جستجوی استاد راهنمای دانشگاهی

Jianhua Xing is an Associate Professor in the Department of Physics & Astronomy at the University of Pittsburgh , affiliated with the Dietrich School of Arts and Sciences . His research focuses on applying physics-based approaches to study biological systems, particularly cell phenotypic transitions (CPTs) and their underlying dynamics. He integrates quantitative single-cell measurements with computational and theoretical analyses to understand how cells transition between stable states. Key research areas include: Nonequilibrium systems and rate theories for biological transitions Single-cell trajectory analysis and live-cell imaging Epithelial-mesenchymal transition (EMT) dynamics Gene regulatory networks and stochastic processes Biological applications of dynamical systems theory Recent work highlights the coupling between EMT and cell cycle arrest, leveraging machine learning frameworks (e.g., LivecellX ) for high-resolution imaging analysis. His lab also explores chromosomal dynamics and mechanotransduction in stem cell aging. Publications emphasize data-driven modeling and theoretical insights, with contributions to frameworks like GraphVelo and Graph-Dynamo for inferring cellular state transitions. Collaborative efforts bridge physics, biology, and computational science to address fundamental biological questions. No awards or grants are explicitly listed in the provided texts. His research group focuses on advancing systems biology through interdisciplinary methods, with a lab dedicated to quantitative analysis of cellular processes.

• Biophysics
• Systems Biology
• Cell Biology
• +۷ مورد دیگر

Océane Martin is a Lecturer in Clinical Microbiology at the University of Bordeaux, where she conducts her research at the Institute of Cellular Biochemistry and Genetics, a joint unit of CNRS and the university. Her work bridges clinical microbiology, oncology, and nutritional sciences. Research Interests: Océane Martin specializes in the role of the microbiota in cancer development, particularly focusing on: Links between processed meat consumption, nitrites/nitrates, and colorectal cancer. The role of pathogenic bacteria like Helicobacter pylori and Salmonella in gastric and colorectal cancers. The gut-brain axis in glioblastoma, including how the microbiota influences tumor progression and therapeutic resistance through the GLIOBIOTA project. Intratumoral microbiota in brain tumors and their functional implications. Publication Trends: Her recent publications reflect a strong focus on bacterial genotoxins, DNA damage responses, host immune modulation, and dietary factors in carcinogenesis. Her work integrates molecular microbiology with immunology and cancer biology, often using in vivo models to study host-pathogen dynamics. Scientific Contributions: Member of ANSES working group (2020–2022) on nitrite salts in food. Invited expert at the French National Assembly on nitrite-related health risks. Regular contributor to public science communication via The Conversation and national media. Advising and Grants: While no formal students are listed, her leadership in the GLIOBIOTA project suggests active mentorship and grant-funded research. Her involvement in national expert panels and interdisciplinary projects indicates sustained funding and collaborative research networks. Labs and Teams: She conducts research at the Institute of Cellular Biochemistry and Genetics (University of Bordeaux / CNRS), contributing to teams focused on infection biology, microbiota, and cancer. Her work aligns with translational research initiatives linking diet, microbiology, and oncology.

• Microbiota
• Cancer Biology
• Clinical Microbiology
• +۹ مورد دیگر

Professor Ben Steventon is a faculty member at the University of Cambridge in the Department of Genetics . His research focuses on developmental biology, particularly the regulation of cell fate decisions during embryonic axis patterning in zebrafish and chick embryos. Key research themes include: Downward causation in multi-tissue interactions Pattern emergence through dynamic gene regulatory networks Multi-scale regulation of developmental timing His lab employs live quantitative imaging and single-cell transcriptomics to address these questions. Notable affiliations include: Theme Leader (Reproduction, Development and Lifelong Health) Open Research Representative (Cambridge DORA committee) Chair of Microscopy Steering Committee He has received the Wellcome Trust/Royal Society Sir Henry Dale Fellowship and actively mentors researchers such as: Postdoctoral Research Associates: Dr Qiyu Chen, Dr Imen Lassadi, Dr Guillermo Serrano-Najera, Alice Yuen Research Assistants: Oskar Batty, Apolline Delahaye Postgraduate Students: Alexandra Neaverson, Yuri Takahashi

• Developmental Biology
• Evolutionary Developmental Biology
• Gene Regulatory Networks
• +۳ مورد دیگر

Steven M. Dubinett is a distinguished academic leader at the University of California Los Angeles (UCLA), serving as Dean of the School of Medicine and holding professorships in Medicine, Pathology and Laboratory Medicine, and Molecular and Medical Pharmacology. His work is deeply integrated with key research centers including the UCLA Jonsson Comprehensive Cancer Center and the UCLA Clinical and Translational Science Institute, where he drives innovation in lung cancer research and translational medicine. Dubinett earned his medical degree from Rutgers New Jersey Medical School in 1980, followed by an internship and residency in Internal Medicine at University Hospital and UCLA. He completed specialized fellowships in Pulmonary Medicine at Massachusetts General Hospital and in Tumor Immunology at Harvard Medical School, establishing the foundation for his career at the intersection of pulmonary medicine and cancer research. Dr. Dubinett's research program is centered on the pathogenesis of lung cancer, with particular emphasis on translational approaches to understanding immunobiology, tumor microenvironment dynamics, and mechanisms of epithelial-mesenchymal transition in human non-small cell lung cancer. His laboratory has made seminal contributions to understanding how chronic inflammation drives lung carcinogenesis and how these insights can be translated into novel therapeutic strategies. His work bridges molecular mechanisms with clinical applications, focusing on identifying targets for lung cancer interception and prevention. Analysis of Dr. Dubinett's recent publications (2023-2025) reveals a sophisticated integration of multi-omics approaches with spatial analysis to understand lung adenocarcinoma evolution. His research increasingly focuses on tumor heterogeneity, immune microenvironment characterization, and innovative immunotherapeutic approaches including dendritic cell vaccines and engineered immune cells. A significant portion of his work addresses mechanisms of immunotherapy resistance and strategies to overcome it through combination approaches. Among his numerous accolades, Dr. Dubinett received the prestigious William S. Middleton Award from the U.S. Department of Veterans Affairs in 2019, the American Thoracic Society Recognition Award for Scientific Accomplishments in 2008, and the Stanley Blatt Award for Lung Cancer Research in 1999. His work has been consistently recognized by the American Lung Association through multiple awards spanning his career. Dr. Dubinett has secured substantial research funding throughout his career, including NIH grants and institutional support that has enabled his team to pursue cutting-edge approaches to lung cancer diagnosis and treatment. His leadership extends to national advisory roles, including chairing the FDA Cellular, Tissue and Gene Therapies Advisory Committee, and representing UCLA in international research collaborations with the Chinese Academy of Sciences. He has mentored numerous physician-scientists who have gone on to establish their own research programs in oncology and pulmonary medicine. Dr. Dubinett leads a multidisciplinary research team within the UCLA Jonsson Comprehensive Cancer Center focused on translating basic discoveries into clinical applications. His laboratory employs advanced techniques in molecular biology, immunology, and systems biology to investigate the molecular mechanisms of lung cancer development and progression. Current research directions include developing non-invasive diagnostic approaches using liquid biopsies, understanding the evolution of premalignant lesions, and developing novel immunotherapeutic strategies to enhance T-cell responses against lung cancer.

• Lung Cancer Research
• Translational Medicine
• Immunobiology
• +۵ مورد دیگر

Christopher J. Lengner is the Harriet Ellison Woodward Professor and Chair of the Department of Biomedical Sciences at the University of Pennsylvania School of Veterinary Medicine. He is a member of the Institute for Regenerative Medicine, NIH P30 Center for Molecular Studies in Digestive and Liver Diseases, and Abramson Cancer Center, with roles in training and research leadership. Education : PhD in Cell and Molecular Biology from the University of Massachusetts Medical School (2004). His research focuses on molecular mechanisms governing stem cell potency and their dysregulation in diseases like cancer and regenerative failure. Using genetic, genomic, and single-cell approaches in murine and human systems, his lab has uncovered novel pathways in intestinal stem cell hierarchy, cancer ontogeny, and therapeutic targeting. Recent publications highlight work in colorectal cancer metastasis (PI3K/AKT, NOTUM inhibition), intestinal regeneration (mTORC1, FLASH radiotherapy), and tumor microenvironment dynamics. Collaborations span human induced pluripotent cells and patient samples. Scientific Awards : Ruth L. Kirschstein Postdoctoral Fellowship He mentors graduate students (Ryan Cedeno, Maryam Yousefi) and leads the Center for Animal Transgenesis. His lab’s integrative studies bridge basic science to translational applications in oncology and regenerative medicine.

• Stem Cell Biology
• Cancer Biology
• Molecular Genetics
• +۳ مورد دیگر

Ramana V Davuluri serves as Professor in the Department of Biomedical Informatics at Stony Brook University's Renaissance School of Medicine. With over 20 years of experience in bioinformatics and computational genomics, he leads research at the intersection of machine learning and cancer genomics, focusing on translating high-dimensional -omic data into clinically actionable insights through statistically rigorous methodologies. Dr. Davuluri's research spans Machine Learning applications in Cancer Data Science , isoform-level gene regulation , and precision-medicine development. His lab pioneers bioinformatics solutions for genomic data interpretation, with emphasis on developing machine learning algorithms that convert NextGen sequencing outputs into experimentally testable discovery models. A core focus involves creating rapid biomarker identification systems from human tissue and blood samples through integrated computational-experimental approaches in systems biology. Analysis of his 2023-2025 publications reveals a dominant trend toward genomic foundation models (e.g., DNABERT variants), multi-omic cancer subtyping , and time-dependent therapeutic strategies for pediatric brain tumors and ovarian cancer. His work consistently bridges computational innovation with biological validation across diverse cancer types including glioma, lung adenocarcinoma, and high-grade serous carcinoma. As Principal Investigator for multiple multi-investigator and multi-site projects, Dr. Davuluri directs research integrating high-throughput experimental procedures with advanced data-mining techniques. His laboratory maintains strong collaborations across oncology, neuroscience, and immunology domains while developing genomics-based decision support systems for clinical translation. The Davuluri Lab employs a systems biology framework to develop novel informatics tools for precision oncology, with particular emphasis on translating genomic discoveries into clinical applications through biomarker discovery and therapeutic strategy optimization.

• Machine Learning
• Cancer Data Science
• Gene Regulation
• +۴ مورد دیگر

Prof. Sara Merino Aceituno is a Professor at the Faculty of Mathematics, University of Vienna, leading research in kinetic theory and its applications to biology, medicine, and social sciences. She holds roles as Vice-Dean of the Faculty and Head of the Institute of Mathematics. Her work bridges mathematical models with experimental data, focusing on emergent phenomena in collective dynamics, opinion formation, and cell behavior. She teaches advanced courses on kinetic theory, biomathematics, and mathematical strategies for learning. Her contributions include modeling cell delamination, nematic alignment, and swarm dynamics through PDEs and probabilistic methods. Collaborations with experimentalists drive her interdisciplinary research. She actively engages in education, advising, and public outreach, including a video series explaining mathematical patterns in nature. Her research emphasizes understanding macroscopic patterns arising from microscopic interactions in complex systems. Education: Holds a PhD in Mathematics, with expertise in kinetic theory and applied partial differential equations. Teaching and leadership roles reflect her commitment to academic excellence and student support. Her work integrates experimental and computational models to study clonal dynamics in tissues and mechanical constraints in epithelial layers. She has authored over 20 papers on topics ranging from active matter to opinion formation networks, contributing to both theoretical advancements and practical applications in biology and social sciences. Research focuses on deriving hydrodynamic and continuum models from particle systems, analyzing stability and bifurcations in collective behavior. Grants and collaborations include the Vienna Biocenter PhD Program and experimental groups in cell biology. Her lab explores how environmental factors influence particle swarms and how mechanical forces shape cell cycles in pseudostratified epithelia.

• Kinetic Theory
• Partial Differential Equations
• Mathematical Biology
• +۵ مورد دیگر

Judith West-Mays is a Professor in the Department of Pathology & Molecular Medicine at McMaster University . Her research focuses on: Molecular mechanisms of eye development and disease Role of transcription factors (AP-2β, AP-2α) in ocular morphogenesis Transforming Growth Factor Beta (TGF-β) signaling in epithelial-mesenchymal transition (EMT) Matrix Metalloproteinases (MMPs) in vision disorders Biomaterials for intraocular pressure management Key scientific contributions include: Elucidating AP-2β's role in trabecular meshwork formation and glaucoma Characterizing MMP-9's impact on aqueous humor drainage Developing conditional knockout mouse models for vision research Investigating YAP signaling in lens fibrosis Creating mucoadhesive micelles for glaucoma therapy Scientific awards : Brockhouse Canada Prize (2025) for interdisciplinary vision health research Teaching : Biomedical Engineering II (2018) at McMaster University. Collaborators include Taiyab, Sheardown, and Ball. Research hubs involve McMaster's interdisciplinary vision science team.

• Aging
• Animal Cell and Molecular Biology
• Genetically Modified Animals
• +۵ مورد دیگر

Kiven Erique Lukong is a Professor in the Department of Biochemistry, Microbiology & Immunology at the University of Saskatchewan's College of Medicine. His research focuses on breast tumor kinase (BRK) and related kinases, particularly their roles in breast cancer progression and metastasis. He holds a Ph.D. in Biochemistry from the University of Montreal and has collaborated with institutions globally, including the University of Ngaoundere in Cameroon. His work is supported by grants from NSERC and the University of Saskatchewan. Education: B.Sc. Biochemistry, Keele University, UK (1988) B.A. French, Keele University, UK (1988) M.A. Linguistics, University of Montreal (1992) M.Sc. Biochemistry, University of Montreal (1996) Ph.D. Biochemistry, University of Montreal (2002) Research Interests: Dr. Lukong's lab investigates BRK and related kinases (FRK, SRMS) in breast cancer. Key areas include: BRK's role in tumor formation and metastasis BRK as a diagnostic/prognostic marker Interactions with estrogen receptor signaling Phosphoproteomics and kinase substrate identification His work combines molecular biology, proteomics, and translational research to uncover therapeutic targets. Grants & Collaborations: NSERC Operating Grant (2017–2021) CoMBRIDGE Funding Grant (2019–2022) Memorandum of Understanding with University of Ngaoundere (2018) Labs & Teams: The Lukong Lab at the University of Saskatchewan is equipped for advanced proteomics, cell biology, and in vivo modeling. Collaborations include Dr. Anne-Claude Gingras' lab for Bio-ID/Mass Spectrometry training.

• Breast Cancer Research
• Molecular Oncology
• Cellular Signaling Pathways
• +۳ مورد دیگر

Steven D. Leach is Professor of Molecular and Systems Biology, Surgery, and Medicine at the Geisel School of Medicine at Dartmouth, where he also holds the Preston T. and Virginia R. Kelsey Distinguished Chair in Cancer and serves as Director of the Dartmouth Cancer Center (Norris Cotton Cancer Center). He has previously held leadership and faculty positions at Memorial Sloan Kettering and Johns Hopkins University. MD, Emory University BS in Biology, Princeton University (with high honors) Additional training at Yale and MD Anderson Dr. Leach's research is centered on pancreatic cancer biology, with a focus on understanding early tumorigenic events through developmental and molecular pathways. His lab utilizes mouse and zebrafish models to investigate epithelial plasticity, oncogenic signaling (particularly Notch and Kras), immune responses, and clonal evolution in pancreatic neoplasia. His work has revealed key mechanisms linking pancreatic development to cancer, including the role of acinar cells as cells of origin and the discovery of unique immune neoepitopes in long-term survivors. The selected publications, spanning from 2003 to 2017, reflect a sustained focus on the molecular and immunological underpinnings of pancreatic cancer. Themes include oncogenic signaling (Notch, Kras), tumor microenvironment interactions, epithelial-mesenchymal transition, and immune neoantigen landscapes. These works, published in top journals like Nature and Cell , demonstrate a trajectory from mechanistic discovery to translational immunology. Fellow of the American Association for the Advancement of Science (AAAS), 2019 Robert Woodruff Fellow, Emory University Dr. Leach has a strong record of mentorship, having trained 32 graduate students and postdoctoral fellows, many of whom have achieved independent faculty positions and NIH funding. He has been the principal investigator on numerous NIH grants, including R01, P01, P30, U01, S10, and T32 awards, supporting both research and training initiatives. His lab currently includes research scientists, graduate students, and postdoctoral associates engaged in projects on mRNA splicing, chromatin dynamics, and clonal evolution. The Leach Laboratory is an active research group within the Dartmouth Cancer Center, focusing on translational pancreatic cancer research. Lab members include graduate students from the Molecular and Cellular Biology program, postdoctoral researchers, and research scientists, working collaboratively on projects that bridge basic science and clinical applications. The lab utilizes advanced model systems and genomic technologies to uncover fundamental mechanisms of cancer initiation and progression.

• Pancreatic Cancer Biology
• Cancer Development and Tumorigenesis
• Molecular and Systems Biology
• +۸ مورد دیگر

Lill-Tove Rasmussen Busund is a Professor and Consultant Pathologist at the Department of Medical Biology, UiT The Arctic University of Norway. Her research focuses on translational cancer studies with emphasis on cancer biomarkers in tissue and blood, combining molecular biology with artificial intelligence applications in pathology. She leads the Translational Cancer Research Group (TCRG) and contributes to projects like the TNM-Immune Cell Score Trial and AI–Pathology initiatives. Role: Professor/Consultant Pathologist University: UiT The Arctic University of Norway Department: Department of Medical Biology Email: lill.tove.rasmussen.busund@uit.no Rasmussen Busund's work spans epidemiological cancer research , multi-omic data integration , and machine learning applications for cancer diagnostics. She develops prognostic and predictive biomarkers using population-based cohorts like the NOWAC study, with particular attention to hormone-dependent cancers and immune microenvironment analysis . Recent publications highlight her expertise in digital pathology and AI-driven tumor classification , including studies on microRNA expression patterns in breast and colon cancer, immune cell score development for NSCLC, and computational approaches to lymphocytic infiltration assessment. Her research directly impacts precision oncology and immunotherapy response prediction . She contributes to teaching as leader of the Musculoskeletal System course at the Medical School, and maintains active participation in scientific knowledge migration projects like the transition to the National Science Archive (NVA). Her ORCID identifier is 0000-0001-8235-6163 .

• Cancer Biomarkers
• Translational Cancer Research
• Digital Pathology
• +۳ مورد دیگر

Francisco J. Naya is Associate Professor of Biology at Boston University and member of the Whitaker Cardiovascular Institute. His research investigates gene regulation in cardiac and skeletal muscle development, focusing on noncoding RNA mechanisms in differentiation and disease. Naya's lab studies how noncoding RNAs, particularly from the imprinted Dlk1-Dio3 locus, coordinate mitochondrial function and chromatin dynamics during myogenesis. Research examines Meg3 RNA's role in muscle regeneration through epithelial-mesenchymal transitions and cellular plasticity. Publications establish connections between MEF2 transcription factors, metabolic regulation, and chromatin organization in muscle cell state determination. Work advances therapeutic understanding of muscular dystrophies and cardiac pathologies through regulatory network analysis.

• Cardiac Development
• Muscle Regeneration
• Noncoding RNAs
• +۳ مورد دیگر

Dr. Thea Tlsty is a Professor at the University of California San Francisco (UCSF) School of Medicine, Department of Pathology. With over 25 years of experience in cancer biology, she leads multidisciplinary research on epithelial-stromal interactions, chronic inflammation, and cellular plasticity in carcinogenesis. Her lab developed the first biomarkers for ductal carcinoma in situ risk stratification and discovered rare pluripotent cells in normal tissues with implications for metaplastic cancers. Education: BS in Zoology (University of South Florida, 1973) PhD in Molecular Biology (Washington University, 1980) Predoctoral Fellow (Washington University, 1976-1980) Postdoctoral Fellow & Senior Research Associate (Stanford University, 1981-1985) Dr. Tlsty's research focuses on: Stromal-epithelial stress response mechanisms Chronic inflammation's role in cancer CD36 repression in high mammographic density Pluripotent cell biology Multi-investigator grant projects Her 15 most recent publications highlight trends in proteomics, spatial transcriptomics, and multi-omics integration to study tumor microenvironment dynamics, particularly in breast, esophageal, and colorectal cancers. Scientific Awards: Cancer Research UK Grand Challenge Grant (£20M) NCI Outstanding Investigator Award Blaffer Distinguished Lectures (MD Anderson) Nakahara Award (Princess Takamatsu Foundation) KOMEN Scholar & AVON Scholar Elected AAAS Fellow NCI Knudson Award Dr. Tlsty has received continuous NIH funding since 1987, including ongoing R35 grant (R35CA197694) for studying stress-associated cellular plasticity. Her lab's translational insights bridge basic discoveries with clinical applications for cancer prevention and therapy.

• Epithelial-stromal interactions
• Genomic instability
• Chronic inflammation and cancer
• +۳ مورد دیگر

Susan W. Volk is the Corinne R. and Henry Bower Professor of Surgery at the University of Pennsylvania School of Veterinary Medicine , where she also serves as a Professor in Soft Tissue Surgery and a faculty member of the Bioengineering Graduate Group. A board-certified veterinary surgeon (Diplomate, American College of Veterinary Surgeons), her work bridges regenerative medicine , collagen biology , and cancer microenvironment research . Education BA in Biology, University of Pennsylvania (1991) VMD in Veterinary Medicine (1995) PhD in Cell and Molecular Biology (1998) Volk's research focuses on dynamic reciprocity between cells and extracellular matrices , particularly the role of Type III Collagen (Col3) in cutaneous wound healing, fibrosis, and tumor suppression. Her lab has pioneered understanding of Col3's ability to direct stromal organization, limit scar formation, and suppress cancer metastasis through matrix regulation. Key publication trends include Prevention of scar overproduction via Col3 modulation Stromal signatures predicting cancer outcomes in companion animals Development of collagen-based biomaterials for regenerative therapies Electrical stimulation and stem cell applications in wound repair Interferon-oxysterol defense against tumor vesicles Scientific Awards 2019 Emerging Inventor of the Year, Penn Center for Innovation 2021 Translational Regenerative Science Award, Wound Healing Foundation Editorial Board Member, Wound Repair and Regeneration Vice President (2023), Wound Healing Society Grants & Collaborations : Multiple NIH R01 grants, member of Wound Healing Society and North American Veterinary Regenerative Medicine Association boards. Her lab collaborates with Penn Vet Cancer Center and international institutions on cross-species fibrosis and oncology studies.

• Extracellular Matrix Biology
• Collagen Type III
• Wound Healing
• +۵ مورد دیگر

Tian Hong is an Associate Professor at the Department of Biological Sciences, The University of Texas at Dallas , with a joint appointment as Research Associate Professor at the Department of Biochemistry & Cellular and Molecular Biology, The University of Tennessee, Knoxville . His research focuses on systems biology, bioinformatics, cancer biology, and mathematical biology , particularly the plasticity and heterogeneity of epithelial and immune cells during development and cancer progression . He develops computational and mathematical models for gene regulatory networks, pattern formation, and dynamical systems. Education : PhD in Genetics, Bioinformatics and Computational Biology from Virginia Tech; MS in Bioinformatics from Nanyang Technological University, Singapore; BS in Biological Sciences from Nanyang Technological University, Singapore. Previous Appointments : Associate Professor (2023–2024) and Assistant Professor (2017–2023) at The University of Tennessee, Knoxville. His recent publications explore noncoding RNA-driven oscillations , Turing pattern formation without feedback , and epithelial-mesenchymal transitions using single-cell transcriptomics and mathematical modeling . He has received the Professional Promise in Research and Creative Achievement Award (2024) and the Transdisciplinary Team Science Fellow (2009). His work is funded by NIH grants including R35GM149531 (PI) and R01GM140462 (completed PI). Dr. Hong advises PhD and Master’s students and collaborates with researchers at the Center for Systems Biology, UT Dallas . His lab ( link ) actively seeks undergraduate, graduate, and postdoctoral researchers interested in interdisciplinary computational biology .

• Systems Biology
• Bioinformatics
• Cancer Biology
• +۷ مورد دیگر