جست‌وجوی استاد و پژوهشگر

• Genetic Toxicology
• DNA Damage and Repair
• Apoptosis
• +۳ مورد دیگر

Assoc. Prof. Dr. Vehbi Atahan TOĞAY serves as an Associate Professor in the Department of Medical Biology at the Faculty of Medicine, Suleyman Demirel University, where he has held the position of Doctor Lecturer since 2022 after previously working as a Research Assistant from 2013 to 2022. His academic profile is anchored in extensive research on DNA damage mechanisms and toxicological assessments. Education: Licence in Biology, Suleyman Demirel University (2011) Master of Science in Medical Biology (with thesis), Suleyman Demirel University (2015) Master of Science in Biology (with thesis), Suleyman Demirel University (2019) Doctorate in Medical Biology, Suleyman Demirel University (2021) Dr. TOĞAY's research program centers on genetic toxicology, specializing in DNA damage assessment using comet assay methodology across diverse biological systems. His work investigates genotoxic effects of environmental toxins (pesticides, ochratoxin A), pharmaceutical compounds, and ionizing radiation, while simultaneously exploring protective mechanisms of natural antioxidants like astaxanthin and curcumin. This dual focus bridges molecular pathology with potential therapeutic interventions in environmental and occupational health contexts. Analysis of his 15 most recent publications reveals consistent methodological rigor in DNA damage quantification, with predominant applications in human lymphocytes, cancer cell lines (particularly breast and colon), and zebrafish models. Key thematic trends include pesticide-induced genotoxicity (thiacloprid, cyprodinil), nanoparticle-mediated apoptosis, and oxidative stress biomarkers in clinical populations including sepsis patients, gestational diabetes cases, and radiology personnel. His research demonstrates strong translational potential through collaborations with medical clinicians and environmental scientists. No scientific awards or fellowships are documented in the available records. Dr. TOĞAY has secured five competitive research grants from the Turkish Higher Education Council (YOK), serving as principal investigator on projects investigating ochratoxin A's apoptotic mechanisms, pesticide-DNA interactions, radiation-induced damage in medical personnel, and novel therapeutic development. His teaching portfolio includes Scientific Research Techniques and Ethics, Biology 1, Control of Gene Expression, and Medical Biology - Cytogenetics Application Methods, reflecting integration of research methodology with core biological concepts. His laboratory work operates within the Department of Medical Biology infrastructure, utilizing comet assay and molecular cytogenetics techniques through collaborative teams including Dilek Aşcı Çelik, Pınar Aslan Koşar, and Gülçin Yavuz Türel, with ongoing projects examining novel treatment approaches for toxin-induced pathologies.

Ken Bradyمشاهده پروفایل

استاد

• Cerebral Autoregulation Monitoring
• Pediatric Cardiac Critical Care
• Neuroprotection in Congenital Heart Disease
• +۳ مورد دیگر

Ken Brady, MD is a Professor in the Children's Heart Institute at The University of Texas Health Science Center at Houston, where he serves as Director for Post-Operative Services and Executive Director for Translational Research in Pediatric Cardiac Critical Care Medicine. As both a pediatric cardiac anesthesiologist and intensivist, Dr. Brady specializes in caring for critically ill children with heart disease in operating rooms and intensive care units. His educational background includes a BA in Neurophysiology from the University of California Berkeley, an MD from the University of California San Francisco, residency in Internal Medicine/Pediatrics at UC San Diego and Anesthesia at Johns Hopkins University, followed by fellowships in Pediatric Anesthesia and Pediatric Critical Care at Johns Hopkins University. Dr. Brady's research focuses on using engineering tools to analyze large volumes of physiologic waveforms to forecast deterioration and optimize care for critically ill children. His work centers on cerebrovascular reactivity monitoring to determine optimal blood pressure ranges for brain perfusion. Notably, his development of a cerebrovascular reactivity monitor reduced postoperative delirium odds by 45% in adult patients and is currently undergoing trials in neonates. His research spans neonatal neurodevelopment, cerebral autoregulation monitoring, and protection of vulnerable organs in critically ill children. Analysis of his recent publications reveals a strong focus on applying cerebral autoregulation monitoring across various clinical scenarios including congenital heart disease, traumatic brain injury, and neonatal critical care. His work demonstrates how physiological monitoring can predict outcomes and guide interventions to preserve neurodevelopmental potential in the most vulnerable patients. Dr. Brady is board certified by the American Board of Pediatrics (including Critical Care specialization) and the American Board of Anesthesia. His clinical and academic activities are driven by the goal of ensuring children with critical heart disease survive to reach their full developmental potential. As Director for Post-Operative Services and Executive Director for Translational Research, Dr. Brady leads initiatives that bridge laboratory discoveries with clinical applications in pediatric cardiac critical care. His work on cerebrovascular monitoring represents a significant translational research effort currently moving from adult applications to neonatal trials.