Vibhu Sahniمشاهده پروفایل
استادیار
Vibhu Sahni, Ph.D., is an Assistant Professor of Neuroscience and Lab Director of the Laboratory for Cell Fate Specification and Circuit Development at the Burke Neurological Institute, an affiliate of Weill Cornell Medicine. His research focuses on understanding molecular mechanisms underlying corticospinal circuit development and regeneration, particularly after injuries like spinal cord injury or stroke. His work integrates developmental neuroscience principles to identify strategies for repairing neural circuits involved in motor control. Research interests include axon guidance, segment-specific neural circuit formation, and the molecular basis of neural regeneration decline during development. Key projects investigate how genes like Cbln1 direct axon targeting to thoraco-lumbar regions and why long-distance regenerative ability varies across spinal segments. Recent publications highlight discoveries in segmental axon targeting specificity and the dynamic loss of regenerative capacity in corticospinal neurons. His lab employs advanced techniques such as single-cell RNA sequencing, in vivo electroporation, and microsurgical lesion models to study these processes. Current grants include funding from the Craig H. Neilsen Foundation and Wings for Life Spinal Cord Research Foundation to advance molecular strategies for corticospinal circuit repair.











