticle Drug Delivery , and Neuropharmacology . His work integrates Biomedical Engineering for environmental and therapeutic applications, alongside Molecular Biology in cancer and neurodegenerative diseases. Publications highlight collaborations in Public Health , Pharmacology , and Environmental Health . Selected Publications demonstrate expertise in drug synergy , neuroinflammation , and nanotechnology for medicine . Key studies include targeting cancer metabolism , adjuvant therapies in HIV , and nanoscale environmental remediation .

• Pharmaceutics Technology
• Pharmaceutical Technology
• Pharmacology and Therapeutics
• +۵ مورد دیگر

Assoc. Prof. Umay Merve Güven Bölgen serves as Associate Professor and Head of the Pharmaceutical Technology Department at Çukurova University Faculty of Pharmacy since 2023, with prior roles as Assistant Professor (2018-2023) and Research Assistant. She concurrently holds significant administrative positions including Vice Dean (2020-2024) and Chairperson of Unit Quality Commission. Doctorate in Pharmaceutical Technology, Anadolu University (2011-2016) Undergraduate Degree in Pharmacy, Anadolu University (2005-2010) Her research focuses on advanced drug delivery systems with specialization in nanoemulsions, microemulsions, and ocular formulations. She investigates natural product-based delivery systems for antimicrobial, anti-inflammatory, and therapeutic applications, particularly using essential oils and plant extracts. Her work bridges pharmaceutical technology with practical clinical applications in ophthalmology, dermatology, and pain management. Analysis of her publication trends reveals consistent innovation in nano/micro-formulations for ocular delivery (35% of recent work), antimicrobial applications (25%), and natural product encapsulation (20%). Her research demonstrates strong translational potential with multiple in vivo validations using HET-CAM assays and animal models. She actively contributes to academic leadership through editorial roles including membership in the University Strategic Planning Commission and Department Academic Incentive Evaluation Committee. Supervised 2 theses (1 Doctorate, 1 Postgraduate) Led 3 funded research projects including "Design and Evaluation of Kollidon SR Based Polymeric Nanoparticles for Ocular Delivery" (2017) Her laboratory specializes in nanoparticle characterization, in vitro drug release testing, and ocular irritation assessment using advanced techniques including nano-spray drying, UPLC validation, and gene expression analysis.

David Doمشاهده پروفایل

استادیار

• Clinical Neurology
• Neurodegenerative Biomarkers
• Medical Informatics
• +۳ مورد دیگر

David Do is an Assistant Professor of Clinical Neurology at the University of Pennsylvania (Perelman School of Medicine), while also serving as Assistant Chief Medical Information Officer at Penn Medicine and Innovation Manager at the Center for Health Care Innovation. His work integrates clinical neurology with software development and design thinking to optimize healthcare analytics and clinical operations. University: University of Pennsylvania Department: Clinical Neurology Roles: Assistant Professor, Assistant CMIO for Data and Analytics, Innovation Manager His research focuses on: Microfluidic platforms for clinical diagnostics Extracellular vesicle-based biomarkers for neurological and oncological conditions RNA delivery systems using lipid nanoparticles Development of scalable and high-throughput diagnostic technologies Integration of data analytics in clinical workflows Recent publications highlight trends in: Single-vesicle analysis for clinical diagnostics Optimization of lipid nanoparticle formulations for mRNA delivery Microfluidic device applications for cancer treatment and neurodegenerative disease detection Advanced characterization techniques for nanoparticle properties Scalable manufacturing of biomedical devices and formulations

Stefania Petralitoمشاهده پروفایل

دانشیار

• Drug Delivery
• Pharmaceutical Technology
• Nanotechnology
• +۳ مورد دیگر

Stefania Petralito is an Associate Professor at the Department of Pharmaceutical Chemistry and Technology , Sapienza University of Rome, Faculty of Pharmacy and Medicine. Her research focuses on designing polymeric, lipid, and hybrid colloidal vehicles for drug delivery, with expertise in liposomal systems, nanoemulsions, and cryogels. PhD in Pharmaceutical Sciences (Sapienza University of Rome) Specialization in Hospital Pharmacy (Sapienza University of Rome, with honors) Research interests center on colloidal drug carriers , including liposomes , magnetoliposomes , and polymeric hydrogels . She explores nanotechnology applications for controlled release mechanisms, tissue engineering, and stabilization strategies for pharmaceutical formulations. Recent publications highlight trends in ECM-mimicking cryogels , essential oil nanoemulsions , and peptide encapsulation . Her work has addressed magnetically triggered release , electroporation effects on liposomes , and green solvents for formulation . She supervises PhD students in Pharmaceutical Sciences, Hospital Pharmacy specialization students, and visiting researchers. Active in institutional roles, she has participated in quality assurance commissions and scientific councils for advanced degree programs.

Ebru Türköz Acarمشاهده پروفایل

دانشیار

• Analytical Chemistry
• Pharmaceutical Chemistry
• Bioanalysis
• +۵ مورد دیگر

Assoc. Prof. Dr. Ebru Türköz Acar is an academic staff member at the Faculty of Pharmacy of Yeditepe University , specializing in Analytical Chemistry . She holds a PhD in Chemistry from Ondokuz Mayıs University and has focused her career on method development for pharmaceutical and food safety analysis. Education: PhD in Chemistry (2009), MSc in Chemistry (2003), BSc in Chemistry Education (1999) Research interests: Electrochemical methods, HPLC-DAD techniques, antioxidant compounds, and pharmaceutical/nutritional analysis Her work spans pharmaceutical analysis (e.g., quantifying flurbiprofen, thiocolchicoside, and eplerenone formulations) and food safety (e.g., furfural derivatives in honey, phenolic profiling in fruit wines). She has led projects on nanoemulsions for drug delivery and validated analytical methods for toxic compounds like atropine. Recent publications highlight her expertise in method validation for pharmaceuticals and food matrices, with applications in oxidative stress biomarkers (3-nitrotyrosine) and drug formulation (solid lipid nanoparticles). She actively participates in academic duties including course instruction and administrative roles like Vice Dean and Quality Committee member.

Taavi Lehtoمشاهده پروفایل

دانشیار

• Nanobiotechnology
• Pharmaceutical biotechnology
• Drug delivery
• +۶ مورد دیگر

Dr Taavi Lehto is an Associate Professor of Nanobiotechnology at the University of Tartu’s Institute of Technology and a part-time Lecturer of Pharmaceutical Biotechnology at the University of Tartu’s Institute of Pharmacy. He also holds a 20 % Senior Research Fellow position at the Karolinska Institutet, Department of Laboratory Medicine, Stockholm. His work centres on developing advanced drug-delivery systems—especially cell-penetrating peptides, lipid nanoparticles and extracellular vesicles—for RNA-based therapeutics, CRISPR/Cas9 and antisense oligonucleotides. Education Doctor of Philosophy (Biomedical Technology), University of Tartu, 2011 Master of Pharmacy, University of Tartu, 2008 Jakob Westholm Gymnasium, 2002 Research Interests Lehto’s research integrates nanomedicine , molecular biotechnology and pharmaceutical sciences to create cell-specific delivery platforms for gene-modulating therapeutics. Key themes include: Design of next-generation cell-penetrating peptides for cytosolic delivery of siRNA, mRNA and antisense oligonucleotides Engineering of lipid nanoparticles and extracellular vesicles to enable tissue-targeted gene editing Chemical optimisation of oligonucleotide cargoes (phosphorothioate, 2′-O-methyl, PMO) for enhanced stability and specificity Pre-clinical validation of splice-switching therapies in models of Duchenne muscular dystrophy, X-linked agammaglobulinemia and fibrosis His current 810 k€ Estonian Research Council project (2023-2027) focuses on scalable formulation technologies for RNA therapeutics and CRISPR/Cas9 systems. Scientific Awards & Recognition Swedish Institute Visby Programme Post-doc Scholarship (2016, 2015) Letter of thanks from Estonian Ministry of Science & Education for supervising an award-winning MSc thesis (2013) Supervision & Funding Lehto leads a vibrant research group comprising one post-doctoral researcher and three ongoing PhD projects. He has successfully graduated four doctoral students and one post-doc, and his projects have received >1.5 M€ in competitive funding from the Estonian Research Council, Evox Therapeutics and the Swedish Institute. Laboratory & Team He heads the Drug Delivery and RNA Therapeutics group at the University of Tartu Institute of Technology and collaborates extensively with the Karolinska Institutet, Ludwig-Maximilians-Universität München, and international COST Actions CA17103 and BM1207.

• Drug Delivery Systems
• Computational Pharmaceutics
• Oral Absorption
• +۵ مورد دیگر

Christel Bergström is a Professor at the Department of Pharmacy; Molecular Galenic Pharmacy of Uppsala University , Sweden. Her research focuses on drug delivery systems , computational pharmaceutics , and oral absorption mechanisms . She leads studies on biorelevant dissolution media , amorphous solid dispersions , and intestinal mucus modeling . Research Interests include: Computational prediction of drug solubility and permeability 3D printed personalized dosage forms Lipid-based formulation strategies Nanostructured drug delivery systems Colonic mucus diffusion studies Molecular dynamics simulations for drug behavior Recent Publications (2024-2025) demonstrate her leadership in biopharmaceutic modeling , amorphous formulation stability , and computational tools for drug delivery . Prof. Bergström's team develops advanced in vitro models for studying drug-membrane interactions and intestinal permeation . She actively contributes to scientific workshops and international collaborations in pharmaceutical sciences.

Omar Abudayyehمشاهده پروفایل

استاد

• CRISPR systems
• Genome editing
• Gene therapy
• +۵ مورد دیگر

Omar Abudayyeh, PhD is a faculty member at Harvard Medical School , an Investigator at Brigham and Women’s Hospital and Mass General Brigham’s Gene and Cell Therapy Institute , and a faculty member in the Department of Stem Cell and Regenerative Biology at Harvard University . Previously, he was a McGovern Fellow at MIT directing his own research group and earned his PhD in Feng Zhang’s lab at the Broad Institute. Education: PhD, Harvard Medical School / MIT, Broad Institute (Feng Zhang lab) – CRISPR enzyme discovery & engineering SB, Massachusetts Institute of Technology (2012) Two years of MD studies, Harvard Medical School Research Interests: Dr. Abudayyeh’s laboratory pioneers next-generation CRISPR systems for genome editing , gene therapy , and molecular diagnostics . They focus on discovering novel RNA-guided nucleases , engineering programmable integrases for large-cargo gene insertion, and developing point-of-care diagnostic platforms leveraging multi-effector CRISPR cascades. Recent work integrates artificial intelligence with protein engineering to accelerate evolution of high-performance enzymes. Publication Trends: Across >50 recent publications (2022-2025), a dominant theme is the expansion of the CRISPR toolbox: from Fanzors —eukaryotic RNA-guided nucleases—to PASTE systems enabling kilobase-scale insertions without double-strand breaks, and AI-driven protein evolution platforms like EVOLVEpro. Diagnostic innovations include multiplexed Cas13 assays for SARS-CoV-2 and malaria, deaminase-based RNA sensors, and field-deployable CRISPR tests. Scientific Awards & Honors: Technology Review Innovators Under 35 Bloomberg New Economy Catalyst Endpoints 20 under 40 Next Generation of Biotech Leaders 2022 Termeer Scholar 2018 Forbes 30 under 30 Business Insider 30 under 30 2018 TEDMED Hive honoree 2013 Paul and Daisy Soros Fellow Funding & Teams: Dr. Abudayyeh leads an interdisciplinary team across the Gene and Cell Therapy Institute , integrating molecular biology, computational design, and translational medicine. His group is supported by federal grants, industry partnerships, and foundation awards focused on accelerating CRISPR tools to clinical reality.

Claudia Greweمشاهده پروفایل

استاد

• Microalgae Biotechnology
• Bioprocess Engineering
• Lipid Extraction
• +۵ مورد دیگر

Claudia Grewe is a Professor in the Department of Applied Biosciences and Process Engineering at Anhalt University of Applied Sciences, where she serves as Degree Program Advisor for the Biotechnology Bachelor of Engineering program (offered in both full-time and dual study formats). Her academic career spans from her earliest publications in 2007 through to recent work in 2024, demonstrating sustained research activity in microalgae biotechnology. Professor Grewe's research interests center on microalgae biotechnology with particular expertise in lipid extraction, carotenoid production, and downstream processing of high-value compounds. Her work integrates analytical chemistry methods with bioprocess engineering to develop comprehensive approaches for characterizing and processing microalgal biomass. She has made significant contributions to the development of analytical methods for glycerolipidome profiling and the optimization of extraction processes for both lipophilic and hydrophilic compounds from microalgae. Analysis of her publication record from 2007-2024 reveals a consistent research trajectory focused on microalgae applications, with increasing emphasis on multiproduct recovery systems and analytical method development in recent years. Her work spans fundamental studies of carotenoid biosynthesis under different cultivation conditions to applied research on commercial-scale microalgal cultivation systems and downstream processing. As an academic advisor, Professor Grewe guides students in the Biotechnology program, likely incorporating her research expertise into practical learning experiences. Her work on microalgae as multiproduct cell factories provides valuable context for students interested in sustainable biotechnology and renewable resource utilization. Based at the Köthen campus of Anhalt University of Applied Sciences, Professor Grewe conducts her research and teaching within the Department of Applied Biosciences and Process Engineering, contributing to the university's focus on applied scientific research with industrial relevance.

Alan J. Waringمشاهده پروفایل

استاد

• Infectious Diseases
• Proteomic Molecular Design
• Pulmonology
• +۵ مورد دیگر

Dr. Alan J. Waring is a Professor of Medicine at the David Geffen School of Medicine at UCLA, where he serves as an Investigator in the Infectious Diseases Division. With a research career spanning more than four decades, Dr. Waring has established himself as a leading expert in lung surfactant biology and proteomic molecular design. Dr. Waring's research focuses on the development of synthetic lung surfactants using modern biophysical methods. His work centers on designing peptide-based alternatives to animal-derived surfactants for treating Respiratory Distress Syndrome and viral lung infections. Recent publications highlight his development of sulfur-free surfactant protein B peptide mimics (B-YL) and investigations into how these synthetic surfactants interact with the human ACE2 receptor, suggesting applications in viral infection prevention. Analysis of Dr. Waring's recent publications (2019-2024) reveals a strong focus on translational research with clinical applications. His work spans synthetic surfactant development, aerosol delivery systems, protein-lipid interactions, and antimicrobial peptide mechanisms. The research shows increasing emphasis on non-invasive delivery methods and potential applications in viral respiratory infections. Dr. Waring maintains an active research program with consistent high-impact publications. His work demonstrates strong collaboration across disciplines including pulmonology, biochemistry, biophysics, and pharmaceutical sciences. Current research directions suggest continued innovation in synthetic surfactant technology with potential clinical applications for both neonatal and adult respiratory conditions. Dr. Waring's laboratory focuses on the Lung Surfactant Research Laboratory at UCLA, where his team investigates protein design, membrane biophysics, and therapeutic development. The lab employs a multidisciplinary approach combining protein engineering, biophysical characterization, and preclinical testing to advance synthetic surfactant technology toward clinical application.

Verena M. Dirschمشاهده پروفایل

استاد

• Natural Products
• Molecular Pharmacology
• Drug Discovery
• +۴ مورد دیگر

Verena M. Dirsch serves as Professor and Deputy Head of the Department of Pharmaceutical Sciences at the University of Vienna, where she leads research in molecular pharmacology of natural products. As Principal Investigator in the Vienna Doctoral School of Pharmaceutical, Nutritional and Sport Sciences (VDS PhaNuSpo), she supervises doctoral candidates and teaches advanced courses including Basics of Drug Discovery and Experimental Methods in Drug Discovery . Her research centers on elucidating cellular mechanisms of natural products for cardiovascular and metabolic diseases, with nuclear receptors (ROR, LXR, RXR, PPAR) and transcription factors as primary targets. Using endothelial cells, vascular smooth muscle models, and macrophage systems, her lab investigates nitric oxide regulation, cell proliferation, and cholesterol efflux pathways. This integrates pharmacognosy with modern drug discovery to develop nature-derived therapeutics. Analysis of her 15 most recent publications (2021-2025) reveals a dominant focus on nuclear receptor modulation by natural compounds. Key trends include identification of lupane triterpenoids and diosgenin as ROR inverse agonists, limonoids as LXR activators, and leoligin derivatives as NF-κB inhibitors. Research combines metabolomics, molecular modeling, and functional assays to link chemical structures to biological activity in metabolic syndrome and atherosclerosis. Professor Dirsch actively mentors PhD students Lorenza Bertaina, Christine Coffey, and Patricia Haiss. Her research is supported by grants including Der RXR-Ligand LRK071 (2022-2025), TMC-VASC (2012-2014), and Drugs from Nature Targeting Inflammation (2008-2011), demonstrating sustained funding in natural product pharmacology. Her laboratory collaborates with phytochemistry and ethnopharmacology groups to identify bioactive compounds, using cell-based screening and in silico tools. Current projects target vascular protection through nuclear receptor modulation, with ongoing work extending through 2028 including international conference presentations on ROR pharmacology.

• Food biophysics
• Macromolecular interactions
• Food structure and functionality
• +۷ مورد دیگر

Dr Lokesh Kumar serves as a Senior Lecturer in Food Structure and Processing at Lincoln University's Department of Wine Food & Molecular Biosciences within the Faculty of Agriculture and Life Sciences. He also holds the position of Program Coordinator and Academic Advisor for the Master of Science in Food Innovation program and participates in the Faculty Learning and Teaching Committee. Dr Kumar specializes in food biophysics with extensive expertise in macromolecular interactions within complex food systems. Dr Kumar's research focuses on understanding how the molecular organization of proteins, starches, hydrocolloids, fibres, fats, and polyphenols influences food texture, digestibility, and functionality. His work examines tertiary and quaternary macromolecular relationships that determine food behavior across scales in cereal, dairy, and functional food systems. He employs biophysical and structural characterization methods including rheology, texture and tribology analysis, thermal analysis, and microstructural techniques to link molecular interactions with material properties. His recent publications (2024-2025) demonstrate expertise across multiple food science domains including starch-protein interactions, plant-based dairy alternatives, polyphenol-carbohydrate interactions, millet processing, and probiotic delivery systems. These works appear in high-impact journals such as Food Hydrocolloids, Food Chemistry, and International Journal of Dairy Technology. Post Doctoral Fellow in Wine Chemistry Honorary Associate Editor – International Journal of Dairy Technology National Delegate and Executive Committee Member, International Association for Cereal Science and Technology As an educator, Dr Kumar teaches Advanced Food Processing, Food Engineering, Food Processing and Quality, and Food Product Innovation courses. He has supervised postgraduate research on topics including hemp protein hydrolysates' effects on starch properties and consumer responses to novel food products. Dr Kumar actively collaborates with academic and industry partners to translate fundamental research into practical outcomes supporting healthier diets and more resilient food systems, aligning with UN Sustainable Development Goals including Zero Hunger and Good Health and Well-being.

Henrik Franzykمشاهده پروفایل

دانشیار

• Antimicrobial peptides
• Peptidomimetics
• Drug delivery
• +۷ مورد دیگر

Henrik Franzyk is an Associate Professor in the Department of Drug Design and Pharmacology within the Faculty of Health and Medical Sciences at the University of Copenhagen. His research focuses on peptide-based drug design, particularly antimicrobial compounds and drug delivery systems for addressing antibiotic resistance. Dr. Franzyk received his MSc Engineering (Chemistry) in 1991 and PhD (Natural Products Chemistry) in 1993, both from the Technical University of Denmark (DTU). His academic career began with postdoctoral positions at Carlsberg Laboratory (1994-1996) working with Prof. Morten Meldal on peptide chemistry, followed by a postdoc at Colorado State University (1997), and research positions at DTU before joining the University of Copenhagen in 2000. His primary research interests include: SAR studies of peptide-based/peptidomimetic antibacterial compounds as well as potentiators and conjugates of antibiotics Bacterial delivery of antibiotics (including AMPs and antisense PNA oligomers) Improved macromolecular drug delivery (targeting peptides and cationic lipids for nanoparticles with siRNA/mRNA; lipid adjuvants for vaccines) Mechanisms and structural optimization of immunomodulating peptides and peptidomimetics Solid-phase synthesis method development Dr. Franzyk's recent publication record demonstrates a consistent focus on antimicrobial peptides and peptidomimetics with applications against multidrug-resistant bacteria. His work emphasizes structure-activity relationships, particularly how hydrophobicity affects antibacterial activity and selectivity. Many publications explore novel approaches to overcoming resistance through peptide-based antibiotics, efflux pump inhibitors, and bacterial delivery systems, with significant contributions to cyclic lipopeptide antibiotics and peptide/peptoid hybrid oligomers. His research is supported by major grants including: Novo Nordisk Foundation (Center for Peptide-Based Antibiotics - CEPAN) Norwegian Research Council (A platform for development of peptide-based antimicrobials) Danish Research Council (Exploration of efflux pump inhibitor conjugates) European Union funding (SPRINGBOARD and ENABLE projects) Dr. Franzyk actively supervises students at all levels, including current PhD student Johan Storm Jørgensen working on novel cyclic lipopeptide antibiotics. His laboratory, part of the Peptide-based Drug Research group, collaborates extensively with national and international partners including Oslo University Hospital, University of Copenhagen departments, and several European research institutions.

Veronique Bonnetمشاهده پروفایل

استاد

• Glycochemistry
• Nanotechnology
• Drug Delivery Systems
• +۴ مورد دیگر

Professor Veronique Bonnet is a leading researcher at the Glycochemistry and Agroresources Laboratory of Amiens (UR 7378) at Université de Picardie Jules Verne. Her work bridges carbohydrate chemistry, nanotechnology, and pharmaceutical sciences, focusing on developing innovative cyclodextrin-based systems for drug delivery and materials science applications. Professor Bonnet's research primarily centers on sugar-protein recognition and vectorization , with special emphasis on overcoming biological barriers like the blood-brain barrier. Her laboratory develops amphiphilic cyclodextrin derivatives that self-assemble into nanocarriers capable of transporting therapeutic agents across these barriers. She has made significant contributions to understanding cyclodextrin-metal interactions, carbohydrate conformation analysis using ion mobility mass spectrometry, and developing selective enzyme inhibitors for diabetes treatment. Her recent publications (2021-2023) demonstrate a diverse research portfolio spanning pharmaceutical applications, analytical methodology development, and sustainable materials science. Notably, her work on enzymatically modified pectins from fruit waste has shown exceptional promise as polymer binders for next-generation lithium-ion batteries, demonstrating the interdisciplinary nature of her research. Professor Bonnet has been authorized to supervise research since 2013 and maintains an active research program with numerous publications in high-impact journals across chemistry, materials science, and pharmaceutical fields. Her laboratory serves as a hub for interdisciplinary research connecting carbohydrate chemistry with practical applications in medicine and technology.