Diffuse Axonal Injury Professors and Supervisors

Tammie Benzingerمشاهده پروفایل

استاد

Washington University in St. LouisUnited States

Tammie Benzinger, MD, PhD is the Hugh Monroe Wilson Professor in the Department of Radiology at Washington University School of Medicine in St. Louis. She serves as the Director of the Knight Alzheimer Research Imaging (KARI) Program and is the Imaging Core Leader for the Dominantly Inherited Alzheimer Network (DIAN) and DIAN-Therapeutic Unit. Dr. Benzinger leads the Benzinger Lab, which focuses on developing PET and MRI methods for studying central nervous system diseases. Dr. Benzinger completed her MD and PhD at the University of Chicago, where her graduate work demonstrated the first evidence for a parallel beta-sheet structure for Ab fibrils. She completed her radiology residency at Washington University, focusing on translational human MRI. Her research spans Alzheimer's disease biomarkers, neuroinflammation imaging, tau pathology, and advanced neuroimaging techniques for both neurodegenerative diseases and brain tumors. Her lab's work has established critical biomarker trajectories in Alzheimer's disease progression, particularly through the DIAN initiative. The Benzinger Lab has developed numerous imaging techniques including diffusion basis spectrum imaging (DBSI) for detecting neuroinflammation and novel PET approaches for amyloid and tau imaging. They maintain the OASIS-3 database with over 2000 MRI scans from more than 1000 research participants. Dr. Benzinger has served as Principal Investigator on multiple NIH-funded projects including the Adult Children's Study (ACS) and Healthy Aging and Senile Dementia (HASD) studies. Her work has been published in top journals including PNAS, Nature Neuroscience, Brain, and Lancet Neurology, with several papers accumulating hundreds of citations. NIH/NIA P50AG05681 (ADRC Center Grant) 1R01AG054567-01A1 2R01NS103988-06A1 1RF1AG064937-01 R01AG052550-01A1 Dr. Benzinger collaborates extensively with researchers including Yong Wang, Beau Ances, Matthew Brier, Anne Cross, Brian Gordon, and other leading Alzheimer's disease researchers. She also participates as a site investigator in clinical trials sponsored by pharmaceutical companies including Eli Lilly, Biogen, Eisai, Janssen, and Roche, and has served as a consultant to several of these companies.

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Joshua R. Olexaمشاهده پروفایل

استادیار بالینی

University of Maryland, BaltimoreUnited States

Joshua R. Olexa, MD, MBA is a Clinical Assistant Professor in Neurosurgery with expertise in complex spine surgery and general cranial neurosurgery. His clinical focus spans spinal tumors, trauma, degenerative conditions, and minimally invasive techniques, while embracing emerging technologies like augmented reality (AR) and image-guided navigation. Research interests include: Augmented reality applications in neurosurgical planning Spinal oncology and trauma management Blood pressure variability in traumatic brain injury Intraoperative imaging techniques Neurocritical care optimization Recent publications (2025–2023) emphasize AR-integrated surgical tools, spinal vascular anomalies, intracranial pressure dynamics, and outcome predictors in hemorrhagic stroke. His work bridges technological innovation with clinical neurosurgery.

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Charles A. Sansurمشاهده پروفایل

استاد

University of Maryland, BaltimoreUnited States

Charles A. Sansur is a Professor of Neurosurgery at the University of Maryland School of Medicine, serving as Director of Spine Surgery for the Department of Neurosurgery. He holds secondary appointments in Orthopaedics and maintains clinical practice at the University of Maryland Medical Center (UMMC), South Hospital, S-12-D. Nationally recognized as a spine surgery expert, he frequently lectures at prominent societies including the American Association of Neurological Surgery and Congress of Neurological Surgeons. University of Pennsylvania, B.A. 1996 (Magna Cum Laude with Distinction) University of Maryland School of Medicine, M.D. 2002 Duke University/NIH, MHSc in Clinical Research 2002 Neurosurgery Residency: University of Virginia Medical Center (2003-2008) Spine Fellowships: Auckland City Hospital (2006-2007), University of Virginia (2008-2009) Dr. Sansur specializes in complex spine pathologies including spinal deformity, degenerative disease, spinal oncology, and spine trauma. His research focuses on spine outcome studies, spinal deformity correction, scoliosis management, and trauma interventions. He has pioneered techniques for conditions requiring specialized care unavailable in community settings, particularly in global sagittal deformity correction and complex spinal oncology. His work emphasizes evidence-based approaches to surgical decision-making in elderly patients with degenerative conditions. Analysis of his 250+ publications reveals consistent focus on large-scale outcome studies, with seminal contributions to understanding morbidity/mortality in adult scoliosis (10,242-patient study) and spondylolisthesis (10,329-patient study). His research leverages multi-institutional collaborations through the Scoliosis Research Society, emphasizing practical metrics like unintended durotomy rates (108,478-case analysis) and thromboembolism risks. Russell A. Hibbs Best Clinical Science Award, Scoliosis Research Society (2009) Baltimore Veterans Hospital Gold Pin Award for clinical excellence (2010) As Director of Spine Surgery, Dr. Sansur oversees complex surgical cases and leads research initiatives involving biomechanical studies, novel instrumentation, and outcome assessment. His current work explores augmented reality applications, sacroiliac joint fusion predictors, and advanced dural repair techniques. He serves on the Scoliosis Research Society Morbidity and Mortality Committee, driving national quality improvement efforts.

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Melissa Mottaمشاهده پروفایل

دانشیار

University of Maryland, BaltimoreUnited States

Melissa Motta is an Associate Professor in the Department of Neurology at the University of Maryland School of Medicine, specializing in neurocritical care and stroke management. She serves as Director of the Neurology Clerkship and leads initiatives in medical education and patient-family engagement. MD and MPH from George Washington University Neurology Residency and Fellowship at Johns Hopkins Hospital Certificate in Clinical Investigation (Bloomberg School of Public Health) Her research focuses on improving quality of life for neurological patients through patient-reported outcomes and family-centered care. She established a Neuro Recovery Clinic for post-ICU rehabilitation and implemented evidence-based strategies across University of Maryland ICUs. Fields include neurointensive care , stroke , health services research , and patient engagement . Recent work spans neurotrauma , prognostic communication , and multidisciplinary recovery models , with publications in Neurology , Crit Care Med , and Neurohospitalist . Her 2015 study on diffusion-perfusion mismatch in stroke highlights neuroimaging applications. NINDS R25 Research Education Grant Dr. Motta mentors through medical education curricula and collaborates on patient-centered care frameworks. Her Neuro Recovery Clinic integrates guideline-driven care for post-critical illness recovery. She contributes to the Society of Critical Care Medicine's patient-centered research initiatives.

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Jamie E. Podellمشاهده پروفایل

استادیار

University of Maryland, BaltimoreUnited States

Jamie E. Podell, MD is an Assistant Professor in the Department of Neurology at the University of Maryland School of Medicine, specializing in neurocritical care with clinical expertise at the R. Adams Cowley Shock Trauma Center. His work focuses on traumatic brain injury (TBI), paroxysmal sympathetic hyperactivity (PSH), and autonomic dysfunction in critically ill neurological patients. Education 2008: B.A. in Cognitive Science (with distinction, cum laude), Yale College 2014: M.D., Perelman School of Medicine, University of Pennsylvania 2008-2010: Intramural Research Training Award (IRTA) Fellow, National Institutes of Mental Health 2014-2015: Intern in Internal Medicine, Hospital of the University of Pennsylvania 2015-2018: Resident in Neurology, Hospital of the University of Pennsylvania 2018-2020: Fellow in Neurocritical Care, University of Maryland Medical Center/Shock Trauma Research Focus Dr. Podell's research integrates neurocritical care , autonomic physiology , and advanced analytics to address TBI complications. Key areas include: machine learning for prognostication in diffuse axonal injury; dual-energy CT for predicting cerebral edema; continuous physiologic monitoring of autonomic dysfunction; and management of paroxysmal sympathetic hyperactivity. His work bridges neuroimaging, physiologic modeling, and neuromodulation to develop automated severity assessment tools. Publication Trends His 2023-2025 publications reveal three dominant themes: (1) Machine learning applications for TBI outcome prediction using lesion segmentation and physiologic data; (2) Advanced neuroimaging techniques (dual-energy CT, diffusion kurtosis MRI) to identify biomarkers of neurological decline; (3) Clinical management of autonomic dysfunction, particularly PSH in TBI patients. This work consistently emphasizes real-time monitoring and data-driven interventions in neurocritical care. Scientific Recognition Intramural Research Training Award (IRTA) Fellow, National Institutes of Mental Health (2008-2010) Clinical & Educational Activities Dr. Podell contributes to neurocritical care education through simulation-based training for neurological emergencies, including post-cardiac arrest resuscitation and acute stroke management. His work on disorders of consciousness assessment and neurorecovery clinics demonstrates commitment to translational care. While specific grants aren't detailed, his machine learning and physiologic modeling research suggests active collaboration with data science groups. Clinical Affiliations He is embedded within the University of Maryland's neurocritical care ecosystem, working closely with the Shock Trauma Center's neurotrauma team and the Center for Brain Injury and Repair. His research leverages the institution's high-volume trauma data for developing predictive models in TBI management.

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Edward A Dauerمشاهده پروفایل

استاد بالینی

University of MiamiUnited States

Edward A Dauer is a Clinical Professor in the Department of Biomedical Engineering at the College of Engineering, University of Miami. His work spans biomedical and civil engineering disciplines, focusing on biomaterials development and material science applications. Biomedical Engineering: Scaffold design for immunomodulation and peripheral nerve repair Civil Engineering: Protein-modified biocementation and nanoparticle-reinforced construction materials His research in biomedical engineering includes 3D scaffold fabrication for fibroblastic reticular cell maintenance and autoimmune therapy, while environmental applications involve electrohydromodulation for phosphate recovery. Material science work covers Kevlar composites and Polyurethane scaffold characterization, with biocementation studies analyzing protein effects on calcium carbonate precipitation. Publication trends show expertise in interdisciplinary material design , with articles covering topics from diabetogenic T cell modulation to bioremediation and composite durability . Key methodologies include scaffold fabrication, electrochemical recovery systems, and microstructural analysis across biological and civil engineering applications.

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Kacy Cullenمشاهده پروفایل

استاد

University of PennsylvaniaUnited States

D. Kacy Cullen is a Professor of Neurosurgery and Bioengineering (with tenure) at the Perelman School of Medicine, University of Pennsylvania. He serves as Principal Investigator at the Corporal Michael J. Crescenz VA Medical Center in Philadelphia and holds multiple leadership positions including Director of the Center for Neurotrauma, Neurodegeneration & Restoration at the VA Medical Center, Director of the Translational Tissue Engineering & Regenerative Medicine Fellowship Program, and Director of the Porcine Neurointensive Care and Assessment Facility. Dr. Cullen's educational background includes: B.S. in Mechanical Engineering from Georgia Institute of Technology (2000) M.S. in Mechanical Engineering from Georgia Institute of Technology (2002) Ph.D. in Biomedical Engineering from Georgia Institute of Technology (2005) Dr. Cullen's research program operates at the intersection of three complementary fields: Regenerative Medicine , Neural Engineering , and Neurotrauma . In Regenerative Medicine, his lab focuses on novel biofabrication strategies for tissue engineered brain and spinal cord pathways as well as "living scaffolds" for neuroregeneration. His Neural Engineering work develops "biohybrid" neuroprosthetic interface technology and enables synaptically-based neuromodulation. In Neurotrauma research, he applies engineering principles to understand causative mechanisms and pathophysiological responses following traumatic injury to the nervous system, with specific attention to neural injury biomechanics. Analysis of Dr. Cullen's recent publications reveals a strong focus on tissue-engineered neural constructs for repairing nervous system injuries. His work spans from fundamental research on neural injury mechanisms to translational applications of tissue engineering for nerve repair, spinal cord injury, and Parkinson's disease. A notable trend is the development of "living scaffolds" and "biohybrid" neural interfaces that combine biological and engineered components. His research increasingly incorporates large animal models, particularly swine, to enhance translational relevance. Dr. Cullen's laboratory has received significant funding from multiple prestigious sources including the Department of Veterans Affairs, the National Institutes of Health, the Department of Defense, and the University Research Foundation at the University of Pennsylvania. He directs the Translational Tissue Engineering & Regenerative Medicine (T-TERM) Fellowship Program, which is jointly supported by the Department of Veterans Affairs and the University of Pennsylvania. Dr. Cullen leads the Cullen Lab, which operates the Porcine Neurointensive Care and Assessment Facility (NCAF) at the Perelman School of Medicine. His lab applies biomedical engineering principles toward understanding neural injury mechanisms and developing neural tissue engineering-based treatments. The lab maintains active collaborations with multiple research centers including the Penn Center for Brain Injury & Repair, the Penn Center for Musculoskeletal Disorders, the Institute of Regenerative Medicine, and the Institute for Translational Medicine and Therapeutics.

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Michel J.A.M. van Puttenمشاهده پروفایل

استاد

University of TwenteNetherlands

Michel J.A.M. van Putten is a Full Professor of Clinical Neurophysiology at the TechMed Centre, University of Twente , with an h-index of 52 and 9261 Scopus citations. His research focuses on: EEG-based outcome prediction in post-cardiac arrest coma Deep learning applications for seizure and interictal discharge detection Neurophysiological modeling of epilepsy and traumatic brain injury Cultured cortical neural networks for disease mechanism inference AI-driven analysis of brain connectivity and excitation-inhibition balance His work contributes to UN Sustainable Development Goals for Health and Well-being , Human-AI Interaction , and Economic Impact of AI . Recent research includes: 2025: Automated inference of disease mechanisms in patient-derived neuronal networks 2025: Expert-level deep neural network for interictal discharge detection 2024: Grassmann manifold methods for invariant EEG/MEG feature extraction Scientific recognition includes: 2011: NVvTG Congres Prize 2012: Tripartite prize for Near Infrared Spectroscopy and EEG research His datasets on EEG analysis and cortical network modeling are publicly available through Zenodo, and he has presented 17 oral presentations on topics including: Post-ictal brain recovery mechanisms Mathematical models of peripheral axons Ischemic cerebral damage pathways

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Susan C Schwerinمشاهده پروفایل

عضو هیئت علمی

Uniformed Services University of the Health SciencesUnited States

Susan C. Schwerin is a Research Assistant Professor in the Department of Anatomy, Physiology and Genetics at the Uniformed Services University of the Health Sciences School of Medicine in Bethesda, Maryland. With over a decade of experience at the institution, she has established herself as a specialist in traumatic brain injury research using gyrencephalic animal models. Her educational background includes: PhD in Neuroscience from Northwestern University Institute for Neuroscience (2005) Postdoctoral Fellowship in Neuroscience at the University of Florida (2006-2009) Postdoctoral Fellowship in Neuroscience at Uniformed Services University (2009-2013) BS in Biological Sciences from Michigan Technological University (1995) Dr. Schwerin's research primarily focuses on traumatic brain injury and neuroplasticity, with particular expertise in developing and utilizing ferret models for studying brain trauma. Her work bridges experimental neuroscience with clinical applications, investigating how brain injuries affect neural pathways and behavioral outcomes. She has made significant contributions to understanding the progression of histopathological and behavioral abnormalities following mild traumatic brain injury. Her publication record shows a consistent trajectory of high-impact research in neuroimaging techniques, particularly diffusion MRI and DTI, for detecting brain alterations following injury. Her work spans from basic methodology development (creating population-based MRI templates for ferret brains) to clinical applications (studying sleep disruption and motor recovery patterns). The research demonstrates a strong emphasis on translational neuroscience, with findings that have implications for human traumatic brain injury diagnosis and treatment. Dr. Schwerin's collaborative approach is evident in her extensive publication record, working with researchers across various disciplines including neuroimaging, neurophysiology, and rehabilitation science. Her work on ferret models has established this species as a valuable gyrencephalic model for studying traumatic brain injury, filling an important gap between rodent models and human studies.

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