جست‌وجوی استاد و پژوهشگر

Kelly Arnoldمشاهده پروفایل

دانشیار

• Biomedical Computation and Modeling
• Drug Delivery and Therapeutics
• Systems Immunology
• +۵ مورد دیگر

Kelly Arnold is an Associate Professor in the Department of Biomedical Engineering at the University of Michigan. Her research integrates systems engineering principles with immunology to investigate variability in immune responses across infection, vaccination, and injury, with a focus on computational modeling and clinical translation. Research Focus Systems-level immune response modeling Vaccination and antibody functionality Vaginal microbiome-host interactions Chronic lung disease progression Computational serology and proteomics Recent Work Her 2025 studies examine SARS-CoV-2 vaccination responses in cancer patients and computational frameworks for vaginal probiotics. Earlier works (2024-2007) span COPD progression, lupus fibrosis, HIV susceptibility, and tissue engineering for fertility preservation. Methodologies include proteomic profiling, network modeling, and microfluidic systems.

Waldemar Kolanusمشاهده پروفایل

استاد

• Molecular Immunology
• Cell Signaling
• Signal Transduction Pathways
• +۴ مورد دیگر

Prof. Waldemar Kolanus leads the Molecular Immunology and Cell Biology department at the University of Bonn's Life & Medical Sciences Institute (LIMES) . His research bridges immunoregulation , stem cell dynamics , and metabolic stress responses in immune cells. Unit 2 member at LIMES Principal investigator in SFB 704 and ImmunoSensation Cluster Leads a multidisciplinary lab with postdocs, PhD students, and technical staff His work focuses on intracellular signaling pathways connecting immune activation to tissue homeostasis, particularly through: Cytohesin proteins in integrin-mediated adhesion and migration TRIM71 in stem cell regulation and congenital hydrocephalus High-salt environments affecting macrophage function Publication trends show expertise in immune cell migration , genetic models , and chemical inhibition , with frequent use of mice and zebrafish for in vivo studies. Key articles explore: TRIM71's dual role in auditory development and germ cell maintenance Cytohesin family's Golgi regulation and insulin signaling Ruxolitinib's off-target migration inhibition of dendritic cells Contact details: Address: LIMES Institute, Carl-Troll-Straße 31, Bonn Email: kolanus.sekretariat@uni-bonn.de Phone: +49 228 73-62788

Jessica Williamsمشاهده پروفایل

استادیار

• Neuroimmunology
• Multiple Sclerosis
• Astrocyte Biology
• +۵ مورد دیگر

Jessica Williams, PhD is an Assistant Professor in the Department of Neurosciences at the Cleveland Clinic Lerner Research Institute (LRI) with additional faculty appointments at Case Western Reserve University, Kent State University, and Cleveland State University. She serves as the Cleveland Clinic liaison for Kent State University and represents the Clinic on the Executive Council for the Brain Health Institute and the Biomedical Sciences Graduate Program Executive Committee. Education: Postdoctoral Fellowship in Neuroimmunology, Washington University School of Medicine (2017) Ph.D. in Immunology, The Ohio State University (2011) M.S. in Physiology, Purdue University (2006) B.S. in Biology/Chemistry, Lindenwood University (2004) Dr. Williams' research focuses on neuroimmune interactions during multiple sclerosis, particularly examining regional responses of CNS glia to immune stimuli and astrocyte-immune crosstalk. Her lab employs murine MS models, primary human and murine cell analyses, and MS patient lesion assessment to investigate cytokine-mediated neuroprotection and CNS repair mechanisms. Recent work highlights protective astrocyte functions mediated by traditionally deleterious cytokines. Analysis of her 15 most recent publications reveals consistent focus on neuroimmune crosstalk in MS, with increasing emphasis on astrocyte heterogeneity, cytokine signaling (particularly IFNγ), and novel therapeutic targets like immunoproteasomes. Key themes include regional CNS differences in immune responses, glial cell repair mechanisms, and translating basic findings into potential MS therapies. Scientific Awards: Lerner Research Institute Excellence in Education Award (2022) Mentor of the Year Award (2023) Dr. Williams actively mentors the next generation of scientists as evidenced by her CIMER Trained Mentor certification and the graduation of PhD student Brandon Smith. Her research is supported by significant funding from the NIH, National MS Society, W.M. Keck Foundation, Brain Health Research Institute, and Neurological and Vision Impact Area. She regularly serves on study sections for the NIH, National MS Society, and Department of Defense. The Williams Laboratory investigates the interplay between immune and central nervous systems during MS, with current projects examining cytokine-mediated neuroimmune crosstalk for CNS repair and regionally distinct glial responses to inflammation. The lab employs advanced techniques including murine MS models and primary human cell analyses to identify novel therapeutic pathways for MS patients.

Anil Kumarمشاهده پروفایل

استادیار

• Molecular Virology
• Virus-host Interactions
• Innate Immune Response
• +۳ مورد دیگر

Dr. Anil Kumar is an Assistant Professor in the Department of Biochemistry, Microbiology & Immunology at the University of Saskatchewan's College of Medicine. He specializes in molecular virology, focusing on positive-stranded RNA viruses and their interactions with host immune systems. His research employs high-throughput genetic screens and reverse genetics systems to identify host factors critical for viral infection. Education includes a BSc in Agricultural Sciences (1999, Kerala Agricultural University), MSc in Plant Pathology (2001, Indian Agricultural Research Institute), and PhD in Molecular Virology (2010, University of Heidelberg). Postdoctoral training included stints at the University of Heidelberg (2010–2013) and the University of Alberta (2014–2020). Research interests center on Eastern Equine Encephalitis virus (EEEV) and Enterovirus D68 (EV-D68). For EEEV, his lab investigates immune evasion mechanisms and host-virus protein interactions to identify therapeutic targets. For EV-D68, they study CNS invasion mechanisms and novel host dependency factors linked to acute flaccid myelitis (AFM). Recent work includes studies on SARS-CoV-2, uncovering roles for host proteins like Argonaute 2 in viral restriction. His lab integrates molecular biology, virology, and systems biology approaches, with a focus on translational research for antiviral drug development. Collaborations include work on respiratory syncytial virus (RSV) entry mechanisms and dengue virus replication regulation.

Jeff Schoreyمشاهده پروفایل

استاد

• Microbiology
• Immunology
• Infectious Diseases
• +۹ مورد دیگر

Jeff Schorey is the George B. Craig Jr. Professor and a full Professor in the Department of Biological Sciences at the University of Notre Dame, where he has been a faculty member since 2004. He currently serves as Director of the Integrated Biomedical Sciences (IBMS) graduate program and previously held leadership roles including Chair of the Institutional Animal Care and Use Committee (IACUC) and Associate Director of the Eck Institute for Global Health. His research focuses on the pathobiology of mycobacterial diseases, particularly Mycobacterium tuberculosis and M. avium . His work investigates the molecular interactions between mycobacteria and host macrophages, with a special emphasis on the role of exosomes in immune modulation, diagnostics, and vaccine development. He also explores novel antibiotic development in collaboration with chemists at Notre Dame and global partners. His recent publications reveal a strong trend in extracellular vesicle biology, host-pathogen signaling, and translational applications in TB diagnostics and treatment. The articles span immunology, microbiology, and molecular biology, with recurring themes in exosome function, RNA sensing, and antimicrobial development. George B. Craig Jr. Collegiate Professor Dr. Schorey has advised graduate students and leads an active research lab focused on mycobacterial pathogenesis. His work is supported by collaborations across disciplines and institutions, particularly in drug development and clinical translation. He has contributed significantly to understanding how exosomes can serve as both biomarkers and therapeutic tools. His lab employs cellular immunology, animal models, and clinical sample analysis to study mycobacterial infections. He leads the IBMS program, shaping graduate education in biomedical sciences at Notre Dame.

Caetano Reis e Sousaمشاهده پروفایل

استاد

• Immunology
• Infectious Disease
• Cancer Immunotherapy
• +۳ مورد دیگر

Caetano Reis e Sousa is a Professor of Immunology at Imperial College London and Senior Group Leader/Assistant Research Director at the Francis Crick Institute. He leads the Immunobiology Laboratory, focusing on dendritic cell biology, immune responses to pathogens, and cancer immunotherapy. His research explores how dendritic cells detect pathogens and dying cells, triggering adaptive immunity. Key roles include investigating cross-presentation mechanisms, C-type lectin receptors (e.g., DNGR-1), and vaccine development strategies. Education: BSc (Hons) Biology from Imperial College London (1989), DPhil in Immunology from University of Oxford (1992). Postdoctoral training at NIH under Ron Germain. Career milestones include founding the Immunobiology Lab at CRUK London Research Institute (1998–2015) before joining the Crick. Awards & Recognition: Highly Cited Researcher (Thomson Reuters), BD Biosciences Prize (2002), Liliane Bettencourt Award (2008), Louis-Jeantet Prize (2017), Fellowships at Royal Society (2019), Academy of Medical Sciences (2006), and EMBO (2006). Named Officer of the Order of Sant'Iago da Espada (Portugal, 2009). Research Themes: Dendritic cell activation pathways, cross-presentation of tumor antigens, microbiome-cancer immunity links, and immune evasion mechanisms. Collaborations involve institutions like UCL, King's College London, and global health networks. Labs/Teams: Head of Immunobiology Lab at Crick, with expertise in immunology, cell biology, and virology. Facilities include Flow Cytometry, Genomics, and Light Microscopy cores. Active in pandemic response (e.g., SARS-CoV-2 testing initiatives).

Bertram Müller-Myhsokمشاهده پروفایل

استاد پژوهشی

• Psychiatric Genetics
• Statistical Genetics
• Transcriptomics
• +۳ مورد دیگر

Bertram Müller-Myhsok is a Research Professor and Research Group Leader at the Max Planck Institute of Psychiatry in Munich, Germany. His research focuses on statistical genetics and transcriptomic data analysis in psychiatric disorders, particularly major depression, PTSD, schizophrenia, and their treatment responses. He integrates machine learning with genetic and clinical data to develop predictive models and stratified treatment approaches. Professional activities include leadership roles in the International Max Planck Research School for Translational Psychiatry and collaborations with institutions like the Institut du Cerveau (Paris) and Bernhard Nocht Institute (Hamburg). His work spans genetic epidemiology, psychiatric genomics, and precision medicine, with over 400 publications in high-impact journals. Key research areas include identifying genetic risk factors for mental disorders, developing polygenic scores, and leveraging omics data to uncover disease mechanisms. He leads projects like Psych-STRATA, a Horizon Europe-funded initiative advancing personalized psychiatry through pharmacogenomics.

Montserrat Angueraمشاهده پروفایل

دانشیار

• Epigenetics
• X-Chromosome Inactivation
• Long Noncoding RNAs
• +۶ مورد دیگر

Montserrat Anguera, Ph.D. is an Associate Professor in the Department of Biomedical Sciences at the University of Pennsylvania's School of Veterinary Medicine. Her research focuses on epigenetic mechanisms of gene regulation underlying sex differences in development and disease, with particular emphasis on X-chromosome inactivation (XCI) and its implications for female-biased autoimmune disorders. Dr. Anguera investigates how gene expression from the X-chromosome is regulated to ensure dosage compensation between males and females, and how these mechanisms become altered in diseases exhibiting sex-bias. Her laboratory has established novel epigenetic pathways involving the X-chromosome that impact human development, immune responses, and lymphocyte function. She employs advanced techniques including RNA/DNA fluorescence in situ hybridization, immunofluorescence, and allele-specific RNA sequencing to achieve single-cell resolution of epigenetic characteristics of the inactive X chromosome. Her research reveals a consistent focus on the intersection of X-chromosome biology and immunology, particularly regarding sex-biased autoimmune diseases like systemic lupus erythematosus. Key findings include the discovery that lymphocytes maintain X-chromosome inactivation differently than other somatic cells, with the inactive X exhibiting euchromatic features in female lymphocytes that may underlie female bias in autoimmune disorders. She coined the term 'dynamic XCI maintenance' to describe how T and B cells relocalize Xist RNA and heterochromatic marks to the inactive X chromosome following antigen-mediated stimulation. Dr. Anguera's laboratory includes postdocs Katherine Forsyth and Nikhil Jiwrajka, research specialist Zowie Searcy, graduate students Isabel Sierra and Natalie Toothacre, postdoctoral researcher Nuriban Valero-Pacheco, and PhD student Emma Welter. Together, they investigate epigenetic regulation of X-linked genes in development and disease contexts. She is an active member of multiple prestigious research institutes at Penn, including the Epigenetics Institute, Institute for Immunology, Center for Research on Reproduction & Women's Health, and Institute for Regenerative Medicine. Her work bridges epigenetics, immunology, and developmental biology, providing novel insights into mechanisms underlying female-biased autoimmune disorders.

Yukiko Gotohمشاهده پروفایل

استاد

• Neural Development
• Neural Stem/Progenitor Cells
• Epigenetics
• +۷ مورد دیگر

Yukiko Gotoh is a Professor at the Department of Pharmaceutical Sciences, Graduate School of Pharmaceutical Sciences, The University of Tokyo. She serves as the Deputy Director and Principal Investigator at the International Research Center for Neurointelligence (IRCN). Her research focuses on understanding the mechanisms that regulate neural stem/progenitor cell fate during embryonic brain development and in the adult brain. Dr. Gotoh's research interests include: Genetic and epigenetic regulation of neural stem/progenitor cell fate Neuronal maturation processes Genesis and maintenance of adult neural stem cells Relevance of neural stem/progenitor cell dysregulation in neurodevelopmental disorders such as autism spectrum disorders Investigation of mechanisms regulating neural stem-progenitor cell fate during neocortical development Genetic and epigenetic regulation of neuronal activation Analysis of Dr. Gotoh's recent publications reveals a strong focus on neural stem cell biology, epigenetic regulation, and neurodevelopmental disorders. Her work demonstrates how chromatin modifiers like Polycomb group proteins and HMGA proteins regulate neural stem cell fate decisions during brain development. A significant portion of her research explores the embryonic origins of adult neural stem cells and how dysregulation of these processes contributes to conditions like autism spectrum disorders and schizophrenia. Her laboratory also investigates the basic mechanisms of cellular responses to viral infection in the brain and their relevance to neurodevelopmental disorders. Dr. Gotoh has made significant contributions to understanding: The role of Polycomb group proteins in neural development How chromatin modifiers regulate neurogenic potential Cell cycle regulation in neural stem cells The PDK1-Akt pathway in neuronal migration Layer-specific heterogeneity of astrocytes Mechanisms underlying schizophrenia-related abnormalities Dr. Gotoh's laboratory conducts research on multiple fronts related to neural development and stem cell biology. Her team investigates: Mechanisms regulating neural stem-progenitor cell fate during neocortical development Genetic and epigenetic regulation of neuronal activation The embryonic origin of adult neural stem cells Dysregulation of neural stem-progenitor cell and neuronal fate in neurodevelopmental disorders Innate immune responses in the brain

J. Christopher Loveمشاهده پروفایل

استاد

• Nano-based drugs
• Precision medicine
• Immunology
• +۳ مورد دیگر

J. Christopher Love is the Raymond A. (1921) and Helen E. St. Laurent Professor of Chemical Engineering at MIT, with affiliations to the Koch Institute for Integrative Cancer Research, Broad Institute, and Ragon Institute. He earned a BS in Chemistry from the University of Virginia and a PhD in Physical Chemistry from Harvard University under George Whitesides, followed by postdoctoral work under Hidde Ploegh at Harvard Medical School. His research focuses on single-cell analysis, precision medicine, and biomanufacturing. The Love Lab develops technologies for drug discovery, vaccine development, and equitable biologic medicine production. Notable successes include pioneering single-cell analysis platforms, advancing metastatic cancer diagnostics via liquid biopsies, and engineering yeast-based vaccine manufacturing. Recent articles highlight innovations in liquid biopsy sensitivity, AI-driven ECG diagnostics, and CAR T-cell therapies. Awards include the Keck Young Scholar (2009), Dana Scholar (2009), and Camille Dreyfus Teacher-Scholar. He co-founded OneCyte, HoneyComb, and Sunflower Therapeutics, and advises multiple biotech companies. His lab emphasizes translational research, integrating chemical and biological engineering principles to address global healthcare challenges. Current work explores manufacturability-by-design for vaccines, tumor immunology, and mucosal vaccine delivery systems.

Anna G Orrمشاهده پروفایل

استادیار

• Neuroscience
• Neurodegenerative Diseases
• Astrocyte Biology
• +۵ مورد دیگر

Anna G Orr serves as Nan and Stephen Swid Assistant Professor of Frontotemporal Dementia Research and Assistant Professor of Neuroscience at Weill Cornell Medical College's Brain and Mind Research Institute since 2016, leading pioneering research on astrocyte biology in dementia pathogenesis. Her educational background includes: Ph.D. from Emory University (2008) B.S. from Allegheny College (2002) Dr. Orr's research program centers on astrocytic-neuronal interactions , mitochondrial signaling , and neuroimmune mechanisms through three interconnected pathways: neuroimmune , oxidative , and G protein-coupled signaling . Her lab investigates how these mechanisms influence neuroinflammation, protein aggregation, synaptic function, and behavioral outcomes in dementia, with parallel therapeutic discovery efforts targeting astrocytic pathways for novel dementia treatments. Analysis of her 15 most recent publications (2025-2010) reveals escalating focus on astrocyte-specific dementia mechanisms , particularly mitochondrial ROS signaling, sex-dimorphic memory effects, TDP-43 pathology interactions with antiviral pathways, and lipid dysregulation in neurodegeneration. Her work consistently bridges molecular discoveries with therapeutic applications, demonstrating increasing NIH funding support for translational approaches. Key scientific recognitions include: NIH K99/R00 Pathway to Independence Award (2017) Leon Levy Fellowship in Neuroscience (2021) Nan and Stephen Swid Endowed Professorship (2021) Outstanding Neuroscience Teaching Award (2021) Dr. Orr actively mentors eight trainees across career stages, including Ph.D. candidates Evelyn Hardin and Constance Zhou, while securing major NIH grants as Principal Investigator for projects like Uncovering Dementia-Related Lipid Alterations in Astrocytes (NIA 2024-2026) and Mitochondrial Complex III Free Radicals in Dementia Pathology (NIA 2020-2026), alongside collaborative awards from the Alzheimer's Association. Her Orr Lab maintains a dual focus on mechanistic astrocyte biology and therapeutic translation, with current projects examining astrocytic TDP-43 dysregulation, mitochondrial complex III signaling, and sex-specific memory mechanisms using advanced in vivo techniques and disease models.

Andrew Bassettمشاهده پروفایل

پژوهشگر

• Genome Engineering
• Neurodegenerative Diseases
• Stem Cell Research
• +۵ مورد دیگر

Dr. Andrew Bassett serves as Head of the Cellular and Gene Editing Research group at the Wellcome Sanger Institute, where he develops cutting-edge genome engineering techniques using human pluripotent stem cells to investigate neurodegenerative diseases including Alzheimer's and Parkinson's. His work focuses on scaling genetic screening approaches and improving CRISPR specificity for modeling complex disease mechanisms. His academic training includes: PhD at the MRC Laboratory of Molecular Biology (MRC-LMB) with Andrew Travers on chromatin remodelling in heterochromatin formation Postdoctoral research with David Baulcombe at the University of Cambridge studying small RNA roles in chromatin modification Additional postdoctoral work with Chris Ponting at the MRC Functional Genomics Unit (MRC-FGU) in Oxford, where he pioneered CRISPR applications in Drosophila Bassett's research program centers on developing advanced genome engineering methodologies for precise modulation of gene expression networks during development and neurodegeneration. His group specializes in creating complex editing events (SNPs, paired knockouts, enhancer perturbations) within iPSC-derived models, with particular emphasis on epigenetic regulation and transcriptional control. Current projects integrate single-cell 'omics and phenotypic assays to decode genetic causes of neurodegenerative disorders through the OpenTargets consortium. Analysis of his 15 most recent publications reveals dominant trends in CRISPR technology development (35%), neurodegenerative disease modeling (30%), and single-cell functional genomics (25%). His work consistently bridges methodological innovation with disease mechanism studies, increasingly incorporating multi-omics approaches and expanding into cancer immunology and infectious disease applications since 2022. As group leader, Bassett mentors postdoctoral researchers and PhD students while securing major funding for genome engineering initiatives. His team operates within the Sanger Institute's Cellular Operations division and maintains critical partnerships with the OpenTargets consortium for therapeutic target validation. The laboratory specializes in high-throughput screening platforms using iPSC-derived neural and microglial models, with recent methodological advances including scSNV-seq and ONE-STEP tagging systems that significantly enhance precision genome editing capabilities.

Shabaz Mohammedمشاهده پروفایل

دانشیار

• Proteomics
• Mass Spectrometry
• Post-translational Modifications
• +۴ مورد دیگر

Shabaz Mohammed is an Associate Professor of Proteomics at the University of Oxford, holding joint appointments in the Departments of Chemistry and Biochemistry. Since 2020, he has served as Head of the Mechanistic Proteomics research programme at the Rosalind Franklin Institute. His research focuses on advancing proteomics technologies to study protein post-translational modifications and their roles in cellular processes, with applications in viral infections and disease mechanisms. Education: BSc in Chemistry, UMIST (now The University of Manchester), 1999 PhD in Biological Mass Spectrometry, University of Manchester, 2003 Postdoctoral Research, University of Southern Denmark (with Ole Jensen), 2005-2008 Postdoctoral Research, Utrecht University (with Albert Heck), 2008 Professor Mohammed's research centers on developing novel mass spectrometry approaches for large-scale characterization of protein post-translational modifications (PTMs). His group innovates in chromatographic techniques for single-cell proteomics, creates materials for PTM enrichment (glycosylation/phosphorylation), and applies these tools to study viral infections (SARS-CoV-2), cell cycle regulation, and signaling pathways. His work bridges chemistry, biochemistry, and cell biology to understand dynamic protein functions in health and disease. His recent publications (2023-2025) demonstrate strong emphasis on viral proteomics, particularly virus-host RNA-binding protein interactions, and innovations in mass spectrometry fragmentation techniques and chromatography. Key themes include viral remodeling of host cells, new labeling strategies for PTMs, and advancements in single-cell proteomics, with significant implications for understanding viral pathogenesis. Scientific Awards: No specific awards or fellowships were detailed in the source material. Advising and Grants: Information regarding graduate students supervised or specific research grants was not provided in the available text. As an active research group leader, Professor Mohammed likely mentors PhD students and secures competitive funding for proteomics research. Laboratories and Collaborations: Professor Mohammed leads a research group at Oxford focused on proteomics technology development. He collaborates extensively with the Ben Davis group on PTM detection materials and across the university on biochemical applications. At the Rosalind Franklin Institute, he heads the Mechanistic Proteomics programme to unravel protein functions through advanced proteomic methods.

Feyruz V. Rassoolمشاهده پروفایل

استاد

• DNA damage and repair
• Genomic instability
• Epigenetic therapy
• +۷ مورد دیگر

Feyruz V. Rassool is a Professor at the University of Maryland School of Medicine, with primary appointment in Radiation Oncology. She serves as Co-director of the Experimental Therapeutics Program at the University of Maryland Greenebaum Comprehensive Cancer Center (UMGCCC) and holds an adjunct Associate Professor position at VARI’s Center for Epigenetics. Her research focuses on DNA damage/repair pathways in cancer, particularly their therapeutic exploitation through PARP and DNMT inhibitors. Education: B.Sc. in Human Genetics (1983, University College London), Ph.D. in Biological Sciences (1990, Royal Postgraduate Medical School) Postdoctoral Training: University of Chicago (1990-1994) Her work explores the intersection of DNA repair , epigenetics , and mitochondrial dysfunction to develop novel therapies for breast, ovarian, lung, and leukemias. Key projects include STING-dependent interferon signaling , pathogen mimicry in cancer cells, and metastasis suppression through PARPi/epigenetic combinations. Dr. Rassool is part of the SU2C Epigenetics Dream Team and has secured multiple grants from NCI, NIH, and the Adelson Medical Research Foundation. Her recent preclinical studies with PARP/DNMT inhibitors are being translated into Phase I/II trials for AML and TNBC. Scientific Awards Ziskin Award (2012) NCI-SPORE Grant Co-Leader NIH/NCI P30 CA134274 Support Grant She has mentored 13 PhD/postgraduate researchers and collaborates on clinical trials with Pfizer, VARI-SU2C, and ASTRO. Her lab employs techniques like DNA repair assays , RNAseq , and mouse xenograft models to investigate mechanisms of action for epigenetic drugs.

• Systems Biology
• Cancer Research
• Drug Resistance
• +۷ مورد دیگر

Sampsa Hautaniemi is a Professor at the Department of Biochemistry and Developmental Biology within the Faculty of Medicine at the University of Helsinki. He serves as Principal Investigator of the Systems Biology of Drug Resistance in Cancer research group and holds docentship in the Faculty of Medicine. Professor Hautaniemi actively supervises doctoral students across multiple programs including the Doctoral Programme in Biomedicine, Doctoral Programme in Clinical Research, and Doctoral Programme in Integrative Life Science. His research focuses on systems biology approaches to understand drug resistance mechanisms in cancer, particularly ovarian cancer. His work integrates computational biology, genomics, epigenetics, and bioinformatics to develop precision medicine approaches for cancer treatment. His laboratory develops innovative computational methods and experimental models including patient-derived organoids to study tumor evolution, identify therapeutic targets, and predict treatment responses. Analysis of his recent publications reveals a strong emphasis on understanding tumor heterogeneity, clonal evolution during therapy, and the development of computational tools for cancer genomics. His work spans multiple disciplines including cancer biology, computational biology, immunology, and precision medicine, with a particular focus on high-grade serous ovarian cancer as a model system. Scientific Awards: The Anders Jahre Medical Prize to young medical scientists (2014) for outstanding research on systems biology and cancer The Finnish Medical Foundation 50-years jubileum award (2010) Professor Hautaniemi has supervised numerous doctoral students and early-career researchers, contributing significantly to cancer research education. His research is supported by multiple active projects including the DECIDER project (Clinical Decision via Integrating Multiple Data Levels to Overcome Chemotherapy Resistance in High-Grade Serous Ovarian Cancer) funded until 2026, as well as projects from the Academy of Finland, Cancer Foundation, and industry partners like Orion Corporation. His laboratory maintains a patient-derived organoid biobank for high-grade serous ovarian cancer and develops computational tools like Jellyfish for visualizing tumor evolution.