جست‌وجوی استاد و پژوهشگر

Jennifer Rossمشاهده پروفایل

استاد

• Biophysics
• Soft Matter Physics
• Biological Condensed Matter Physics
• +۵ مورد دیگر

Jennifer Ross is a Professor of Physics and Associate Dean for Creativity, Scholarship, and Research at the College of Arts & Sciences of Syracuse University . As a biophysicist, she investigates how cells organize their interiors through self-assembly and active matter principles, focusing on the microtubule cytoskeleton and enzyme-driven systems using single-molecule imaging . Her research bridges fundamental physics with biological organization . Education: Ph.D. in Physics, University of California, Santa Barbara (2004) B.A. in Physics and Mathematics, Wellesley College (2000) Research Focus: Self-organization of cytoskeletal networks Active matter dynamics in biological systems Motor protein interactions and cargo transport Programming circadian materials via biomolecular systems Microtubule severing mechanisms Recent Article Trends: 2025 studies explore kinesin-driven cytoskeletal composites, urease-DNA origami engineering, and crosslinker-regulated network mechanics 2024-2023 work examines ionic strength effects on microtubules, programmable circadian materials, and motor-cargo dynamics Earlier studies analyze actin-microtubule composites, liquid crystal phase control, and severing enzyme mechanisms Scientific Awards: Fellow of the American Physical Society (APS) and American Association for the Advancement of Science (AAAS) Cottrell Scholar (2025) and STAR Award Margaret Oakley Dayhoff Award (Biophysical Society) Grants: Leads multiple NSF, Sloan Foundation, and Research Corporation grants for projects like "Energy and Entropy Sculpting" and "Explorations: SUPER-Tech SHIP" . Teaching: Offers courses in experimental physics, microscopy, and biophysics, including a globally adopted hands-on microscope-building curriculum. Lab: Heads the Bio-Active Matter Lab , studying how cells harness noisy systems for autonomous organization.

Omar A. Salehمشاهده پروفایل

استاد

• Biophysics
• Soft Matter Physics
• Polymer Physics
• +۵ مورد دیگر

Professor Omar A. Saleh is a distinguished physicist and materials scientist at the University of California, Santa Barbara, holding appointments in both the Materials and Physics Departments. Since summer 2023, he has served as Chair of the Materials Department and maintains a minority appointment in the Biomolecular Science and Engineering (BMSE) Program, where he previously served as Director from 2013-2017. His educational background includes a B.S. in Physics from MIT (1997) and a Ph.D. in Physics from Princeton (2003), supported by a Hertz Fellowship. Following postdoctoral work at École Normale Supérieure in Paris developing single-molecule techniques for motor protein/DNA studies, he joined UCSB in 2005. Saleh's research centers on fundamental principles of biomolecular behavior through experimental investigation of biopolymer elasticity and biomimetic organelles. His lab pioneers precision single-molecule stretching experiments to study entropic/energetic contributions in soft systems and creates life-like behaviors using reconstituted nucleic acid/protein assemblies. Key focus areas include DNA nanostar phase separation, liquid-liquid phase behavior, intrinsically disordered proteins, and non-equilibrium biomolecular systems. His publication trends reveal a strong emphasis on biomolecular condensates (2023-2025), with recurring themes in DNA nanotechnology, polyelectrolyte physics, and single-molecule mechanics. Recent work explores tension-mediated control of phase separation, transcriptional regulation of biomolecular liquids, and active matter principles in DNA systems. NSF CAREER Award (2008) Bessel Research Award from Alexander von Humboldt Society (2017) Fellow of the American Physical Society (2019) Saleh actively mentors graduate students and postdocs including Sam Wilken, Gabrielle Abraham, Anna Nguyen, and Aria Chaderjian, whose research spans DNA nanostar liquids, active droplets, and complex coacervation. His lab develops innovative instrumentation including high-speed magnetic tweezers and GPU-based tracking systems, supported by grants such as NSF/MCB-BSF: Direct force measurements of intrinsically disordered proteins. The Saleh Group operates at BioE 3006, focusing on creating quantitative models of biological function through physical reconstitution.

Daniel Finleyمشاهده پروفایل

استاد

• Ubiquitin-Proteasome Pathway
• Proteostasis
• Protein Degradation
• +۷ مورد دیگر

Daniel Finley is a Professor of Cell Biology at Harvard Medical School (HMS), leading the Finley Lab focused on the ubiquitin-proteasome pathway and related regulatory mechanisms. He holds academic appointments within the Department of Cell Biology and sits on the Scientific Advisory Boards of Proteostasis and X-Chem Pharmaceuticals. His research investigates proteasome function, ubiquitin-like proteins, and proteostasis roles in diseases like Alzheimer’s and ALS. Dr. Finley earned his undergraduate degree in biochemistry from Harvard University and a Ph.D. in molecular biology from MIT. After postdoctoral training at MIT, he joined HMS in 1988. His lab explores topics including erythroid proteome remodeling, mitochondrial dysfunction, and neurodegenerative disease mechanisms. Key research areas include: (1) Ubiquitin-proteasome pathway regulation, (2) Proteasome structure/function, (3) Nonproteolytic roles of ubiquitination, and (4) Pathophysiological roles of proteostasis defects in diseases. His work bridges basic cell biology with translational medicine, particularly in neurodegeneration and anemia. Finley has secured NIH funding for projects like 'Regulation of Proteasome Activity' (R35GM145246) and 'Erythrocyte maturation through global proteome remodeling' (R01HL153970). Collaborations with industry and academic partners extend his impact in drug discovery and proteasome-targeted therapies. His lab’s contributions include defining ubiquitin chain editing mechanisms, identifying USP14’s role in mitophagy, and elucidating proteostasis defects in Alzheimer's models. Research tools developed include advanced cryo-EM analyses of proteasomal structures and functional assays for ubiquitin system enzymes.

Alexis Battleمشاهده پروفایل

دانشیار

• Genomics
• Machine Learning
• Computational Biology
• +۳ مورد دیگر

Alexis Battle is an Associate Professor at Johns Hopkins University with appointments in Biomedical Engineering , Computer Science , and Genetic Medicine (secondary). She directs the Malone Center for Engineering in Healthcare and serves as Deputy Director of the Data Science and AI Institute . Educated at Stanford University (PhD in Computer Science, 2013), Battle transitioned to academia after leadership roles at Google. Research Focus: Battle’s work bridges genomics and machine learning , emphasizing the impact of genetic variation on human health. Her lab develops tools like Watershed to predict functional effects of rare variants, aiming to enhance rare disease diagnosis. Key themes include non-coding DNA analysis , personalized genomics , and systems biology , with applications in cardiovascular disease and neurodegenerative disorders . Publications & Awards: Over 60 peer-reviewed articles in journals like Nature , Science , and Genome Biology , with recent emphasis on single-cell transcriptomics , multiomics integration , and telomere biology . Recipient of the President’s Frontier Award (2022), Microsoft Investigator Fellowship (2019), and Searle Scholar (2016). Scientific Awards: 2022 President’s Frontier Award 2019 Microsoft Investigator Fellowship 2019 Johns Hopkins Discovery Award 2017 Johns Hopkins Catalyst Award 2016 Searle Scholar Advising & Funding: Mentors 11 PhD students, 3 undergraduates, and postdoctoral fellows. Her research is funded by NIH, Searle Scholars, and institutional grants. The Battle Lab collaborates on projects like the GTEx Consortium , focusing on gene regulation and clinical genomics .

Yaojun Zhangمشاهده پروفایل

استادیار

• Biological Physics
• Biophysics
• Theoretical Physics
• +۳ مورد دیگر

Yaojun Zhang is an Assistant Professor in the Department of Physics & Astronomy and the Department of Biophysics at Johns Hopkins University. She earned her PhD in Physics from the University of California, San Diego (2015), followed by postdoctoral fellowships at the Princeton Center for Theoretical Science (2015-2018) and the Princeton Center for the Physics of Biological Function (2018-2021). Her research focuses on biological physics, particularly the complex behaviors of biomolecules and their assemblies across scales—from single-molecule folding to intracellular transport and biomolecular phase separation. She employs theoretical, mathematical, and computational tools to bridge biological questions with physical principles. Education PhD in Physics, University of California, San Diego (2015) Postdoctoral Fellowships: Princeton University (2015-2021) Research Interests Her group studies biomolecular condensates and liquid-liquid phase separation, exploring how microscopic interactions determine macroscopic properties of cellular compartments. Key areas include: Biomolecular condensate formation and dynamics Phase separation in cellular environments Interactions between biomolecules and cellular components Biophysics of intracellular transport Collaborations & Tools Zhang collaborates with experimentalists to validate theoretical models and develops frameworks for understanding condensate functions, such as surface tension, stoichiometry, and phase diagrams. Her work addresses challenges like condensate stability, molecular exclusion, and biological function regulation. Labs & Resources She leads the Zhang Lab , which integrates experimental and computational approaches. Her team’s research is supported by resources at the Bloomberg Center for Physics and Astronomy.

Andre Levchenkoمشاهده پروفایل

استاد

• Systems Biology
• Signal Transduction
• Cell Communication
• +۵ مورد دیگر

Andre Levchenko is the John C. Malone Professor of Biomedical Engineering at Yale University, with secondary appointments in the Department of Neurosurgery and affiliations with the Cancer Signaling Networks, Immunology, and the Yale Program in Neurodevelopment and Regeneration. His research focuses on systems biology, signal transduction, and cell-cell communication, utilizing microfluidics and computational modeling to study cancer progression, stem cell behavior, and neurological disorders. PhD, Columbia University MEng, Moscow Institute of Physics and Technology Levchenko's work explores how cells process dynamic signals to make critical decisions, particularly in glioblastoma migration, organoid development, and cardiovascular tissue engineering. His lab develops innovative microfluidic platforms and mathematical models to dissect multicellular communication and signaling networks. Recent publications highlight his contributions to understanding YAP-driven cancer invasion , NOTCH signaling in angiogenesis , and metabolic regulation of hypoxia responses . He has pioneered methods for organoid modeling and single-cell analysis , advancing precision in biological signaling studies. Scientific Awards : Computational Molecular Biology Post-Doctoral Fellowship (Burroughs Wellcome Fund) National Academies Keck Futures Conference Invitee Distinguished Guest Lecturer, University of Virginia American Asthma Foundation Early Excellence Award Fellow, American Institute for Medical and Biological Engineering Levchenko leads the Levchenko Lab at the Yale Systems Biology Institute, collaborating with institutions like Mayo Clinic and Yale Cancer Center. His research has received recognition in Faculty of 1000 and multiple journal highlights.

Malte Oppermannمشاهده پروفایل

استاد

• Ultrafast spectroscopy
• Chiral dynamics
• Molecular dynamics
• +۴ مورد دیگر

Prof. Dr. Malte Oppermann is a full Professor at the University of Basel , leading the Ultrafast Chiral Dynamics Laboratory within the Department of Chemistry. His group specializes in developing cutting-edge time-resolved spectroscopic techniques to probe molecular transformations on femtosecond to microsecond timescales, focusing on chirality and structural dynamics in complex systems. Research Focus: Ultrafast Chiral Spectroscopy : Using circularly polarized laser pulses to resolve structural changes in chiral systems. Molecular Motors & Protein Dynamics : Capturing conformational changes in synthetic motors and proteins in native environments. Photoactive Materials : Investigating light-energy conversion mechanisms in chiral photochemical systems. His research bridges physics and chemistry, employing state-of-the-art laser technology and collaborating internationally across synthesis, spectroscopy, and theory. Publications & Impact: Prof. Oppermann’s work (2011–2025) spans ultrafast spectroscopy , chiral dynamics , nanomaterials , and biomolecular photophysics . Key themes include spin-crossover dynamics, DNA photodamage, and plasmonic nanoparticles, with techniques like transient X-ray absorption and deep-UV circular dichroism. Team & Opportunities: The group actively recruits MSc/PhD students and postdocs in physics, chemistry, and materials science. Interested candidates are encouraged to contact Prof. Oppermann directly.

• RNA Biology
• Myeloid Malignancies
• Hematology
• +۴ مورد دیگر

Dr. Giulia Biancon is an Assistant Professor Adjunct in the Department of Medical Oncology and Hematology at Yale School of Medicine. She holds a PhD from the University of Milan (2019) and is a member of the Halene Lab, focusing on RNA biology and hematologic malignancies. Her research combines high-throughput methodologies to study RNA mechanisms in diseases like myeloid leukemias and splicing factor mutations. Education: PhD in Molecular Biology from the University of Milan (2019). Research Interests: RNA splicing, stress granules in cancer, epitranscriptomics, clonal hematopoiesis, and the interplay between genetic mutations and cellular pathways in blood cancers. Awards: 2024 Eclipse Award, 2022 ASH Abstract Achievement Award, and 2022 RNA Society Best Poster Award. Her work has been published in journals like Cell Reports , Blood , and Molecular Cell . Labs/Teams: Principal member of the Halene Lab and coordinator at the Yale Center for RNA Science and Medicine. Collaborates with institutions like the SeroNet network for immunology studies.

Gary Pielakمشاهده پروفایل

استاد

• Protein Biophysics
• In-Cell NMR Spectroscopy
• Macromolecular Crowding
• +۳ مورد دیگر

Gary Pielak is a Kenan Distinguished Professor of Chemistry, Biochemistry, and Biophysics at the University of North Carolina at Chapel Hill, with a joint appointment in the School of Medicine. His research focuses on high-resolution protein NMR studies in living cells and the biophysics of tardigrade desiccation-tolerance proteins, bridging structural biology and molecular biophysics. Education: BS in Chemistry from Bradley University (1977), PhD in Biochemistry from Washington State University (1983), Postdoc at the University of British Columbia (1983-1986), Postdoc at Oxford University (1986-1988). Research Interests center on understanding protein structure, stability, and function in physiologically relevant environments. Key areas include: In-Cell NMR: Quantifying protein behavior in living cells using advanced NMR techniques. Macromolecular Crowding: Studying synthetic polymers and proteins as crowding agents to mimic cellular environments. Tardigrade Biology: Exploring desiccation-tolerance mechanisms in intrinsically disordered proteins from water bears. Recent Publications highlight interdisciplinary trends, combining AI-driven stability prediction, solid-state NMR for dry protein analysis, and molecular glass/gel applications for preservation. His Scientific Awards include: NIH Pioneer Award DuPont and Morrow Young Faculty Awards Multiple UNC Mentorship Awards Mentorship is a cornerstone, with a focus on training graduate students and advancing NMR methodologies. His group employs Research Methods : 19F, 1H, 15N, and 13C NMR Circular Dichroism and Calorimetry Protein Expression in E. coli

Kristian Helinمشاهده پروفایل

استاد

• Cancer biology
• Epigenetics
• Stem cells
• +۵ مورد دیگر

Kristian Helin is Chief Executive and President of The Institute of Cancer Research (ICR), London, and a Professor with affiliations at the University of Copenhagen and Memorial Sloan Kettering Cancer Center. He founded/directed the Biotech Research & Innovation Centre (BRIC), Centre for Epigenetics, and Danish Stem Cell Center. His research focuses on epigenetic regulation, cancer biology, and stem cell differentiation. Education: Ph.D. Molecular Biology, University of Copenhagen (1991) M.Sc. Chemical Engineering, Technical University of Denmark (1988) Research Interests: Helin's work deciphers molecular mechanisms in cancer, emphasizing epigenetic drivers (e.g., H3K4/H3K36 methylation), transcriptional control, and therapeutic targeting. His lab identified E2F transcription factors, linked epigenetic dysregulation to leukemia/lymphoma, and develops drugs targeting kinases/epigenetic enzymes. Research spans acute myeloid leukemia, B-cell lymphoma, and solid tumors using CRISPR screens and preclinical models. Publication Trends: Recent articles (2023-2025) focus on epigenetic therapy, chromatin remodeling, and kinase signaling in cancer. Key themes include targeting NSD1/KDM5C/RIOK2 enzymes, combination therapies (EZH2/DOT1L inhibitors), and metabolic regulation in leukemia. Studies bridge basic mechanisms (enhancer regulation, insulator accessibility) with translational applications. Awards: Anders Jahre Prize (2014), ERC Advanced Grant (2011), Novo Nordisk Prize (2008) Memberships: Academia Europaea, Royal Danish Academy, EMBO Leadership: Helin co-founded EpiTherapeutics (acquired by Gilead) and leads the Epigenetics and Cancer lab at ICR. His team investigates AML pathogenesis and chromatin complexes like HUSH/NURF. Grants include ERC funding and innovation prizes.

• Protein Degradation Pathways
• Ubiquitin-Proteasome System
• Pendrin Mutations
• +۲ مورد دیگر

Florian Huber is a Research Associate at Paracelsus Medical University's Institute of Pharmacology and Toxicology, investigating molecular mechanisms of genetic hearing disorders. His work focuses on ubiquitin-proteasome regulation of pendrin (SLC26A4) variants associated with Pendred syndrome. Recent studies demonstrate how proteasome inhibitors rescue function of pathogenic pendrin mutants, offering therapeutic pathways for hearing restoration. Huber develops experimental and computational approaches to map degradation pathways of membrane transport proteins. He supervises medical doctoral candidates and teaches pharmacology in graduate programs.

Thomas R Overtonمشاهده پروفایل

استاد

• Dairy Cattle Nutrition
• Transition Cow Management
• Metabolic Health of Dairy Cows
• +۳ مورد دیگر

Thomas R Overton serves as Department Chair and Professor of Dairy Nutrition and Management in the Department of Animal Science at Cornell University's College of Agriculture and Life Sciences (CALS). He also directs PRO-DAIRY, an extension program focused on enhancing dairy farm profitability and efficiency in New York through research-based strategies for transition cow management. Education: Doctorate, University of Illinois, 1998 Master of Science, University of Illinois, 1994 Bachelor of Science, Cornell University, 1991 Dr. Overton's research centers on the transition period (late pregnancy to early lactation) in dairy cows—the most critical phase for health and productivity. His work integrates nutritional physiology with practical farm applications, targeting hypocalcemia management, protein supplementation strategies, inflammation control, and biomarker validation for metabolic health. This research directly informs his extension efforts through PRO-DAIRY, which delivers actionable knowledge to dairy producers and industry professionals. Analysis of his 15 most recent publications (2022-2024) reveals consistent emphasis on transition cow nutrition, with growing focus on metabolic analytics, precision feeding, and real-world herd management. His work bridges controlled studies at Cornell's Ruminant Center with observational research on commercial New York dairy farms. Scientific Awards: 2024 Nutrition Professionals Applied Dairy Research Award (American Dairy Science Association) 2010 CALS Extension/Outreach Team Award (PRO-DAIRY) 2007 Foundation Scholar Award (American Dairy Science Association) 2007 CALS Extension/Outreach Team Award Dr. Overton advises undergraduate and graduate students in Animal Science while leading PRO-DAIRY's extension initiatives. His program secures industry partnerships and grants focused on improving dairy farm sustainability through nutritional science. The July 2025 'Farm of the Future' showcase at Cornell's Ruminant Center exemplifies his commitment to translating research into practical innovation. He operates within Cornell's PRO-DAIRY program and the Cornell University Ruminant Center—a living laboratory for dairy technology testing—collaborating closely with industry stakeholders to address emerging challenges in dairy production.

• Natural Products Chemistry
• Medicinal Chemistry
• Biosynthesis
• +۴ مورد دیگر

David H. Sherman is the Hans W. Vahlteich Professor of Medicinal Chemistry at the University of Michigan, holding joint appointments in the College of Pharmacy (Department of Medicinal Chemistry), Medical School (Microbiology & Immunology), and College of Literature, Science, and the Arts (Chemistry). He leads the Sherman Lab at the Life Sciences Institute and co-founded the Natural Products Discovery Core. His research focuses on natural product discovery, biosynthetic pathways, and drug development for infectious diseases, cancer, and neurological disorders. Education: PhD in Synthetic Organic Chemistry from Columbia University (1981), BA in Chemistry from UC Santa Cruz (1978). Postdoctoral research at MIT (1984). Research interests include microbial secondary metabolites, enzymatic catalysis (e.g., C-H functionalization, polyketide assembly), and high-throughput drug screening. He pioneered a microbial natural product library with over 50,000 samples. Current projects emphasize developing macrolide antibiotics and advancing compounds toward clinical trials through the Natural Products Biosciences Initiative. Collaborations span global institutions, with a focus on biodiversity conservation and capacity-building in low-income nations. He has mentored 67 PhD students, 60 postdocs, and 85+ undergraduates, fostering interdisciplinary training in chemical biology and microbial biochemistry. Labs/Teams: Sherman Lab (Life Sciences Institute), Center Member at Samuel and Jean Frankel Cardiovascular Center, Center for Computational Medicine and Bioinformatics, Rogel Cancer Center.

Thibault Mayorمشاهده پروفایل

استاد

• Protein Homeostasis
• Ubiquitin Proteasome System
• Neurodegenerative Diseases
• +۷ مورد دیگر

Thibault Mayor is a Professor in the Department of Biochemistry and Molecular Biology and the Michael Smith Laboratories at the University of British Columbia (Vancouver). His research focuses on understanding how cells manage misfolded proteins, with implications for neurodegenerative diseases like Parkinson's and Alzheimer's. He holds academic affiliations with the Centre for High-Throughput Biology (CHiBi) and has been recognized with awards including the UBC Killam Teaching Award (2020). Education: BSc, University of Geneva, Switzerland (1997) PhD, University of Geneva & Max Planck Institute of Biochemistry, Germany (2001) Postdoctoral Fellow, California Institute of Technology (2002) Research Interests: Mayor's lab investigates protein homeostasis, ubiquitin-proteasome system dynamics, and the molecular mechanisms underlying protein aggregation in aging and disease. Projects include proteomic approaches to identify aggregation-prone proteins and develop microbial cell factories for protein production. Grants & Awards: CIHR Project Grant ($730K, 2018) Michael Smith Foundation Career Award (2012) UBC Killam Teaching Award (2020) Labs & Collaborations: The Mayor Lab is part of the Michael Smith Laboratories and collaborates with computational biologists like Jörg Gsponer. They maintain active partnerships in proteomics and systems biology, contributing to initiatives like the BC Proteomics Network.

Britt Adamsonمشاهده پروفایل

دانشیار

• Stress Response Networks
• DNA Damage Response
• Genome Editing
• +۳ مورد دیگر

Britt Adamson is an Associate Professor in the Department of Molecular Biology and the Lewis-Sigler Institute for Integrative Genomics at Princeton University, where she serves as Director of the Undergraduate Program in Quantitative and Computational Biology. Her lab investigates molecular networks in human cells with focus on stress response mechanisms and genome editing technologies. She received her B.S. in Biology from the Massachusetts Institute of Technology (2005) and Ph.D. in Genetics and Genomics from Harvard University (2012), followed by postdoctoral training at UCSF under Jonathan Weissman supported by a Damon Runyon Cancer Research Foundation Fellowship. Adamson's research centers on how cells organize stress response networks during DNA damage and endoplasmic reticulum stress, developing CRISPR-based functional genomics and single-cell sequencing tools to map molecular behaviors. Her work bridges fundamental cell biology with therapeutic applications in genome editing. Analysis of her 15 most recent publications reveals dominant themes in precision genome editing (prime/base editing optimization) and systematic dissection of DNA repair pathways through combinatorial CRISPR screening. Her lab consistently integrates computational approaches with high-resolution experimental techniques to uncover context-dependent cellular behaviors. Her scientific recognitions include: Damon Runyon Cancer Research Foundation Postdoctoral Fellowship Princeton IP Accelerator Award (2025) STAT Who to Know: 10 Scientists leading a new generation of gene editors (2024) Adamson actively mentors eight graduate students (including alumni Ann Cirincione and Jun Hussmann) and two postdocs, with research funded through institutional awards and collaborative grants. Her lab's technological developments have enabled projects spanning virology, immunology, and developmental biology. The Adamson Lab operates within Princeton's Lewis-Sigler Institute for Integrative Genomics, fostering an interdisciplinary environment that merges cell biology, genomics, and computational science. Current projects focus on improving prime editing efficiency and understanding stress response adaptation in disease contexts.