جست‌وجوی استاد و پژوهشگر

Lars Maegdefesselمشاهده پروفایل

استاد

• Vascular Biology
• Cardiovascular Disease
• Atherosclerosis
• +۳ مورد دیگر

Prof. Lars Mägdefessel is a Professor of Vascular Biology at the Technical University of Munich (TUM), leading the Molecular Vascular Biology group within the TUM School of Medicine and Health. His research focuses on non-coding RNAs in vascular diseases, particularly atherosclerosis and aortic aneurysms, using translational approaches for molecular treatment discovery. He holds an MD from Johannes Gutenberg University (Mainz, Germany), completed cardiology clinical training, and postdoctoral research at Stanford University before joining TUM in 2016. Education: MD from Johannes Gutenberg University, Mainz Postdoctoral training at Stanford University, USA Assistant Professor at Karolinska Institute, Sweden Research Interests: Non-coding RNA regulation in vascular pathology Mechanisms of atherosclerotic plaque vulnerability Translational therapies for vascular diseases Advanced aortic aneurysm progression Awards include the ERC Consolidator Grant (2023), Russell Ross Award (2023), and Heisenberg Professorship (2016). His lab is supported by the German Center for Cardiovascular Research (DZHK).

• Molecular Biology
• Biochemistry
• Cell Biology
• +۵ مورد دیگر

Dr. Maruf Ali is an Associate Professor in Molecular and Structural Biology at Imperial College London's Department of Life Sciences, part of the Faculty of Natural Sciences. He holds affiliations with the Centre for Structural Biology, Electron Microscopy Centre, and Membrane Biology. His research focuses on understanding molecular mechanisms of protein quality control during cellular stress, particularly in cancer and neurodegenerative diseases. Research interests include the Unfolded Protein Response (UPR), ER stress signaling pathways, and therapeutic interventions targeting these mechanisms. His multidisciplinary approach combines structural biology, biochemistry, and cellular techniques to study proteins and complexes involved in ER stress responses. Notable affiliations include the Membrane Biology and Molecular Mechanisms of Disease groups. His work explores how the UPR is activated and propagated, with implications for developing novel treatments for diseases linked to protein misfolding. Recent studies emphasize drug repurposing strategies targeting RSK4 to combat chemoresistance in cancers like lung and bladder cancer, as well as identifying key regulators of ER stress pathways such as IRE1 and PERK. Laboratory activities are centered at the Ali Lab (http://www.imperial.ac.uk/ali-lab), where research integrates structural insights with functional studies to advance understanding of cellular stress responses and their therapeutic applications.

Andreas Herzمشاهده پروفایل

استاد

• Computational Neuroscience
• Neural Coding
• Spatial Navigation
• +۳ مورد دیگر

Prof. Dr. Andreas Herz is a Chair in Computational Neuroscience at the Faculty of Biology, Ludwig-Maximilians-Universität München (LMU). His research focuses on understanding neural mechanisms underlying spatial navigation, temporal cognition, and sensory processing. He leads the Computational Neuroscience group and collaborates with the Bernstein Center for Computational Neuroscience Munich. Research Interests: Dr. Herz investigates how neural systems encode spatial and temporal information, including grid cells, head-direction systems, and neural coding strategies. His work bridges experimental neurophysiology with theoretical modeling, addressing topics like cognitive maps, neural variability, and synaptic plasticity. Teaching & Mentorship: He oversees advanced courses on computational neuroscience and neurophysiology, fostering interdisciplinary training for graduate students. His research group includes prominent collaborators like Dr. Martin Stemmler and PD Dr. Kay Thurley, focusing on projects involving neural network dynamics and behavioral neuroscience. Publications & Impact: Over 85 peer-reviewed articles highlight his contributions to understanding entorhinal-hippocampal circuits, dendritic processing, and neural representation of space/time. Key work includes studies on grid cell variability, zebrafish spatial memory, and cytoskeletal organization in dendritic spines.

• Respiratory diseases
• Epigenetics
• Molecular Biology
• +۵ مورد دیگر

Senani N.H. Rathnayake is a Research Fellow at the University of Technology Sydney (UTS), Faculty of Science. He completed his PhD at UTS (2019-2024) and held a Postdoctoral Fellowship at the University of Groningen (2023-2024). His primary research focuses on respiratory diseases, particularly the molecular mechanisms of smoking-induced lung damage, COPD, and asthma. Key areas include gene expression profiling, epigenetic changes, and cellular responses to cigarette smoke exposure. Research Interests: Transcriptomic and epigenetic alterations in lung diseases Smoking cessation effects on airway biology Genetic regulation of COPD biomarkers (e.g., sRAGE) Sex chromosome influences on respiratory disease susceptibility Awards & Fellowships: 2023 TSANZ Past Presidents Scholarship Award 2022-2023 European Respiratory Society Short-Term Fellowship Recent Research Trends: His articles emphasize smoking's impact on bronchial epithelial cells, including transcriptomic shifts, mucus barrier dynamics, and CRISPR-based gene-editing applications. Recent work explores Y-chromosome effects on COPD and asthma pathogenesis. Professional Engagement: Co-chair of the 2023 TSANZ Annual Scientific Conference Member of Australian Society for Medical Research, European Respiratory Society, and Thoracic Society of Australia and New Zealand

• Molecular Biology
• Cell Biology
• Autophagy
• +۳ مورد دیگر

Prof. Dr. Christian Ungermann is a Professor in the Department of Biochemistry at the University of Osnabrück, Germany. His research focuses on the molecular mechanisms underlying endosome, lysosome, and autophagosome biogenesis. He combines cell biological methods with in vitro reconstitution assays to study protein complexes involved in these processes. His work is critical for understanding disease-related mechanisms linked to organelle dysfunction. Research topics include endosomal maturation, autophagosome/lysosome biogenesis, and endosomal signal transduction. Model systems include Saccharomyces cerevisiae, insect cells, and Drosophila melanogaster. Key methods are protein purification, fluorescence microscopy, membrane fusion assays, and enzymatic activity assays. Recent publications highlight studies on Rab GTPase regulation, endosomal Rab transitions, and CORVET tethering complex structure, reflecting expertise in membrane trafficking and organelle dynamics.

• Redox Biology
• Cancer Research
• Drug Metabolism
• +۴ مورد دیگر

Zhiwei Ye is an Associate Professor in the Department of Pharmacology & Immunology at the College of Medicine, Medical University of South Carolina. His research focuses on redox biology, cancer mechanisms, and drug metabolism with a particular emphasis on mitochondrial function, oxidative stress, and therapeutic resistance. He holds a PhD in Pharmaceutical Science from Katholieke Universiteit Leuven (Belgium, 2009) and prior degrees from Zhejiang University (China). PhD in Pharmaceutical Science, 2009 – Katholieke Universiteit Leuven, Belgium Master in Pharmaceutical Science, 2005 – Katholieke Universiteit Leuven, Belgium Master in Medicine, 2003 – Zhejiang University, China B.S. in Pharmacy, 2000 – Zhejiang University, China Dr. Ye’s research explores how redox regulation impacts cancer progression, drug resistance, and metabolic disorders. His work integrates enzymology (e.g., GSTP, PDI), mitochondrial dynamics, and zebrafish models to study mechanisms like S-glutathionylation, VDAC targeting, and drug-transporter interactions. Recent studies highlight novel therapeutic strategies for hepatocellular carcinoma, melanoma, and myeloma through modulation of redox pathways. Publications emphasize translational research bridging basic biology and clinical applications, including drug development (e.g., Telintra) and understanding treatment resistance in malignancies. His work also addresses metabolic disease mechanisms, such as hepatic steatosis and drug-induced renal toxicity. No scientific awards explicitly mentioned in provided texts. Active in grant-funded research areas like cancer biology and redox signaling. Collaborates on projects involving drug-transporter profiling in hepatocytes and cellular stress responses.

• Metabolomics
• Antibiotic Resistance
• Biotechnology
• +۵ مورد دیگر

Per Bruheim is a Professor at the Department of Biotechnology and Food Science, Norwegian University of Science and Technology (NTNU). He leads the Bruheim research group, focusing on Deep Phenotyping of prokaryotic and eukaryotic systems using advanced metabolomics, fluxomics, and lipidomics techniques. He is the scientific leader of the NV faculty Mass Spectrometry lab and has developed targeted/non-targeted MS methods applied to diverse biological systems. Teaching roles include leading the 2-year and 5-year Biotechnology programs (MSBIOTECH and MBIOT5). He teaches courses such as TBT4140 Biochemical Engineering, TBT4110 Microbiology, and TKP4170 Process Design. Current research projects include targeting antibiotic resistance via bacterial stress responses (Trond Mohn Foundation), chemically defined cell culture media development, and peptide drug inhibition of translesion synthesis mechanisms. Research interests center on metabolomics and systems biology approaches to study microbial physiology and antibiotic resistance, with applications in bioprocessing and sustainable protein production. His lab employs mass spectrometry for precise metabolic profiling and collaborates internationally on projects involving lipidomics and flux analysis. Advising and grants involve mentoring over a dozen master’s theses on topics like microbial fermentation optimization, single-cell protein production, and recombinant protein expression. He actively pursues funding for projects addressing AMR mechanisms and bioprocess innovation. The Bruheim group also collaborates with industry on sustainable raw material utilization for microbial cultures. Labs/Teams: Leads the Mass Spectrometry facility at NTNU and directs the Bruheim research group within the Institute of Biotechnology (IBT). Collaborates with national/international partners in microbiology, metabolomics, and bioprocessing.

Bo Liمشاهده پروفایل

استاد

• Neuroscience
• Neural circuits
• Synaptic plasticity
• +۱۲ مورد دیگر

Bo Li is the Robert Lourie Professor of Neuroscience at Cold Spring Harbor Laboratory (CSHL) in the School of Biological Sciences. His research focuses on the neural circuits underlying cognitive function and dysfunction related to anxiety, depression, schizophrenia, and autism, with particular emphasis on synaptic mechanisms and rodent behavioral models. He earned his Ph.D. in Neuroscience from the University of British Columbia in 2003. Education: Ph.D., Neuroscience, University of British Columbia (2003) M.Sc., Psychology, Chinese Academy of Sciences (1997) B.Sc., Medicine, Jining Medical College (1992) Li's lab integrates in vitro and in vivo electrophysiology, imaging, molecular and genetic techniques, optogenetics, and chemogenetics to probe fear and reward circuits in rodent brains. His work examines how these circuits contribute to adaptive and maladaptive behaviors, with significant implications for understanding mental disorders. Recent publications highlight his exploration of the vitamin B6 pathway in cancer, opioid neuropeptide dynamics in motivation, and area postrema neurons in brain-body interactions. His research also addresses salience assignment through striatal-amygdala circuits and dietary choice regulation via neurotensin neurons in the extended amygdala. Scientific awards include: HFSP Research Grant awards 2015 NARSAD Independent Investigator grant WSBS Teaching Award 2015 Students in his lab include Sara Boyle, Mingzhe Liu, and Danielle van de Lisdonk. His work has been supported by NIH BRAIN Initiative grants and involves collaborations across multiple CSHL laboratories.

Michael Rosenzweigمشاهده پروفایل

دانشیار

• Multiple Myeloma
• Amyloidosis
• Hematology
• +۵ مورد دیگر

Michael Rosenzweig, M.D., M.S., serves as Associate Professor and Chief of the Division of Multiple Myeloma in the Department of Hematology & Hematopoietic Cell Transplantation at City of Hope. A board-certified hematologist-oncologist, he directs the amyloidosis program and specializes in plasma cell disorders including multiple myeloma, AL amyloidosis, Waldenstrom macroglobulinemia, and POEMS syndrome. His educational background includes: B.A. in Psychology from Emory University (1989-1993) M.S. in Physiology and Biophysics (1993-1994) M.D. from University of Arizona College of Medicine (1997-2001) Internal Medicine Residency and Hematology/Oncology Fellowship at Boston Medical Center (2001-2009) Bone Marrow Transplantation Fellowship at Memorial Sloan Kettering Cancer Center (2009-2011) Dr. Rosenzweig's research focuses on novel therapeutic strategies for plasma cell disorders, with particular emphasis on smoldering myeloma intervention and amyloidosis treatment optimization. He actively investigates drug repurposing (leflunomide), monoclonal antibodies (daratumumab), and CAR-T therapies targeting CS1 for light chain amyloidosis. His clinical work involves multidisciplinary collaboration with cardiology, nephrology, and neurology for comprehensive amyloidosis management. His publication record demonstrates consistent focus on translational and clinical research in plasma cell malignancies, with recent work spanning from preclinical CAR-T studies to phase I/II trials of novel combinations for relapsed/refractory disease. Key themes include treatment sequencing, biomarker development, and addressing rare amyloid subtypes. Scientific recognition includes: 2021 IDEA Grant for AL amyloidosis detection 2020 Pfizer grant for TTR amyloidosis management (Co-PI) 2018 Steven Gordon Innovation Grant 2015 David Seldin Research Grant 2013 ASBMT Clinical Research Scholar As an educator, Dr. Rosenzweig mentors hematology-oncology fellows and leads clinical trials through industry partnerships and investigator-initiated grants. His current research portfolio emphasizes diagnostic pathway optimization and therapeutic strategies for precursor conditions. He practices at Duarte Cancer Center with active involvement in the plasma cell disease team and hematopoietic cell transplantation program.

Gabriele Schragمشاهده پروفایل

استاد

• MEMS Technology
• Microfluidics
• Acoustic Sensors
• +۳ مورد دیگر

Prof. Gabriele Schrag holds the Professorship of Microsensors and Actuators at the Technical University of Munich (TUM), within the TUM School of Computation, Information and Technology. Her research focuses on MEMS (Micro-Electro-Mechanical Systems), including microsensors, actuators, and their applications in acoustics, microfluidics, and bioengineering. She has pioneered work in virtual prototyping for system-level modeling to enhance device robustness and performance. Education: PhD (summa cum laude) from TUM on 'Modeling coupled effects in microsystems' Habilitation in sensor systems technology (2018) Acting head of the Chair of Technical Electrophysics (2018-2023) Research emphasizes acoustic MEMS transducers , electrohydrodynamic printing , and physics-based modeling . Notable projects include developing piezoelectric MEMS microphones with corrugated membranes and integrated micropump systems. Awards include the Bavarian Prize for Good Teaching (2021) and Eurosensors Fellow Award (2019). Her work bridges virtual prototyping with real-world applications , addressing challenges in miniaturization, energy efficiency, and sensor integration for medical and industrial systems.

Sebastian Schlückerمشاهده پروفایل

استاد

• Surface-Enhanced Raman Spectroscopy (SERS)
• Plasmonics
• Nanophotonics
• +۱۲ مورد دیگر

Prof. Dr. Sebastian Schlücker is a full professor in the Department of Physical Chemistry at the University of Duisburg-Essen , where he leads the Molecular Biophotonics and Nanodiagnostics research group within the Faculty of Chemistry. He is actively engaged in research, teaching, and academic leadership, with a strong focus on advanced spectroscopic techniques for biomedical and analytical applications. His research interests lie at the intersection of nanophotonics, plasmonics, and bioanalytical chemistry . Key areas include surface-enhanced Raman spectroscopy (SERS) , single-particle spectroscopy , laser diagnostics , and the design of functionalized metal colloids for biosensing and tumor diagnostics. He emphasizes a theory-guided approach combining simulation and experiment to tailor nanoparticle properties. His recent publications (2023–2025) reflect a strong trend toward quantitative, label-free molecular diagnostics , point-of-care testing , and in situ monitoring of catalytic and biological processes . The work spans fundamental plasmonics to clinical applications, particularly in cancer detection and immunoassays using SERS nanotags. International Raman Innovation Prize He mentors students and researchers, supervises theses, and collaborates widely across disciplines. His group develops advanced instrumentation, including portable SERS readers , fs-laser laboratories , and automated nanoparticle synthesis systems (e.g., BONAPARTE robot). He teaches master’s courses such as NanoBioPhotonics and Optical Spectroscopy , and is involved in STEM outreach.

Premdass Ramdasمشاهده پروفایل

مدرس ارشد

• Cancer Cell Biology
• Quantitative Proteomics
• Genomics
• +۱۲ مورد دیگر

Dr. Premdass Ramdas is a Senior Lecturer at Monash University Malaysia, affiliated with the Jeffrey Cheah School of Medicine and Health Sciences. He joined in October 2023 with over 13 years of experience in medical biotechnology and health sciences, focusing on cancer research and bioactive natural compounds. PhD in Cancer Proteomics and Genomics, University of Malaya MSc in Medical Sciences (Cancer Genomics and Natural Products), International Medical University BSc with First-Class Honors His research focuses on the anticancer mechanisms of tocotrienols, utilizing proteomics, genomics, bioinformatics, and mouse models. He explores epigenetics, nutrigenomics, RNA/microRNA analysis, exosome biology, and AI-driven big data in cancer. His work contributes to UN Sustainable Development Goals in health and well-being. Recent publications show a strong trend in systematic reviews and mechanistic studies on vitamin E analogues in cancer, particularly colorectal and breast cancers. His research integrates molecular biology with computational approaches, including molecular docking and data mining. First-class honors for BSc Malaysian Palm Oil Board Scholarship for MSc MyBrain15 Scholarship for PhD Dr. Ramdas has secured research grants such as FRGS and actively supervises research projects. He is currently accepting PhD students and has co-supervised non-HDR reviews, indicating active mentorship. He has no known labs or teams explicitly mentioned, but collaborates extensively, particularly with Prof. Radhakrishnan A.K.

• Microbial Pathogenesis
• Gut Microbiome
• Drug Metabolism
• +۳ مورد دیگر

Andrew L. Goodman, PhD, is the C.N.H. Long Professor and Chair of the Department of Microbial Pathogenesis at Yale School of Medicine. He is also Director of the Yale Microbial Sciences Institute. His research focuses on understanding how gut microbes influence human health, particularly in drug metabolism, host-pathogen interactions, and microbiome ecology. Goodman earned his BA in Ecology and Evolutionary Biology from Princeton University, his PhD in Microbiology from Harvard University, and completed postdoctoral training at Washington University. His lab develops innovative tools such as transposon insertion sequencing (INSeq) and personalized microbiota culture collections. Key contributions include discovering microbiome-driven drug metabolism pathways, mechanisms of bacterial resilience during infection, and bacterial competition strategies. His work has been recognized with awards including the NIH Director’s New Innovator Award and the Presidential Early Career Award in Science and Engineering. Recent research highlights include studies on GPCR-targeted drug modulation by gut microbes (2025), protein-folding mechanisms in bacterial competition (2025), and microbiome responses to time-restricted feeding (2023). Goodman collaborates with institutions like the Diabetes Research Center and Yale Cancer Center, advancing translational microbiome research. Awards: ASPET John J. Abel Award, HHMI Faculty Scholar, Pew Foundation Labs/Teams: Goodman Lab, Yale Microbial Sciences Institute Grants: NIH, Burroughs Wellcome Foundation, HHMI

David A. Hoodمشاهده پروفایل

استاد

• Cell Physiology
• Mitochondrial Biology
• Skeletal Muscle Physiology
• +۹ مورد دیگر

David A. Hood is a Full Professor and former Canada Research Chair in Cell Physiology (2003–2024) at York University, affiliated with the School of Kinesiology and Health Science. He is the Founding Director of the Muscle Health Research Centre (MHRC) and supervises graduate students in the Biology Graduate Program. Research Interests: His research focuses on mitochondrial biogenesis, turnover, and function in skeletal muscle. He investigates how exercise, aging, and muscle disuse affect mitochondrial health, with a particular interest in mitophagy, lysosomal function, and cellular signaling. His work spans human, animal, and cellular models, integrating physiological, biochemical, and molecular biology approaches. Recent Publication Trends: Recent publications emphasize transcriptional regulation (e.g., TFEB, TFE3, ATF4, p53), organelle crosstalk (mitochondria-lysosome interactions), and the role of exercise as 'mitochondrial medicine.' His lab explores therapeutic interventions like mitochondrial transplantation and nutrient signaling in muscle health. Scientific Awards: Canada Research Chair in Cell Physiology (2003–2024) Finalist for a prestigious national award Advising and Grants: Dr. Hood actively mentors graduate students and postdoctoral fellows. He has secured significant funding, including a $1 million CIHR grant to study mitochondria and lysosomes in muscle. His lab fosters interdisciplinary collaboration and contributes to major reviews in the field. Labs and Teams: He leads the Hood Lab at York University and co-founded the Muscle Health Research Centre (MHRC), a multidisciplinary hub promoting research on muscle function, exercise, and aging. The MHRC facilitates collaboration across departments and institutions.

Freddy Radtkeمشاهده پروفایل

استاد

• Molecular Biology
• Cellular Biology
• Cancer Research
• +۹ مورد دیگر

Freddy Radtke is a Full Professor at the School of Life Sciences at École polytechnique fédérale de Lausanne (EPFL), where he leads the Radtke Lab (UPRAD) within the Swiss Institute for Experimental Cancer Research (ISREC). He holds multiple affiliations across EPFL, including in the SSV-ENS and EDMS-ENS programs, reflecting his broad engagement in teaching and doctoral education in life sciences. His research is centered on the molecular mechanisms of stem cell maintenance and differentiation, particularly through the Notch signaling pathway. His work spans several self-renewing systems: the hematopoietic system, skin, and gut. Key findings include the identification of Delta-like 4 as the essential Notch1 ligand for T cell commitment, the tumor suppressor role of Notch1 in skin, and its critical function as a gatekeeper of intestinal progenitor cells by repressing CDK inhibitors. These discoveries have significant implications for understanding cancer development and regenerative processes. The recent publications highlight a consistent focus on Notch signaling across diverse biological contexts—hematopoiesis, skin development, intestinal regeneration, and stem cell systems biology. The keywords and subfields reflect deep mechanistic investigations into cell fate decisions, signal transduction, and tissue homeostasis, with strong translational relevance to cancer and inflammatory diseases. Freddy Radtke has mentored numerous Ph.D. students and is actively involved in teaching courses such as Stem Cells and Organoids and Scientific Project Design in Translational Oncology . His lab conducts research supported by external funding, and he collaborates across disciplines to integrate systems biology with stem cell research. The lab includes scientists, doctoral assistants, technicians, and administrative staff, indicating a vibrant and multidisciplinary research team.