جست‌وجوی استاد و پژوهشگر

• Organic Chemistry
• Medicinal Chemistry
• Bioorganic Chemistry
• +۷ مورد دیگر

Professor John Spencer is a Professor of Bioorganic Chemistry and Director of the Sussex Drug Discovery Centre within the School of Life Sciences at the University of Sussex. With a distinguished career spanning academia and the pharmaceutical industry, he leads a research group focused on innovative drug discovery approaches. His educational background includes a first-class honors degree from Sussex, a PhD from the University of Strasbourg (1990-1994), and postdoctoral studies at ETH Zurich. After 10 years in the pharmaceutical industry, he held academic positions first as Reader at Greenwich University (5 years) and then at the University of Sussex where he progressed from Reader to Professor. Professor Spencer's research spans organic synthetic methodology, fragment-based drug design, PROTAC development, and C-H activation chemistry with applications in cancer, neurodegenerative disorders, and infectious diseases. His work bridges fundamental chemical research with therapeutic applications, particularly in targeted protein degradation and novel drug delivery systems. Analysis of his recent publications (2023-2025) reveals a strong focus on structure-guided drug design, with significant contributions to PROTAC technology, fragment-based screening methods, and the development of novel therapeutic approaches for cancer and infectious diseases. His work frequently appears in high-impact journals including Nature Communications, Angewandte Chemie, and Journal of Medicinal Chemistry. Over 30 active and recent grants from major funding bodies including Wellcome Trust, EPSRC, Cancer Research UK, and industry partners Significant contributions to the Open Science discovery of SARS-CoV-2 main protease inhibitors Leadership in the Sussex Drug Discovery Centre infrastructure Professor Spencer actively supervises multiple PhD students and postdocs while maintaining strong industry collaborations. His advisory roles include the Prostate Cancer UK Research Advisory Committee (2023-2027) and previous service on the Worldwide Cancer Research advisory board. He teaches Bioorganic Chemistry (Year 3), Advanced Organic Chemistry (Year 4), and Advanced Medicinal Chemistry for MSc students. The Sussex Drug Discovery Centre under Professor Spencer's leadership serves as a hub for collaborative drug discovery research, connecting academic researchers with pharmaceutical industry partners to advance novel therapeutic approaches from concept to preclinical development.

• Electrochemistry
• Organic Chemistry
• Biochemistry
• +۳ مورد دیگر

Dr Jon Wilden serves as Associate Professor in Chemistry within the School of Life Sciences at the University of Sussex, where he leads research at the intersection of organic electrochemistry, bioimaging, and sustainable synthesis. His work bridges fundamental mechanistic studies with practical applications in pharmaceutical analysis and green chemistry. His research portfolio emphasizes: Electrochemical Methodology Development : Creating sustainable alternatives to traditional synthesis through electrochemical radical reactions, amide preparation, and copper acetylide formation Bioimaging Probe Design : Engineering BODIPY fluorophores with tailored spectroscopic properties for cellular imaging applications Mechanistic Elucidation : Using electrochemical and spectroscopic techniques to unravel reaction pathways in peptide modification and enzymatic processes Educational Innovation : Developing open-access computational resources for drug design education With over 60 publications since 2015, Professor Wilden's recent work (2020-2024) demonstrates increasing industrial relevance through therapeutic product analysis, patentable electrochemical methods, and educational resources adopted internationally. His publications consistently appear in high-impact chemistry journals with strong citation metrics, reflecting significant contributions to green chemistry and chemical education. He actively mentors graduate students through research projects in electrochemical synthesis and bioimaging, while securing research funding evidenced by consistent publication output. Though no dedicated laboratory name is specified, his research group operates within the Department of Chemistry's facilities, collaborating across disciplines to advance sustainable chemical methodologies.

• Organometallic Chemistry
• Phosphorus Chemistry
• Gold Chemistry
• +۵ مورد دیگر

Fernando López Ortiz is a Professor in the Department of Organic Chemistry at the University of Almería, where he leads the Organic and Organometallic Chemistry Research Group. With an extensive publication record of 163 articles and 16 doctoral theses supervised, he has established himself as a leading researcher in organometallic chemistry with particular expertise in phosphorus and gold chemistry. His research interests span multiple interconnected areas including organometallic synthesis, structural chemistry of phosphorus compounds, development of gold-based antimicrobial agents, and applications in catalysis and materials science. Professor López Ortiz has made significant contributions to understanding ortho-lithiated phosphinamides, cyclometallated gold complexes, and phosphorus-based multifunctional materials. His work bridges fundamental chemical principles with practical applications, particularly in addressing antimicrobial resistance through novel metal-based therapeutics. Analysis of his 15 most recent publications reveals a strong focus on gold chemistry for biomedical applications, with multiple papers on gold(III) complexes as antimicrobial and antiviral agents. He also maintains active research in phosphorus chemistry, publishing structural studies of phosphinothioic amides and novel phosphorus-containing compounds. A more recent direction involves energy applications, as evidenced by his 2025 paper on zinc-air batteries. h-index: 30 (Scopus and Web of Science) i10-index: 100 (Scopus) 163 peer-reviewed articles 16 doctoral theses supervised Multiple competitive research grants including EU Horizon 2020 funding As Principal Investigator on numerous research projects totaling over €1.5 million in funding, Professor López Ortiz has built a productive research program that trains graduate students while advancing knowledge in organometallic chemistry. His lab maintains active collaborations with microbiologists and pharmacologists to evaluate the biological activity of synthesized compounds, creating a rich interdisciplinary research environment. The Organic and Organometalic Chemistry Research Group under Professor López Ortiz's leadership focuses on synthesizing novel compounds with potential applications in medicine and technology, particularly targeting the growing challenge of antimicrobial resistance through innovative gold-based therapeutics and exploring sustainable energy solutions through advanced materials chemistry.

John Milliganمشاهده پروفایل

استادیار

• Organic Chemistry
• Photoredox Catalysis
• Radical Chemistry
• +۳ مورد دیگر

John Milligan serves as Assistant Professor in the Department of Chemistry within Thomas Jefferson University's College of Life Sciences. His research program centers on blue LED-driven photoredox catalysis for developing mild and efficient synthetic methodologies in organic chemistry. His educational background includes a Postdoctoral Scholar position at the University of Pennsylvania (2019), a PhD from the University of Pittsburgh (2018), and a BS from Allegheny College (2012). Milligan's primary research focuses on radical/polar crossover reactions to synthesize nitrogen heterocycles from unsaturated substrates, with particular emphasis on developing novel cyclopropanation strategies and heterocyclic frameworks. His group maintains an active intramural collaboration with Jefferson design experts to create 3D-printed devices for organic chemistry applications, bridging synthetic methodology with laboratory innovation. This work positions him at the intersection of photoredox catalysis, radical chemistry, and practical chemical tool development. Analysis of his publication record reveals three dominant research streams: (1) photoredox-mediated radical/polar crossover reactions for complex heterocycle synthesis, (2) development of strained molecule reagents (particularly bicyclobutanes), and (3) chemical education innovations including green laboratory experiments and pandemic-era remote teaching methodologies. His work demonstrates consistent methodology development within organic synthesis while addressing practical educational challenges. Scientific awards: No awards or fellowships were documented in the provided materials. Regarding academic mentorship, the source materials contain no explicit listings of current or former advisees. His educational publications suggest active curriculum development, particularly in laboratory safety and remote teaching adaptations, though specific grant funding details remain unreported. The intramural design collaboration indicates cross-disciplinary engagement beyond traditional chemistry boundaries. Milligan leads a research group actively developing 3D-printed laboratory apparatus through collaboration with Jefferson's design experts, demonstrating commitment to practical innovation in synthetic chemistry infrastructure. This initiative complements his fundamental research in photoredox catalysis and strained molecule chemistry.

• Polymer Science
• Materials Engineering
• Self-Healing Materials
• +۷ مورد دیگر

Nikhil K. Singha is a distinguished Professor in the Department of Polymer Science and Technology at the Indian Institute of Technology Kharagpur, India. With an impressive publication record of 220 documents, 8,688 citations, and an h-index of 44, he has established himself as a leading researcher in polymer science and materials engineering. His work spans multiple prestigious journals including ACS publications, European Polymer Journal, and Progress in Materials Science. Dr. Singha's research interests focus on advanced polymer materials, particularly in the areas of self-healing materials, Diels-Alder chemistry, elastomers, hydrophobic coatings, and green tire technology. His laboratory has pioneered innovative approaches to create smart materials with dynamic covalent networks, biomimetic adhesives, and environmentally friendly polymer solutions. The research demonstrates strong interdisciplinary connections between chemistry, materials science, and engineering applications. His recent publication trends (2021-2025) reveal a consistent focus on sustainable polymer technologies, with particular emphasis on self-healing mechanisms, hydrophobic surface engineering, and advanced elastomer systems. The work often combines fundamental polymer chemistry with practical applications in areas such as water purification, tire technology, and biomedical materials. Scientific Recognition: h-index of 44 8,688 citations from 6,867 documents Extensive publication record in high-impact journals Dr. Singha has supervised numerous research projects and has been instrumental in developing novel polymer systems with commercial potential. His work on inverse vulcanization, Diels-Alder chemistry, and self-healing materials has opened new avenues for sustainable polymer applications. The research group maintains strong collaborations with industry partners, particularly in the tire and coating sectors, translating fundamental research into practical technologies. His laboratory has developed expertise in various polymerization techniques including RAFT, ATRP, and ultrasonic-assisted methods, with applications ranging from biomedical materials to environmental remediation technologies. The research demonstrates a clear trajectory toward creating smarter, more sustainable polymer materials with enhanced functionality and environmental compatibility.