جست‌وجوی استاد و پژوهشگر

Stefanie Redemannمشاهده پروفایل

دانشیار

• Cell and Developmental Biology
• Molecular Biology
• Biophysics
• +۳ مورد دیگر

Stefanie Redemann is an Associate Professor at the University of Virginia , affiliated with the Department of Molecular Physiology and Biological Physics in the School of Medicine . She holds a Diploma in Biology from Technische Universität Darmstadt and a PhD in Cell Biology from the Max Planck Institute for Cell Biology and Genetics, with postdoctoral training at Technische Universität Dresden. Education: Diploma in Biology (Technische Universität Darmstadt), PhD in Cell Biology (Max Planck Institute), Postdoc in Cell Biology/Biophysics (Technische Universität Dresden) Her research focuses on chromosome segregation and aneuploidy in meiosis and mitosis , using advanced imaging techniques like 3D electron tomography and CRISPR tools in models such as tissue culture cells, mouse oocytes, and C. elegans embryos. She investigates molecular and mechanical principles of spindle assembly to address errors linked to cancer progression and reproductive health issues. Recent publications highlight work on microtubule dynamics, chromokinesin function, and tubulin regulation in meiosis. Awards include being named a Cell Scientist to Watch (2021). Her lab at the University of Virginia integrates interdisciplinary approaches to unravel mechanisms of cell division.

Niels Ørtenbladمشاهده پروفایل

استاد

• Muscle Physiology
• Cellular Biomechanics
• Metabolism
• +۵ مورد دیگر

Niels Ørtenblad , a Professor at the Department of Sports Science and Clinical Biomechanics, University of Southern Denmark, is a leading researcher in muscle physiology and biomechanics. His work focuses on the interplay between subcellular structures like glycogen, sarcoplasmic reticulum, and mitochondria in skeletal muscle function. Research Unit of Muscle Physiology and Biomechanics Scandinavian Journal of Medicine & Science in Sports collaborations Research Interests: Muscle metabolism, calcium ion regulation, glycogen storage, mitochondrial dynamics, and the impact of exercise on subcellular organelles. His studies explore how localized glycogen depletion affects sarcoplasmic reticulum calcium release, impairing muscle function during metabolic stress. Recent Article Trends: Investigations into high-altitude adaptation, endurance athlete lipid-mitochondria interactions, glycogen's role in cardiovascular diseases, and strength training effects on calcium handling. These works span disciplines like Exercise Biochemistry , Cellular Physiology , and Sports Performance Optimization . Teaching: He supervises courses such as 'Muscle Metabolism and E-C Coupling – Role in Exercise, Training and Disease' and contributes to 'Exercise as Medicine - Musculoskeletal Disorders'. Activities: Frequent lecturer on topics like 'Role of glycogen in skeletal muscle Ca²⁺ regulation' and 'Neuroprotective effects of aerobic exercise in multiple sclerosis,' with international collaborations.

• Cardiac Electrophysiology
• Cardiac Arrhythmias
• Lysosomal Calcium Signaling
• +۵ مورد دیگر

Associate Professor Rebecca Burton is a cardiac electrophysiologist in the Department of Pharmacology at the University of Oxford's Medical Sciences Division. Since completing her DPhil in 2006, she has led research on cardiac arrhythmias with focus on lysosomal calcium signaling and hydroxychloroquine's effects on heart rhythm. Her group of approximately 10 researchers employs novel imaging methods and traditional pharmacology techniques to study cardiac function. Her research interests center on cardiac arrhythmia mechanisms, particularly the role of lysosomal calcium stores in atrial fibrillation. She investigates cAMP-Ca 2+ cross talk in atrial nanodomains, IP3 receptor signaling , and acidic organelle function in cardiomyocytes. Her work bridges basic science with translational applications through collaborations with clinicians across disciplines. Her 15 most recent publications (2022-2025) demonstrate consistent focus on lysosomal calcium signaling in cardiac rhythm regulation, with particular emphasis on atrial-specific mechanisms. Key themes include compartmentalized cAMP signaling, NAADP-mediated calcium release, and the role of endolysosomal networks in atrial fibrillation pathophysiology. Scientific recognition includes: Winston Churchill Medal for contributions to Science and Technology (2015-2016) Sir Henry Dale Fellowship supporting her ambitious interdisciplinary research Beyond research, Burton serves in teaching roles including examination setting and marking, provides pastoral care at her college, and actively engages in public outreach through events like the Science Museum Lates. She has advocated for improved career pathways for early-career researchers and greater equality of opportunity in academia. Her laboratory specializes in advanced cardiac optical mapping, lysosomal calcium imaging, and multi-disciplinary approaches to studying the neuro-cardiac axis, with particular focus on how sympathetic neuronal activity affects cardiac conduction and arrhythmia susceptibility.

Jill Dowenمشاهده پروفایل

استاد

• Gene Regulation
• Chromosome Structure
• Genome Organization
• +۷ مورد دیگر

Jill Dowen is a Professor in the Department of Genetics at the University of North Carolina at Chapel Hill, focusing on the interplay between genome organization and gene expression. Her lab investigates how DNA looping influences cellular identity during development and disease, utilizing embryonic stem cells, cancer cells, and functional genomics approaches. Research interests include: Chromatin structure and transcriptional regulation 3D genome architecture in disease contexts Role of cohesin and Polycomb complexes in gene expression Histone modifications and their impact on chromatin dynamics Her recent publications highlight advancements in understanding cohesin's regulatory mechanisms, histone acetylation's role in MLL complex function, and Polycomb repressive complex interactions with lncRNA. The lab actively trains scientists and accepts applications for postdoctoral and graduate positions through the UNC BBSP PhD Program.

• Dynamical Systems
• Partial Differential Equations
• Pharmacology
• +۴ مورد دیگر

Vivi Rottschäfer is an Associate Professor in the Analysis and Dynamical Systems group at the Mathematical Institute, Leiden University , and holds a Professor position by special appointment in Industrial Mathematics at the Korteweg-de Vries Institute for Mathematics, University of Amsterdam. Her research focuses on Dynamical Systems , Partial Differential Equations , and their applications in Pharmacology , Health , and Ecology . She develops mathematical models for drug distribution in the brain, ecological pattern formation, and industrial problems, with a particular interest in blow-up phenomena , pattern dynamics , and multi-scale modeling . Recent publications (2025-2020) span cellular communication optimization , nanomaterial toxicokinetics , neural feedback dynamics , and ecosystem resilience . Her work often bridges pure mathematical analysis with real-world challenges, including collaborations in receptor theory , drug development , and environmental toxicology . She organizes major conferences like the International Congress on Industrial and Applied Mathematics (ICIAM 2027) and the Study Group Mathematics with Industry , and has taught advanced courses on Bifurcation Theory , Perturbation Methods , and Dynamical Systems since 2010.

• Neurobiology
• Cell Biology
• Biomedical Imaging
• +۳ مورد دیگر

Dr. Simone Mortal is a Postdoctoral Researcher at the Institute of Photonic Sciences (ICFO), part of the SLN - Team Loza research group. They hold a PhD in Neurobiology from the International School for Advanced Studies (Italy). Their work focuses on advanced imaging techniques and cellular neurobiology, with specialties in super-resolution imaging, multiphoton microscopy, and confocal microscopy. Research interests include mechanisms of glioblastoma replication, neuronal mechanotransduction, microtubule dynamics in neurodegenerative diseases, and cytoskeletal roles in neuronal development. Dr. Mortal's research bridges biophysics and neuroscience, addressing fundamental questions about cellular signaling and disease mechanisms. They are based in Barcelona, Spain, and can be reached at Simone.Mortal@icfo.eu. Education: PhD in Neurobiology (International School for Advanced Studies, Italy). Research Themes: Investigating calcium signaling in neurodegeneration, mechanosensitive pathways in neurons, and actin dynamics during neuronal maturation. Their studies employ cutting-edge microscopy techniques to visualize cellular processes at high resolution, with a focus on glioma-derived exosome effects, growth cone mechanics, and cytoskeletal scaffolding in neural development. Labs/Teams: Active member of the SLN - Team Loza group at ICFO, specializing in neurobiophotonics and cellular imaging.

Junzhong Xuمشاهده پروفایل

دانشیار

• Quantitative MRI Methods
• Neurodegenerative Diseases
• Cancer Imaging
• +۳ مورد دیگر

Junzhong Xu is an Associate Professor of Radiology and Radiological Sciences, Biomedical Engineering, and Physics and Astronomy at Vanderbilt University. His research focuses on developing advanced quantitative MRI methods for applications in neurodegenerative diseases and cancer, including MRI cell size imaging and tumor treatment response assessment. He holds affiliations with the Vanderbilt University Institute of Imaging Science (VUIIS) and has expertise in microstructural diffusion MRI and GPU-accelerated imaging tools. Xu’s work spans interdisciplinary collaborations in biomedical engineering and physics. Education: B.S., University of Science and Technology of China M.S., University of Science and Technology of China Ph.D., Vanderbilt University Research Interests: Development of MRI cell size imaging for cancer and neurodegenerative diseases Quantitative assessment of tumor microstructure and treatment response Applications of microstructural diffusion MRI in multiple sclerosis and oncology Key Contributions: Advancement of MRI cytometry for non-invasive disease assessment GPU-accelerated tools for diffusion MRI simulation (MATI) Imaging biomarkers for early detection of neurodegenerative pathology Labs/Teams: Active member of the Vanderbilt University Institute of Imaging Science (VUIIS), collaborating on interdisciplinary imaging projects.

William Y. C. Huangمشاهده پروفایل

استادیار

• Signal Transduction
• Cell Membrane Biochemistry
• Single-Molecule Imaging
• +۳ مورد دیگر

William Y. C. Huang is an Assistant Professor in the Department of Biophysics at Johns Hopkins University. He received his B.S. in Chemistry from National Taiwan University (2010) and Ph.D. in Chemistry from UC Berkeley (2016) under Dr. Jay Groves. After postdoctoral work at Stanford University (2018-2023) with Dr. James Ferrell, he launched his independent research program at Hopkins in 2024. Education: B.S. in Chemistry, National Taiwan University (2010) Ph.D. in Chemistry, University of California, Berkeley (2016) Research Focus: Quantitative study of biochemical reactions at cell membranes Signal transduction mechanisms Single-molecule imaging and spectroscopy Development of reconstituted membrane assays Investigation of protein condensation phase transitions Kinetic modeling of membrane-bound biochemical systems Scientific Awards: NIH Pathway to Independence Award Searle Scholar Contact: Email: whuang@jhu.edu Office: 168 Mergenthaler Hall Phone: (410) 516-0166

Marino Zerialمشاهده پروفایل

عضو هیئت علمی

• Molecular Cell Biology
• Membrane Biology
• Endocytosis
• +۳ مورد دیگر

Marino Zerial is a leading academic and researcher in molecular cell biology, serving as Director of the Max Planck Institute of Molecular Cell Biology and Genetics (MPI-CBG) and Honorary Professor at the Medical Faculty of Technische Universität Dresden. He obtained his biology degree from the University of Trieste (Italy) in 1982 and conducted postdoctoral research at the Institut Jacques Monod (Paris) and EMBL (Heidelberg). His work has focused on understanding endocytosis mechanisms, particularly the role of Rab GTPases in membrane fusion and organelle biogenesis. Zerial has pioneered translational research in liver disease, 3D tissue modeling, and drug delivery systems. He leads the Zerial Group, which integrates molecular biology, biophysics, and computational modeling to study cellular organization at multiple scales. Education: Biology (University of Trieste, 1982) Postdoctoral Training: Institut Jacques Monod, EMBL Affiliations: MPI-CBG (Director), TU Dresden (Honorary Professor) His research interests span endocytic pathways, liver tissue biophysics, and molecular motor mechanisms. Zerial has received prestigious awards, including the Gottfried Wilhelm Leibniz Prize (2006) and election to the American Academy of Arts and Sciences (2021). The Zerial Group collaborates on projects like LiSyM (liver cancer research) and ENDOSCAPE (gene delivery technology), emphasizing interdisciplinary approaches to biological challenges.

Noelia Landerمشاهده پروفایل

استادیار

• Molecular Parasitology
• Trypanosoma cruzi
• Chagas Disease
• +۹ مورد دیگر

Noelia Lander is an Assistant Professor at the University of Cincinnati's Department of Biological Sciences. Her research focuses on signal transduction pathways in Trypanosoma cruzi , the parasite responsible for Chagas disease. She pioneered CRISPR/Cas9 genome editing methods in this organism, enabling studies of calcium and cAMP signaling pathways critical for parasite survival and pathogenesis. Education: B.S. (Biology, Universidad Simón Bolívar, 2002), M.S. (Biological Sciences, Universidad Simón Bolívar, 2008), Ph.D. (Cellular Biology, University of Georgia, 2013). Postdoctoral training included roles at the University of Georgia and State University of Campinas. Current lab website: landerlab.uc.edu . Research interests include environmental sensing mechanisms, parasite differentiation, and drug target validation. Key contributions include identifying roles for calcium and cAMP signaling in T. cruzi 's life cycle transitions and host interactions. Recent work explores compartmentalized cAMP signals and mitochondrial Ca²⁺ regulation. Notable grants include NIH/NIAID funding for CRISPR screening of essential genes (R21AI140421, K99/R00AI137322) and a 2020 UGA Postdoctoral Research Award. Her lab's CRISPR tools have advanced studies of kinetoplastid parasites. Key achievements: Developed first CRISPR-based knockdown method for T. cruzi , discovered critical roles for mitochondrial calcium uniporter components, and identified CARP3 protein's role in cAMP signaling pathways.

Joseph L. Ransdellمشاهده پروفایل

استادیار

• Neuroscience
• Neurobiology
• Cellular Neuroscience
• +۳ مورد دیگر

Joseph L. Ransdell is an Assistant Professor at Miami University, affiliated with the Biology department, Cell, Molecular and Structural Biology Graduate Program, and the Center for Neuroscience and Behavior. His lab focuses on understanding how neuronal electrical activity supports brain function and contributes to neurological disorders. Research combines electrophysiology, molecular genetics, and computational methods to study Purkinje neuron excitability and its role in autism spectrum disorder. Education: Ph.D. from the University of Missouri. His research has led to over 9 peer-reviewed publications since 2010, with recent work emphasizing sodium channel regulation and motor coordination deficits. He teaches courses in Human Physiology and Cell Biology. Current projects investigate how mutations disrupting Purkinje neuron firing lead to behavioral disorders. The Ransdell Lab is located in Pearson Hall, emphasizing translational research bridging basic neuroscience and clinical applications.

• Cell Biology
• Molecular Biology
• Organelle Biology
• +۳ مورد دیگر

Inês Castro is an Assistant Professor in Biology and Associate Director for Global Experience within the CoMEMS faculty at Northeastern University London. She holds a PhD in Biosciences from the University of Exeter (2016), an MSc in Molecular and Cellular Biology from the University of Coimbra (2011), and a BSc in Applied Biology from the University of Minho (2009). Her research focuses on organelle function and interactions, particularly in peroxisomes and membrane contact sites across diverse model organisms. Her academic journey includes postdoctoral work at the Weizmann Institute of Science, where she studied contact site proteins in yeast using high-throughput techniques and microscopy. Key contributions include identifying molecular links between peroxisomes and kinesin motors, ER-peroxisome contact sites, and lipid transport mechanisms. She has established Biology courses for Mobility students and teaches General Biology I and II. Inês’ research spans cellular lipid distribution, organelle motility, and disease relevance of organelle dysfunction. Her work integrates in silico , in vivo , and microscopy approaches. Awards include the Fellowship of the Higher Education Academy (FHEA, 2023). Teaching and administrative roles include course leadership for General Biology I and contributions to other Biology courses. Her work supports Northeastern’s global academic network, emphasizing interdisciplinary collaboration and student mobility programs.

Philip Osdobyمشاهده پروفایل

استاد

• Bone Biology
• Cellular Immunology
• Regenerative Medicine
• +۳ مورد دیگر

Philip Osdoby is a Professor in the Department of Biology at Washington University. His research focuses on bone development, pathological bone loss, and regenerative medicine, particularly cell-based therapies and tissue engineering. He investigates cell-molecular interactions involving osteoclasts, osteoblasts, immune cells, and vascular cells, emphasizing endocrine and local signaling pathways. His work spans bone biology, cellular immunology, and molecular mechanisms underlying skeletal disorders. Key areas include osteoclastogenesis regulation, cytokine signaling (e.g., IL-1, TNF-α), chemokine receptor (CXCR4) roles in osteoclast recruitment, and biomineralization processes. He explores autocrine feedback mechanisms (e.g., iNOS/NO pathways) and the interplay between angiogenesis and bone resorption in vivo models like the chick chorioallantoic membrane. Publications highlight osteoclast formation from RAW 264.7 cells, galectin-3 isoforms, and SDF-1-driven osteoclast migration. His studies often integrate in vitro and in vivo approaches to dissect bone cell microenvironment dynamics. Philip Osdoby holds no explicitly listed scientific awards. His lab’s research has contributed to understanding osteoporosis, inflammatory bone diseases, and regenerative strategies for bone repair.

Shwetal Mehtaمشاهده پروفایل

استاد مدعو

• Cancer Biology
• Neuro-Oncology
• Molecular Biology
• +۳ مورد دیگر

Dr. Shwetal Mehta is an Adjunct Professor at Arizona State University (ASU), holding affiliations in the School of Life Sciences and School of Molecular Sciences. She is also part of the Ivy Brain Tumor Center. Her research focuses on molecular mechanisms driving glioma biology, particularly cancer stem cells and their roles in therapy resistance. She earned a Master’s in Molecular Biology from the Tata Institute of Fundamental Research, India, and holds a PhD (details not fully disclosed in text). Dr. Mehta teaches courses such as BIO 495 (Undergraduate Research) and NEU 591 (Seminar) across multiple semesters. Her lab investigates neurodevelopmental pathways hijacked by cancer stem cells, including epigenetic regulation (e.g., HDAC1), 3D tumor models, and glioma-vascular interactions. As Deputy Director and Pre-Clinical Core Leader at the Ivy Brain Tumor Center, she oversees preclinical trials for glioblastoma therapies. Her research has led to discoveries in Wnt signaling, glial signatures, and drug-response mechanisms in gliomas. Despite no awards explicitly listed, her work bridges basic science and clinical translation. Lab members include postdoctoral fellows (e.g., Sonam Patel, Gozde Uzunalli) and research technicians. Current projects explore genetic/epigenetic deregulations in cancer stem cells and vulnerabilities for novel therapies.

Jennifer Gunterمشاهده پروفایل

پژوهشگر ارشد

• Cancer Metabolism
• Prostate Cancer
• Insulin Resistance
• +۶ مورد دیگر

Dr. Jennifer Gunter is a Senior Research Fellow at Queensland University of Technology (QUT), affiliated with the Faculty of Health and the School of Biomedical Sciences. Her research focuses on metabolic plasticity in cancer cells, particularly prostate cancer, and the interplay between metabolic disorders and cancer progression. She completed her PhD in 2005 at the University of Oxford, studying lipid metabolism in type-2 diabetes, and has since held postdoctoral positions at the University of Queensland and QUT. Her work integrates metabolomics, cell biology, and clinical translation to identify therapeutic targets. Key areas include insulin resistance, androgen receptor signaling, and drug discovery. Dr. Gunter has secured over $7.9 million in competitive grants and published over 20 peer-reviewed articles, reviews, and book chapters. Her team explores adaptive metabolic pathways in response to therapies like androgen deprivation and biguanides. Dr. Gunter collaborates on projects involving biomaterials (e.g., hydrogel models) and nanoparticle drug delivery. Her research highlights the importance of metabolic reprogramming in treatment resistance and metastasis. She also investigates the role of leptin and cytokines in tumor progression. Future work aims to translate findings into personalized therapies for urological cancers.