Dr. Deyou Zheng is Professor in the Saul R. Korey Department of Neurology, Department of Genetics, and Dominick P. Purpura Department of Neuroscience at Albert Einstein College of Medicine. His research specializes in computational genomics and bioinformatics, analyzing high-throughput genomic data to understand genome structure, transcription regulation, and evolutionary dynamics during development and disease. Core research areas include: (1) Neural system development and neuropsychiatric disorders using iPSC-derived neurons and single-cell transcriptomics; (2) Genetic bases of congenital heart diseases; (3) Cancer genomics focusing on tumor microenvironment and immunotherapy resistance. Collaborative projects employ iPSC technology, RNA-seq, and CRISPR-Cas9 to model disorders like autism and schizophrenia. Recent publications emphasize: Single-cell integration algorithms for transcriptomic data Cancer-associated fibroblasts in glioblastoma/osteosarcoma CHD8 mutations in neurodevelopmental disorders Allele-specific expression in human brain cells










