جستجوی استاد راهنمای دانشگاهی

Michael Lampson is Professor of Biology at the University of Pennsylvania's School of Arts and Sciences, with secondary appointments in the Department of Cell and Developmental Biology. He serves as faculty in the Cell and Molecular Biology (CAMB) and Biochemistry and Molecular Biophysics (BMB) Graduate Groups, and is affiliated with the American Society for Cell Biology (ASCB). Ph.D., Cornell University, Weill Medical College, 2002 AB, Harvard College, 1994 Dr. Lampson's research program focuses on fundamental mechanisms of chromosome biology, with particular emphasis on cell division, centromere inheritance, and meiotic drive. His lab investigates how selfish genetic elements can violate Mendel's First Law through meiotic drive, the stability of centromere chromatin through the germline, and the role of repetitive satellite DNA in chromosome segregation. Using innovative approaches including mouse model systems, optogenetic tools, and biochemical techniques, his work bridges cell biology, genetics, and evolutionary biology to address questions with implications for reproductive biology, cancer, and genetic inheritance. Analysis of Dr. Lampson's recent publications reveals a strong focus on the intersection of centromere biology, meiotic drive, and chromosome segregation mechanisms. His work increasingly incorporates computational approaches alongside experimental systems to study evolutionary aspects of centromere function. The research demonstrates consistent innovation in methodology, particularly in developing optogenetic tools for precise manipulation of cellular processes. Key themes include the role of satellite DNA variation, mechanisms of non-Mendelian inheritance, and the stability of chromatin structures through cell division and development. Searle Scholar Award American Association for the Advancement of Science (AAAS) fellow Dr. Lampson's research is supported by multiple NIH grants including from NIGMS, NHGRI, NICHD, and NCI, as well as University of Pennsylvania funding sources including the University Research Foundation, Abramson Cancer Center, and several specialized research centers. He collaborates extensively with researchers across disciplines, including Ben Black (Biochemistry), Dennis Discher (Chemical Engineering), Dave Chenoweth (Chemistry), and Roger Greenberg (Cancer Biology), reflecting the interdisciplinary nature of his work. His lab has trained numerous graduate students and postdocs who have gone on to successful careers in academia and industry. The Lampson Lab maintains state-of-the-art facilities for cell biological, genetic, and biochemical research, with specialized equipment for live-cell imaging, optogenetic manipulation, and mouse genetics. The lab fosters a collaborative environment that bridges molecular, cellular, and evolutionary perspectives on chromosome biology.

• Cell and Developmental Biology
• Evolution
• Cell biology of meiotic drive
• +۷ مورد دیگر

Kara McKinley is an Assistant Professor of Stem Cell and Regenerative Biology at Harvard University , joining the department in 2021. She is a Principal Faculty member at the Harvard Stem Cell Institute , an Associate member of the Broad Institute of MIT and Harvard , and a Freeman Hrabowski Scholar at the Howard Hughes Medical Institute . Her research focuses on the regenerative capacity of the human uterus , particularly the endometrium, which undergoes ~400 cycles of tissue remodeling, shedding, and repair during the reproductive lifespan. Using rodent models , genetic, molecular, and live microscopy tools, her lab investigates cellular and molecular mechanisms of regeneration, defects leading to diseases like endometriosis, and applications in regenerative medicine . Her work also explores cell division , centromere biology , and CRISPR genome engineering . Current research trends in her publications include epithelial zonation in the small intestine , mechanisms of endometrial regeneration , macropinocytosis in Hydra , and academic mentorship strategies . Her studies span cellular biomechanics , mitotic regulation , and translational approaches for tissue repair. NIH Director’s New Innovator Award (terminated in 2025 litigation with federal government) Freeman Hrabowski Scholar (Broad Institute) Kara mentors Harvard undergraduates, graduate students, and postdoctoral fellows through rotations and research opportunities. Her lab is based at Harvard’s Bauer 306 and advocates for gender equity in life sciences faculty via the Leading Edge initiative. Funding includes a now-terminated NIH New Innovator grant aimed at menstrual health research.

• Regenerative Medicine
• Reproductive Biology
• Cell Biology
• +۹ مورد دیگر

Chenshu Liu is an Assistant Professor in the Department of Biological Sciences at Lehigh University, where he launched his independent laboratory in fall 2024. His research focuses on meiotic quality control mechanisms, specifically investigating nuclear envelope dynamics during oocyte development using Caenorhabditis elegans as a model organism. Dr. Liu's educational background includes: BS in Biological Sciences from the University of Science and Technology of China PhD in Cell Biology from Columbia University Postdoctoral training as a Life Sciences Research Foundation Fellow at UC Berkeley His research integrates Cell Biology , Genetics , and Mechanotransduction to address fundamental questions in Meiosis and Gamete Development . The lab employs high-resolution live imaging, synthetic biology, and genetic approaches to study how nuclear envelope mechanics detect chromosomal errors and eliminate defective gametes—a process critical for preventing infertility and congenital disorders like Down syndrome. Publication trends reveal a clear evolution from early work on centromere dynamics (2015-2018) to current breakthroughs in nuclear envelope mechanobiology (2023-2024). Recent Science and Science Advances papers establish Piezo channels as central to meiotic quality control, highlighting conserved mechanisms between nematodes and mammals. Key recognition includes: Life Sciences Research Foundation Postdoctoral Fellowship Dr. Liu actively recruits graduate students for his Lehigh-based lab, emphasizing rigorous science within a supportive environment. He serves on the Graduate Recruitment and Fellowship Committee and teaches advanced courses including BIOS397/431 (Meiosis4Eva) and BIOS421 (Molecular Cell Biology I). The lab's NIH-relevant work bridges basic cell biology with clinical reproductive health challenges. The Liu Lab (theliulab.org), housed in Iacocca Hall, operates as a collaborative hub within Lehigh's #Meiosis4Eva community, utilizing C. elegans to pioneer discoveries in gamete quality control with implications for human fertility.

• Cell Biology
• Molecular Biology
• Genetics
• +۳ مورد دیگر

Laura Rusche is a Professor in the Department of Biological Sciences at the University at Buffalo. Her research focuses on chromatin structure, gene expression regulation, and evolutionary mechanisms in yeast. She investigates how sirtuins and heterochromatin proteins like Sir3 contribute to epigenetic control and respond to metabolic stress. Her work spans multiple yeast species to understand evolutionary adaptations in protein functions and transcriptional circuits. Education: BS from Yale University (Molecular Biophysics & Biochemistry), PhD from Johns Hopkins University (Biochemistry), and postdoctoral training at UC Berkeley. Research Interests: Chromatin dynamics, sirtuin-mediated epigenetic regulation, gene duplication consequences, and fungal pathogen biology. Key projects include studying Sir2's role in NAD+ stress responses and the evolution of Sir3 from replication proteins. Lab: The Rusche Lab explores centromere stability, heterochromatin formation in Candida species, and evolutionary genomics. Recent work highlights unique centromere structures in Candida auris and the functional divergence of sirtuins across yeasts.

• Chromatin Biology
• Gene Expression Regulation
• Evolutionary Genomics
• +۳ مورد دیگر

Iain Cheeseman is a Professor of Biology at the Massachusetts Institute of Technology and a Member of the Whitehead Institute, where he holds the Margaret and Herman Sokol Chair in Biomedical Research. He became a Member of Whitehead Institute and assistant professor at MIT in 2007, was promoted to full professor in 2018, and became the Herman and Margaret Sokol Professor of Whitehead in 2020. Since 2022, he has served as associate department head for MIT Biology. Dr. Cheeseman completed his undergraduate training at Duke University and earned his doctorate in molecular and cell biology in 2002 from the University of California, Berkeley, working in the labs of David Drubin and Georjana Barnes. He conducted postdoctoral research at the Ludwig Institute for Cancer Research in San Diego and UC San Diego under Arshad Desai. The Cheeseman Lab focuses on understanding the molecular machinery involved in chromosome segregation and cell division, with particular emphasis on the kinetochore—a complex structure of over 100 proteins that connects chromosomes to the cellular machinery powering their movement. His research has transformed how scientists view the kinetochore as a molecular machine. Current work explores how cellular processes and their molecular machinery are rewired across different contexts including between cell types, during development, depending on cell state, in disease, and across evolution. Analysis of his recent publications reveals a consistent focus on mitotic regulation, protein variants, and kinetochore function. His work has increasingly examined translational isoforms, alternative splicing, and the precise regulatory mechanisms controlling protein production during cell division. This research has implications for understanding fundamental biological processes and potentially improving cancer therapies. Fellow of the American Society for Cell Biology (2023) MIT Undergraduate Research Opportunities Program Outstanding Mentor - Faculty (2019) Keith R. Porter Fellow (2013) American Society for Cell Biology Early Career Life Scientist Award (2012) R.R. Bensley Award for Cell Biology from the American Association of Anatomists (2011) Human Frontiers Science Program Young Investigator Award (2010-2013) Searle Scholar Award (2009-2012) New Investigator Grant, Massachusetts Life Sciences Center (2008-2011) Smith Family Award for Excellence in Biomedical Research (2007) Dr. Cheeseman is deeply committed to mentoring the next generation of scientists and increasing diversity in science. He serves on the ASCB's Women in Cell Biology Committee and is a Board Member and Treasurer for ASAPbio, a non-profit promoting innovations in life science communication. His lab employs diverse experimental approaches including cultured human cells and large-scale cell biological studies using optical pooled screening to analyze single-cell traits across millions of cells.

• Cell Biology
• Chromosome Segregation
• Cell Division
• +۵ مورد دیگر

Scott Gitlin serves as Assistant Dean of the Medical Education Continuum at Michigan Medicine, University of Michigan. He holds a faculty position in the Department of Internal Medicine within the Medical School, with a focus on hematology/oncology education and medical curriculum development. Dr. Gitlin's research interests center on medical education, particularly competency-based medical education (CBME) in internal medicine clerkships. His work examines educational frameworks, assessment methodologies, and the development of entrustable professional activities (EPAs) for medical students. Additionally, he has substantial expertise in hematology/oncology education, with a specific focus on addressing the shortage of specialists in non-malignant hematology. Medical Education Curriculum Development Competency-Based Assessment Systems Internal Medicine Clerkship Design Hematology/Oncology Education Non-Malignant Hematology Workforce Issues Research Mentorship Training His publication record reveals a strong emphasis on medical education innovation, with significant contributions to competency-based frameworks for internal medicine clerkships and research on hematology-oncology career pathways. His work addresses critical challenges in medical education, including the declining interest in non-malignant hematology specialties and effective assessment methodologies for medical knowledge. Dr. Gitlin has been instrumental in developing faculty development initiatives, notably through the American Society of Hematology (ASH) Medical Educators Institute, which provides curriculum development skills and professional growth opportunities for hematology educators. Principal investigator on medical education research projects Co-developer of competency-based assessment frameworks for internal medicine clerkships Contributor to ASH Medical Educators Institute Researcher studying hematology-oncology career pathways His work spans both educational scholarship and clinical research, with publications in hematology/oncology addressing conditions like haemophagocytic lymphohistiocytosis and multiple myeloma, demonstrating his dual commitment to medical education and clinical hematology.

• Medical Education
• Competency-Based Medical Education
• Hematology/Oncology
• +۴ مورد دیگر

Duncan J Clarke is a Professor in the Department of Genetics, Cell Biology and Development at the University of Minnesota Medical School. His research focuses on the molecular mechanisms of chromosome segregation during cell division, with particular emphasis on the role of DNA topoisomerases and related proteins. Dr. Clarke's research interests include: Mechanisms of chromosome segregation during mitosis Function of DNA topoisomerase II in centromere and kinetochore regulation Role of SUMOylation in chromosome dynamics Spindle assembly checkpoint mechanisms Interactions between histone modifications and chromosome segregation machinery Connections between DNA topology and cell division His recent publications reveal a strong focus on the molecular details of chromosome segregation, particularly examining how DNA topoisomerases, histone modifications, and microtubule dynamics coordinate to ensure accurate chromosome distribution during cell division. His work bridges basic molecular mechanisms with potential clinical applications in cancer therapy, as evidenced by his research on topoisomerase inhibitors. Dr. Clarke has received significant research funding from NIH, including: Control of Chromosome Segregation by DNA Topoisomerase II (2024-2028) A high-throughput screen for inhibitors of Plk1-interacting checkpoint helicase (PICH) (2022-2025) Multiple previous NIH-funded projects dating back to 2003 His laboratory utilizes both yeast and mammalian model systems to investigate fundamental mechanisms of chromosome segregation that are conserved across species, with potential implications for understanding cancer development and improving cancer therapies.

• Chromosome Segregation
• DNA Topoisomerase
• Mitosis
• +۷ مورد دیگر

Barbara Mellone is a Professor in the Department of Molecular and Cell Biology / Genetics and Genomics at the University of Connecticut. She leads the Mellone Lab, which focuses on understanding how genetic information is accurately passed from one cell generation to the next through the study of centromeres. Her research interests include: Centromere biology and function Chromosome segregation mechanisms Genetic and epigenetic regulation of centromeres Evolution of centromeres across species Using Drosophila melanogaster as a model system for chromosome studies Connections between chromosome segregation errors and human diseases like cancer Professor Mellone's recent publications demonstrate a strong focus on centromere structure and function, particularly examining CENP-A chromatin, centromere assembly factors like CAL1, and the evolutionary aspects of centromere biology. Her work combines genetic, molecular, and evolutionary approaches to unravel the fundamental mechanisms of chromosome inheritance. Her laboratory has made significant contributions to understanding how centromeres are built, maintained, and evolve, with implications for human diseases associated with chromosome segregation errors.

• Centromere Biology
• Chromosome Segregation
• Genetics
• +۴ مورد دیگر

Rachel O'Neill serves as a Board of Trustees Distinguished Professor in the Department of Molecular and Cell Biology at the University of Connecticut's College of Liberal Arts and Sciences. Her research bridges molecular genetics, cytogenetics, and computational genomics to investigate fundamental mechanisms of genome stability and evolution across diverse eukaryotic species. Her primary research interests focus on retroelement transcription, centromere function, chromosome evolution, and species-specific genomic adaptations. O'Neill's lab pioneers telomere-to-telomere (T2T) genome assembly methodologies using next-generation sequencing technologies, establishing non-traditional model organisms including marsupials, monotremes, birds, marine species, plants, and insects for comparative genome biology studies. Human Telomere-to-Telomere Consortium Primate T2T Consortium Gibbon T2T Consortium Earth Biogenomes Project Ruminant T2T Consortium Fly T2T Consortium Deep Ocean Genomes Project Antarctic Genomes Consortium Colossal Foundation UConn’s Biodiversity and Conservation Genomics program O'Neill's recent publications (2021-2025) demonstrate leadership in large-scale genomics initiatives, with significant contributions to understanding centromere biology, sex chromosome evolution, and conservation genomics. Her work spans marsupial mole genomics, ruminant chromosome evolution, and epigenetic regulation of X-chromosome inactivation, reflecting her lab's broad impact across evolutionary biology, conservation, and fundamental genome science. Her laboratory actively trains students through cohort-based programs including the RaMP Cohort and Biodiversity and Conservation Genomics Program, securing substantial collaborative funding through multi-institutional consortia. The lab maintains strong infrastructure for advanced genome assembly and epigenomic analysis, with particular expertise in challenging repetitive regions and non-model organism genomics.

• Genome Stability
• Retroelement Transcription
• Centromere Function
• +۵ مورد دیگر

Maria M. Viveiros is an Associate Professor and Assistant Department Head in the Department of Physiology and Pharmacology at the University of Georgia’s College of Veterinary Medicine. Her research integrates experimental approaches like live cell imaging, molecular biology, and genetic mouse models to study meiotic division accuracy in oocytes, genomic stability, and the effects of environmental toxicants on embryonic development. She co-leads the Dr. Viveiros’s Lab and participates in interdisciplinary programs such as the Interdisciplinary Toxicology and Regenerative Biosciences Programs. Dr. Viveiros holds a PhD in Physiology and Pharmacology from the University of Guelph (Canada), an MSc from the same institution, and a BSc from McMaster University (Canada). She coordinates multiple graduate courses, including Integrative Systems Physiology I and II (VPHY 8210 and VPHY 8250), and leads the Endocrine and Reproductive Systems I course (VETM 5194). Her research interests focus on cell and developmental biology, regenerative medicine, reproductive physiology, and toxicology. Key projects address mechanisms regulating meiotic spindle assembly, monitoring chromosome attachment, and assessing how aging and environmental factors disrupt these processes. She explores epigenetic control of oocyte maturation, centromere function, and the impact of chemicals like bisphenol on gamete and embryo health. Publications highlight her work on pericentric satellite transcription, bisphenol toxicity, and epigenetic modifiers in oogenesis. Her contributions bridge molecular and cellular mechanisms with broader implications for human health, such as Down Syndrome and pregnancy loss linked to meiotic errors. She also investigates the role of proteins like ATRX, NEDD1, and Aurora Kinase A in spindle stability and chromosome segregation.

• Cell and Developmental Biology
• Regenerative Medicine
• Reproductive Physiology
• +۳ مورد دیگر

Arunika Das is an Assistant Professor in the Department of Biomedical Sciences at the Cornell University College of Veterinary Medicine , where she leads the Das Lab. Her research focuses on the genetic and epigenetic mechanisms governing chromosome inheritance during meiosis and early development, with a particular emphasis on centromere biology and aneuploidy. Education: PhD in Cell and Developmental Biology (Rutgers University, 2016), MS in Biochemistry (University of Calcutta, 2009), BS in Chemistry (St. Xavier’s University, 2007) Research Highlights: Investigates centromere inheritance through reproductive and embryonic challenges Studies aneuploidy mechanisms in early embryos Uses mouse, fly, and horse models for comparative genome stability analysis Active in Cornell Center for Reproductive Sciences and Center for Vertebrate Genomics Scientific Awards: Society for the Study of Reproduction - Emerging Investigator Award (2024-2025) S. Walter Englander Postdoctoral Research Award (2022) Keith R. Porter Award Honorable Mention (2022) Marine Biological Laboratory Fellowship (2017) Teaching: Leads curriculum development for a reproductive medicine MS program and teaches in Cornell’s Veterinary School. Mentors graduate, undergraduate, and capstone projects.

• Epigenetics
• Chromatin Biology
• Reproductive Aging
• +۵ مورد دیگر

Rahul Siddharthan is a computational biologist at The Institute of Mathematical Sciences (IMSc), Chennai , with research interests spanning bioinformatics algorithms, regulatory genomics, chromatin structure, evolutionary biology, and machine learning applications in clinical outcomes. He holds a PhD in Physics from the Indian Institute of Science, Bangalore, and transitioned to biology during a postdoc at the Rockefeller University, New York. At IMSc, he has led the Computational Biology group since 2013 and contributed to a new PhD program in this field. PhD: Physics, Indian Institute of Science, Bangalore Postdoc: Rockefeller University, New York Current Affiliation: IMSc, Chennai Leadership: Computational Biology group (since 2013) Research Interests include: Bioinformatics Algorithms Regulatory Genomics Chromatin Structure Evolutionary Biology Machine Learning in Clinical Data His recent publications focus on machine learning for fetal growth prediction , clustering methods for clinical data , and evolutionary analysis of fungal pathogens . He actively supervises PhD students and collaborates with medical institutions like Apollo Hospitals and Warwick Medical School. Rahul also organizes interdisciplinary workshops such as 'Machine Learning for Health and Disease' at ICTS Bengaluru and 'Aspects of Gene and Cellular Regulation' at IMSc. Advising and Collaborations involve mentoring current PhD students Sankarsan Dutta and Akash Sivaraman, with past advisees including Pavitra S (defended 2025), Chandrani Kumari (submitted 2024), and Rakesh Netha Vadnala (PhD 2023). Key collaborators include Dr. Uma Ram (Seethapathy Clinic), Leelavati Narlikar (IISER Pune), and Ponnusamy Saravanan (Warwick). Technical Contributions include developing algorithms like THiCweed for ChIP-seq motif discovery and ClaID for Candida auris clade identification. His group engages in projects related to chromatin organization , transcription factor interactions , and genomic data analysis .

• Bioinformatics
• Regulatory Genomics
• Chromatin Structure
• +۶ مورد دیگر

Richard Katz, PhD, is a Professor and Adjunct Professor at the Fels Institute for Cancer Research and Molecular Biology, Temple University School of Medicine, based at Fox Chase Cancer Center. His research focuses on epigenetic regulation in cancer, particularly the role of the nuclear lamina in organizing heterochromatin and gene silencing. PhD in Microbiology, Columbia University (1983) BS in Biology, Summa cum laude, Syracuse University (1975) Dr. Katz's research spans several key areas in epigenetics and cancer biology. He investigates how the nuclear lamina controls epigenetic silencing through proteins like PRR14, which tethers heterochromatin to the nuclear periphery. His lab uses siRNA-based genome-wide screens to identify novel epigenetic silencing networks. Another major focus is melanoma plasticity, where his team discovered ID4 as a key mediator. He also studies epigenetic antiviral responses involving Daxx and retroviral silencing, and functional analysis of breast cancer genes from GWAS and DASE studies using BioID for protein interaction mapping. His recent publications reveal a strong trend in understanding chromatin dynamics, epigenetic silencing mechanisms, and their implications in cancer and viral defense. His work integrates molecular biology, functional genomics, and systems approaches to dissect complex regulatory networks. Notable scientific recognitions include being selected for Cover Art in Epigenetics (2014) and an Article of Significant Interest by the editors of Journal of Virology (2013). Dr. Katz actively mentors students and technicians in his lab, including graduate students and post-baccalaureate researchers. He collaborates widely across Fox Chase, including with J.P. Issa, A. Bellacosa, and A.M. Skalka. His lab participates in the Undergraduate Summer Research Fellowship and research volunteering programs, indicating a strong commitment to training and education. His lab at Fox Chase (R422/W422) includes current members such as Valentina Medvedeva (Graduate Student), Trinity Pellegrin (Scientific Technician), and several student assistants, reflecting an active and collaborative research environment.

• Epigenetic Regulation
• Cancer Epigenetics
• Nuclear Lamina
• +۷ مورد دیگر

David M. Markovitz is a tenured Professor in the Department of Internal Medicine at the University of Michigan Medical School. He has maintained continuous faculty appointments at the University since 1988, progressing from Assistant Professor (1988-1994) to Associate Professor with tenure (1994-2002) and ultimately to his current Professor position (2002-present). Dr. Markovitz leads a multidisciplinary research team comprising four additional faculty members, postdoctoral fellows, PhD students, MD/PhD students, medical students, physicians, public health students, and undergraduates. Dr. Markovitz's research program spans several interconnected domains in molecular medicine. His laboratory employs diverse methodologies including NMR, crystallography, molecular dynamics modeling, glycoclusters, next-generation sequencing, bioinformatics, and animal models to investigate viral pathogenesis and develop novel therapeutic approaches. His work has produced 92 publications and resulted in significant discoveries across multiple fields. The publication record reveals several major research trajectories: investigations into HIV transcription mechanisms; characterization of the DEK protein's role in cancer and juvenile arthritis; discovery of vimentin as a secreted inflammatory factor; exploration of human endogenous retroviruses (HERVs) in disease pathogenesis; and development of engineered lectins as broad-spectrum antiviral agents. His most notable contribution involves engineering banana lectin (BanLec) through a single amino acid mutation (H84T) that eliminates mitogenicity while preserving antiviral activity against HIV, hepatitis C, influenza, and coronaviruses including SARS and MERS. Dr. Markovitz has received numerous prestigious awards including the Burroughs Wellcome Clinical Scientist Award (2003), Association of American Physicians membership (2004), and a Transformative R01 from the NIH Office of the Director (2009). National Cancer Institute – Clinical Investigator Award (1990) Life and Health Insurance Medical Research Fund Scholar (1991) American Society for Clinical Investigation (1997) Burroughs Wellcome Clinical Scientist Award (2003) Association of American Physicians (2004) Transformative R01, NIH (2009) American Clinical and Climatological Association (2012) His current research portfolio demonstrates strong funding support across multiple domains. As Principal Investigator, he leads projects including DEK-targeted therapy for juvenile arthritis (Rheumatology Research Foundation), development of H84T BanLec for Ebola/Marburg treatment (DTRA), and lectin-based lung cancer therapy (UM Mi-Kickstart). As Co-PI, he contributes to NIH-funded research on DEK in hematopoiesis and international collaborations studying HERVs in human disease. His mentorship extends to numerous doctoral students, postdocs, and medical trainees who have gone on to independent research careers. Dr. Markovitz directs a vibrant research ecosystem that includes faculty collaborators Rafael Contreras, Scott Gitlin, and Mark Kaplan. His laboratory maintains extensive collaborations across the University of Michigan and with international partners. The research program bridges basic science discoveries with translational applications, particularly in developing novel therapeutics for viral diseases, autoimmune conditions, and cancer. His work on DEK aptamers and engineered lectins represents promising pathways toward clinical applications in inflammation and infectious disease.

• Molecular Immunology
• Virology
• Cell Biology
• +۳ مورد دیگر

Gregory C. Rogers is a Professor in the Department of Cellular and Molecular Medicine at the University of Arizona, with additional appointments in the BIO5 Institute, Cancer Biology GIDP, and Genetics GIDP. He specializes in molecular mechanisms governing centriole duplication and centrosome instability in cancer progression. Education: BA in Biology from the University of Rochester PhD in Cell and Developmental Biology from University of California, Davis Postdoctoral training at Albert Einstein College of Medicine and University of North Carolina, Chapel Hill His research focuses on centriole duplication control, centrosome amplification/loss in prostate cancer, and the role of Polo-like kinase 4 (Plk4) in mitotic errors. Articles from 2010-2025 highlight his work on centrosome dynamics, cancer-related chromosomal instability, and Drosophila model applications. Recent studies (2023-2025) explore PIM kinase inhibition in immunotherapy, Plk4 regulation, and centrosome loss as a driver of prostate malignancy. Earlier work (2010-2019) established foundational knowledge of centriole assembly and condensin II function.

• Centriole Duplication
• Centrosome Instability
• Chromosomal Instability (CIN)
• +۶ مورد دیگر