جست‌وجوی استاد و پژوهشگر

Jose Antonio Lagares Rodriguezمشاهده پروفایل

دانشیار

• Computer Science
• Data Analysis
• Artificial Intelligence
• +۳ مورد دیگر

Jose Antonio Lagares Rodriguez is an Associate Professor at the Universidad Pablo de Olavide , affiliated with the College of Sports and Information Technology . His academic work focuses on Computer Languages and Systems within the DATAi (Intelligent Data Analysis) research group, though his publication record spans interdisciplinary topics including public health, cardiology, and biomedical engineering . Key Research Themes: Integration of data analysis in healthcare systems Biochemical mechanisms in disease progression Health policy and social program evaluation Innovative applications of information technology in clinical settings Recent Work Trends: His 2015-2014 publications highlight drug development ( CM-352 ), hepatocarcinogenesis mechanisms, and immigrant health screening. Earlier works (2003-2009) cover architectural engineering, thyroid oncology, and infectious disease dynamics. Collaboration Network: He has co-authored studies with medical professionals across disciplines, including endocrinologists, epidemiologists, and materials scientists. His work has been cited 1,544 times on Academia.edu.

Barbara Cianiمشاهده پروفایل

مدرس ارشد

• Biophysical Chemistry
• Protein Self-Assembly
• Membrane Biology
• +۳ مورد دیگر

Dr. Barbara Ciani is a Senior Lecturer in Biophysical Chemistry at the University of Sheffield's School of Mathematical and Physical Sciences. She serves as the Chemistry Biological Safety Officer and is affiliated with the RSC Biophysical Chemistry Interest Group and EPSRC review college. Research Interests: Protein self-assembly mechanisms, nuclear envelope repair, ESCRT-III complex dynamics, and protein solution physical chemistry. Teaching: Thermodynamics, Biophysical Chemistry, Toxicology, Bioinformatics, and Protein Design across undergraduate and postgraduate modules. Her lab combines biochemistry, cell biology, and protein design to address membrane repair signals and protein formulation optimization with industry partners. Recent publications focus on membrane remodeling, protein-stability relationships, and disease-associated protein interactions. Collaborations span academic and industrial domains, emphasizing biomimetic applications and drug discovery science.

• Molecular and Cell Biology
• Neurodegeneration
• Inherited Retinal Dystrophies
• +۷ مورد دیگر

Mike Cheetham is a Professor of Molecular and Cell Biology at the UCL Institute of Ophthalmology, specializing in neurodegenerative disease mechanisms and therapies for inherited retinal dystrophies. His lab pioneered 3D retinal organoid models and developed an antisense therapy for LCA10 now in clinical trials. Education: PhD (University of London, 1991), BSc (University of Wales, Swansea, 1983) Research focuses on proteostasis in the nervous system, using stem cell and animal models to dissect molecular pathways in retinal dystrophies. Recent work includes gene editing for rhodopsin mutations and small molecule interventions for ciliary defects. Publications highlight advancements in CRISPRa-mediated therapies , ABCA4 variant rescue , and light-induced toxicity prevention , aligning with his expertise in molecular biology and ophthalmology. Collaborations: Extensive partnerships in gene therapy, retinal modeling, and neurodegeneration studies

Josh Huangمشاهده پروفایل

استاد

• Neuroscience
• Neurogenetics
• Developmental Neurobiology
• +۵ مورد دیگر

Josh Huang is a Professor of Neurobiology, Cell Biology, and Biomedical Engineering at Duke University School of Medicine , where he leads the Huang Lab. His research focuses on the development and function of cortical circuits underlying motor control and cognitive processing , integrating genetic engineering, single-cell genomics, and behavioral neuroscience to address neuropsychiatric disorders. Education : PhD in Neuroscience, Brandeis University (1995) Research Areas : Huang’s work spans three synergistic domains: (1) cell type genetic tools (e.g., CellREADR for RNA-programmable cell targeting), (2) molecular genetic programs defining neuronal specification, and (3) cell type basis of motor-cognitive circuits . His team employs multi-omics, optogenetics, and naturalistic behavior paradigms to decode cortical architecture. Publications highlight trends in RNA-based neurotechnology , glutamatergic/projection neuron subnetworks , and GABAergic interneuron mapping . Notable contributions include the BRAIN Initiative Cell Census Network (BICCN) and CellREADR innovations. Scientific Awards : Election to the American Academy of Arts & Sciences (2022) NIH Director’s Pioneer High-Risk High-Reward Award Grants from NIMH, NIH BRAIN Initiative, and collaborative programs support his multidisciplinary investigations . The lab trains PhD students and postdoctoral fellows in neuroscience and biomedical engineering.

Thomas G. Jensenمشاهده پروفایل

استاد

• Medical Genetics
• Gene Therapy
• Molecular Biology
• +۱ مورد دیگر

Thomas G. Jensen serves as Head of the Department of Biomedicine and Professor of Medical Genetics at Aarhus University, while also holding the position of Deputy Chairperson of the Danish Research Ethics Committee. His strategic leadership focuses on establishing the department as an internationally recognized center through impactful research, high-quality graduate education, and strengthening the local life science ecosystem. His research spans Medical Genetics , Gene Therapy , and Molecular Biology , with concentrated efforts on genetic disorders including phenylketonuria and myotonic dystrophy. His work involves developing viral vector delivery systems and investigating molecular disease mechanisms using mouse models and fibroblast cultures. Publication analysis reveals consistent contributions to translational biomedical research, particularly in gene therapy applications for metabolic and neuromuscular disorders. His work demonstrates interdisciplinary collaboration between basic science and clinical applications, with notable focus on optimizing gene delivery techniques and understanding disease pathophysiology. Professor Jensen maintains active public engagement through lectures on genetics, CRISPR technology, and research ethics for diverse audiences including patient organizations, academic institutions, and government bodies like the Danish Ethics Council.

Vivian Lee-Kimمشاهده پروفایل

استادیار

• Cardiovascular Genetics
• Vascular Biology
• Regenerative Medicine
• +۳ مورد دیگر

Vivian Lee-Kim is an Assistant Professor in the Department of Pediatrics, Division of Cardiology at The University of Texas Southwestern Medical Center, with a secondary appointment in the Department of Molecular Biology. She is also a member of the Center for Regenerative Science and Medicine. Education B.S. in Biochemistry, University of Washington Ph.D. in Developmental, Regenerative, and Stem Cell Biology, Washington University in St. Louis Postdoctoral Fellow, Brigham and Women's Hospital and Harvard Medical School Research Interests Dr. Lee-Kim's research focuses on the genetic and molecular mechanisms of cardiovascular diseases, particularly thoracic aortic aneurysms and coronary artery disease. She employs genomic approaches, CRISPR-based genome editing, and vascular biology to dissect disease pathways and identify therapeutic targets. Her work bridges basic science with clinical applications in regenerative medicine, investigating coding and noncoding genetic variations that contribute to vascular pathologies. Recent Research Trends Analysis of Dr. Lee-Kim's 13 publications (2012-2024) reveals an evolution from extracellular matrix genetics in aortic aneurysms to cutting-edge multi-omics studies of coronary artery disease. Her recent work (2020-2024) emphasizes endothelial cell programs, CRISPR perturbation screens, and functional genomics to identify novel therapeutic targets, while earlier research (2012-2016) explored mechanisms of aortic dilation and lung injury models. This trajectory demonstrates increasing integration of genomic technologies with vascular pathophysiology. Honors & Awards No specific awards are listed in the available information. Advising and Grants Information regarding student mentorship, grant funding, or research funding sources is not provided in the available text. Labs and Teams Dr. Lee-Kim is an active member of the Center for Regenerative Science and Medicine at UT Southwestern, which fosters interdisciplinary collaboration in tissue engineering, stem cell therapies, and vascular regeneration research.

David J. Andersonمشاهده پروفایل

استاد

• Neuroscience
• Neurobiology
• Neural Circuits
• +۵ مورد دیگر

David J. Anderson is the Seymour Benzer Professor of Biology at the California Institute of Technology (Caltech), serving as Director and Leadership Chair of the Tianqiao and Chrissy Chen Institute for Neuroscience. He is also a long-standing Investigator of the Howard Hughes Medical Institute (HHMI), appointed in 1989. His academic credentials include an A.B. in Biochemical Sciences from Harvard University (1978, summa cum laude) and a Ph.D. in Cell Biology from Rockefeller University (1983), where he trained with Nobel Laureate Günter Blobel. Postdoctoral training followed at Columbia University with Nobel Laureate Richard Axel. Anderson's research centers on the neurobiological basis of emotional behaviors, particularly fear, anxiety, and aggression. His lab employs mice, Drosophila, and the jellyfish Clytia hemisphaerica to dissect neural circuits using optogenetics, chemogenetics, single-cell RNA sequencing, and advanced behavioral analysis. Key discoveries include identifying aggression-controlling neurons in the hypothalamus and fear-processing microcircuits in the amygdala. Recent publications reveal a strong emphasis on decoding aggression circuits through computational modeling of neural dynamics, whole-brain imaging, and cross-species comparisons. His work integrates molecular, cellular, and systems approaches to understand how internal emotional states emerge from neural activity and influence behavior. Major scientific awards include: 2018 Edward M. Scolnick Prize in Neuroscience 2017 New York Academy of Medicine Salmon Award 2016 Perl-UNC Neuroscience Prize 2007 National Academy of Sciences election Multiple named professorships and fellowships As an HHMI Investigator since 1989 and Allen Distinguished Investigator (2010), Anderson has secured substantial research funding. He serves on the Scientific Advisory Board of the Allen Institute for Brain Science and has mentored numerous trainees. His lab develops cutting-edge tools like the Mouse Action Recognition System (MARS) for behavioral analysis. The David Anderson Lab operates as a multidisciplinary hub integrating genetics, neurophysiology, and computational methods. Current collaborations with engineering groups focus on machine vision for behavior quantification, while expanding the Clytia model to investigate primitive internal states in brainless organisms.

• Cancer Biology
• Bioinformatics
• Neurofibromatosis
• +۵ مورد دیگر

Jody Fromm Longo is an Assistant Professor at the Medical University of South Carolina (MUSC) , affiliated with the College of Medicine and Department of Pathology and Laboratory Medicine . Her research focuses on Ras-driven cancers and neurofibromatosis type 1 (NF1) , analyzing tumor suppressor mechanisms, therapeutic target discovery, and isoform-specific protein roles in neurodegenerative disease. Education: PhD in Molecular Biology and Biochemistry from University of Southern California, BS in Chemistry/Biochemistry from Purdue University, Postdoctoral Research at Harvard Medical School in Cancer Biology and Genetics. Her work integrates bioinformatics with in vitro and in vivo models to study genomic and transcriptomic profiles of cancers. Current projects investigate Ras hyperactivation , EGFR family mutations , and isoform-specific roles of NF1 and Ras proteins in central nervous system functions. Recent publications highlight her team's efforts in MPNST research , including HER3 inhibition for therapeutic applications, genetic profiling for target identification, and bioinformatics analysis of tumor suppressor pathways. Collaborative studies explore R-Ras subfamily signaling and LPAR receptor functions in MPNST progression. While specific scientific awards aren't listed, her publications demonstrate consistent contributions to oncology , neurogenetics , and targeted therapy fields. The lab employs genetically engineered mouse models and phosphoproteomic profiling to advance cancer research and therapeutic options.

• Veterinary Oncology
• Canine Cancer Research
• Molecular Pathology
• +۵ مورد دیگر

Davis Seelig is a Professor in the Department of Veterinary Clinical Sciences at the University of Minnesota's College of Veterinary Medicine, with additional affiliation at the Masonic Cancer Center. His research spans veterinary oncology, molecular pathology, and comparative medicine, focusing on translating findings between animal and human cancers. Dr. Seelig's research interests center on veterinary oncology with a particular emphasis on canine cancers including lymphoma and hemangiosarcoma. His work explores molecular subtypes, early detection methods, and comparative approaches to cancer biology. He applies advanced techniques including flow cytometry, molecular profiling, and animal models to investigate cancer mechanisms and potential therapeutic approaches. His research bridges veterinary and human medicine, contributing to the understanding of cancer across species. His publication record shows consistent output with 104 research outputs since 2006, demonstrating expertise across veterinary pathology, cancer biology, and translational medicine. Recent publications focus on machine learning applications in drug delivery, single-cell analysis of immune responses in liver cancer, and precision techniques for tissue preservation. His work demonstrates a strong translational focus, connecting veterinary clinical findings with broader cancer research implications. Dr. Seelig is actively involved in multiple significant research projects, including the Cancer Center Support Grant from the National Cancer Institute, research on canine lymphoma detection and prevention funded by the Morris Animal Foundation, and studies on molecular subtypes in canine hemangiosarcoma. He also contributes to educational initiatives like the Veterinary Summer Scholars in Comparative Medicine program. His collaborative network extends across veterinary medicine, oncology, and biomedical engineering, working with researchers investigating everything from prion diseases to advanced drug delivery systems. His work contributes to Sustainable Development Goals related to good health and well-being through cancer research and improved veterinary medical practices.

J. Geoffrey Pickeringمشاهده پروفایل

استاد

• Vascular Biology
• Cell and Molecular Basis of Cardiovascular Disease
• Smooth Muscle Cell Motility
• +۴ مورد دیگر

J. Geoffrey Pickering is a Professor at the University of Western Ontario, affiliated with the Schulich School of Medicine & Dentistry. He holds appointments in the Departments of Medicine, Biochemistry, and Medical Biophysics. His research focuses on vascular biology, particularly the molecular mechanisms of vascular smooth muscle cell behavior, extracellular matrix interactions, and angiogenesis. Education: M.D. from Queen's University, Ph.D. in Medical Biophysics from University of Western Ontario Certifications: Fellowship in Internal Medicine and Cardiology (FRCP(C)) Key Research Areas: Vascular cell aging, endothelial-mesenchymal transition, therapeutic angiogenesis His lab has pioneered human vascular smooth muscle cell line development and discovered novel genes in vascular remodeling. Scientific accolades include the Heart and Stroke Foundation's Barnett-Ivey Chair and Fellowships from the American Heart Association and American College of Cardiology. Recent Publications (2024): Mitochondrial calcium signaling in vascular disease 2023: Telomere length implications in atherosclerosis 2020: Ischemic vascular regeneration models Dr. Pickering's work has secured major operating grants from the Heart and Stroke Foundation and Canadian Institutes of Health Research. He leads the Robarts Research Institute's vascular biology program and maintains active collaborations in molecular cardiology and regenerative medicine.

Tuomas Tammelaمشاهده پروفایل

استادیار

• Cancer Biology
• Cellular Phenotypic Heterogeneity
• Cancer Stem Cells
• +۱۳ مورد دیگر

Tuomas Tammela is an Assistant Professor at the Weill Cornell Medicine Graduate School of Medical Sciences and an Assistant Member in the Cancer Biology & Genetics program at Memorial Sloan Kettering Cancer Center (MSKCC). His research focuses on understanding cellular phenotypic heterogeneity in solid tumors, particularly in lung adenocarcinoma, pancreatic cancer, and soft tissue sarcoma. His research interests include cancer cell plasticity, tumor evolution, cancer stem cells, and the impact of aging and exercise on cancer progression. He employs advanced methodologies such as single-cell genomics, proteomics, CRISPR-mediated gene activation, and genetically engineered mouse models to dissect the molecular mechanisms driving tumor heterogeneity and therapy resistance. The recent publications highlight a strong focus on identifying and characterizing highly plastic cancer cell states that contribute to therapeutic resistance. His work bridges molecular oncology with translational applications, aiming to develop strategies that force cancer cells into more therapy-sensitive states. Mark Foundation Emerging Leader Award (2021) American Cancer Society Research Scholar Award (2020) Rita Allen Scholar Award (2020) NCI R37 MERIT Award (2019) V Foundation Scholar Award (2019) AACR Next Generation Transformative Research Award (2018) Josie Robertson Young Investigator Award, MSKCC (2017) Dr. Tammela leads an active research lab that mentors trainees and collaborates across institutions. His lab receives significant funding from top-tier organizations, as evidenced by awards such as the NCI R37 MERIT Award and the V Foundation Scholar Award, supporting innovative projects on targeting intra-tumoral heterogeneity and cancer stem cell niches. The Tammela Lab develops and utilizes genetically engineered mouse models to study tumor initiation, progression, and response to therapy. The lab integrates molecular perturbation, lineage tracing, and single-cell analysis to understand cancer cell state dynamics and their interactions with the tumor microenvironment.

Wei Zhangمشاهده پروفایل

استادیار

• Vascular Biology
• Smooth Muscle Cell Biology
• Noncoding RNA
• +۳ مورد دیگر

Wei Zhang, PhD is an Assistant Professor in the Department of Cardiovascular Sciences at the Lewis Katz School of Medicine, Temple University. His research focuses on vascular wall disorders, smooth muscle cell (VSMC) phenotypic changes, and therapeutic target discovery. BSc in Pharmacy - Sun Yat-Sen University PhD in Biomedical Engineering - Sun Yat-Sen University Dr. Zhang’s work explores how VSMC heterogeneity contributes to pathologies like restenosis, aneurysm dissection, and atherosclerosis. He investigates mechanisms of VSMC proliferation, migration, and transdifferentiation using genetic, surgical, and dietary rodent models, including conditional knockout mice and lineage-tracing systems. His publications highlight advancements in single-cell transcriptomics, lncRNA (INKILN) targeting, and prime editing for tissue-specific gene function. Articles span Redox Biology , Circulation , Genome Biology , and Aging (Albany NY) , with trends in multiomics, gene editing, and aging-related vascular pathways. Scientific Awards: 2023 AHA Transformational Project Award 2023 AHA Second Century Early Faculty Independence Award 2023 Augusta University Intramural Grant 2023 ATVB Travel Grant for Early Career Investigators 2018 AHA Career Development Award Dr. Zhang’s lab utilizes humanized transgenic mice, lineage-tracing models, and cell cycle/senescence reporters to study vascular disease initiation and progression at high resolution.

James Hughesمشاهده پروفایل

مدرس

• Fatigue and fracture of metals
• Crack growth prediction
• Crack opening load measurement
• +۲ مورد دیگر

Dr James Hughes is a Lecturer at the Centre for STEM Education and Innovation , part of the Faculty of Sciences, Engineering and Technology at the University of Adelaide. His expertise lies in the fatigue and fracture of metals , with a focus on predicting crack growth and measuring crack opening loads . He remains an active researcher in these fields. As a co-supervisor, Dr Hughes supports postgraduate students at the Masters and PhD levels , emphasizing practical research in metallurgy and structural integrity. His contact details include james.m.hughes@adelaide.edu.au . While specific scientific awards are not mentioned in his current profile, his work contributes to structural engineering and materials science through both theoretical and experimental approaches.

Constance L. Cepkoمشاهده پروفایل

استاد

• Neuroscience
• Developmental Biology
• Genetics
• +۷ مورد دیگر

Constance L. Cepko serves as the Bullard Professor of Genetics and Neuroscience at Harvard Medical School, where she leads an active research laboratory focused on the mechanisms of central nervous system development and degeneration, with particular emphasis on the vertebrate retina. Her laboratory is housed in the New Research Building at 7 Avenue Louis Pasteur, Boston, MA. Dr. Cepko's research interests span multiple areas of developmental neuroscience and genetic approaches to neural circuit mapping. Her laboratory pioneered the use of transsynaptic viral tracers based on vesicular stomatitis virus (VSV), which can travel between synaptically connected cells in multiple organisms including mammals, birds, fish, and amphibians. These vectors can be engineered for anterograde or retrograde transmission and to cross specific numbers of synapses, enabling detailed neural circuit mapping. Her laboratory also developed innovative GFP-dependent biological activity systems (T-DDOG and Cre-DOG) that allow manipulation of gene expression and neural circuit activity specifically in GFP-expressing cells. Additionally, they have refined in vivo electroporation techniques for simultaneous delivery of multiple plasmids to study gene function and regulatory elements in retinal development. Research on retinal development focuses on the heterogeneity of retinal progenitor cells and mechanisms directing cell fate determination Studies of photoreceptor development examine rod versus cone specification and retinal patterning Gene therapy research investigates approaches to prevent photoreceptor death in retinal degeneration diseases Dr. Cepko's laboratory maintains active collaborations and has made significant contributions to understanding the gene regulatory networks controlling retinal cell fate decisions, particularly the Otx2-dependent network that determines rod versus bipolar cell fates. Her work has important implications for developing therapies for retinal degenerative diseases like retinitis pigmentosa.

• SNARE Proteins
• Membrane Transport
• Cell Biochemistry
• +۴ مورد دیگر

Prof. Dr. Gabriele Fischer von Mollard is a leading researcher at Bielefeld University's Faculty of Chemistry , holding the Biochemistry III professorship since 2005. She previously held positions at Ruhr University Bochum (2004) and University of Göttingen (1998-2004) where she led a junior research group funded by the Volkswagen Foundation. University studies in Biochemistry at Tübingen, Munich, and Berlin Diploma (1989) and PhD (1992) from Free University of Berlin Habilitation (2002) at University of Göttingen Her research focuses on membrane transport mechanisms , particularly the molecular roles of SNARE proteins in yeast and mammalian cells. Current projects include: Investigating NDRG3-GOSR2 interactions in ER-Golgi transport Characterizing SNARE protein deficiencies (vti1a/b) in neuronal development Engineering fungal L-amino acid oxidases for biocatalytic applications Recent publications highlight both fundamental discoveries in vesicular transport (15+ articles 2021-2025) and applied biocatalysis projects involving enzyme immobilization technologies. Her work bridges basic science with industrial applications through collaborations in enzyme engineering and protein production systems.