جست‌وجوی استاد و پژوهشگر

• Cellular and Molecular Neuroscience
• Retinal Development
• Neural Stem Cell Biology
• +۶ مورد دیگر

Michel Cayouette is a full Professor at the Department of Medicine, Faculty of Medicine, University of Montreal. He is also the Director of the Vision Health Research Network (RRSV) and a member of the Institut de recherches cliniques de Montréal (IRCM). His research focuses on cellular and molecular mechanisms regulating retinal neurogenesis, neural stem cell therapies, and neurodegenerative disease pathways. Director, Vision Health Research Network (RRSV) Member, IRCM Professor, Department of Medicine, University of Montreal Dr. Cayouette's work explores temporal identity factors in retinal progenitors, Hedgehog signaling regulation, and endocytic trafficking mechanisms. His team uses genetic approaches in mice and live-cell imaging to develop stem cell-based therapies for retinal dystrophies and central nervous system reconstruction. Recent publications highlight his contributions to understanding retinal development (2023-2025), including temporal identity regulation, Hedgehog pathway interactions, and endocytic trafficking in retinal patterning. Key grant funders include Canadian Institutes of Health Research (CIHR), Fonds de recherche du Québec - Santé (FRQS), and the Foundation Fighting Blindness. He has supervised doctoral and master's students in projects examining: Myocyte complexity in embryonic myogenesis (2025) Transcriptional regulation in retinal progenitor cells (2021) Photoreceptor polarity and ciliogenesis (2020) Mitotic spindle regulation in retinal development (2017) Current research initiatives include: Stem cell therapies for retinal dystrophies (2018-2027) Multisensory integration mapping in awake mice (2024) Clinical assessment of MOBIVIS concussion management (2023)

• Immunology
• Transplantation
• Graft Rejection
• +۵ مورد دیگر

Jean-François Cailhier is an Associate Professor in the Department of Medicine at the University of Montreal's Faculty of Medicine. He is also a member of the CRCHUM (Centre de recherche du Centre hospitalier de l'Université de Montréal), where he conducts research in immunology and transplantation. Dr. Cailhier's research focuses on several key areas in immunology and transplantation medicine: Macrophage biology and reprogramming in transplantation Immunomodulation and inflammation in organ transplantation Cellular immune responses in graft rejection Role of senescence in inflammatory processes MFG-E8 signaling pathways in kidney repair and fibrosis Transcriptomic expression patterns in stem cell therapies His research spans multiple clinical contexts including organ transplantation, critical care, and viral infections. Dr. Cailhier's work often involves interdisciplinary collaborations with researchers in immunology, nephrology, and biomedical engineering. His laboratory investigates how tissue microenvironments influence immune cell behavior, with particular emphasis on macrophage reprogramming and inflammatory responses. Dr. Cailhier has supervised eight graduate students between 2014 and 2022, including two PhD candidates and six Master's students. His research has been supported by numerous funding agencies including the Canadian Institutes of Health Research (CIHR), the Fonds de recherche du Québec - Santé (FRQS), and various foundations. Current projects include investigating inflammatory phenotypes in HIV, developing adoptive immunotherapy against BK polyomavirus, and using ultrasound technology to promote anti-inflammatory macrophage responses.

Jeffrey Biernaskieمشاهده پروفایل

استاد

• Stem Cells
• Tissue Regeneration
• Wound Healing
• +۳ مورد دیگر

Dr. Jeffrey Biernaskie is a Full Professor at the University of Calgary's Faculty of Veterinary Medicine, where he holds the Calgary Firefighters Burn Treatment Society Chair in Skin Regeneration and Wound Healing. He serves as Director of the Centre for Cell Therapy Translation and Chair of the Reproduction and Regenerative Medicine Research Group. His affiliations include the Hotchkiss Brain Institute and Alberta Children's Hospital Research Institute. Education: BSc in Neuro Psychology (University of Lethbridge, 1998) PhD in Neuroscience (Memorial University, 2004) Postdoctoral Fellowship in Skin and neural stem cell biology (The Hospital for Sick Children, 2009) Research Focus: Dr. Biernaskie investigates cellular and molecular mechanisms governing fibrotic versus regenerative healing, aiming to restore organ function post-injury. His lab studies how skin/brain stem cells are regulated during homeostasis and how injury, aging, and immunity impact their function. Key areas include stem cell reprogramming, immune modulation of regeneration, and single-cell analysis of tissue repair. Publication Trends: His recent work emphasizes regenerative medicine innovations, particularly in skin/brain repair, using advanced techniques like spatial transcriptomics and single-cell genomics. Themes include stem cell plasticity, immune-microenvironment interactions, biomaterial applications, and translational models of wound healing. Awards & Honors: Killam Professor (2024) Royal Society of Canada College Scholar (2019) CIHR New Investigator Award (2011) Multiple postdoctoral fellowships and early-career recognitions Leadership: Dr. Biernaskie directs the Biernaskie Lab, an interdisciplinary team exploring stem cell biology and tissue regeneration. The lab collaborates across neuroscience, immunology, and bioengineering to develop therapies for burns, nerve injuries, and degenerative conditions.

Vaibhav Patelمشاهده پروفایل

دانشیار

• Cardiovascular Disease
• Intercellular Communication
• Exosome Biology
• +۴ مورد دیگر

Dr. Vaibhav Patel is an Associate Professor in the Department of Physiology and Pharmacology at the Cumming School of Medicine, University of Calgary, and a researcher at the Libin Cardiovascular Institute. His work focuses on intercellular communication mechanisms in cardiovascular disease, particularly the role of perivascular adipocyte-secreted exosomes and mitochondrial dynamics in vascular pathology. B.Pharm, M.Pharm, and Ph.D. in Pharmacology from Maharaja Sayajirao University of Baroda (2005-2011) Postdoctoral fellowship at University of Alberta's Department of Medicine Dr. Patel's research explores how extracellular vesicles modulate renin-angiotensin system components in vascular smooth muscle and endothelial cells to influence disease progression. His work bridges molecular signaling in diabetes-related cardiovascular complications with therapeutic strategies targeting ACE2/Ang 1-7 axis and mitochondrial homeostasis. His publications analyze: Mitochondrial dynamics in vascular cell death Exosomal miRNA regulation of cardiac fibrosis RAS component interactions in diabetic cardiomyopathy Pharmacological inhibition of Drp1 in aortic aneurysms Metabolic switching in vascular smooth muscle and fibroblasts Scientific awards include: Todd Anderson Cardiovascular Research Award (2023) New Investigator Award, Heart and Stroke Foundation (2022) Young Investigator Award, Canadian Cardiovascular Society (2022) CCS/HSRLCE/BI-Lilly Cardiometabolic Research Award (2021) His academic career spans postdoctoral research on ACE2 therapeutic potential, national fellowships, and extensive publications (60+ peer-reviewed articles). He investigates cytoskeletal remodeling in heart failure and develops exosome-based interventions for myocardial repair.

• Epigenetic pharmacology
• Cancer research
• Drug discovery
• +۶ مورد دیگر

Noël JM Raynal is an Associate Professor in the Department of Pharmacology and Physiology at the University of Montreal's Faculty of Medicine and a Principal Investigator at the Azrieli Research Center at CHU Sainte-Justine. He serves as Director of the Chemical Molecule Screening Platform at the research center. Dr. Raynal leads a research laboratory focused on epigenetic pharmacology of cancer and drug discovery through molecular screening systems. Dr. Raynal's research expertise lies in developing 3D cell culture models that better reproduce cancers in the laboratory, which his team characterizes at epigenetic and pharmacological levels. His laboratory focuses on both pediatric cancers (including leukemia, neuroblastoma, and sarcomas) and adult cancers (such as lung cancer and triple-negative breast cancer). His work combines epigenetic drugs targeting DNA methylation and histone modifications with other therapeutic approaches to identify synergistic anticancer interactions. Analysis of Dr. Raynal's recent publications reveals a strong focus on drug repurposing strategies, particularly applying existing medications to new cancer indications. His research demonstrates expertise in epigenetic mechanisms including DNA methylation, histone acetylation, and CDK9 inhibition, with applications across multiple cancer types. A notable trend is his laboratory's work on translating basic epigenetic discoveries into potential therapeutic applications, particularly for difficult-to-treat pediatric malignancies. Scientific Awards: Bourse de chercheur-boursier Senior du FRQS (2024-2028) Bourse de chercheur-boursier Junior 2 du FRQS (2020-2024) Bourse IRICOR-ONCOPOLE pour l'Entreprenariat en Sciences de la Vie (2020-2021) Bourse de chercheur-boursier Junior 1 du FRQS (2016-2020) CIHR-New Principal Investigator Award (2015) Bourse de transition, Fondation Cole (2013-2016) Dr. Raynal has successfully mentored numerous graduate students and postdoctoral fellows who have contributed to his research program. His laboratory has secured substantial grant funding from multiple sources including FRQS and CIHR, supporting innovative research in epigenetic pharmacology. Dr. Raynal collaborates extensively with clinicians and researchers at CHU Sainte-Justine and other institutions to translate basic discoveries into potential therapeutic applications. His laboratory at the Azrieli Research Center at CHU Sainte-Justine includes master's students, postdoctoral fellows, and research assistants working together on various aspects of cancer epigenetics and drug discovery. The team utilizes advanced molecular screening systems and 3D cell culture models to investigate cancer biology and identify promising therapeutic approaches.

• Immunology
• Allergy and Asthma Research
• Dendritic Cell Biology
• +۳ مورد دیگر

Dr. John Gordon is a Professor at the College of Medicine , University of Saskatchewan , specializing in translational immunology . His research focuses on harnessing dendritic cells to suppress hyper-sensitive immune responses, with breakthrough applications in asthma , food allergies , and autoimmune diseases . He leads the Respiratory Research Centre, emphasizing collaborative strategies to advance immunotherapeutic solutions for respiratory conditions affecting millions of Canadians. Therapeutic Innovation: Reprogrammed dendritic cells reduce airway inflammation by 90% in preclinical models. Clinical Translation: Work extends to autoimmune diseases like Multiple Sclerosis via regulatory T cell mechanisms. Collaborative Vision: Advocates for resource-sharing through the Respiratory Research Centre to accelerate scientific breakthroughs. His publications span chemokine antagonism , dendritic cell therapy , and inflammatory disease models , with key contributions to allergy immunology and cancer treatment. Current efforts involve clinical trials for allergen-specific tolerance induction and interdisciplinary exploration of respiratory health challenges.