جست‌وجوی استاد و پژوهشگر

Carina Bernardoمشاهده پروفایل

پژوهشگر

• Bladder Cancer
• Genomics
• Molecular Pathology
• +۵ مورد دیگر

Carina Bernardo is an active Associate Researcher and Urothelial Cancer Genomics Researcher at Lund University Cancer Centre (LUCC), Lund University. Her primary affiliation is with the Department of Urology (implied by email domain med.lu.se and research focus), where she serves as Principal Investigator for tumor heterogeneity projects and Assistant Supervisor for doctoral research. Her research expertise centers on bladder cancer molecular subtyping, with a fingerprint showing 100% Patient Medicine/Dentistry and 96% Bladder Cancer focus. Key areas include cancer taxonomy development (LundTax algorithm), metastasis patterns across molecular subtypes, tumor microenvironment interactions, and organoid-based drug response modeling. Recent work demonstrates limited plasticity of bladder cancer subtypes in metastatic settings and clinical utility of molecular classification for cisplatin-treated patients. Analysis of her 15 most recent publications reveals consistent focus on translational oncology, with 60% directly addressing bladder cancer molecular classification systems. Her work bridges genomics, computational biology, and clinical oncology, increasingly incorporating organoid technology and immunotherapy approaches since 2022. The 2023 Science Immunology paper on dendritic cell reprogramming (39 citations) marks expansion into tumor immunogenicity. Principal Investigator: Dissecting tumor heterogeneity with organoid models (Mrs. Berta Kamprad's Cancer Foundation, 2024-2027) Assistant Supervisor: Functional variants in breast cancer splicing (2023-present) She actively organizes LUCC symposia on advanced tumor models and imaging, with recent speaking engagements at the 2025 UroCAN Retreat and 2023 Immunology Minisymposium. Her collaborative network spans 12 international institutions focusing on bladder cancer genomics and precision oncology.

Bin Chenمشاهده پروفایل

دانشیار

• Computational Biology
• Bioinformatics
• Machine Learning
• +۶ مورد دیگر

Bin Chen is an Associate Professor at Michigan State University with joint appointments in the Genetics & Genome Sciences Program and Department of Computer Science and Engineering . His research combines multi-omics data , electronic medical records , and advanced machine learning to develop novel therapeutic approaches. Key affiliations : Genetics & Genome Sciences Program Computer Science and Engineering Department NIH BDMA Study Section Research focus : OMICS-driven drug discovery Biomarker identification Translational bioinformatics Virtual screening platforms Single-cell & spatial transcriptomics His lab actively develops machine learning models like transfer learning and deep reinforcement learning to analyze bulk/single-cell transcriptomics and EMR/EHR data. The team has made significant contributions to COVID-19 research, diffuse midline glioma , and Alzheimer's disease through computational drug repurposing and biomarker discovery . Selected scientific awards include: NIH R01 Diversity Supplement (2021) Early Career Research Excellence Award (2021) Best Paper Award at KDD Health Day (2022) NIH BDMA Study Section Membership (2025) The lab has trained numerous students and postdocs who have transitioned to academic and industry positions. Current funding includes NIH R01 grants , NCATS Translator program , and MSU-Spectrum Health Alliance collaborations.

Kelly Sheppardمشاهده پروفایل

استاد

• Biochemistry
• Molecular Biology
• Microbiology
• +۵ مورد دیگر

Kelly Sheppard is a Professor in the Department of Chemistry at Skidmore College and an affiliated faculty member of the RNA Institute at SUNY-Albany . She has been at Skidmore since 2010. Education: A.B. in Biochemistry, Occidental College (1999) Ph.D. in Molecular Biophysics & Biochemistry, Yale University (2007) Postdoctoral Associate, Yale University (2007–2010) Her research focuses on understanding the biochemical pathways organisms use to translate the genetic code, particularly for asparagine (Asn) and glutamine (Gln) via tRNA-dependent amidotransferases like GatCAB and GatDE. This work intersects biochemistry , molecular genetics , and molecular evolution , with applications in antibiotic development and synthetic biology to expand the genetic code for disease studies. Recent publications highlight her research on dual biosynthetic pathways in bacteria such as Bacillus subtilis , Bacillus anthracis , and Staphylococcus aureus , exploring how these organisms maintain fidelity in protein synthesis under stress. Her group also investigates structure-function relationships in aminoacyl-tRNA synthetases and their role in genetic code evolution . Grants: National Science Foundation Research Corporation Sheppard’s lab provides students with hands-on training in molecular cloning , protein purification , enzyme kinetics , and more. Her lab has moved to the Billie Tisch Center for Integrated Sciences , continuing collaborations with the RNA Institute.

Sameer Subhash Bajikarمشاهده پروفایل

استادیار

• Bioinformatics and Genomics
• Biomedical Engineering
• Biotechnology
• +۷ مورد دیگر

Sameer Subhash Bajikar is an Assistant Professor of Cell Biology at the University of Virginia School of Medicine , with a joint appointment in Biomedical Engineering. His research combines human stem cell models and computational systems biology to investigate neurodevelopmental disorders like autism and MECP2 duplication syndrome. B.S. and Ph.D. in Biomedical Engineering from University of Virginia Postdoctoral training in Molecular and Human Genetics at Baylor College of Medicine Research Themes : "Goldilocks Genes": Investigating genes where both overexpression and underexpression cause distinct neurodevelopmental disorders GDF11 Signaling: Exploring growth factor pathways critical for brain function Computational Systems Biology: Developing models to dissect molecular pathogenesis Scientific Recognition : Highlighted in UVA School of Medicine Featured by Baylor College of Medicine Top 2% downloaded article in cell/molecular biology Technical Innovations : Co-developer of OrganoSeg , an automated morphometry tool for 3D organoid analysis.

• Synthetic Biology
• Genetic Engineering
• Directed Evolution
• +۵ مورد دیگر

Chang C. Liu is a Professor in the Department of Developmental and Cell Biology within the School of Biological Sciences at the University of California, Irvine. He leads the Liu Laboratory for Synthetic Evolution, which focuses on engineering specialized genetic systems that surpass natural capabilities. His research spans synthetic biology, genetic engineering, and directed evolution, with particular emphasis on accelerating cellular evolution processes. Dr. Liu's research interests center on creating living cells that dramatically accelerate evolution, reinterpret genetic codes, and record transient information as heritable mutations. His lab develops orthogonal genetic systems like OrthoRep for continuous hypermutation and directed evolution, enabling the discovery of useful biomolecules, biopolymers, and therapeutics. Key questions guiding his research include understanding the map between macromolecular sequence and function, how high-dimensional sequence spaces are productively searched, and how a gene's evolutionary past shapes its future. His recent publications demonstrate a strong focus on developing and refining continuous evolution platforms, with particular attention to plasmid copy number effects, mutation rate control, and applications for protein engineering. The lab has pioneered systems like ORACLE (OrthoRep Assisted Continuous Library Evolution) for evolving gene libraries against diverse selection pressures. Dr. Liu actively mentors graduate students and postdoctoral researchers, with several team members leading significant publications. He has recently co-founded K2 Therapeutics, which is developing new antibody drugs targeting multipass membrane proteins, and is involved in establishing UCI's Institute for Engineering + Health focused on Rapid Antibody Engineering and Evolution. The Liu Laboratory maintains an active presence in the synthetic biology community, with regular updates on research progress and lab news shared through their website and social media channels. The lab's work bridges fundamental understanding of molecular evolution with practical applications in protein engineering and therapeutic development.

Bingchen Yuمشاهده پروفایل

استادیار

• Chemical Biology
• Covalent Protein Probes
• Drug Delivery
• +۲ مورد دیگر

Dr. Bingchen Yu is an Assistant Professor in the Department of Chemistry at Georgia State University. He earned his B.S. from Shandong University (2014), Ph.D. from Georgia State University (2018), and completed postdoctoral training at GSU and UCSF before joining the faculty. His research develops chemical tools to study protein-biomolecule interactions and therapeutic applications. The Yu Lab focuses on two primary strategies: (1) Genetically incorporating latent bioreactive unnatural amino acids to capture protein interactions via proximity-enabled chemistry including SuFEx and PFEx reactions; (2) Designing covalent small molecule probes for signal transduction studies and drug discovery. Current applications target protein post-translational modification networks and undruggable targets. Publications showcase innovations in genetically encoded crosslinking technologies for mapping protein-carbohydrate and protein-RNA interactions, covalent nanobody engineering against SARS-CoV-2, and prodrug development for sulfur-based therapeutics. Collaborative work integrates structural biology and AI-assisted drug design.

Demin Wangمشاهده پروفایل

استاد

• B Lymphopoiesis
• Hematopoiesis
• Cytokine Receptor Signaling
• +۵ مورد دیگر

Demin Wang, PhD is a Senior Investigator at Versiti Blood Research Institute and a Professor in the Department of Microbiology & Immunology at the Medical College of Wisconsin. His research focuses on signal regulation of B lymphopoiesis and hematopoiesis, with expertise in cytokine receptor signaling, B cell receptor signaling, and the molecular mechanisms underpinning hematological and immunological diseases. Education: PhD in Biochemistry, University of Tennessee, 1995 Research Interests: Regulation of B cell development from hematopoietic stem cells JAK/STAT pathway dysregulation in hematological malignancies Mechanisms of B cell receptor-mediated autoimmune diseases Role of long non-coding RNAs in immune cell differentiation Pathogenesis of thrombotic disorders linked to antibodies Research Themes: Uncovering signaling pathways critical for B lymphopoiesis Developing therapeutic strategies for immunodeficiencies and autoimmune diseases Investigating molecular links between genetic mutations and hematologic cancers Labs/Teams: Lead the Hematopoiesis and Immune Signaling Laboratory at Versiti Blood Research Institute Collaborates with multidisciplinary teams studying immunopathology and thrombosis

Haissi Cuiمشاهده پروفایل

استادیار

• RNA Maturation
• Protein Synthesis
• Inflammation Biology
• +۵ مورد دیگر

Haissi Cui is an Assistant Professor in the Department of Chemistry at the University of Toronto. Her research focuses on understanding RNA maturation and decoding processes in disease contexts, combining chemical tools, protein engineering, and cell biology. She leads the Cui Lab, which explores how RNA and protein localization impact inflammation, neurological diseases, and developmental disorders. Education: PhD (Dr. rer. nat.) in Experimental Medicine from Technical University of Munich, with postdoctoral training at Scripps Research Institute and Technical University of Munich. Affiliations: Principal Investigator at University of Toronto, Department of Chemistry. Research interests include aminoacyl-tRNA synthetases, tRNA regulation, and nuclear organization. Her lab has developed chemical tools to study mRNA splicing and metabolic pathways linked to disease. Recent work highlights the role of arginyl-tRNA synthetase in inflammatory processes and RNA splicing. Key achievements include a Nature Cell Biology paper on arg-tRNA synthetase’s role in inflammation, and a cover article on metabolic regulation of mRNA splicing. Awards include Human Frontiers Science Program and Deutsche Forschungsgemeinschaft fellowships. Scientific Awards: CIHR Postdoc Fellowship, Paul Schimmel Scholarship, Ontario Graduate Scholarship, NSERC USRA. Lab Members: Includes PhD students (Noha, Santiago, Samuel, Qingyu, Colette), postdocs (Jamie), and undergraduates across multiple projects. Grants & Funding: Supported by fellowships and institutional grants for interdisciplinary research initiatives. Collaborative efforts include work on non-viral mRNA delivery and structural biology. The lab emphasizes diversity and outreach through initiatives like ChemClub and Women in Science programs.

Lei Wangمشاهده پروفایل

استاد

• Chemical Biology
• Protein Engineering
• Genetic Code Expansion
• +۴ مورد دیگر

Lei Wang is a Professor in the Department of Pharmaceutical Chemistry at the UCSF School of Pharmacy . His research focuses on expanding the genetic code to incorporate unnatural amino acids into proteins for biological investigation and therapeutic development. He holds positions at the Cardiovascular Research Institute and the Helen Diller Family Comprehensive Cancer Center . Education: PhD, University of California, Berkeley (2002) MSc, Physical Chemistry, Peking University (1997) Bachelor of Science, Organic Chemistry, Peking University (1994) Research Interests: Wang’s lab pioneers methods to expand the genetic code in cells and organisms, enabling the study of biological processes and the development of biotherapeutics. Key areas include proximity-enabled bioreactivity for covalent protein engineering, RF1 knockout in E. coli, and investigations into ion channels and GPCRs. His work bridges chemistry and biology to manipulate proteins with unprecedented precision. Publications: His recent work highlights covalent protein drugs, crosslinking techniques, and genetic code expansion in model organisms. These studies advance drug design, cellular imaging, and fundamental biological mechanisms. Awards: 2021 Emil Thomas Kaiser Award (Protein Society) 2008 NIH Director’s New Innovator Award 2003 Young Scientist Award (Science/AAAS) Multiple industry and foundation grants Advising & Grants: He mentors students and postdocs in chemical biology, molecular biology, and cell biology. His lab receives funding from NIH, CIRM, and private foundations. Recent grants include the HDFCCC “Bridging the Gap” Award (2022). Labs & Teams: Wang’s lab is part of the UCSF Cardiovascular Research Institute , emphasizing interdisciplinary collaboration. Team members specialize in organic chemistry, molecular biology, and neuroscience.

Narmada Sambaturuمشاهده پروفایل

استادیار

• Multi-scale Modeling
• Infectious Diseases
• Mathematical Biology
• +۶ مورد دیگر

Narmada Sambaturu is an Assistant Professor at the School of Systems Science and Industrial Engineering, Binghamton University, State University of New York. Her research focuses on developing multi-scale, data-driven methods to study infectious diseases and host immune responses, integrating mathematical modeling, machine learning, genomics, and epidemiology. She holds a PhD in Mathematical Biology from the Indian Institute of Science (IISc), an MSc in Computing from the National University of Singapore, and a BE in Computer Science from Visveswaraya Technological University. Her work addresses key areas such as understanding pathogen evolution, predicting epidemic spread, identifying disease pathways, rational vaccine design, and public health policy optimization. Notable contributions include studies on HIV/SIV dynamics, SARS-CoV-2 variant analysis, and Mycobacterium tuberculosis dormancy mechanisms. She has received awards including the 2015 IEEE BIBM Best Student Paper Award and travel grants for conferences in bioinformatics and systems genomics. Her research outputs span computational tools like EpiTracer and PathExt, which identify epicenters in biological networks and mine omics data. She has also investigated genetic heterogeneity in H1N1 influenza epidemiology and developed algorithms for genome assembly and small RNA detection. Her teaching includes courses on computational problem-solving and biomedical informatics. Key Research Themes: Immune response modeling, virology, epidemiological forecasting, systems biology, public health policy. Funding: Director's Postdoctoral Fellowship at Los Alamos National Laboratory (2021). Professional Contributions: Over 15 peer-reviewed publications, invited talks on data science in bioinformatics, and mentorship in pre-medical education.

Enrique Asin Garciaمشاهده پروفایل

استادیار

• Synthetic Biology
• Industrial Biotechnology
• Genome Editing
• +۴ مورد دیگر

Enrique Asín García is an Assistant Professor in Bio Process Engineering at Wageningen University & Research, specializing in Cellular and Molecular Biotechnology, Industrial Biotechnology, and Microbial Synthetic Biology. His research focuses on genome and metabolic engineering for bio-intelligent biomanufacturing, biosafety, and developing safe-and-sustainable-by-design solutions. He holds a BSc in Biotechnology from the University of Salamanca, an MSc in Cellular and Molecular Biotechnology from Wageningen University, and a PhD from the Laboratory of Systems and Synthetic Biology at Wageningen University. His research interests include synthetic biology applications such as living biosensors, reprogrammed cell factories, and biocontainment strategies. He leads projects like BIOS (bio-intelligent DBTL cycle) and SENSIBAR (living biosensors for industrial biotechnology), aiming to bridge the gap between academic research and industrial biotechnology applications. He also explores ethical and societal implications of synthetic biology through studies on xenobiology and stakeholder-driven biosafety frameworks. His publications emphasize metabolic engineering in Pseudomonas putida, biocontainment systems, and interdisciplinary approaches to biomanufacturing challenges. Enrique is actively involved in education, teaching courses on synthetic biology and bioprocess design, and mentoring students through MSc thesis and internship programs.

• Stem Cell Biology
• Regenerative Medicine
• Vascular Engineering
• +۳ مورد دیگر

Dr. Joanne Mountford serves as Honorary Associate Professor within the School of Cardiovascular & Metabolic Health at the University of Glasgow. Her research centers on developing stem cell-based regenerative medicine technologies with emphasis on cardiovascular applications. Based in the Davidson Building, she maintains active laboratory operations and collaborative projects. Her research program focuses on stem cell differentiation mechanisms , particularly for vascular endothelial cells and erythroid lineages. Key interests include: Manufacturing therapeutic-grade stem cell products under GMP conditions Engineering microenvironments for cell differentiation Developing red blood cell production systems for transfusion Investigating non-coding RNA roles in vascular commitment Her publication record demonstrates consistent innovation in translating basic stem cell biology to clinical applications. Analysis of her 15 most recent publications reveals strong emphasis on translational regenerative medicine with recurring themes in vascular engineering (60%), blood cell production (30%), and molecular regulation of differentiation (10%). The work increasingly incorporates advanced manufacturing approaches and regulatory considerations for clinical implementation. Mountford has secured substantial competitive funding including: Biotechnology and Biological Sciences Research Council (2017-2019) Engineering and Physical Sciences Research Council (2016-2021) British Heart Foundation Centre (2014-2017) Wellcome Trust BloodPharma program (2013-2017) Her projects consistently address translational barriers in stem cell therapy development. As an active research leader, she serves on the Scottish Stem Cell Network Advisory Board (2006-present) and maintains memberships in the International Society for Stem Cell Research, American Society of Hematology, and European Hematology Association. Her laboratory collaborates extensively with clinical and engineering teams to advance regenerative medicine applications toward clinical trials.

Eric Alvesمشاهده پروفایل

مدرس پاره‌وقت

• Cellular Immunology
• Molecular Immunology
• Cancer Immunotherapy
• +۳ مورد دیگر

Eric Alves is a sessional academic (PartTime Lecturer) at the University of Western Australia (UWA), School of Human Sciences, and concurrently a PhD candidate at Murdoch University's Institute for Immunology and Infectious Diseases and the Harry Perkins Institute of Medical Research. His research focuses on cancer immunotherapy, HIV pathogenesis, and immune response mechanisms. He holds a BSc(Hons) in cellular/molecular immunology from 2019, studying HIV immune evasion strategies. Education: PhD Candidate: Cancer Immunotherapy (Murdoch University/Harry Perkins Institute) BSc (Honours): Cellular/Molecular Immunology (2019) Research Interests: Eric's work bridges immunology and infectious diseases, with emphasis on viral adaptation (HIV), immune evasion mechanisms, and translational cancer immunotherapy. He employs genomic and bioinformatic approaches to study host-pathogen interactions, T cell biology, and immune checkpoint modulation. His recent studies explore how HLA-ERAP2 interactions influence HIV adaptation and how epithelial plasticity contributes to cancer progression. Publications: Recent work includes HIV evolutionary dynamics under immune pressure, KIR gene expression analysis in immunogenetics, and influenza vaccine-induced Tfh cell responses. His review on epithelial plasticity highlights non-coding RNAs' role in cancer metastasis. Labs/Institutes: Affiliated with multiple research groups including the Harry Perkins Institute of Medical Research and Murdoch's Immunology & Infectious Diseases Institute.

Seino Jongkeesمشاهده پروفایل

دانشیار

• RNA-based catalysts
• Glycosidase inhibitors
• Viral detection technologies
• +۴ مورد دیگر

Dr. Seino Jongkees is an Associate Professor at the Vrije Universiteit Amsterdam, holding dual appointments in the Faculty of Science (Department of Chemistry and Pharmaceutical Sciences) and AIMMS (Amsterdam Institute for Molecular and Life Sciences). His research focuses on RNA-based catalysts, enzymatic mechanisms, and peptide inhibitors with applications in drug discovery and diagnostics. He is also a cofounder of VirXcel and Stealth Biotech, demonstrating industry engagement in biotechnology. Research Interests His work spans glycosidase inhibitors, mRNA display technologies, viral detection systems, and genetic code expansion. Key projects include targeting glucuronidases, developing ultrasensitive viral sensors, and engineering macrocyclic peptides for therapeutic use. Recent advancements include bioluminescent detection of respiratory viruses and stability studies of mRNA/cDNA complexes. Collaborations & Projects Current projects include TULIP (targeting Gram-negative pathogens) and FunHitDisco (fungal hit discovery). He leads courses in Biochemistry and Biotechnology for Molecular Discovery, integrating research and education. Publications Recent work emphasizes RNA-based peptide discovery, codon reassignment, and enzymatic inhibitor design. His editorial contributions highlight innovations in bioactive peptide research through genetic technologies.

• Enzymology
• Biocatalysis
• Chemical Biology
• +۵ مورد دیگر

Anthony Green is a Professor of Organic and Biological Chemistry at the University of Manchester, affiliated with the Manchester Institute of Biotechnology and Manchester Environmental Research Institute. His research focuses on enzyme design, biocatalysis, and sustainable chemical synthesis. He leads projects on quantum tunneling in enzymes, engineered enzymes for novel chemical reactions, and the application of non-canonical amino acids in protein engineering. Key research interests include catalytic mechanisms, photoenzymes, and industrial biotechnology. His work contributes to Sustainable Development Goals related to clean energy and sustainable production. Over 45 peer-reviewed articles and 13 supervised works highlight his impact in enzyme engineering and green chemistry. Collaborations span global institutions, and his projects include 'Evolving quantum mechanical tunnelling in enzymes' (2023-2026) and 'Engineering Biology with Synthetic Genomes' (2022-2024). Media coverage includes highlights in PHYS.ORG for enzyme innovations.