جست‌وجوی استاد و پژوهشگر

• Interstitial Lung Disease
• Idiopathic Pulmonary Fibrosis
• Sarcoidosis
• +۵ مورد دیگر

Mary Beth Scholand, MD is an Associate Professor in the Department of Internal Medicine at the University of Utah School of Medicine, specializing in Pulmonary Medicine. She serves as Director of the Interstitial Lung Disease Clinic at University of Utah Hospital and provides clinical care across multiple University of Utah Health locations including Farmington, South Jordan, Sugar House, and University Hospital. Her educational background includes: B.S. from Northwestern University M.D. from Washington University Internal Medicine Internship and Residency at Barnes Hospital Pulmonary Medicine Fellowship at University of Utah School of Medicine Dr. Scholand's research centers on interstitial lung diseases, with primary focus on idiopathic pulmonary fibrosis (IPF), sarcoidosis, and autoimmune lung diseases. She investigates genetic and phenotypic factors in chronic obstructive pulmonary disease (COPD) and interstitial lung diseases (ILD), while leading clinical trials targeting IPF cures and novel monitoring programs. Her work bridges pulmonary medicine, rheumatology, and oncology through translational research. Analysis of her 15 most recent publications reveals dominant themes in ILD therapeutics, clinical guideline development, and international registry studies. Key trends include antifibrotic drug trials (bexotegrast, pirfenidone), multidisciplinary management frameworks for autoimmune-related ILD, and pandemic-era adaptations in sarcoidosis care. Her research consistently addresses diagnostic challenges, therapeutic innovations, and patient-centered outcomes across pulmonary subspecialties. As Director of the Interstitial Lung Disease Clinic, Dr. Scholand leads a multidisciplinary team managing complex cases through integrated diagnostics and personalized treatment plans. Her clinical trials portfolio demonstrates active grant funding for therapeutic innovations in IPF and ILD, while her guideline contributions to ACR/CHEST and ATS reflect leadership in standardizing global care practices. Patient testimonials consistently highlight her expertise, thoroughness, and compassionate bedside manner, with a 4.9/5 rating from over 457 reviews.

Matthew Torresمشاهده پروفایل

دانشیار

• Post-translational modifications (PTMs)
• G protein signaling
• Mass spectrometry-based proteomics
• +۳ مورد دیگر

Dr. Matthew Torres is an Associate Professor of Biological Sciences at the Georgia Institute of Technology and an Adjunct Faculty member. He leads the Torres Lab , where his team integrates mass spectrometry , bioinformatics , and yeast genetics to decode how post-translational modifications (PTMs) regulate G protein and MAP-Kinase signaling systems. His work spans from developing machine learning tools like SAPH-ire for PTM prediction to experimental validation of PTM roles in stress adaptation and signal transduction. Education: B.S. in Biology, Humboldt State University (1997) Ph.D. in Biochemistry, University of North Carolina at Chapel Hill (2007) Research Interests: His lab focuses on four major areas: Coordinated PTM-based regulation of dynamic signaling complexes Identification of novel signaling PTMs PTM networks in stress adaptation Technology development for regulatory PTM detection Scientific Awards: K99/R00 NIH Pathway to Independence Award (2010–2016) IBB Above and Beyond Award (2016) ASPET Early Career Award (2022) Lab and Mentorship: Dr. Torres has mentored over 20 graduate students and postdocs, many of whom have gone on to prestigious positions at institutions like Genentech, UCSF, MD Anderson, and Harvard. His lab is also involved in outreach programs including Project ENGAGES for high school students and science education for elementary and middle schools. Research Tools and Facilities: He is co-director of the Systems Mass Spectrometry Core (SYMS-C) at Georgia Tech, which supports advanced proteomics research across the university.

Sharon Campbellمشاهده پروفایل

استاد

• Structural Biology
• Biochemistry
• Biophysics
• +۶ مورد دیگر

Dr. Sharon Campbell is a Gary F. Liebscher Distinguished Professor of Biochemistry and Biophysics at the UNC School of Medicine, University of North Carolina at Chapel Hill, and a member of the UNC Lineberger Comprehensive Cancer Center. Her research focuses on structural and functional studies of RAS oncoproteins, RAS superfamily members, heterotrimeric GTPases, and cell adhesion proteins vinculin/metavinculin, linking their regulation to cancer, cardiovascular, and neurological disorders. Education : PhD, MS in Biochemistry/Biophysics Key Methods : Multidisciplinary structural (X-ray, NMR, computational), biophysical, biochemical, and cell biology approaches Research Interests include: Elucidating RAS/GTPase recognition by regulatory proteins and effectors Investigating how mutations/post-translational modifications alter GTPase activity Identifying inhibitors for aberrant GTPase functions in disease Understanding vinculin-actin force-dependent 'catch bonds' in cell adhesion Exploring RAS protein radical-based regulation by reactive species Recent Article Trends span structural biology, redox signaling, GTPase dynamics, and cancer mechanisms, with subfields like RAS isoform specificity, ubiquitination, mechanobiology, and platinum drug interactions. Scientific Awards : 2023: OGE Mentoring Award 2014: Battle Distinguished Cancer Research Award 2001: Hettleman Award 1998: Jefferson-Pilot Award Advising highlights mentorship of students securing positions at Eli Lilly and receiving prestigious fellowships. Lab achievements include publications in Nature , Science Signaling , and organizing symposia on RAS pathobiology.

Wolfgang Bergmeierمشاهده پروفایل

استاد

• Platelet Signaling
• Megakaryocyte Biology
• Small GTPase Signaling
• +۴ مورد دیگر

Wolfgang Bergmeier, PhD, is a Professor in the Department of Biochemistry and Biophysics at the University of North Carolina at Chapel Hill. He is a member of the UNC Lineberger Comprehensive Cancer Center and the UNC Blood Research Center, where he leads research on the signaling mechanisms regulating megakaryocyte and platelet function in health and disease. His laboratory employs a multidisciplinary approach including biochemistry, cell and molecular biology, immunology, cutting-edge microscopy, and animal models to investigate platelet biology and its implications for human disease. Dr. Bergmeier's research focuses on understanding small GTPase signaling in platelets, particularly Rap1, and its role in hemostasis, thrombosis, and cancer. His work has made significant contributions to our understanding of how platelets secure vascular integrity, how they contribute to cancer progression and treatment complications, and how platelet function can be optimized for therapeutic purposes. His laboratory has developed novel mouse models and intravital imaging platforms to study platelet function in real-time. Analysis of Dr. Bergmeier's recent publications reveals a strong focus on platelet signaling mechanisms, particularly Rap1 and other small GTPases, and their implications for hemostasis, thrombosis, and cancer. His research spans from fundamental molecular mechanisms to translational applications, including development of novel antithrombotic strategies, optimization of platelet transfusion therapy, and understanding the complex relationship between platelets and cancer progression. Dr. Bergmeier has received numerous awards including the Outstanding Investigator Award from the National Heart, Lung and Blood Institute (NIH) in 2019, the American Heart Association ATVB Special Recognition Award in Thrombosis in 2016, and the Established Investigator Award from the American Heart Association in 2014. He has served as Chair of the 9th Symposium of Hemostasis in Chapel Hill (2018) and Vice Chair of the Gordon Research Conference on the Cell Biology of Platelets and Megakaryocytes (2017). He is also an Associate Editor for the Journal of Thrombosis and Hemostasis. His laboratory actively collaborates with clinical researchers at UNC, particularly with Dr. Nigel Mackman on cancer-related platelet research and with Drs. Flick and Wolberg on the interplay of platelets and the coagulation system. The Bergmeier Lab is part of the UNC BCBP Green Lab initiative, demonstrating a commitment to sustainability in research practices.

Laura Rijnsمشاهده پروفایل

پژوهشگر ارشد

• Biomaterials
• Tissue Engineering
• Supramolecular Chemistry
• +۳ مورد دیگر

Laura Rijns is a Postdoctoral Fellow at Stanford University co-advised by Professors Zhenan Bao and Karl Deisseroth, developing innovative (opto)genetic, electrical, and chemical tools for neural modulation in vitro and in vivo. Her work bridges biomaterials engineering with neuroscience to create next-generation platforms for cellular and tissue engineering. Education PhD in Biomedical Engineering, cum laude (2023), Eindhoven University of Technology (TU/e), Netherlands, under Professors Patricia Dankers and E.W. (Bert) Meijer, focusing on supramolecular hydrogels as extracellular matrix mimics for organoid development. MSc in Biomedical Engineering (2019), Eindhoven University of Technology (TU/e), researching supramolecular assemblies in Professor Meijer's laboratory. BSc in Biomedical Engineering (2017), Eindhoven University of Technology (TU/e). Her research centers on designing dynamic supramolecular hydrogels that replicate extracellular matrix complexity to control cellular behavior. Key interests include tunable mechanical properties for mechanobiology studies, ligand presentation strategies for directing cell polarity, and engineering biomaterials for renal organoid development and neural interfaces. She integrates principles from polymer chemistry, cell biology, and bioengineering to create responsive platforms that bridge synthetic materials with biological systems, with particular emphasis on translating fundamental material properties into functional tissue engineering outcomes. Analysis of her 15 most recent publications (2021-2024) reveals a cohesive research trajectory focused on supramolecular hydrogels for tissue engineering. Dominant themes include stress-stiffening mechanics, cell-adhesive motif engineering, and dynamic control of hydrogel-cell interactions. Her work demonstrates consistent innovation in renal tissue models (glomerulogenesis, tubulogenesis) and neural applications, with increasing sophistication in material design—from basic supramolecular polymers to multi-dynamic systems that mimic extracellular complexity. This progression highlights her unique interdisciplinary approach combining biomaterials science with regenerative medicine. No scientific awards were documented in the provided materials. Laura has no listed advisees or grant funding in the available information. She operates within Stanford's collaborative ecosystem, leveraging resources from both Professor Bao's chemical engineering lab (focusing on biomaterials and electronics) and Professor Deisseroth's neuroengineering group (pioneering optogenetics), creating a powerful synergy for developing neural modulation tools.

Michael Sheetzمشاهده پروفایل

استاد

• Mechanobiology
• Cell adhesion
• Mechanotransduction
• +۷ مورد دیگر

Michael Sheetz is a Professor at the Department of Biochemistry & Molecular Biology, University of Texas Medical Branch (UTMB Health), and Founding Director of the Mechanobiology Institute (MBI) at the National University of Singapore (NUS), where he served for 10 years as its leader. He is a key figure in mechanobiology, focusing on how cells generate and respond to forces during processes like cancer metastasis and brain function. PhD, California Institute of Technology His research explores cell adhesion , cell-substrate interactions , and mechanotransduction , with a focus on integrins, focal adhesions, and the development of tools to measure molecular-level forces. Recent studies involve integrin clustering, membrane mechanics, and the role of proteins like FHL2 and HER2 in mechanosensing. Recent publications highlight advances in nanopatterning for cell-matrix studies, biophysical modeling of adhesion dynamics, and signaling feedback mechanisms in receptor networks. His work bridges cell biology , materials science , and biophysics . Lab Members: Kashish Jain (PhD Student)

Olaf Bodamerمشاهده پروفایل

دانشیار

• Clinical Genetics
• Biochemical Genetics
• Translational Medicine
• +۱۲ مورد دیگر

Dr. Olaf Bodamer is Associate Chief for Genetics and Genomics at Boston Children's Hospital and faculty at Harvard Medical School. He leads a translational research laboratory focused on rare genetic disorders, including Kabuki syndrome and lysosomal storage diseases. He directs the Boston Children’s Lysosomal Storage Disease (BoLD) Program and the Roya Kabuki Program. MD, University of Heidelberg, Germany (1989) PhD, University of Saarland, Germany Pediatric Residency, Great Ormond Street Hospital, London Fellowship in Clinical and Biochemical Genetics, Baylor College of Medicine, USA Dr. Bodamer's research integrates systems biology and multi-omics to understand disease mechanisms and improve diagnostics. His work spans newborn screening, exome sequencing, metabolomics, and animal models. He focuses on phenotype expansion, biomarker discovery, and therapeutic development for rare diseases, particularly those affecting neurodevelopment and metabolism. His recent publications highlight trends in precision medicine, undiagnosed diseases, and genotype-phenotype correlations in Kabuki and lysosomal disorders. He has contributed significantly to clinical guidelines and diagnostic protocols for rare metabolic conditions. Member, Editorial Board: Molecular Genetics and Metabolism Scientific Advisor: All Things Kabuki, OAA Director, Medical Genetics Laboratories (former, University of Miami) Dr. Bodamer mentors junior researchers and collaborates across clinical specialties. His work is supported by institutional and collaborative grants, focusing on translational applications in pediatric genetics. He has played a key role in establishing rapid diagnostic pipelines for critically ill neonates and advancing newborn screening for lysosomal disorders. He leads research teams in the Intellectual and Developmental Disabilities Research Center and the Manton Center for Orphan Disease Research, fostering interdisciplinary collaboration in rare disease research.

Richard F. Loeser, Jr.مشاهده پروفایل

استاد

• Osteoarthritis (OA) mechanisms
• Cartilage cell biology
• Redox regulation of cell signaling
• +۴ مورد دیگر

Dr. Richard F. Loeser, Jr. is the Joseph P. Archie, Jr. Eminent Professor of Medicine and Director of the UNC Thurston Arthritis Research Center at the University of North Carolina School of Medicine. His research focuses on osteoarthritis (OA) mechanisms, particularly the role of oxidative stress, aging, and cellular signaling in joint degeneration. He has pioneered studies on redox regulation of chondrocyte signaling and integrin function, using both in vitro and rodent models. Education: Undergraduate: Virginia Tech Medical School: West Virginia University Residency/Fellowship: Wake Forest Baptist Medical Center Research interests include OA biomarkers, exercise interventions, and gut microbiota's role in joint health. His clinical work emphasizes translating basic science discoveries into therapeutic strategies, including weight loss and exercise programs for knee OA patients. He leads multidisciplinary teams studying OA phenotypes and metabolomics. Publications reflect a blend of clinical trials (e.g., START trial on strength training) and mechanistic studies on cellular senescence and Sirt6 pathways. He holds leadership roles in arthritis research and has contributed to major reviews defining OA as a systemic joint disease.

Christine F. Wildsoetمشاهده پروفایل

استاد

• Myopia research
• Refractive development
• Eye growth regulation
• +۴ مورد دیگر

Christine F. Wildsoet is a Professor of Optometry and Vision Science at the School of Optometry, University of California, Berkeley. Her research focuses on eye growth regulation, refractive development, and myopia, utilizing molecular biology, neurobiology, and advanced imaging techniques. School of Optometry, University of California, Berkeley Center for Eye Disease and Development NEI Summer Research Training Program Director, Oxyopia Seminars Her research addresses the complex etiology of myopia, integrating genetic and environmental factors, with implications for public health. She employs animal models, particularly chicks, to study visual experience, defocus signaling, and ocular growth mechanisms. Recent publications highlight applications of bioengineering and molecular profiling in myopia research, including studies on scleral gene expression, choroidal responses to defocus, and optical interventions. Collaborations span national and international institutions in myopia and ocular health domains. Teaching includes Optometry 226: Systemic Disease and Optometry 236: Ocular Manifestations of Systemic Disease , emphasizing pathophysiology, pharmacology, and clinical management. Labs/teams: UC Berkeley Myopia Research Group Center for Eye Disease and Development

Francesco Dell'Accioمشاهده پروفایل

استاد

• Regenerative Medicine
• Osteoarthritis
• Cartilage Biology
• +۳ مورد دیگر

Professor Francesco Dell’Accio is a clinical rheumatologist and scientist at Queen Mary University of London, affiliated with the William Harvey Research Institute (Faculty of Medicine and Dentistry) and the Department of Experimental Medicine & Rheumatology. His research focuses on regenerative medicine and osteoarthritis, with a particular emphasis on understanding molecular mechanisms underlying cartilage repair and identifying therapeutic targets. He leads a multidisciplinary team investigating signaling pathways in cartilage injury and disease progression, aiming to develop pharmacological interventions to restore cartilage integrity and alleviate osteoarthritis pain. His research group includes senior members like Prof. Shafaq Sikandar and Dr. Suzanne Eldridge, as well as postdoctoral researchers and PhD students such as Aida Barawi, Sabah Bharde, and Melody Deniz. Collaborations span institutions like Oxford, Harvard, and international partners in Germany and Scotland. Funding sources include Versus Arthritis, the Medical Research Council, and industry partners like UCB. Key research themes include the role of agrin in cartilage regeneration, ROR2 signaling blockade for osteoarthritis therapy, and neutrophil-derived extracellular vesicles in joint protection. His work integrates molecular biology, preclinical models, and clinical translation, with a focus on pain mechanisms and disease-modifying osteoarthritis drugs (DMOADs). The ReGen Lab (@TheReGenLab) is at the forefront of developing novel strategies to address cartilage defects and arthritis-related pain.

Jung Hwan Kimمشاهده پروفایل

استادیار

• Cell Biology
• Neuroscience
• Molecular Biology
• +۳ مورد دیگر

Jung Hwan Kim is an Assistant Professor in the Department of Biology at the University of Nevada, Reno . He earned his Ph.D. in Life Science from Pohang University of Science and Technology (2015) and conducted postdoctoral training at the University of Michigan, Ann Arbor . Education Ph.D., Life Science, Pohang University of Science and Technology (2015) M.S., Life Science, Pohang University of Science and Technology (2000) B.S., Agricultural Chemistry, Korea University (1998) Research Interests focus on cell biology of the nervous system , including mechanisms of subcellular protein localization in axonal development and the molecular roles of yippee-like genes in synapse formation. His lab employs Drosophila (fruit flies) as a model system with advanced genetics and biochemical techniques. Publications highlight work on dual leucine zipper kinase , Dscam expression , and synaptic circuit regulation , with recent studies on Rab11-mediated stress signaling suppression and YPEL3 mutations affecting sensory circuits. Teaching includes courses like BIOL 315 - Cell Biology and BIOL 395 - Laboratory in Genetics and Cell Biology .

• Mathematical Biology
• Cell Mechanics
• Cytoskeleton Dynamics
• +۴ مورد دیگر

Angelika Manhart is an Assistant Professor in the Department of Mathematics at the University of Vienna's Faculty of Mathematics. With 26 publications spanning from 2014 to 2025, she has established herself as a leading researcher at the intersection of mathematical modeling and biological processes. Her work bridges rigorous mathematical analysis with biological insight to address fundamental questions in cellular mechanics and dynamics. Dr. Manhart's research focuses on mathematical biology, particularly the mechanics of cellular processes including cell movement, cytoskeletal dynamics, and tissue morphogenesis. She specializes in developing computational frameworks that capture the intricate interplay between physical forces and biological functions at the cellular level. Her work explores how mathematical models can elucidate complex phenomena such as actin network dynamics, nuclear positioning in muscle cells, and epithelial tissue formation. She employs techniques from partial differential equations, dynamical systems theory, and computational mathematics to address biological questions across multiple scales. Her publication record reveals a consistent trajectory of increasingly sophisticated modeling approaches, with recent work incorporating machine learning techniques and multiscale modeling. The research spans diverse biological contexts including wound healing, muscle development, microbial communities, and epithelial morphogenesis, demonstrating the versatility of mathematical approaches in biological inquiry. Several of her papers have received significant citations, with 'Nuclear Scaling Is Coordinated among Individual Nuclei in Multinucleated Muscle Fibers' (2019) accumulating 49 citations and 'Intracellular Fluid Mechanics: Coupling Cytoplasmic Flow with Active Cytoskeletal Gel' (2018) receiving 83 citations. Dr. Manhart actively collaborates with experimental biologists across institutions, as evidenced by her co-authorship with researchers from various biological disciplines. Her work has been presented at conferences including talks on 'Alignment processes in cells - From individual interactions to collectivity' (December 2024) and earlier presentations on 'Model and Simulation of Actin-dependent Cell Movement' (2014), reflecting her continued engagement with both theoretical and applied aspects of her field.

Juan Valle Delgadoمشاهده پروفایل

مدرس

• Nanotechnology
• Biomaterials
• Surface Chemistry
• +۷ مورد دیگر

Juan Valle Delgado is a Lecturer in the Department of Bioproducts and Biosystems at Aalto University, where he focuses on nanotechnology, biomaterials, and interfacial science. His research explores sustainable materials derived from biopolymers like cellulose and lignin, with applications in biomedicine, green chemistry, and advanced composites. Research Interests: Dr. Delgado's work spans atomic force microscopy, nanocellulose functionalization, colloidal systems, and surface chemistry. Key themes include: Design of lignin nanoparticles for drug delivery and 3D bioprinting Cellulose nanofibril hydrogels for biomedical applications Interfacial interactions in bio-based composites Surface modification techniques for sustainable materials His recent publications (2019–2023) demonstrate a strong emphasis on biomaterial interfaces , with recurring studies on cellulose-lignin systems, nanoparticle synthesis, and cell-biomaterial interactions. Collaborative projects frequently involve tissue engineering, cancer research, and green nanotechnology. Dr. Delgado collaborates extensively with the Bioproduct Chemistry research group, focusing on interdisciplinary approaches to develop functional materials from renewable resources.

Timothy R Zacharewskiمشاهده پروفایل

استاد

• Nuclear Receptor-mediated Toxicity
• Gene Expression Regulation
• Environmental Toxicology
• +۶ مورد دیگر

Timothy R Zacharewski is a Professor at the Department of Biochemistry & Molecular Biology at Michigan State University, affiliated with the Genetics & Genome Sciences Program and Cell & Molecular Biology Program. His research focuses on nuclear receptor-mediated toxicity, particularly how environmental chemicals, drugs, and natural products affect gene expression in the liver and endocrine system. Ph.D. (1990) - Texas A&M University B.S. (1986) - University of Guelph Using in vivo rodent and in vitro cell line models, he compares human, mouse, and rat responses to reduce cross-species extrapolation uncertainties. His work integrates toxicology, genomics, and computational approaches to study mechanisms like coagulation-driven fibrosis, pyruvate kinase isoform switching, and circadian rhythm disruption linked to TCDD exposure. Recent publications highlight aryl hydrocarbon receptor pathways , metabolic reprogramming , and cross-species gene expression comparisons in mouse models. The lab employs bioinformatics and multi-omics analyses (lipidomics, transcriptomics) to explore environmental contaminant impacts on bile acid homeostasis, antibiotic resistance gene reservoirs, and REV-ERBα/β activation in hepatotoxicity. Professor Zacharewski's research has significant implications for understanding human risk from xenobiotic exposures and improving toxicity modeling frameworks.

Jianhua Ruanمشاهده پروفایل

استاد

• Bioinformatics
• Computational Systems Biology
• Machine Learning for Life Sciences
• +۷ مورد دیگر

Dr. Jianhua Ruan is a Professor in the Department of Computer Science at The University of Texas at San Antonio (UTSA), affiliated with the College of Sciences. He holds a Ph.D. in Computer Science from Washington University in St. Louis and has been a faculty member at UTSA since 2007. His research focuses on bioinformatics, computational systems biology, and machine learning applied to life sciences. Specific areas include modeling cis-regulatory networks, analyzing biological networks via graph algorithms, and biomarker discovery using omics data. Dr. Ruan collaborates extensively with biologists at UTSA and the UT Health Science Center on genomic, transcriptomic, proteomic, and epigenomic studies. Key research interests include: Machine learning for cis-regulatory network modeling Graph algorithms for biological network analysis Integrated omics data analysis for disease prediction Epigenetic regulation and cancer biology His work has been supported by NIH, NSF, and the San Antonio Life Sciences Institute. Notable achievements include a Best Performer award in the DREAM Reverse Engineering Challenges (2008) and the UTSA Faculty Research Award (2007). Dr. Ruan organizes the UTSA Computer Science Graduate Research Seminar, fostering interdisciplinary collaboration. He has developed software tools like TSCAN for single-cell RNA-seq analysis and contributes to computational methods for biomarker discovery and network-based classification.