جستجوی استاد راهنمای دانشگاهی

Prof. Thomas Kuner is a Professor and Director of the Department of Functional Neuroanatomy at the University of Heidelberg's Medical Faculty. He holds a medical degree (MD) from Heidelberg (1998) and completed postdoctoral work at Duke University and the Marine Biological Laboratory. Since 2000, he has led a research group at the Max Planck Institute for Medical Research, followed by habilitation in Physiology (2003) and appointment as Professor of Anatomy and Cell Biology (2006). Research Focus: His work focuses on neuroanatomy, synaptic transmission mechanisms, and pain research. Key projects include investigations into the structural and functional properties of synapses (e.g., calyx of Held), the role of presynaptic proteins like Mover, and the molecular basis of pain signaling via the SFB 1158 consortium. His lab uses advanced imaging techniques (e.g., STED microscopy) and genetic models to study neuronal circuits and synaptic plasticity. Funding & Collaborations: Kuner's research is supported by grants from the DFG (e.g., SFB 1158), the Baden-Württemberg Foundation, and other national/international bodies. His interdisciplinary approach bridges cellular neuroscience, molecular biology, and clinical applications in pain management. Teaching & Leadership: He oversees the Institute of Anatomy and Cell Biology, contributing to graduate programs in medical education and anatomy. His team includes postdocs and technicians, with collaborations extending to imaging technology development and medical education innovation.

• Neuroscience
• Neurophysiology
• Pain Research
• +۳ مورد دیگر

Sophie Lanone is a researcher and team leader of the Genetic-environment Interactions in COPD, Cystic Fibrosis, and Respiratory Pathologies (GEIC2O) team at the Mondor Institute of Biomedical Research (IMRB), affiliated with Université Paris-Est Créteil. Her work focuses on understanding the interplay between genetic and environmental factors in respiratory diseases, particularly COPD, cystic fibrosis, and surfactant-related pathologies. She leads a multidisciplinary team of clinicians and scientists investigating molecular mechanisms, inflammation resolution, and environmental impacts on pulmonary health. Key research themes include the molecular basis of cigarette smoke-induced COPD, genetic and cellular aspects of cystic fibrosis, and the role of specialized pro-resolving mediators in disease. Funding sources include EU programs (e.g., H2020 REMEDIA), ANR, and patient associations like Vaincre la Mucoviscidose. Recent advances include identifying lipid mediator defects in CF patients and demonstrating resolvin E1’s efficacy in correcting ciliary dysfunction. Team members have received awards, such as Khadeeja Adam Sy’s 2024 prize for active participation in CF research. Collaborations span in vitro/ex vivo models, patient cohort studies, and translational approaches toward personalized therapies. The team also explores environmental exposures (e.g., asbestos, nanoparticles) and their long-term respiratory health impacts.

• Genetic-Environment Interactions
• Cystic Fibrosis
• Respiratory Pathologies
• +۳ مورد دیگر

Per Bruheim is a Professor at the Department of Biotechnology and Food Science, Norwegian University of Science and Technology (NTNU). He leads the Bruheim research group, focusing on Deep Phenotyping of prokaryotic and eukaryotic systems using advanced metabolomics, fluxomics, and lipidomics techniques. He is the scientific leader of the NV faculty Mass Spectrometry lab and has developed targeted/non-targeted MS methods applied to diverse biological systems. Teaching roles include leading the 2-year and 5-year Biotechnology programs (MSBIOTECH and MBIOT5). He teaches courses such as TBT4140 Biochemical Engineering, TBT4110 Microbiology, and TKP4170 Process Design. Current research projects include targeting antibiotic resistance via bacterial stress responses (Trond Mohn Foundation), chemically defined cell culture media development, and peptide drug inhibition of translesion synthesis mechanisms. Research interests center on metabolomics and systems biology approaches to study microbial physiology and antibiotic resistance, with applications in bioprocessing and sustainable protein production. His lab employs mass spectrometry for precise metabolic profiling and collaborates internationally on projects involving lipidomics and flux analysis. Advising and grants involve mentoring over a dozen master’s theses on topics like microbial fermentation optimization, single-cell protein production, and recombinant protein expression. He actively pursues funding for projects addressing AMR mechanisms and bioprocess innovation. The Bruheim group also collaborates with industry on sustainable raw material utilization for microbial cultures. Labs/Teams: Leads the Mass Spectrometry facility at NTNU and directs the Bruheim research group within the Institute of Biotechnology (IBT). Collaborates with national/international partners in microbiology, metabolomics, and bioprocessing.

• Metabolomics
• Antibiotic Resistance
• Biotechnology
• +۵ مورد دیگر

Professor Tracy Bryan is a Professor in the Faculty of Medicine and Health at the University of Sydney and serves as Unit Head of the Cell Biology Unit at the Children's Medical Research Institute (CMRI). She holds a Bachelor of Science from Macquarie University and a PhD from the CMRI, where her groundbreaking research identified the ALT (Alternative Lengthening of Telomeres) mechanism in cancer cells. After postdoctoral work with Nobel Laureate Tom Cech at the University of Colorado, she returned to Australia in 2001 to establish her research group at CMRI. Her research focuses on telomerase biology, particularly its role in cancer progression and bone marrow failure syndromes. Key themes include understanding telomerase mechanisms, developing inhibitors for cancer therapy, and investigating telomere biology disorders. Her work integrates biochemical and cell-based approaches, supported by grants from NHMRC, Viertel Foundation, and Cancer Council NSW. Recent publications highlight advancements in telomerase-substrate interactions, i-motif DNA structures, and the interplay between telomere maintenance and DNA damage responses. Major grants include NHMRC Ideas Grants targeting telomere-related bone marrow failure and ARC Discovery Projects exploring DNA replication-telomere links. Bryan’s research group collaborates internationally, contributing to translational studies in oncology and regenerative medicine. Her lab’s work is detailed at CMRI’s Cell Biology Team page, with ongoing projects focused on telomerase inhibition strategies and molecular mechanisms of telomere dysfunction.

• Cancer Biology
• Biochemistry
• Telomere Biology
• +۴ مورد دیگر

Dr. Amin Reza Rajabzadeh is an Associate Professor at the W Booth School of Engineering Practice and Technology, McMaster University, with affiliate roles in the McMaster School of Biomedical Engineering and Mechanical Engineering. He specializes in biochemical engineering, focusing on biosensors, bioseparation processes, and bioprocess monitoring. His research includes developing biosensors for biological process monitoring and nanotechnology-based cancer therapies. He holds a Professional Engineer license (P.Eng.) and is a member of the Canadian and American Engineering Education Associations. Dr. Rajabzadeh's teaching spans core biochemical engineering courses like Bioreactor Design and Bioprocess Control. He has received the McMaster President’s Award for Teaching and a MacPherson Leadership in Teaching Fellowship. His research clusters span Energy, Environment, Health & Bio-innovation, and Micro-Nano Systems. Recent work includes nanoplatforms for photothermal cancer therapy (ACS Applied Materials & Interfaces, 2021) and innovations in sustainable protein enrichment via tribo-electrostatic separation. Collaborations span biomaterials, environmental engineering, and nanotechnology. Awards: Teaching Excellence Awards, Leadership Fellowships Research Themes: Biosensors, Nanomedicine, Bioseparation Technologies Labs/Teams: Biomedical Engineering Research Group, Nanotechnology Applications Lab

• Biochemical Engineering
• Biosensors
• Separation Processes
• +۷ مورد دیگر

Kathryn E. Dickerson, M.D., M.S.C.S., is an Assistant Professor in the Department of Pediatrics at UT Southwestern Medical Center, specializing in the Division of Hematology and Oncology. She holds dual appointments as a 2015 Translational Research Scholar in the UTSW Center for Translational Medicine and as an NIH KL2 scholar. Her clinical focus is pediatric hematology, emphasizing bone marrow failure disorders, cancer predisposition syndromes, and thalassemia/dyserythropoietic anemias. Her research investigates epigenetic regulation of myeloid malignancies, clonal hematopoiesis in childhood cancer survivors, and molecular mechanisms underlying acute myeloid leukemia (AML), myelodysplastic syndromes (MDS), and myeloproliferative disorders (MPD). Education: Bachelor's in Biochemistry (Indiana University), minor in Spanish Medical degree (Indiana University School of Medicine) Masters of Science in Clinical Sciences (UT Southwestern Center for Translational Medicine) Training: Pediatric residency with research pathway (Ohio State University/Nationwide Children’s Hospital) Pediatric hematology-oncology fellowship (UT Southwestern) Dr. Dickerson’s research bridges basic science and clinical practice, leveraging CRISPR-based epigenetic editing, genomic analysis, and translational studies to understand disease mechanisms. Key projects include interrogating enhancer dysregulation in leukemia, studying metabolic reprogramming in cancers, and evaluating clonal hematopoiesis in survivors of childhood cancers. Her work has advanced understanding of EZH2’s role in AML and identified therapeutic vulnerabilities in myeloid malignancies. Awards: 2015 Translational Research Scholar (UTSW Center for Translational Medicine) NIH KL2 Career Development Award Grants/Initiatives: NIH-funded investigator-initiated study on clonal hematopoiesis Industry/consortia-sponsored trials for bone marrow failure and rare blood disorders She collaborates with the Children’s Research Institute and North American Pediatric Aplastic Anemia Consortium, contributing to clinical trials and translational initiatives. Her lab focuses on developing biomarkers for disease severity (e.g., immature platelet fraction in pediatric COVID-19) and therapeutic strategies targeting epigenetic dependencies in leukemia.

• Pediatric Hematology
• Myeloid Malignancies
• Epigenetic Regulation
• +۴ مورد دیگر

Jan-Michael Peters is a leading academic affiliated with the Research Institute of Molecular Pathology (IMP) , Vienna, Austria. He has held pivotal roles including Scientific Director (2013–present) , Scientific Deputy Director (2011–2012) , and Senior Scientist (2002–2010) . His academic journey includes a Ph.D. in Cell Biology (1991) from the University of Heidelberg and postdoctoral work at Harvard Medical School and the German Cancer Research Center. 1985 : Prediploma in Biology, University of Kiel 1988 : Diploma in Biology, University of Heidelberg 1991 : Ph.D. in Cell Biology, University of Heidelberg His research focuses on cell cycle regulation , chromosome biology , mitosis , and ubiquitin-dependent proteolysis , contributing to developmental biology and molecular mechanisms. Notable scientific accolades include the Wittgenstein Prize (2011) , EMBO Young Investigator Award (2001) , and Mendel Lecture (2008) . He has been a member of the Austrian Academy of Sciences since 2012.

• Cell cycle
• Chromosome biology
• Mitosis
• +۱ مورد دیگر

Hien Nguyen is the Carl Johnson/Pfizer Professor of Organic Chemistry at Wayne State University, holding joint appointments in the Department of Chemistry and the Department of Oncology's Molecular Therapeutic Program. His research program bridges chemistry and biology to develop novel therapeutic approaches for cancer, Alzheimer's disease, and diabetes through innovative carbohydrate chemistry. His educational background includes: B.S. in Chemistry from Tufts University (1996) Ph.D. in Organic Chemistry from University of Illinois at Urbana-Champaign (2003) NIH Postdoctoral Fellowship at Stanford University (2003-2006) Prof. Nguyen's research focuses on medicinal chemistry, cancer drug discovery, chemical biology, and organic synthesis, with particular expertise in vaccine adjuvant immunotherapy, Alzheimer's disease therapeutics, diabetes treatments, and catalytic stereoselective carbohydrate methods. His lab develops novel methodologies for oligosaccharide assembly and applies them to create carbohydrate-based therapeutics targeting heparanase and other biological pathways involved in disease progression. His recent publications demonstrate a strong focus on phenanthroline-catalyzed stereoselective glycosylations, heparan sulfate mimetics for therapeutic applications, transition-metal catalyzed asymmetric synthesis, and the development of carbohydrate-based inhibitors for heparanase. These works span organic chemistry methodology, medicinal chemistry, and biochemical applications, reflecting his interdisciplinary approach to solving complex biological problems through chemical innovation. Among his notable awards are: 2018 Carl Johnson Endowed Chair 2018 Horace S. Isbell Award for Excellence in Carbohydrate Research 2016 Mitzutani Glycoscience Innovation Award 2012 International Young Carbohydrate Investigator Award Prof. Nguyen has successfully mentored numerous graduate students and postdoctoral fellows who have gone on to successful careers in academia and industry. His research is supported by multiple NIH grants including R01AI169505 "Synthesis and Evaluation of Carbohydrate Vaccine Adjuvants" (2022-2027) and R35GM149213 "Development of Catalytic Glycosylations and Biologically Important Glycosaminoglycans" (2023-2028). His group actively pursues both fundamental methodology development and translational applications of carbohydrate chemistry. The Nguyen research group operates state-of-the-art organic synthesis and biochemical characterization facilities, with strong collaborations across Wayne State University including the School of Medicine. The group maintains active partnerships with researchers at other institutions and pharmaceutical companies to advance their therapeutic discoveries toward clinical applications.

• Medicinal chemistry
• Cancer drug discovery
• Chemical biology
• +۹ مورد دیگر

Bjoern Bauer, PhD is a Professor in the Department of Pharmaceutical Sciences at the University of Kentucky, affiliated with the Sanders-Brown Center on Aging. His research focuses on blood-brain barrier (BBB) biology, Alzheimer’s disease mechanisms, and drug delivery strategies for neurological disorders. Bauer’s work explores how BBB dysfunction contributes to neurodegenerative diseases and cancer, with particular attention to efflux transporters like P-glycoprotein (ABCB1) and their roles in drug resistance and amyloid beta pathology. Key research areas include: 1) BBB leakage and its role in Alzheimer’s disease progression, 2) development of therapeutic strategies to modulate BBB transporters, 3) preclinical models of glioblastoma and neurodegeneration, and 4) biomarker discovery for early disease detection. His lab utilizes advanced in vitro BBB models, transgenic mouse models (e.g., 5xFAD), and imaging techniques to study these processes. Bauer’s contributions span over 40 peer-reviewed publications since 2001, with recent work emphasizing oxidative stress mechanisms, tumor drug resistance, and translational approaches to BBB targeting. Current efforts include investigating S100β as a plasma biomarker and exploring proteasome inhibition as a therapeutic avenue for restoring BBB integrity. He leads the Bauer-Hartz Lab, collaborating extensively with neurologists, oncologists, and pharmacologists to advance CNS drug delivery technologies. He holds a PhD in Pharmacology and has been a faculty member at the University of Kentucky since joining Sanders-Brown in [year not explicitly stated]. His research is supported by grants focusing on BBB biology, Alzheimer’s disease, and cancer pharmacology.

• Neuroscience
• Alzheimer’s Disease
• Blood-Brain Barrier Physiology
• +۳ مورد دیگر

Christopher D. Lima is a Professor and Chair of the Structural Biology Program at the Sloan Kettering Institute (SKI), Memorial Sloan Kettering Cancer Center (MSKCC), and an Investigator of the Howard Hughes Medical Institute. He holds the Alfred P. Sloan Chair. His research focuses on understanding the structural, biochemical, and functional mechanisms of macromolecules involved in post-translational protein modification by ubiquitin-like proteins (e.g., SUMO) and RNA processing pathways, including co- and post-transcriptional RNA maturation and decay. His lab employs cryo-electron microscopy (cryo-EM), X-ray crystallography, and biochemical reconstitution to study these processes. Education: PhD, 1994, Northwestern University BA, 1989, The Ohio State University Research Interests: Structural basis of ubiquitin and SUMO conjugation pathways Mechanisms of RNA surveillance and decay by the nuclear exosome Role of RNA processing in cell cycle control and disease Interactions between RNA helicases and exosome complexes Awards & Honors: Member, National Academy of Sciences (2020) Fellow of the American Academy of Arts and Sciences (2017) HHMI Investigator (2013) Louise and Allston Boyer Young Investigator (2006) Advising & Grants: Lima mentors numerous graduate students and postdoctoral researchers. His lab has received funding from the NIH, HHMI, and other institutions to support research into RNA processing and ubiquitin pathways. He collaborates widely, including with teams at MSKCC and other academic institutions. Labs & Teams: The Lima Lab is part of the Tri-Institutional PhD Program in Chemical Biology and the Gerstner Sloan Kettering Graduate School. The lab has made groundbreaking contributions to understanding SUMOylation and RNA exosome mechanisms, with key findings published in Nature , Cell , and Science .

• Structural Biology
• Biochemistry
• Macromolecular Structure
• +۶ مورد دیگر

Ling Zhao is a distinguished Professor at the School of Management, Huazhong University of Science and Technology, China, with extensive research contributions spanning artificial intelligence, machine learning, information systems, and biomedical applications. With over 150 publications since 2008, Dr. Zhao has established herself as a leading researcher in multiple interdisciplinary domains, particularly in applying computational methods to solve complex real-world problems. Dr. Zhao's research interests encompass a broad spectrum of cutting-edge topics including artificial intelligence, machine learning, data mining, control systems, and information systems. Her work demonstrates exceptional versatility, bridging theoretical computer science with practical applications in healthcare, transportation, cybersecurity, and business management. Notably, she has made significant contributions to sentiment analysis, medical image processing, algorithmic management, and privacy-preserving data analysis. Her research methodology often combines deep learning approaches with domain-specific knowledge to develop innovative solutions. Analysis of Dr. Zhao's recent publications (2023-2025) reveals a strong focus on interdisciplinary applications of AI, with particular emphasis on healthcare informatics (medical image analysis, disease diagnosis), human-computer interaction (algorithmic management effects), and advanced machine learning techniques (graph neural networks, multimodal learning). Her work shows a consistent trend toward increasingly complex and integrated systems that address real-world challenges across multiple domains. Dr. Zhao has made substantial contributions to academic advising and research mentorship, though specific student names aren't detailed in the available publications. Her research has been supported by various grants enabling work in AI applications, biomedical engineering, and information systems. Dr. Zhao maintains active collaborations with researchers across China and internationally, as evidenced by her co-authorship patterns. While specific laboratory information isn't explicitly mentioned in the publication records, Dr. Zhao appears to lead or be significantly involved in research groups focusing on AI applications in management and healthcare. Her work on medical imaging, sentiment analysis, and control systems suggests involvement in multiple specialized research teams addressing different application domains through computational approaches.

• Artificial Intelligence
• Machine Learning
• Data Mining
• +۵ مورد دیگر

Martin Wells is the Charles A. Alexander Professor of Statistical Sciences at Cornell University, with joint appointments in Social Statistics, Clinical Epidemiology, and Industrial Labor Relations. Since joining Cornell in 1987, he has developed methodologies spanning Bayesian inference, tensor analysis, and machine learning applications in biomedicine and finance. His research integrates statistical theory with computational innovations, particularly in high-dimensional modeling and quantum-inspired algorithms. Recent work focuses on geometric approaches to tensor decomposition, misclassification correction methods, and phylodynamic models incorporating dormancy effects. Professor Wells teaches statistical methodology across disciplines including law, medicine, and biology, adapting analytical frameworks to diverse research contexts. His interdisciplinary collaborations extend to Weill Medical College and the School of Industrial and Labor Relations.

• Statistical Inference
• Bayesian Methods
• Machine Learning
• +۱ مورد دیگر

Sandrine Dudoit is a Professor and Chair of the Department of Statistics at the University of California, Berkeley. She earned her PhD in Statistics from UC Berkeley in 1999 and joined the faculty in 2001. Her research focuses on statistical methodology and computing with applications to genomics, biomedical research, and precision health. She co-founded the Bioconductor Project , an open-source software initiative for biological data analysis, and leads interdisciplinary projects in single-cell transcriptomics and computational biology. Education: PhD in Statistics (UC Berkeley, 1999), M.Sc. in Mathematics (Carleton University, Canada). Research interests include high-dimensional statistical learning, single-cell RNA-Seq analysis, stem cell differentiation in the olfactory system, and statistical computing. She collaborates with biologists like John Ngai to study neuroepithelial regeneration using cutting-edge sequencing technologies. Recent work emphasizes trajectory inference, biomarker discovery, and methodological advances in handling high-dimensional genomic data. Her lab develops tools for normalization, clustering, and differential expression analysis in large-scale biological datasets. She teaches courses on statistical genomics and serves as a leader in UC Berkeley’s Division of Computing, Data Science, and Society (CDSS). Advising: Supervises PhD students in statistical methodology, computational biology, and bioinformatics. Grants: Active in securing funding for interdisciplinary research projects in genomics and data science. Labs/Teams: Core member of the Center for Computational Biology (CCB) and contributes to the Bioconductor community.

• Statistical Methodology
• Computational Biology
• Genomics
• +۵ مورد دیگر

Christian J. Hochstim, MD, PhD, is a Clinical Assistant Professor of Otolaryngology at the University of Southern California. His clinical expertise includes complex airway disorders, pediatric tracheostomy management, and vocal cord paralysis. He completed a pediatric otolaryngology fellowship at Stanford University and earned his PhD in developmental biology at Caltech. His research focuses on regenerative medicine strategies for airway reconstruction and preventing stenosis, leveraging stem cell technology. Dr. Hochstim’s education includes a dual MD/PhD, with postdoctoral training in head and neck cancer at Stanford. His research bridges developmental biology and clinical otolaryngology, addressing challenges in airway reconstruction and pediatric surgical outcomes. His clinical interests span aerodigestive disorders, obstructive sleep apnea, and cochlear implantation. He has published extensively on pediatric tracheostomy quality of life, biofilm-associated stenosis, and disparities in healthcare access. Notable studies include repurposing evolutionary gill gene programs for outer ear development and evaluating opioid-free anesthesia in OSA surgery. Key contributions include analyzing prognostic factors in pediatric fungal rhinosinusitis and investigating respiratory risks in endoscopic procedures. His work emphasizes translational research with clinical impact, particularly in underserved pediatric populations.

• Pediatric Otolaryngology
• Stem Cell Therapy
• Regenerative Medicine
• +۸ مورد دیگر

Bao-Zhu Yang is a Researcher at Yale School of Medicine , specializing in the Department of Psychiatry . With a PhD from University at Albany (2001), his work focuses on genetic mechanisms underlying psychiatric disorders. Positions: Research Scientist in Psychiatry Labs: Gelernter Lab, Division of Human Genetics His research explores gene-environment interactions , admixture mapping , and comorbid substance use-depression using linkage/association methods. Supported by NIH K01 funding, he investigates genetic bases for conditions including childhood depression , alcoholism , and PTSD . Recent publications highlight: Microbiome studies in methamphetamine use disorder (2023-2025) Genetic polymorphism analyses in NGF and GABAergic pathways (2020-2024) Network approaches to nicotine-alcohol comorbidity (2019) Epigenetic research on child maltreatment effects (2020) Scientific Recognition: Young Investigator Award (2011) from NARSAD Brain and Behavior Research Foundation Active grant support includes NIH K01 career development award for gene-mapping in comorbid disorders. Collaborates with leading researchers including Joel Gelernter and Hongyu Zhao across 30+ joint publications. His work spans 15+ years with recent focus on integrative -omics approaches to addiction psychiatry. Based at 300 George St, New Haven, CT , Yang's laboratory work involves genetic epidemiology , transcriptomic integration , and neurogenetic mapping of substance use disorders.

• Psychiatric Genetics
• Substance Use Disorders
• Gene-Environment Interaction
• +۵ مورد دیگر