- Mass Spectrometry
- Metabolomics
- Lipidomics
- +۵ مورد دیگر
Zheng-Jiang Zhu is a Professor at the Shanghai Institute of Organic Chemistry (SIOC), Chinese Academy of Sciences, within the Interdisciplinary Research Center on Biology and Chemistry (IRCBC) . Since 2013, he has led a research program focused on advanced mass-spectrometry technologies and their application to metabolomics, lipidomics, and systems biology. Education and Training PhD in Chemistry, University of Massachusetts Amherst, 2006–2011 BS in Chemistry, Nanjing University, 2002–2006 Post-doctoral Research Associate, Scripps Research Institute, 2011–2013 Research Interests Professor Zhu’s research integrates cutting-edge mass spectrometry , ion mobility spectrometry , and bioinformatics to address fundamental questions in metabolism , aging , and neurodegeneration . His group develops novel analytical workflows, software tools, and databases that enable high-throughput, high-coverage profiling of metabolites and lipids in complex biological systems. Specific areas of focus include: Stable-isotope tracing metabolomics for mapping metabolic fluxes across tissues Lipid transport and remodeling at subcellular resolution Machine-learning-assisted metabolite annotation and structural elucidation Biomarker discovery for early cancer diagnosis and aging interventions Scientific Output & Impact Over the past decade, Zhu has authored more than 78 peer-reviewed publications in leading journals such as Nature Communications , Analytical Chemistry , Science Advances , and Nature Chemistry . His 2025 papers alone address tissue-specific fatty-acid biosynthesis, AI-driven metabolite annotation, organellar lipid trafficking, and the anti-aging role of citrulline in macrophages. These works collectively advance both technological frontiers and biological understanding, positioning his laboratory at the forefront of integrated multi-omics research. Software & Databases AllCCS2 – A curated atlas of collision cross-section values for small molecules Met4DX – A unified data-processing platform for multidimensional untargeted metabolomics LipidIMMS Analyzer – Integrative tools for ion-mobility-based lipidomics MetFlow – Interactive workflow for metabolomics data cleaning and differential analysis Collaborations & Funding Zhu’s research is supported by multiple national grants and extensive collaborations with clinicians and industry partners. His group routinely engages in peer review for over 20 high-impact journals, reflecting the community’s recognition of his expertise in analytical chemistry and systems biology.









