جست‌وجوی استاد و پژوهشگر

Harris H. Wangمشاهده پروفایل

دانشیار

• Systems Biology
• Synthetic Biology
• Genome Engineering
• +۱۷ مورد دیگر

Harris H. Wang is an Associate Professor in the Department of Systems Biology and Department of Pathology and Cell Biology at Columbia University's Vagelos College of Physicians and Surgeons, where he also serves as Interim Chair of Systems Biology. He is affiliated with the Center for Computational Biology and Bioinformatics (C2B2) and the Integrated Program in Cellular, Molecular and Biomedical Studies (CMBS). B.S., Physics and Mathematics, MIT Ph.D., Biophysics, Harvard University Dr. Wang's research lies at the intersection of systems and synthetic biology, focusing on developing foundational technologies for genome engineering, microbiome manipulation, and synthetic genomics. His lab pioneers methods such as MAGE, MAGIC, CAST, and CAMII to enable high-throughput genetic manipulation, in situ microbiome engineering, and AI-driven microbial culturomics. Key research themes include understanding microbial community dynamics, engineering cellular memory systems, designing biocontained genetic circuits, and applying synthetic biology to human health challenges in personalized medicine and infectious disease. His recent publications reveal a strong trend in spatial and functional metagenomics, CRISPR-based microbiome editing, and synthetic biology tools for data storage and genetic stability. The articles span high-impact journals like Nature , Science , and Nature Biotechnology , reflecting his leadership in developing scalable, programmable biological systems. Scientific Awards: NIH Director’s Early Independence Award Forbes 30 Under 30 in Science Sloan Research Fellowship NSF CAREER Award ONR Young Investigator Award Burroughs Wellcome Fund PATH Award Schaefer Scholar Blavatnik National Award Vilcek Prize PECASE Dr. Wang has advised numerous PhD and postdoctoral researchers, many of whom have gone on to independent scientific careers. His lab is supported by major grants from NIH, NSF, DARPA, DOE, and foundations including the Bill & Melinda Gates Foundation and CZ Biohub NY. He is actively involved in educational initiatives, including organizing Columbia’s iGEM team and the Cold Spring Harbor Laboratory Synthetic Biology course. The Wang Lab is based at the Columbia University Irving Medical Center and is part of national consortia such as the Engineering Biology Research Consortium (EBRC) and the Genome Project-Write (GP-Write) initiative. The lab develops and applies cutting-edge technologies in automation, machine learning, and synthetic biology to engineer microbiomes for applications in medicine, global health, and climate change.

Peter Bühlmannمشاهده پروفایل

استاد

• High-dimensional Statistics
• Causal Inference
• Machine Learning
• +۳ مورد دیگر

Peter Bühlmann is a Professor at ETH Zürich within the Seminar für Statistik , focusing on high-dimensional statistics, causal inference, and machine learning. His work bridges theoretical advancements with practical software implementations in R packages like pcalg , mboost , and glmmlasso , impacting fields such as genomics, proteomics, and intensive care analytics. Key Contributions : Causal structure learning, stability selection, anchor regression, and deconfounding. Software : Developed widely used R packages for statistical modeling and causal inference. Teaching : Courses on high-dimensional statistics at ETH Zürich and international institutions. Research Trends : Recent articles emphasize causal robustness, domain adaptation, and applications in medicine. His work addresses challenges in heterogeneous data, missing values, and covariate shifts using methods like spectral deconfounding and residual prediction tests. Scientific Recognition : Co-author of a paper designated as a New Hot Paper (Meinshausen and Bühlmann, 2006) by Essential Science Indicators, indicating significant impact in high-dimensional multiple testing.

Daniel Cooneyمشاهده پروفایل

استادیار

• Mathematical Biology
• Applied Dynamical Systems
• Differential Equations
• +۴ مورد دیگر

Daniel Cooney is an Assistant Professor in the Department of Mathematics at the University of Illinois Urbana-Champaign. He holds additional affiliations as an Affiliate at the Carl R. Woese Institute for Genomic Biology. His research focuses on applying partial differential equations (PDEs), dynamical systems, and stochastic processes to study evolutionary dynamics, particularly in biological and social systems. Key themes include multilevel selection, evolutionary game theory, and the emergence of cooperative behavior. Cooney earned his PhD in Applied and Computational Mathematics from Princeton University, advised by Simon Levin, and completed a postdoc as a Simons Fellow in Mathematical Biology at the University of Pennsylvania. His work bridges theoretical mathematics with applications in ecology, epidemiology, and social sciences. Recent publications explore topics like altruistic punishment in cultural systems, classroom-turnover dynamics, and protocell evolution. He actively participates in academic outreach, co-organizing conferences such as the AMS Special Session on Mathematics of Infectious Disease and the SIAM Minisymposium on Social-Ecological Systems. His research has been published in high-impact journals including *Proceedings of the National Academy of Sciences* and *Bulletin of Mathematical Biology*.

Yaojun Zhangمشاهده پروفایل

استادیار

• Biological Physics
• Biophysics
• Theoretical Physics
• +۳ مورد دیگر

Yaojun Zhang is an Assistant Professor in the Department of Physics & Astronomy and the Department of Biophysics at Johns Hopkins University. She earned her PhD in Physics from the University of California, San Diego (2015), followed by postdoctoral fellowships at the Princeton Center for Theoretical Science (2015-2018) and the Princeton Center for the Physics of Biological Function (2018-2021). Her research focuses on biological physics, particularly the complex behaviors of biomolecules and their assemblies across scales—from single-molecule folding to intracellular transport and biomolecular phase separation. She employs theoretical, mathematical, and computational tools to bridge biological questions with physical principles. Education PhD in Physics, University of California, San Diego (2015) Postdoctoral Fellowships: Princeton University (2015-2021) Research Interests Her group studies biomolecular condensates and liquid-liquid phase separation, exploring how microscopic interactions determine macroscopic properties of cellular compartments. Key areas include: Biomolecular condensate formation and dynamics Phase separation in cellular environments Interactions between biomolecules and cellular components Biophysics of intracellular transport Collaborations & Tools Zhang collaborates with experimentalists to validate theoretical models and develops frameworks for understanding condensate functions, such as surface tension, stoichiometry, and phase diagrams. Her work addresses challenges like condensate stability, molecular exclusion, and biological function regulation. Labs & Resources She leads the Zhang Lab , which integrates experimental and computational approaches. Her team’s research is supported by resources at the Bloomberg Center for Physics and Astronomy.

• Synthetic Biology
• Systems Biology
• Quantitative Biology
• +۵ مورد دیگر

Ting Lu is an Associate Professor at the University of Illinois at Urbana-Champaign in the School of Biomedical and Translational Sciences, focusing on microbial synthetic biology and systems biology. Their research bridges biology, engineering, and physics to reprogram cellular functionalities through gene regulatory networks. Ph.D. in Biophysics, University of California at San Diego (2007) B.S. in Physics, Zhejiang University (2002) Ting Lu's work explores microbial ecosystems, synthetic gene circuits, and their applications in biotechnology and medicine. By combining experimental approaches with mathematical modeling, they investigate bacterial communication networks, metabolic pathways, and spatial dynamics in microbial communities. Selected research trends include microbial consortia engineering for bioremediation and bioproduction, complexity reduction in microbiomes, and predictive modeling of synthetic gene networks. Their publications span high-impact journals such as Nature Communications , Nature Chemical Biology , and eLife . Fellow, American Institute for Medical and Biological Engineering (2022) Future Insight Prize (2021) Donald Biggar Willett Faculty Scholar (UIUC) (2020) NIH Maximizing Investigators' Research Award (2019) NSF CAREER Award (2015) AHA National Scientist Development Grant (2012) Ting Lu's lab has received grants from NIH, NSF, ONR, and industry partners. They offer undergraduate research opportunities in synthetic and systems biology, and teach advanced courses such as BIOE 430 - Intro Synthetic Biology and BIOE 432 - Systems Biology .

• RNA Biology
• Myeloid Malignancies
• Hematology
• +۴ مورد دیگر

Dr. Giulia Biancon is an Assistant Professor Adjunct in the Department of Medical Oncology and Hematology at Yale School of Medicine. She holds a PhD from the University of Milan (2019) and is a member of the Halene Lab, focusing on RNA biology and hematologic malignancies. Her research combines high-throughput methodologies to study RNA mechanisms in diseases like myeloid leukemias and splicing factor mutations. Education: PhD in Molecular Biology from the University of Milan (2019). Research Interests: RNA splicing, stress granules in cancer, epitranscriptomics, clonal hematopoiesis, and the interplay between genetic mutations and cellular pathways in blood cancers. Awards: 2024 Eclipse Award, 2022 ASH Abstract Achievement Award, and 2022 RNA Society Best Poster Award. Her work has been published in journals like Cell Reports , Blood , and Molecular Cell . Labs/Teams: Principal member of the Halene Lab and coordinator at the Yale Center for RNA Science and Medicine. Collaborates with institutions like the SeroNet network for immunology studies.

• RNA Biology
• Bioinformatics
• Plant Molecular Biology
• +۴ مورد دیگر

Peter Brodersen is a Professor at the Department of Biology, University of Copenhagen , specializing in Bioinformatics and RNA Biology . His research focuses on RNA modification (m6A), YTHDF proteins, and small RNA pathways in plants. Recent research trends from his group include: (1) molecular mechanisms of ARGONAUTE-small RNA interactions, (2) m6A-YTHDF regulatory systems in plant development, and (3) RNAi-independent roles of DICER-LIKE proteins in antiviral defense. Collaborations span Denmark and international institutions. Publications highlight cross-disciplinary work bridging computational biology and experimental plant genetics. Key subfields include RNA structure, epigenetic regulation, and antiviral immunity.

Christopher Kananمشاهده پروفایل

دانشیار

• Artificial Intelligence
• Deep Learning
• Continual Learning
• +۵ مورد دیگر

Christopher Kanan is a tenured Associate Professor of Computer Science at the University of Rochester, leading the AI Initiative within the Hajim School of Engineering & Applied Sciences. He holds secondary appointments in Brain and Cognitive Sciences, the Goergen Institute for Data Science and AI (GIDS-AI), and the Center for Visual Science. His research focuses on deep learning systems for artificial general intelligence (AGI), including continual learning, medical computer vision, and visual question answering. Previously, he was an Associate Professor at RIT’s Carlson Center for Imaging Science and a leader at Paige.AI, contributing to the FDA-cleared Paige Prostate system. Kanan earned his PhD from UC San Diego, completed postdoctoral work at Caltech, and worked at NASA JPL. Education: PhD in Computer Science, UC San Diego MS in Computer Science, University of Southern California Bachelor’s in Philosophy and Computer Science, Oklahoma State University Research Interests: Kanan’s work spans foundational AI capabilities like continual learning, medical imaging (pathology and radiology), multi-modal reasoning, and cognitive science-inspired models. His lab develops bias-robust AI systems and applies deep learning to healthcare and fusion research. Articles Trends: His recent work emphasizes out-of-distribution generalization, foundation models in pathology, and stability in continual learning. Key themes include AI applications in healthcare, model robustness, and neuroscience-inspired algorithms. Awards: NSF CAREER Award Senior Member, AAAI and IEEE DoE and NSF grants totaling $5M+ DARPA/ARL awards Advising & Grants: Mentored over 10 PhD students, including Robik Shrestha and Usman Mahmood. Secured grants for AI in nuclear fusion and medical imaging. Led RIT’s Center for Human-aware AI (CHAI) as Associate Director. Labs & Teams: Heads the University of Rochester AI Initiative, collaborates with Paige.AI, and leads teams advancing AI in pathology and robotics. His lab’s KLab (klab.cis.rit.edu) focuses on vision and learning systems.

Kristian Helinمشاهده پروفایل

استاد

• Cancer biology
• Epigenetics
• Stem cells
• +۵ مورد دیگر

Kristian Helin is Chief Executive and President of The Institute of Cancer Research (ICR), London, and a Professor with affiliations at the University of Copenhagen and Memorial Sloan Kettering Cancer Center. He founded/directed the Biotech Research & Innovation Centre (BRIC), Centre for Epigenetics, and Danish Stem Cell Center. His research focuses on epigenetic regulation, cancer biology, and stem cell differentiation. Education: Ph.D. Molecular Biology, University of Copenhagen (1991) M.Sc. Chemical Engineering, Technical University of Denmark (1988) Research Interests: Helin's work deciphers molecular mechanisms in cancer, emphasizing epigenetic drivers (e.g., H3K4/H3K36 methylation), transcriptional control, and therapeutic targeting. His lab identified E2F transcription factors, linked epigenetic dysregulation to leukemia/lymphoma, and develops drugs targeting kinases/epigenetic enzymes. Research spans acute myeloid leukemia, B-cell lymphoma, and solid tumors using CRISPR screens and preclinical models. Publication Trends: Recent articles (2023-2025) focus on epigenetic therapy, chromatin remodeling, and kinase signaling in cancer. Key themes include targeting NSD1/KDM5C/RIOK2 enzymes, combination therapies (EZH2/DOT1L inhibitors), and metabolic regulation in leukemia. Studies bridge basic mechanisms (enhancer regulation, insulator accessibility) with translational applications. Awards: Anders Jahre Prize (2014), ERC Advanced Grant (2011), Novo Nordisk Prize (2008) Memberships: Academia Europaea, Royal Danish Academy, EMBO Leadership: Helin co-founded EpiTherapeutics (acquired by Gilead) and leads the Epigenetics and Cancer lab at ICR. His team investigates AML pathogenesis and chromatin complexes like HUSH/NURF. Grants include ERC funding and innovation prizes.

Vakil Takhaveevمشاهده پروفایل

مدرس

• DNA Damage and Repair
• Aging Mechanisms
• Cancer Biology
• +۶ مورد دیگر

Dr. Vakil Takhaveev is a Lecturer at ETH Zurich's Department of Health Sciences and Technology, within the Institute of Food, Nutrition and Health. His research focuses on DNA damage mechanisms, aging, cancer, and neurodegeneration, with particular emphasis on developing novel DNA-damage-sequencing methods like click-code-seq and TRABI-Seq . He investigates anticancer drug action (e.g., trabectedin), aging clocks using DNA oxidation profiling, and stress-induced carcinogenesis. His work integrates multi-omics approaches and advanced sequencing techniques. Research Directions: Novel DNA-Damage-Sequencing Methods: Developed click-code-seq and TRABI-Seq for genomic mapping of DNA lesions and repair dynamics. Anticancer Drug Action: Explored mechanisms of trabectedin and other chemotherapeutics, linking DNA repair vulnerabilities to therapy resistance. Aging Clocks: Created DNA oxidation-based biomarkers for biological aging using genome-wide profiling in human and mouse models. Stress-Induced Pathologies: Studies metabolic and DNA damage links to early tumorigenesis and neurodegeneration. Awards & Recognition: 2025 Public Award Winner in PIs of Tomorrow competition 2024 ETH Zurich Career Seed Award Best presentation awards (Swiss Chemical Society, American Chemical Society) Grants & Collaborations: Impetus grants for aging clock development Swiss Chemical Society and American Chemical Society fellowships Labs & Teams: Leads research on DNA damage and aging mechanisms at ETH Zurich, collaborating with international groups in oncology and toxicology.

Anthony Rollettمشاهده پروفایل

استاد

• Additive Manufacturing
• Advanced Materials Processing and Manufacturing
• Digital Twins
• +۶ مورد دیگر

Anthony Rollett is a Professor in the Department of Materials Science and Engineering at Carnegie Mellon University , where he has been a faculty member since 1995. He serves as the Principal Investigator and Co-Director of the NASA-supported Institute for Model-Based Qualification & Certification of Additive Manufacturing (IMQCAM) and co-director of the Next Manufacturing Center . Prior to CMU, he held leadership roles at Los Alamos National Laboratory (1991-1995). Education: Ph.D., Materials Engineering, Drexel University (1987) MA, Metallurgy and Materials Science, Cambridge University (1977) Research Interests: Rollett’s work focuses on microstructural evolution and microstructure-property relationships in 3D using experiments and simulations. His expertise spans additive manufacturing , metal 3D printing , materials for energy systems , grain growth , recrystallization , and stereology , with techniques like high-energy diffraction microscopy (HEDM) and dynamic x-ray radiography (DXR) . Scientific Contributions: He has over 320 peer-reviewed publications and an h-index >80 . His recent articles highlight machine learning for laser processing , fatigue analysis of additively manufactured alloys, and design optimization for heat exchangers in supercritical CO2 and solar thermal applications . Scientific Awards: Fellow of ASM International (1996) Fellow of the Institute of Physics (UK) (2004) Fellow of The Minerals, Metals & Materials Society (TMS) (2011) Cyril Stanley Smith Award (TMS, 2014) Member of Honor, French Metallurgical Society (2015) US Steel Professor (2017) Francqui International Professor (2020-2021) International FAME Award (2023) Leadership & Impact: Rollett co-led the development of a NASA Space Technology Research Institute for additive manufacturing and established a new master’s program in additive manufacturing (2018). His research group is funded by industry , federal agencies , and Pennsylvania state grants . He also serves on the Basic Energy Science Advisory Committee and Defense Programs Advisory Committee for the Department of Energy.

Britt Adamsonمشاهده پروفایل

دانشیار

• Stress Response Networks
• DNA Damage Response
• Genome Editing
• +۳ مورد دیگر

Britt Adamson is an Associate Professor in the Department of Molecular Biology and the Lewis-Sigler Institute for Integrative Genomics at Princeton University, where she serves as Director of the Undergraduate Program in Quantitative and Computational Biology. Her lab investigates molecular networks in human cells with focus on stress response mechanisms and genome editing technologies. She received her B.S. in Biology from the Massachusetts Institute of Technology (2005) and Ph.D. in Genetics and Genomics from Harvard University (2012), followed by postdoctoral training at UCSF under Jonathan Weissman supported by a Damon Runyon Cancer Research Foundation Fellowship. Adamson's research centers on how cells organize stress response networks during DNA damage and endoplasmic reticulum stress, developing CRISPR-based functional genomics and single-cell sequencing tools to map molecular behaviors. Her work bridges fundamental cell biology with therapeutic applications in genome editing. Analysis of her 15 most recent publications reveals dominant themes in precision genome editing (prime/base editing optimization) and systematic dissection of DNA repair pathways through combinatorial CRISPR screening. Her lab consistently integrates computational approaches with high-resolution experimental techniques to uncover context-dependent cellular behaviors. Her scientific recognitions include: Damon Runyon Cancer Research Foundation Postdoctoral Fellowship Princeton IP Accelerator Award (2025) STAT Who to Know: 10 Scientists leading a new generation of gene editors (2024) Adamson actively mentors eight graduate students (including alumni Ann Cirincione and Jun Hussmann) and two postdocs, with research funded through institutional awards and collaborative grants. Her lab's technological developments have enabled projects spanning virology, immunology, and developmental biology. The Adamson Lab operates within Princeton's Lewis-Sigler Institute for Integrative Genomics, fostering an interdisciplinary environment that merges cell biology, genomics, and computational science. Current projects focus on improving prime editing efficiency and understanding stress response adaptation in disease contexts.

Angela D Kentمشاهده پروفایل

استاد

• Microbial Ecology
• Nitrogen Cycling
• Agroecosystems
• +۳ مورد دیگر

Angela D. Kent is a Professor in the Department of Natural Resources and Environmental Sciences at the University of Illinois Urbana-Champaign, where she also serves as Director of the Program in Ecology, Evolution, and Conservation Biology within the School of Integrative Biology. She is affiliated with the Carl R. Woese Institute for Genomic Biology. Her research focuses on microbial communities in agroecosystems and natural environments, particularly their roles in nitrogen cycling, soil health, and sustainable bioenergy production. Key research interests include microbial interactions in plant-microbe systems, the impact of genetic variation in crops on microbial processes, and the ecological and biogeochemical implications of soil microbiomes. She has authored over 99 publications and supervised datasets on topics such as denitrification dynamics, rhizosphere microbiome assembly, and microbial contributions to nitrogen retention. Dr. Kent has received the NACTA Educator Award (2012) and has contributed to high-impact studies on topics like microbial community responses to environmental stressors and the application of stable isotopes in bioenergy research. Her work bridges microbial ecology, agronomy, and environmental science, emphasizing practical solutions for sustainable agriculture and ecosystem management.

• Microbial Genomics
• Gut Microbiome
• Aging and Healthy Aging
• +۴ مورد دیگر

Paul O'Toole is a Professor of Microbial Genomics and Principal Investigator at the APC Microbiome Ireland, University College Cork. His research focuses on the gut microbiome's role in health, aging, and disease, particularly in the context of diet and probiotics. He leads projects like the ELDERMET study on elderly nutrition and the NU-AGE project exploring Mediterranean diets' anti-aging effects. He holds a BA (Mod.) from Trinity College Dublin and a PhD from Lund University, with postdoctoral training in Canada and New Zealand. Key grants include studies on dairy-derived microbiota, probiotic strain improvement, and microbiome analysis in aging populations. He has published extensively on Lactobacillus genomics, gut-brain interactions, and microbiome-driven health outcomes. His work bridges fundamental microbiology with clinical applications, emphasizing translational research. Scientific highlights include discovering microbiome links to cognitive decline, demonstrating dietary modulation of gut microbes to combat obesity, and identifying keystone species in healthy aging. He advocates for sustainability in conservation and food systems, reflecting his interdisciplinary approach to global health challenges.

Steven G. Clarkeمشاهده پروفایل

استاد

• Biochemistry
• Systems Biology
• Biological Regulation
• +۸ مورد دیگر

Dr. Steven G. Clarke is a Distinguished Professor at UCLA Department of Chemistry & Biochemistry and director of research at the Molecular Biology Institute . His work bridges protein chemistry , methylation biology , and aging research through studies of spontaneous protein damage and its repair mechanisms. Education: BA in Chemistry and Zoology, Pomona College (magna cum laude, Phi Beta Kappa) PhD in Biochemistry and Molecular Biology, Harvard University (NSF Fellow) Postdoctoral Fellowship at UC Berkeley (Miller Fellow) Dr. Clarke's research focuses on protein isoaspartyl repair via PCMT1/PIMT enzymes , ribosomal protein methylation in Saccharomyces cerevisiae , and PRMT family characterization including PRMT7 and PRMT9. His lab combines biochemical assays , genetic models , and structural analysis to investigate aging mechanisms and disease implications. Recent publications highlight: COQ5 structure-function analysis in coenzyme Q biosynthesis PCMTD1 ubiquitin ligase interactions PRMT7 substrate specificity in histone H2B Protein isoaspartyl impacts on T cell function in lupus Novel PRMT inhibitors for cancer therapy Methionine addiction in osteosarcoma malignancy Major scientific awards: American Chemical Society Ralph F. Hirschmann Award in Peptide Chemistry NIH MERIT Award Ellison Medical Foundation Senior Scholar Award William C. Rose Award, ASBMB UCLA Distinguished Teaching Award (Eby Award winner) Current lab members include PhD candidates Eric Pang (UCSB) and Sining "Cindy" Wang (UCLA), while undergraduates Celeste Medina-Seymoure , Elizabeth Oroudjeva , Olivia Pacheco , and Jasmine Winter contribute to ongoing proteostasis studies. Collaborations with Profs. Jose Rodriguez and Catherine Clarke demonstrate interdisciplinary research approaches.