Frédéric Lesage is a Full Professor in the Department of Electrical Engineering at Polytechnique Montréal and holds a Tier 1 Canada Research Chair in Vascular Optical Imaging. His multidisciplinary research bridges biomedical engineering, neuroscience, and AI, with affiliations spanning the Functional Imaging Laboratory (INSERM), Montreal Heart Institute, and Centre for Mathematical Research. Research interests center on neuroimaging innovations for studying cerebral physiology. Key areas include: Neurovascular Coupling: Investigating blood flow dynamics in aging and Alzheimer's using optical coherence tomography and NIRS. Epilepsy Diagnostics: Developing AI models for seizure prediction via EEG/fNIRS fusion. Microvascular Pathologies: Mapping microstroke impacts using two-photon microscopy and adversarial learning. His 15 most recent publications (2020-2025) emphasize AI-driven neurology applications, showing trends in: Machine learning for epileptic EEG analysis Cerebral pulsatility in neurodegenerative diseases Translational vascular imaging (OCT/TPM) Awards include the Canada Research Chair (Tier 1) , renewed in 2022 for pioneering vascular imaging techniques. He has advised 57+ graduate students (27 PhD, 30 Master's) and secured grants from NSERC, CIHR, and CRC. Current projects focus on hypoxia effects, statin therapy in Alzheimer's, and catheter-based surgical simulators.